Cited by 301Respiratory viral infections researchViral Infections and Immunology ResearchParvovirus B19 Infection Studies

The DOI matches its Crossref record; 83 of the 83 references it cites were found in a registry or an index.

Human Bocavirus: Passenger or Pathogen in Acute Respiratory Tract Infections?

Open access

Schildgen, Oliver, Müller, Andreas, Allander, Tobias, Mackay, Ian M., Völz, Sebastian, Kupfer, Bernd, Simon, Arne·2008·Clinical Microbiology Reviews

DOI 10.1128/cmr.00030-07PMC PMC2292574

Open this paper in CoChat — free account

Abstract

SUMMARY: Human bocavirus (HBoV) is a newly identified virus tentatively assigned to the family Parvoviridae , subfamily Parvovirinae , genus Bocavirus . HBoV was first described in 2005 and has since been detected in respiratory tract secretions worldwide. Herein we review the literature on HBoV and discuss the biology and potential clinical impact of this virus. Most studies have been PCR based and performed on patients with acute respiratory symptoms, from whom HBoV was detected in 2 to 19% of the samples. HBoV-positive samples have been derived mainly from infants and young children. HBoV DNA has also been detected in the blood of patients with respiratory tract infection and in fecal samples of patients with diarrhea with or without concomitant respiratory symptoms. A characteristic feature of HBoV studies is the high frequency of coinciding detections, or codetections, with other viruses. Available data nevertheless indicate a statistical association between HBoV and acute respiratory tract disease. We present a model incorporating these somewhat contradictory findings and suggest that primary HBoV infection causes respiratory tract symptoms which can be followed by prolonged low-level virus shedding in the respiratory tract. Detection of the virus in this phase will be facilitated by other infections, either simply via increased sample cell count or via reactivation of HBoV, leading to an increased detection frequency of HBoV during other virus infections. We conclude that the majority of available HBoV studies are limited by the sole use of PCR diagnostics on respiratory tract secretions, addressing virus prevalence but not disease association. The ability to detect primary infection through the development of improved diagnostic methods will be of great importance for future studies seeking to assign a role for HBoV in causing respiratory illnesses.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1128/cmr.00030-07

Cites

83 of 83 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

The neighbor-joining method: a new method for reconstructing phylogenetic trees.
Saitou, N., & Nei, M. (1987) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a040454 · Cited by 59,959
The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools
Thompson, J. (1997) · Nucleic Acids Research · doi:10.1093/nar/25.24.4876 · Cited by 38,685
Tree View: An application to display phylogenetic trees on personal computers
Page, R. (1996) · Computer applications in the biosciences · doi:10.1093/bioinformatics/12.4.357 · Cited by 10,223
How long do nosocomial pathogens persist on inanimate surfaces? A systematic review
Krämer, A., Schwebke, I., & Kampf, G. (2006) · BMC Infectious Diseases · doi:10.1186/1471-2334-6-130 · Cited by 2,508
Identification of a new human coronavirus
van der Hoek, L., Pyrć, K., Jebbink, M. F., Vermeulen-Oost, W., Berkhout, R. J. M., Wolthers, K. C., Dillen, P. M. E. W., Kaandorp, J. C., Spaargaren, J., & Berkhout, B. (2004) · Nature Medicine · doi:10.1038/nm1024 · Cited by 1,868
Cloning of a human parvovirus by molecular screening of respiratory tract samples
Allander, T., Tammi, M. T., Eriksson, M., Bjerkner, A., Tiveljung‐Lindell, A., & Andersson, B. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504666102 · Cited by 1,566
Self-citation
Characterization and Complete Genome Sequence of a Novel Coronavirus, Coronavirus HKU1, from Patients with Pneumonia
Woo, P. C. Y., Lau, S. K. P., Chu, C., Chan, K., Tsoi, H., Huang, Y. P., Wong, B. H. L., Poon, R. W., Cai, J. J., Luk, W., et al. (2004) · Journal of Virology · doi:10.1128/jvi.79.2.884-895.2005 · Cited by 1,525
Diagnosis and Management of Bronchiolitis
(2006) · PEDIATRICS · doi:10.1542/peds.2006-2223 · Cited by 1,055
Human Metapneumovirus and Lower Respiratory Tract Disease in Otherwise Healthy Infants and Children
Williams, J. V., Harris, P. A., Tollefson, S. J., Halburnt, L. L., Pingsterhaus, J. M., Edwards, K. M., Wright, P. F., & Crowe, J. E. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa025472 · Cited by 987
Sequence-based identification of microbial pathogens: a reconsideration of Koch's postulates
Fredericks, D. N., & Relman, D. A. (1996) · Clinical Microbiology Reviews · doi:10.1128/cmr.9.1.18 · Cited by 959

Show all 83 references

Research works printed but not linked: 1

Modrow, S., and B. Gärtner. 2006. Parvovirus B19 Infektionen in der Schwangerschaft. Dtsch. Árztebl.103:A2869-A2876.

Sorted by citations

Viral pneumonia
Ruuskanen, O., Lahti, E., Jennings, L., & Murdoch, D. R. (2011) · The Lancet · doi:10.1016/s0140-6736(10)61459-6 · Cited by 1,241
The airway epithelium: soldier in the fight against respiratory viruses
Vareille, M., Kieninger, E., Edwards, M. R., & Regamey, N. (2011) · Clinical Microbiology Reviews · doi:10.1128/cmr.00014-10 · Cited by 655
Human Parvoviruses
Qiu, J., Söderlund‐Venermo, M., & Young, N. S. (2016) · Clinical Microbiology Reviews · doi:10.1128/cmr.00040-16 · Cited by 436
Human Bocaviruses Are Highly Diverse, Dispersed, Recombination Prone, and Prevalent in Enteric Infections
Kapoor, A., Peter Simmonds, K., Slikas, B., Li, L., Bodhidatta, L., Sethabutr, O., Triki, H., Bahri, O., Oderinde, B. S., Baba, M., et al. (2010) · The Journal of Infectious Diseases · doi:10.1086/652416 · Cited by 380
Viral Infections of the Lower Respiratory Tract: Old Viruses, New Viruses, and the Role of Diagnosis
Pavia, A. T. (2011) · Clinical Infectious Diseases · doi:10.1093/cid/cir043 · Cited by 354
The Fecal Virome of Pigs on a High-Density Farm
Shan, T., Li, L., Peter Simmonds, K., Wang, C., Moeser, A. J., & Delwart, E. (2011) · Journal of Virology · doi:10.1128/jvi.05217-11 · Cited by 347
A Newly Identified Bocavirus Species in Human Stool
Kapoor, A., Slikas, B., Peter Simmonds, K., Chieochansin, T., Naeem, A., Shaukat, S., Alam, M. M., Sharif, S., Angez, M., Zaidi, S., et al. (2008) · The Journal of Infectious Diseases · doi:10.1086/595831 · Cited by 325
Human bocavirus—the first 5 years
Jartti, T. T., Hedman, K., Jartti, L., Ruuskanen, O., Allander, T., & Söderlund‐Venermo, M. (2011) · Reviews in Medical Virology · doi:10.1002/rmv.720 · Cited by 278
Self-citation
Viruses in community‐acquired pneumonia in children aged less than 3 years old: High rate of viral coinfection
Cilla, G., Oñate, E., Pérez‐Yarza, E. G., Montes, M., Vicente, D. A., & Pérez-Trallero, E. (2008) · Journal of Medical Virology · doi:10.1002/jmv.21271 · Cited by 276
Frequent and Prolonged Shedding of Bocavirus in Young Children Attending Daycare
Martin, E. T., Fairchok, M. P., Kuypers, J. M., Magaret, A., Zerr, D. M., Wald, A., & Englund, J. A. (2010) · The Journal of Infectious Diseases · doi:10.1086/652405 · Cited by 228
Clinical Assessment and Improved Diagnosis of Bocavirus-induced Wheezing in Children, Finland
Söderlund‐Venermo, M., Lahtinen, A., Jartti, T. T., Hedman, L., Kemppainen, K. M., Lehtinen, P., Allander, T., Ruuskanen, O., & Hedman, K. (2009) · Emerging infectious diseases · doi:10.3201/eid1509.090204 · Cited by 202
Self-citation
Viral Respiratory Pathogens and Lung Injury
Clementi, N., Ghosh, S., Santis, M. D., Castelli, M., Criscuolo, E., Zanoni, I., Clementi, M., & Mancini, N. (2021) · Clinical Microbiology Reviews · doi:10.1128/cmr.00103-20 · Cited by 202
Human bocavirus: Current knowledge and future challenges
Guido, M., Tumolo, M. R., Verri, T., Romano, A., Serio, F., Giorgi, M. D., Donno, A. D., Bagordo, F., & Zizza, A. (2016) · World Journal of Gastroenterology · doi:10.3748/wjg.v22.i39.8684 · Cited by 184
Establishment of a Reverse Genetics System for Studying Human Bocavirus in Human Airway Epithelia
Huang, Q., Deng, X., Yan, Z., Cheng, F., Luo, Y., Shen, W., Lei-Butters, D. C. M., Chen, A. Y., Li, Y., Tang, L., et al. (2012) · PLoS Pathogens · doi:10.1371/journal.ppat.1002899 · Cited by 166
Identification of New Respiratory Viruses in the New Millennium
Berry, M. J., Gamieldien, J., & Fielding, B. C. (2015) · Viruses · doi:10.3390/v7030996 · Cited by 163
Clinical Utility of PCR for Common Viruses in Acute Respiratory Illness
Rhedin, S., Lindstrand, A., Rotzén‐Östlund, M., Tolfvenstam, T., Öhrmalm, L., Rinder, M. R., Zweygberg‐Wirgart, B., Örtqvist, Å., Henriques‐Normark, B., Broliden, K., et al. (2014) · PEDIATRICS · doi:10.1542/peds.2013-3042 · Cited by 162
Aetiology of lower respiratory tract infection in adults in primary care: a prospective study in 11 European countries
Ieven, M. M., Coenen, S., Loens, K., Lammens, C., Coenjaerts, F. E. J., Vanderstraeten, A., Henriques‐Normark, B., Crook, D. W., Huygen, K., Butler, C., et al. (2018) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2018.02.004 · Cited by 162
Frequent Detection of Highly Diverse Variants of Cardiovirus , Cosavirus , Bocavirus , and Circovirus in Sewage Samples Collected in the United States
Blinkova, O., Rosario, K., Li, L., Kapoor, A., Slikas, B., Bernardin, F., Breitbart, M., & Delwart, E. (2009) · Journal of Clinical Microbiology · doi:10.1128/jcm.01062-09 · Cited by 155
Molecular Characterization of Infectious Clones of the Minute Virus of Canines Reveals Unique Features of Bocaviruses
Sun, Y., Chen, A. Y., Cheng, F., Guan, W., Johnson, F. B., & Qiu, J. (2009) · Journal of Virology · doi:10.1128/jvi.02569-08 · Cited by 153
Acute Diarrhea in West African Children: Diverse Enteric Viruses and a Novel Parvovirus Genus
Phan, T., Vo, N., Bonkoungou, I., Kapoor, A., Barro, N., O'Ryan, M., Kapusinszky, B., Wang, C.-L., & Delwart, E. (2012) · Journal of Virology · doi:10.1128/jvi.01427-12 · Cited by 137
Epidemiology of Multiple Respiratory Viruses in Childcare Attendees
Martin, E. T., Fairchok, M. P., Stednick, Z. J., Kuypers, J. M., & Englund, J. A. (2013) · The Journal of Infectious Diseases · doi:10.1093/infdis/jis934 · Cited by 138
Nearly Constant Shedding of Diverse Enteric Viruses by Two Healthy Infants
Kapusinszky, B., Minor, P., & Delwart, E. (2012) · Journal of Clinical Microbiology · doi:10.1128/jcm.01589-12 · Cited by 128
Impact of viral infections in children with community‐acquired pneumonia: results of a study of 17 respiratory viruses
Esposito, S., Daleno, C., Prunotto, G., Scala, A., Tagliabue, C., Borzani, I., Fossali, E. F., Pelucchi, C., & Principi, N. (2012) · Influenza and Other Respiratory Viruses · doi:10.1111/j.1750-2659.2012.00340.x · Cited by 135
Changing epidemiology of respiratory viral infections in hematopoietic cell transplant recipients and solid organ transplant recipients
Renaud, C., & Campbell, A. P. (2011) · Current Opinion in Infectious Diseases · doi:10.1097/qco.0b013e3283480440 · Cited by 135
The role of infections and coinfections with newly identified and emerging respiratory viruses in children
Debiaggi, M., Canducci, F., Ceresola, E. R., & Clementi, M. (2012) · Virology Journal · doi:10.1186/1743-422x-9-247 · Cited by 130
Disinfection efficacy against parvoviruses compared with reference viruses
Eterpi, M., McDonnell, G. E., & Thomas, V. (2009) · Journal of Hospital Infection · doi:10.1016/j.jhin.2009.05.016 · Cited by 130
Characterization of the gene expression profile of human bocavirus
Chen, A. Y., Cheng, F., Lou, S., Luo, Y., Liu, Z., Delwart, E., Pintel, D. J., & Qiu, J. (2010) · Virology · doi:10.1016/j.virol.2010.04.014 · Cited by 121
Identification and Characterization of a New Bocavirus Species in Gorillas
Kapoor, A., Mehta, N., Esper, F. P., Poljšak‐Prijatelj, M., Quan, P., Qaisar, N., Delwart, E., & Lipkin, W. I. (2010) · PLoS ONE · doi:10.1371/journal.pone.0011948 · Cited by 118
Induced sputum in the diagnosis of childhood community-acquired pneumonia
Lahti, E., Peltola, V. T., Waris, M. E., Virkki, R., Rantakokko‐Jalava, K., Jalava, J., Eerola, E., & Ruuskanen, O. (2008) · Thorax · doi:10.1136/thx.2008.099051 · Cited by 114
Single, dual and multiple respiratory virus infections and risk of hospitalization and mortality
Goka, E., Vallely, P. J., Mutton, K. J., & Klapper, P. E. (2014) · Epidemiology and Infection · doi:10.1017/s0950268814000302 · Cited by 111
Association of Human Bocavirus 1 Infection with Respiratory Disease in Childhood Follow-up Study, Finland
Meriluoto, M., Hedman, L., Tanner, L. M., Simell, V., Mäkinen, M., Simell, S., Mykkänen, J., Korpelainen, J., Ruuskanen, O., Ilonen, J., et al. (2012) · Emerging infectious diseases · doi:10.3201/eid1802.111293 · Cited by 111
Metagenomics and the development of viral water quality tools
Bibby, K. J., Crank, K. C., Greaves, J., Li, X., Wu, Z., Hamza, I. A., & Stachler, E. N. (2019) · npj Clean Water · doi:10.1038/s41545-019-0032-3 · Cited by 109
Viral Pathogen Detection by Metagenomics and Pan-Viral Group Polymerase Chain Reaction in Children With Pneumonia Lacking Identifiable Etiology
Schlaberg, R., Queen, K., Simmon, K. E., Tardif, K. D., Stockmann, C., Flygare, S., Kennedy, B. J., Voelkerding, K., Bramley, A., Zhang, J., et al. (2017) · Journal of Infectious Diseases · doi:10.1093/infdis/jix148 · Cited by 99
Respiratory Viruses
Boncristiani, H., Criado, M. F., & Arruda, E. (2009) · Elsevier eBooks · doi:10.1016/b978-012373944-5.00314-x · Cited by 112
Parvovirus B19
Landry, M. L. (2016) · Microbiology Spectrum · doi:10.1128/microbiolspec.dmih2-0008-2015 · Cited by 100
Detection of multiple respiratory pathogens during primary respiratory infection: nasal swab versus nasopharyngeal aspirate using real-time polymerase chain reaction
Meerhoff, T. J., Houben, M. L., Coenjaerts, F. E. J., Kimpen, J. L. L., Hofland, R. W., Schellevis, F., & Bont, L. (2010) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-009-0865-7 · Cited by 98
Serologically verified human bocavirus pneumonia in children
Don, M., Söderlund‐Venermo, M., Valent, F., Lahtinen, A., Hedman, L., Canciani, M. C., Hedman, K., & Korppi, M. O. (2009) · Pediatric Pulmonology · doi:10.1002/ppul.21151 · Cited by 96
The expanding range of parvoviruses which infect humans
Brown, K. E. (2010) · Reviews in Medical Virology · doi:10.1002/rmv.648 · Cited by 93
Widespread Infection with Homologues of Human Parvoviruses B19, PARV4, and Human Bocavirus of Chimpanzees and Gorillas in the Wild
Sharp, C., LeBreton, M., Kantola, K., Nana, A., Diffo, J. L. D., Djoko, C. F., Tamoufé, U., Kiyang, J., Tafon, B., Ngole, E. M., et al. (2010) · Journal of Virology · doi:10.1128/jvi.01304-10 · Cited by 85
Viral Co-Infections in Pediatric Patients Hospitalized with Lower Tract Acute Respiratory Infections
Cebey‐López, M., Herberg, J. A., Pardo‐Seco, J., Gómez‐Carballa, A., Martinón-Torres, N., Salas, A., Martinón‐Sánchez, J. M., Gormley, S., Sumner, E., Fink, C. G., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0136526 · Cited by 85
Respiratory Virus Infections of the Stem Cell Transplant Recipient and the Hematologic Malignancy Patient
Fontana, L., & Strasfeld, L. M. (2019) · Infectious Disease Clinics of North America · doi:10.1016/j.idc.2019.02.004 · Cited by 85
Systematic review and meta-analysis of the prevalence of common respiratory viruses in children < 2 years with bronchiolitis in the pre-COVID-19 pandemic era
Kenmoe, S., Kengne-Ndé, C., Ebogo‐Belobo, J. T., Mbaga, D. S., Modiyinji, A. F., & Njouom, R. (2020) · PLoS ONE · doi:10.1371/journal.pone.0242302 · Cited by 85
PCR for detection of respiratory viruses: seasonal variations of virus infections
Olofsson, S., Brittain-Long, R., Andersson, L. M., Westin, J., & Lindh, M. (2011) · Expert Review of Anti-infective Therapy · doi:10.1586/eri.11.75 · Cited by 83
Severe varicella-zoster virus pneumonia: a multicenter cohort study
Mirouse, A., Vignon, P., Piron, P., Robert, R., Papazian, L., Géri, G., Blanc, P., Guitton, C., Guérin, C., Bigé, N., et al. (2017) · Critical Care · doi:10.1186/s13054-017-1731-0 · Cited by 83
A Novel Chimeric Adenoassociated Virus 2/Human Bocavirus 1 Parvovirus Vector Efficiently Transduces Human Airway Epithelia
Yan, Z., Keiser, N. W., Song, Y., Deng, X., Cheng, F., Qiu, J., & Engelhardt, J. F. (2013) · Molecular Therapy · doi:10.1038/mt.2013.92 · Cited by 79
Human bocaviruses: Possible etiologic role in respiratory infection
Broccolo, F., Falcone, V., Esposito, S., & Toniolo, A. (2015) · Journal of Clinical Virology · doi:10.1016/j.jcv.2015.09.008 · Cited by 73
Life-Threatening Respiratory Tract Disease with Human Bocavirus-1 Infection in a 4-Year-Old Child
Edner, N., Rodas, P. C., Falk, L., Hedman, K., Söderlund‐Venermo, M., & Allander, T. (2011) · Journal of Clinical Microbiology · doi:10.1128/jcm.05706-11 · Cited by 72
Self-citation
Genomic Features of the Human Bocaviruses
Schildgen, O., Qiu, J., & Söderlund‐Venermo, M. (2011) · Future Virology · doi:10.2217/fvl.11.136 · Cited by 72
Self-citation
Detection of Head-to-Tail DNA Sequences of Human Bocavirus in Clinical Samples
Lüsebrink, J., Schildgen, V., Tillmann, R. L., Wittleben, F., Böhmer, A. C., Müller, A., & Schildgen, O. (2011) · PLoS ONE · doi:10.1371/journal.pone.0019457 · Cited by 69
Self-citation
Genetic variability of human metapneumovirus amongst an all ages population in Cambodia between 2007 and 2009
Arnott, A., Vong, S., Mardy, S., Naughtin, M., Beauté, J., Rith, S., Guillard, B., Deubel, V., & Buchy, P. (2011) · Infection Genetics and Evolution · doi:10.1016/j.meegid.2011.01.016 · Cited by 68
Respiratory Virus Infections in Hematopoietic Cell Transplant Recipients
Pochon, C., & Voigt, S. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.03294 · Cited by 67
Dating of human bocavirus infection with protein-denaturing IgG-avidity assays—Secondary immune activations are ubiquitous in immunocompetent adults
Hedman, L., Söderlund‐Venermo, M., Jartti, T. T., Ruuskanen, O., & Hedman, K. (2010) · Journal of Clinical Virology · doi:10.1016/j.jcv.2010.02.003 · Cited by 66
Bocavirus Infection Induces a DNA Damage Response That Facilitates Viral DNA Replication and Mediates Cell Death
Luo, Y., Chen, A. Y., & Qiu, J. (2010) · Journal of Virology · doi:10.1128/jvi.01534-10 · Cited by 66
The Relationship Between Respiratory Viral Loads and Diagnosis in Children Presenting to a Pediatric Hospital Emergency Department
Utokaparch, S., Marchant, D., Gosselink, J. V., McDonough, J. E., Thomas, É., Hogg, J. C., & Hegele, R. G. (2010) · The Pediatric Infectious Disease Journal · doi:10.1097/inf.0b013e3181ff2fac · Cited by 66
Does Viral Co-Infection Influence the Severity of Acute Respiratory Infection in Children?
Cebey‐López, M., Herberg, J. A., Pardo‐Seco, J., Gómez‐Carballa, A., Martinón-Torres, N., Salas, A., Martinón‐Sánchez, J. M., Justicia-Grande, A. J., Calle, I. R., Sumner, E., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0152481 · Cited by 66
Respiratory RNA Viruses
Hodinka, R. L. (2016) · Microbiology Spectrum · doi:10.1128/microbiolspec.dmih2-0028-2016 · Cited by 64
Epidemiology of human respiratory viruses in children with acute respiratory tract infection in a 3-year hospital-based survey in Northern Italy
Conto, F. D., Conversano, F., Medici, M. C., Ferraglia, F., Pinardi, F., Arcangeletti, C., Chezzi, C., & Calderaro, A. (2019) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2019.01.008 · Cited by 65
Human Bocavirus: Lessons Learned to Date
Schildgen, O. (2013) · Pathogens · doi:10.3390/pathogens2010001 · Cited by 63
Self-citation
Severe Human Bocavirus Infection, Germany
Körner, R. W., Söderlund‐Venermo, M., Koningsbruggen-Rietschel, S. V., Kaiser, R., Malecki, M., & Schildgen, O. (2011) · Emerging infectious diseases · doi:10.3201/eid1712.110574 · Cited by 63
Self-citation
A novel multiplex real-time RT-PCR assay with FRET hybridization probes for the detection and quantitation of 13 respiratory viruses
Lassaunière, R., Kresfelder, T., & Venter, M. (2010) · Journal of Virological Methods · doi:10.1016/j.jviromet.2010.02.005 · Cited by 62
The impact of respiratory viruses on lung health after preterm birth
Townsi, N., Laing, I. A., Hall, G. L., & Simpson, S. J. (2018) · European Clinical Respiratory Journal · doi:10.1080/20018525.2018.1487214 · Cited by 60
Human bocavirus 1 infects commercially available primary human airway epithelium cultures productively
Deng, X., Li, Y., & Qiu, J. (2013) · Journal of Virological Methods · doi:10.1016/j.jviromet.2013.10.012 · Cited by 61
High Viral Load of Human Bocavirus Correlates with Duration of Wheezing in Children with Severe Lower Respiratory Tract Infection
Deng, Y., Gu, X.-Y., Zhao, X., Luo, J., Luo, Z., Wang, L., Fu, Z., Yang, X., & Liu, E. (2012) · PLoS ONE · doi:10.1371/journal.pone.0034353 · Cited by 61
The Human Bocavirus Is Associated with Some Lung and Colorectal Cancers and Persists in Solid Tumors
Schildgen, V., Malecki, M., Tillmann, R. L., Brockmann, M. J., & Schildgen, O. (2013) · PLoS ONE · doi:10.1371/journal.pone.0068020 · Cited by 61
Self-citation
Detection of human bocavirus and human metapneumovirus by real-time PCR from patients with respiratory symptoms in Southern Brazil
Pilger, D. A., Cantarelli, V. V., Amantéa, S. L., & Leistner‐Segal, S. (2011) · Memórias do Instituto Oswaldo Cruz · doi:10.1590/s0074-02762011000100009 · Cited by 59
Viruses Associated With Pneumonia in Adults
Cesario, T. C. (2012) · Clinical Infectious Diseases · doi:10.1093/cid/cis297 · Cited by 60
Rare and Emerging Viral Infections in Transplant Recipients
Waggoner, J. J., Soda, E. A., & Deresinski, S. C. (2013) · Clinical Infectious Diseases · doi:10.1093/cid/cit456 · Cited by 57
Human bocavirus infection diagnosed serologically among children admitted to hospital with community‐acquired pneumonia in a tropical region
Nascimento-Carvalho, C. M., Cardoso, M. R. A., Meriluoto, M., Kemppainen, K. M., Kantola, K., Ruuskanen, O., Hedman, K., & Söderlund‐Venermo, M. (2011) · Journal of Medical Virology · doi:10.1002/jmv.22268 · Cited by 56
Pneumonia in the developed world
Prayle, A., Atkinson, M., & Smyth, A. R. (2010) · Paediatric Respiratory Reviews · doi:10.1016/j.prrv.2010.09.012 · Cited by 55
Novel canine bocavirus strain associated with severe enteritis in a dog litter
Bodewes, R., Lapp, S., Hahn, K., Habierski, A., Förster, C., König, M., Wohlsein, P., Osterhaus, A., & Baumgärtner, W. (2014) · Veterinary Microbiology · doi:10.1016/j.vetmic.2014.08.025 · Cited by 56
Detection of Human Bocavirus mRNA in Respiratory Secretions Correlates with High Viral Load and Concurrent Diarrhea
Proença‐Módena, J. L., Gagliardi, T. B., de Paula, F. E., Iwamoto, M. A., Criado, M. F., Câmara, A. A., Acrani, G. O., Cintra, O. A. L., Cervi, M. C., Arruda, L. K., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0021083 · Cited by 53
Pitfalls in interpretation of CT-values of RT-PCR in children with acute respiratory tract infections
Wishaupt, J. O., van der Ploeg, T., Smeets, L. C., de Groot, R., Versteegh, F. G. A., & Hartwig, N. G. (2017) · Journal of Clinical Virology · doi:10.1016/j.jcv.2017.02.010 · Cited by 53
Structural Insights into Human Bocaparvoviruses
Mietzsch, M., Kailasan, S., Garrison, J., Ilyas, M., Chipman, P. R., Kantola, K., Janssen, M. E. W., Spear, J. M., Sousa, D. R., McKENNA, R. V., et al. (2017) · Journal of Virology · doi:10.1128/jvi.00261-17 · Cited by 53
Human Bocavirus in Childhood: A True Respiratory Pathogen or a “Passenger” Virus? A Comprehensive Review
Trapani, S., Caporizzi, A., Ricci, S., & Indolfi, G. (2023) · Microorganisms · doi:10.3390/microorganisms11051243 · Cited by 51
Clinical significance of different virus load of human bocavirus in patients with lower respiratory tract infection
Jiang, W., Yin, F., Zhou, W., Yan, Y., & Ji, W. (2016) · Scientific Reports · doi:10.1038/srep20246 · Cited by 51
Canine Bocavirus Type 2 Infection Associated With Intestinal Lesions
Piewbang, C., Jo, W. K., Puff, C., Ludlow, M., van der Vries, E., Banlunara, W., Rungsipipat, A., Kruppa, J., Jung, K., Techangamsuwan, S., et al. (2018) · Veterinary Pathology · doi:10.1177/0300985818755253 · Cited by 50
Bocavirus Infection Induces Mitochondrion-Mediated Apoptosis and Cell Cycle Arrest at G2/M Phase
Chen, A. Y., Luo, Y., Cheng, F., Sun, Y., & Qiu, J. (2010) · Journal of Virology · doi:10.1128/jvi.02094-09 · Cited by 49
Beyond Respiratory Syncytial Virus and Rhinovirus in the Pathogenesis and Exacerbation of Asthma
Coverstone, A. M., Wang, L., & Sumino, K. (2019) · Immunology and Allergy Clinics of North America · doi:10.1016/j.iac.2019.03.007 · Cited by 50
PCR Improves Diagnostic Yield from Lung Aspiration in Malawian Children with Radiologically Confirmed Pneumonia
Carrol, E. D., Mankhambo, L., Guiver, M., Banda, D. L., The IPD Study Group, Denis, B., Dove, W., Jeffers, G., MOLYNEUX, E. M., Molyneux, M. E., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0021042 · Cited by 47
Distinctive clinical features of human bocavirus in children younger than 2 years
Moriyama, Y., Hamada, H., Okada, M., Tsuchiya, N., Maru, H., Shirato, Y., Maeda, Y., Hirose, Y., Yoshida, M., Omura, Y., et al. (2010) · European Journal of Pediatrics · doi:10.1007/s00431-010-1183-x · Cited by 47
Comparative Diagnosis of Human Bocavirus 1 Respiratory Infection With Messenger RNA Reverse-Transcription Polymerase Chain Reaction (PCR), DNA Quantitative PCR, and Serology
Xu, M., Arku, B., Jartti, T. T., Koskinen, J. O., Peltola, V. T., Hedman, K., & Söderlund‐Venermo, M. (2017) · The Journal of Infectious Diseases · doi:10.1093/infdis/jix169 · Cited by 47
Evidence of human bocavirus circulating in children and adults, Cleveland, Ohio
Chow, B. D. W., Huang, Y. T., & Esper, F. P. (2008) · Journal of Clinical Virology · doi:10.1016/j.jcv.2008.07.009 · Cited by 44
Emerging and Reemerging Infectious Disease Threats
KHABBAZ, R. F., Bell, B. P., Schuchat, A., Ostroff, S. M., Moseley, R. R., Levitt, A. M., & Hughes, J. M. (2015) · Elsevier eBooks · doi:10.1016/b978-1-4557-4801-3.00014-x · Cited by 46
Prevalence of human bocavirus infections in Europe. A systematic review and meta‐analysis
Polo, D., Lema, A., Gándara, E., & Romalde, J. L. (2021) · Transboundary and Emerging Diseases · doi:10.1111/tbed.14233 · Cited by 44
Utilization of Nucleic Acid Amplification Assays for the Detection of Respiratory Viruses
Kehl, S. C., & Kumar, S. (2009) · Clinics in Laboratory Medicine · doi:10.1016/j.cll.2009.07.008 · Cited by 42
Discovery and Genomic Characterization of a Novel Ovine Partetravirus and a New Genotype of Bovine Partetravirus
Tse, H., Tsoi, H., Teng, J. L. L., Chen, X., Liu, H., Zhou, B., Zheng, B., Woo, P. C. Y., Lau, S. K. P., & Yuen, K. (2011) · PLoS ONE · doi:10.1371/journal.pone.0025619 · Cited by 42
Novel application for isothermal nucleic acid sequence-based amplification (NASBA)
Böhmer, A. C., Schildgen, V., Lüsebrink, J., Ziegler, S. M., Tillmann, R. L., Kleines, M., & Schildgen, O. (2009) · Journal of Virological Methods · doi:10.1016/j.jviromet.2009.02.010 · Cited by 41
Self-citation
The nonstructural protein NP1 of human bocavirus 1 induces cell cycle arrest and apoptosis in Hela cells
Sun, B., Cai, Y., Li, Y., Li, J., Liu, K., Li, Y., & Yang, Y. (2013) · Virology · doi:10.1016/j.virol.2013.02.013 · Cited by 41
Analysis of cis and trans Requirements for DNA Replication at the Right-End Hairpin of the Human Bocavirus 1 Genome
Shen, W., Deng, X., Zou, W., Engelhardt, J. F., Yan, Z., & Qiu, J. (2016) · Journal of Virology · doi:10.1128/jvi.00708-16 · Cited by 41
Molecular epidemiology of influenza, RSV, and other respiratory infections among children in Qatar: A six years report (2012–2017)
Al‐Romaihi, H. E., Smatti, M. K., Al-Khatib, H. A., Coyle, P. V., Ganesan, N., Nadeem, S., Farag, E., Thani, A. A. A., Al‐Khal, A., Ansari, K., et al. (2020) · International Journal of Infectious Diseases · doi:10.1016/j.ijid.2020.04.008 · Cited by 41
Etiology of Acute Respiratory Infections in Infants
Kumar, P., Medigeshi, G. R., Mishra, V. S., Islam, M., Randev, S., Mukherjee, A., Chaudhry, R., Kapil, A., Jat, K. R., Lodha, R., et al. (2016) · The Pediatric Infectious Disease Journal · doi:10.1097/inf.0000000000001359 · Cited by 40
DNA Damage Signaling Is Required for Replication of Human Bocavirus 1 DNA in Dividing HEK293 Cells
Deng, X., Xu, P., Zou, W., Shen, W., Peng, J., Liu, K., Engelhardt, J. F., Yan, Z., & Qiu, J. (2016) · Journal of Virology · doi:10.1128/jvi.01831-16 · Cited by 40
QUANTITATION OF RESPIRATORY VIRUSES IN RELATION TO CLINICAL COURSE IN CHILDREN WITH ACUTE RESPIRATORY TRACT INFECTIONS
Jansen, R. R., Schinkel, J., Dek, I., Koekkoek, S. M., Visser, C. E., de Jong, M. D., Molenkamp, R., & Pajkrt, D. (2009) · The Pediatric Infectious Disease Journal · doi:10.1097/inf.0b013e3181b6de8a · Cited by 39
Detection and genetic characterization of feline bocavirus in Northeast China
Yi, S., Niu, J., Wang, H., Dong, G., Zhao, Y., Dong, H., Guo, Y., Wang, K., & Hu, G. (2018) · Virology Journal · doi:10.1186/s12985-018-1034-3 · Cited by 39
Original antigenic sin with human bocaviruses 1–4
Li, X., Kantola, K., Hedman, L., Arku, B., Hedman, K., & Söderlund‐Venermo, M. (2015) · Journal of General Virology · doi:10.1099/jgv.0.000253 · Cited by 38
Absence of Detectable Replication of Human Bocavirus Species 2 in Respiratory Tract
Chieochansin, T., Kapoor, A., Delwart, E., Poovorawan, Y., & Peter Simmonds, K. (2009) · Emerging infectious diseases · doi:10.3201/eid1509.090394 · Cited by 38
Epidemiologic and Clinical Characteristics of Coronavirus and Bocavirus Respiratory Infections after Allogeneic Stem Cell Transplantation: A Prospective Single-Center Study
Piñana, J. L., Madrid, S., Pérez, A., Hernández‐Boluda, J. C., Giménez, E., Terol, M. J., Calabuig, M., Navarro, D., & Solano, C. (2017) · Transplantation and Cellular Therapy · doi:10.1016/j.bbmt.2017.11.001 · Cited by 38
Bacterial tracheitis: A multi-centre perspective
Tebruegge, M., Pantazidou, A., Thorburn, K., Riordan, A. I., Round, J. E. C., Munter, C. D., Walters, S., & Curtis, N. C. (2009) · Scandinavian Journal of Infectious Diseases · doi:10.1080/00365540902913478 · Cited by 38
‘Human bocavirus in Pakistani children with gastroenteritis'
Alam, M. M., Khurshid, A., Shaukat, S., Sharif, S., Rana, M. S., Angez, M., Nisar, N., Aamir, U. B., Naeem, M., & Zaidi, S. S. Z. (2015) · Journal of Medical Virology · doi:10.1002/jmv.24090 · Cited by 37
The 2009 pandemic influenza A(H1N1) coincides with changes in the epidemiology of other viral pathogens causing acute respiratory tract infections in children
Gröndahl, B., Ankermann, T., von Bismarck, P., Rockahr, S., Kowalzik, F., Gehring, S., Meyer, C. U., Knuf, M., & Puppe, W. (2013) · Infection · doi:10.1007/s15010-013-0545-5 · Cited by 37

Authors: Schildgen, O., Müller, A., Allander, T., Mackay, I. M., Völz, S., Kupfer, B., & Simon, A.
Affiliations: Royal Children's Hospital (AU)
Institute for Virology, University of Bonn, Bonn, Germany
ORCID: Schildgen, Oliver
Mackay, Ian M.
Simon, Arne
Venue: Clinical Microbiology Reviews
Publisher: American Society for Microbiology
Published: 2008-04
Volume: 21
Issue: 2
Pages: 291-304
ISSN: 0893-8512 (ISSN-L)
1098-6618
DOI: 10.1128/cmr.00030-07
PMC: PMC2292574
OpenAlex: W2106395530
Cited by: 300
References: 83
Citations by year: 2026: 3 · 2025: 6 · 2024: 6 · 2023: 11 · 2022: 10 · 2021: 12 · 2020: 10 · 2019: 10 · 2018: 15 · 2017: 12 · 2016: 21 · 2015: 22 · 2014: 14 · 2013: 20 · 2012: 19
FWCI: 3.88
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: journals.asm.org/non-commercial-tdm-license (tdm)
Locations: Clinical Microbiology Reviews (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Epidemiology › Respiratory viral infections research
Health Sciences › Medicine › Infectious Diseases › Viral Infections and Immunology Research
Health Sciences › Medicine › Infectious Diseases › Parvovirus B19 Infection Studies
Keywords: human bocavirus, acute respiratory infections, Parvoviridae, bocavirus, viral co-detection, viral reactivation, infants and young children, respiratory secretions, viral prevalence, primary infection
MeSH terms: Antigens, Viral, Humans, Parvoviridae Infections, Respiratory System, Respiratory Tract Infections, Bocavirus

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Human Bocavirus: Passenger or Pathogen in Acute Respiratory Tract Infections?

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks