Cited by 2,526Helicobacter pylori-related gastroenterology studiesGastrointestinal motility and disordersSalmonella and Campylobacter epidemiology

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Pathogenesis of Helicobacter pylori Infection

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Kusters, Johannes G., van Vliet, Arnoud H. M., Kuipers, Ernst J.·2006·Clinical Microbiology Reviews

DOI 10.1128/cmr.00054-05PMC PMC1539101

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Abstract

SUMMARY: Helicobacter pylori is the first formally recognized bacterial carcinogen and is one of the most successful human pathogens, as over half of the world's population is colonized with this gram-negative bacterium. Unless treated, colonization usually persists lifelong. H. pylori infection represents a key factor in the etiology of various gastrointestinal diseases, ranging from chronic active gastritis without clinical symptoms to peptic ulceration, gastric adenocarcinoma, and gastric mucosa-associated lymphoid tissue lymphoma. Disease outcome is the result of the complex interplay between the host and the bacterium. Host immune gene polymorphisms and gastric acid secretion largely determine the bacterium's ability to colonize a specific gastric niche. Bacterial virulence factors such as the cytotoxin-associated gene pathogenicity island-encoded protein CagA and the vacuolating cytotoxin VacA aid in this colonization of the gastric mucosa and subsequently seem to modulate the host's immune system. This review focuses on the microbiological, clinical, immunological, and biochemical aspects of the pathogenesis of H. pylori .

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Items 401–600 of 732

The Nickel-Responsive Regulator NikR Controls Activation and Repression of Gene Transcription inHelicobacter pylori
Ernst, F. D., Kuipers, E. J., Heijens, A., Sarwari, R., Stoof, J., Penn, C. W., Kusters, J. G., & van Vliet, A. H. M. (2005) · Infection and Immunity · doi:10.1128/iai.73.11.7252-7258.2005 · Cited by 101
Self-citation
Pathogens use carbohydrates to escape immunity induced by dendritic cells
van Kooyk, Y., Engering, A. J., Lekkerkerker, A., Ludwig, I. S., & Geijtenbeek, T. B. H. (2004) · Current Opinion in Immunology · doi:10.1016/j.coi.2004.05.010 · Cited by 100
Helicobacter pylori infection produces reversible glycosylation changes to gastric mucins
Ota, H., Nakayama, J., Momose, M., et al. (1998) · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · doi:10.1007/s004280050269 · Cited by 100
Nickel binding and immunological properties of the C‐terminal domain of the Helicobacter pylori GroES homologue (HspA)
Kansau, I., Guillain, F., Thiberge, J., et al. (1996) · Molecular Microbiology · doi:10.1046/j.1365-2958.1996.01536.x · Cited by 100
NikR-mediated regulation of Helicobacter pylori acid adaptation
van Vliet, A. H. M., Ernst, F. D., & Kusters, J. G. (2004) · Trends in Microbiology · doi:10.1016/j.tim.2004.09.005 · Cited by 100
Self-citation
The Importance of Urease in Acid Protection for the Gastric-colonising BacteriaHelicobacter pyloriandHelicobacter felissp. nov
Ferrero, R. L., & Lee, A. (1991) · Microbial Ecology in Health and Disease · doi:10.3109/08910609109140133 · Cited by 100
Innate immune recognition of the extracellular mucosal pathogen, Helicobacter pylori
Ferrero, R. L. (2005) · Molecular Immunology · doi:10.1016/j.molimm.2004.12.001 · Cited by 98
Identification and characterization of an aliphatic amidase in Helicobacter pylori
Skouloubris, S., Labigne-Roussel, A., & Reuse, H. D. (1997) · Molecular Microbiology · doi:10.1111/j.1365-2958.1997.mmi536.x · Cited by 97
Protective Anti‐HelicobacterImmunity Is Induced with Aluminum Hydroxide or Complete Freund's Adjuvant by Systemic Immunization
Gottwein, J. M., Blanchard, T. G., Targoni, O. S., et al. (2001) · The Journal of Infectious Diseases · doi:10.1086/322032 · Cited by 97
Helicobacter pylori ribBA -Mediated Riboflavin Production Is Involved in Iron Acquisition
Worst, D. J., Gerrits, M. M., Vandenbroucke‐Grauls, C. M. J. E., & Kusters, J. G. (1998) · Journal of Bacteriology · doi:10.1128/jb.180.6.1473-1479.1998 · Cited by 97
Self-citation
Differential Regulation of Amidase- and Formamidase-mediated Ammonia Production by the Helicobacter pylori Fur Repressor
van Vliet, A. H. M., Stoof, J., Poppelaars, S. W., Bereswill, S., Homuth, G., Kist, M., Kuipers, E. J., & Kusters, J. G. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m207542200 · Cited by 97
Self-citation
Gastric B‐cell mucosa‐associated lymphoid tissue (MALT) lymphoma in an animal model of ‘Helicobacter heilmannii’ infection
O'Rourke, J., Dixon, M. F., JACK, A. S., et al. (2004) · The Journal of Pathology · doi:10.1002/path.1593 · Cited by 96
Genetic and Transmission Analysis ofHelicobacter pyloriStrains within a Family1
Raymond, J., Thiberge, J.-M., Chevalier, C., Kalach, N., Bergeret, M., Labigne-Roussel, A., & Dauga, C. (2004) · Emerging infectious diseases · doi:10.3201/eid1010.040042 · Cited by 96
Animal models of Helicobacter pylori infection and disease
O’Rourke, J., & Lee, A. V. (2003) · Microbes and Infection · doi:10.1016/s1286-4579(03)00123-0 · Cited by 95
The physiology and metabolism of Campylobacter jejuni and Helicobacter pylori
Kelly, D. J. (2001) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.2001.01350.x · Cited by 95
Helicobacter pylori Growth and Urease Detection in the Chemically Defined Medium Ham's F-12 Nutrient Mixture
Testerman, T. L., McGee, D. J., & Mobley, H. L. T. (2001) · Journal of Clinical Microbiology · doi:10.1128/jcm.39.11.3842-3850.2001 · Cited by 95
Contribution of the Helicobacter pylori Thiol Peroxidase Bacterioferritin Comigratory Protein to Oxidative Stress Resistance and Host Colonization
Wang, G., Olczak, A. A., Walton, J. P., & Maier, R. J. (2004) · Infection and Immunity · doi:10.1128/iai.73.1.378-384.2005 · Cited by 95
Mast Cells Are Critical Mediators of Vaccine-Induced Helicobacter Clearance in the Mouse Model
Velin, D., Bachmann, D., Bouzourène, H., & Michetti, P. (2005) · Gastroenterology · doi:10.1053/j.gastro.2005.04.010 · Cited by 95
Induction of ulceration and severe gastritis in Mongolian gerbil by Helicobacter pylori infection
Matsumoto, S., Washizuka, Y., Matsumoto, Y., et al. (1997) · Journal of Medical Microbiology · doi:10.1099/00222615-46-5-391 · Cited by 94
Discrimination between Cases of Duodenal Ulcer and Gastritis on the Basis of Putative Virulence Factors of Helicobacter pylori
Yamaoka, Y., Souchek, J., Odenbreit, S., Haas, R., Arnqvist, A., Borén, T., Kodama, T., Osato, M. S., Gutiérrez, Ó., Kim, J. G., et al. (2002) · Journal of Clinical Microbiology · doi:10.1128/jcm.40.6.2244-2246.2002 · Cited by 94
Acid‐induced expression of an LPS‐associated gene in Helicobacter pylori
McGowan, C. C., Necheva, A. S., Thompson, S. A., Cover, T. L., & Blaser, M. J. (1998) · Molecular Microbiology · doi:10.1046/j.1365-2958.1998.t01-1-01079.x · Cited by 93
Detection of Helicobacter pylori DNA in human faeces and water with different levels of faecal pollution in the north-east of Spain
Queralt, N., Bartolomé, R. M., & Araujo, R. (2005) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2004.02523.x · Cited by 93
Identification of surface-exposed outer membrane antigens of Helicobacter pylori
Doig, P. C., & Trevor J. TRUST (1994) · Infection and Immunity · doi:10.1128/iai.62.10.4526-4533.1994 · Cited by 93
Recurrent symptoms and gastro‐oesophageal reflux disease in patients with duodenal ulcer treated for Helicobacter pylori infection
Vakil, Hahn, & McSorley (2000) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2000.00677.x · Cited by 92
Human NK1 and NK2 subsets determined by purification of IFN-γ-secreting and IFN-γ-nonsecreting NK cells
Deniz, G., Akdiş, M., Aktas, E., Blaser, K., & Akdiş, C. A. (2002) · European Journal of Immunology · doi:10.1002/1521-4141(200203)32:3 · Cited by 92
The Acid Activation ofHelicobacter pyloriToxin VacA: Structural and Membrane Binding Studies
Molinari, M., Galli, C., de Bernard, M., et al. (1998) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1998.8808 · Cited by 92
Helicobacter mustelae -associated Gastric Adenocarcinoma in Ferrets ( Mustela putorius furo )
Fox, J. G., Dangler, C. A., Sager, W., et al. (1997) · Veterinary Pathology · doi:10.1177/030098589703400308 · Cited by 92
Virulence of Coccoid and Bacillary Forms of Helicobacter pylori in Gnotobiotic Piglets
Eaton, K. A., Catrenich, C. E., Makin, K. M., et al. (1995) · The Journal of Infectious Diseases · doi:10.1093/infdis/171.2.459 · Cited by 92
Modulation of Innate Cytokine Responses by Products of Helicobacter pylori
Meyer, F. P., Wilson, K. T., & James, S. P. (2000) · Infection and Immunity · doi:10.1128/iai.68.11.6265-6272.2000 · Cited by 92
Chronic active gastritis due to Helicobacter pylori in immunized gnotobiotic piglets
Eaton, K. A., & Krakowka, S. G. (1992) · Gastroenterology · doi:10.1016/0016-5085(92)91181-3 · Cited by 90
Effect of CD14 promoter polymorphism andH. pyloriinfection and its clinical outcomes on circulating CD14
Karhukorpi, J. M., Yan, Y., Niemelä, S., et al. (2002) · Clinical & Experimental Immunology · doi:10.1046/j.1365-2249.2002.01837.x · Cited by 90
Helicobacter pylori Lipopolysaccharide Binds to CD14 and Stimulates Release of Interleukin-8, Epithelial Neutrophil-Activating Peptide 78, and Monocyte Chemotactic Protein 1 by Human Monocytes
Bliss, C. M., Golenbock, D. T., Keates, S. E., Linevsky, J. K., & Kelly, C. P. (1998) · Infection and Immunity · doi:10.1128/iai.66.11.5357-5363.1998 · Cited by 90
Methionine sulphoxide reductase is an important antioxidant enzyme in the gastric pathogen Helicobacter pylori
Alamuri, P., & Maier, R. J. (2004) · Molecular Microbiology · doi:10.1111/j.1365-2958.2004.04190.x · Cited by 90
Identification of Loci Essential for the Growth ofHelicobacter pyloriunder Acidic Conditions
Bijlsma, J. J. E., Lie‐A‐Ling, M., Nootenboom, I. C., Vandenbroucke‐Grauls, C. M. J. E., & Kusters, J. G. (2000) · The Journal of Infectious Diseases · doi:10.1086/315855 · Cited by 90
Self-citation
Non-human reservoirs of Helicobacter pylori.
Fox, J. G. (1995) · PubMed · Cited by 89
Polymorphisms of Helicobacter pylori HP0638 Reflect Geographic Origin and Correlate with cagA Status
Ando, T., Peek, R. M., Pride, D. T., Levine, S. M., Takata, T., Lee, Y.-Y., Kusugami, K., ENDE, A. V. D., Kuipers, E. J., Kusters, J. G., et al. (2002) · Journal of Clinical Microbiology · doi:10.1128/jcm.40.1.239-246.2002 · Cited by 89
Self-citation
A flagellar sheath protein of Helicobacter pylori is identical to HpaA, a putative N-acetylneuraminyllactose-binding hemagglutinin, but is not an adhesin for AGS cells
Jones, A. C., Logan, R. P., Foynes, S., Cockayne, A., Wren, B. W., & Penn, C. W. (1997) · Journal of Bacteriology · doi:10.1128/jb.179.17.5643-5647.1997 · Cited by 88
Membrane channel structure of Helicobacter pylori vacuolating toxin: Role of multiple GXXXG motifs in cylindrical channels
Kim, S., Chamberlain, A. K., & Bowie, J. U. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308694101 · Cited by 88
Helicobacter pyloriInduces Interleukin-8 Secretion by Toll-Like Receptor 2- and Toll-Like Receptor 5-Dependent and -Independent Pathways
Torok, A. M., Bouton, A. H., & Goldberg, J. B. (2005) · Infection and Immunity · doi:10.1128/iai.73.3.1523-1531.2005 · Cited by 88
Helicobacter mustelae-associated gastric MALT lymphoma in ferrets.
Erdman, S. E., Corréa, P., Coleman, L. A., et al. (1997) · PubMed · Cited by 87
The Helicobacter pylori 19.6-kilodalton protein is an iron-containing protein resembling ferritin
Doig, P. C., Austin, J. W., & Trevor J. TRUST (1993) · Journal of Bacteriology · doi:10.1128/jb.175.2.557-560.1993 · Cited by 87
A revised annotation and comparative analysis of Helicobacter pylori genomes
Boneca, I. G. (2003) · Nucleic Acids Research · doi:10.1093/nar/gkg250 · Cited by 87
Acute gastritis associated with spiral organisms from cats
Lavelle, J. P., LANDAS, S. K., Mitros, F. A., et al. (1994) · Digestive Diseases and Sciences · doi:10.1007/bf02087417 · Cited by 87
Identification of the N-acetylneuraminyllactose-specific laminin-binding protein of Helicobacter pylori
Valkonen, K. H., Wadström, T., & Moran, A. P. (1997) · Infection and Immunity · doi:10.1128/iai.65.3.916-923.1997 · Cited by 87
ChronicHelicobacter pyloriInfection with Sydney Strain 1 and a Newly Identified Mouse-Adapted Strain (Sydney Strain 2000) in C57BL/6 and BALB/c Mice
Thompson, L. J., Danon, S. J., Wilson, J. E., O’Rourke, J., Salama, N. R., Falkow, S., Mitchell, H. M., & Lee, A. (2004) · Infection and Immunity · doi:10.1128/iai.72.8.4668-4679.2004 · Cited by 87
Temporal trends and geographical variations of peptic ulcer disease.
Sonnenberg, A. (1995) · PubMed · Cited by 87
motility
O’Toole, P. W., Lane, M. C., & Porwollik, S. (2000) · Microbes and Infection · doi:10.1016/s1286-4579(00)01274-0 · Cited by 86
Effects of omeprazole on intragastric pH and plasma gastrin are dependent on the CYP2C19 polymorphism
Sagar, M., Tybring, G., Dahl, M., et al. (2000) · Gastroenterology · doi:10.1053/gast.2000.16515 · Cited by 86
Toll-like receptor 4 regulates gastric pit cell responses to Helicobacter pylori infection.
Kawahara, T., Kuwano, Y., Teshima-Kondo, S., Kawai, T., Nikawa, T., Kishi, K., & Rokutan, K. (2001) · PubMed · Cited by 86
Helicobacter pylori and Extragastric Diseases – Other Helicobacters
Nilsson, H., Pietroiusti, A., Gabrielli, M., et al. (2005) · Helicobacter · doi:10.1111/j.1523-5378.2005.00334.x · Cited by 86
Transient and PersistentHelicobacter pyloriColonization in Native American Children
Pérez-Pérez, G. I., Sack, R. B., Reid, R., et al. (2003) · Journal of Clinical Microbiology · doi:10.1128/jcm.41.6.2401-2407.2003 · Cited by 86
Paracrystalline inclusions of a novel ferritin containing nonheme iron, produced by the human gastric pathogen Helicobacter pylori: evidence for a third class of ferritins
Frazier, B. A., Pfeifer, J. D., Russell, D. G., Falk, P., Olsén, A., Hammar, M., Westblom, T. U., & Normark, S. J. (1993) · Journal of Bacteriology · doi:10.1128/jb.175.4.966-972.1993 · Cited by 85
Distribution of Open Reading Frames of Plasticity Region of Strain J99 in Helicobacter pylori Strains Isolated from Gastric Carcinoma and Gastritis Patients in Costa Rica
Occhialini, A., Marais, A., Alm, R. A., García, F. T., Sierra, R., & Mégraud, F. (2000) · Infection and Immunity · doi:10.1128/iai.68.11.6240-6249.2000 · Cited by 85
The Helicobacter pylori CagA protein induces tyrosine dephosphorylation of ezrin
Selbach, M., Moese, S., Backert, S., Jungblut, P. R., & Meyer, T. F. (2004) · PROTEOMICS · doi:10.1002/pmic.200400915 · Cited by 85
High prevalence of Helicobacter pylori infection in cohabiting children. Epidemiology of a cluster, with special emphasis on molecular typing.
Vincent, P., Gottrand, F., Pernes, P., et al. (1994) · Gut · doi:10.1136/gut.35.3.313 · Cited by 85
Allelic exchange mutagenesis of nixA in Helicobacter pylori results in reduced nickel transport and urease activity
Bauerfeind, P., Garner, R. M., & Mobley, H. L. T. (1996) · Infection and Immunity · doi:10.1128/iai.64.7.2877-2880.1996 · Cited by 84
Functional Properties of the p33 and p55 Domains of the Helicobacter pylori Vacuolating Cytotoxin
Torres, V. J., Ivie, S. E., McClain, M. S., & Cover, T. L. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m501042200 · Cited by 84
The Mouse Colonizing Helicobacter pylori Strain SS1 May Lack a Functional cag Pathogenicity Island
Crabtree, J. E., Ferrero, R. L., & Kusters, J. G. (2002) · Helicobacter · doi:10.1046/j.1083-4389.2002.00071.x · Cited by 84
Self-citation
Detection of Helicobacter pylori DNA in Feces and Saliva by Polymerase Chain Reaction: a Review
Kabir, S. (2004) · Helicobacter · doi:10.1111/j.1083-4389.2004.00207.x · Cited by 84
Unique mechanism of for colonizing the gastric mucus
Yoshiyama, H., & Nakazawa, T. (2000) · Microbes and Infection · doi:10.1016/s1286-4579(00)00285-9 · Cited by 84
Cell Specificity of Helicobacter pylori Cytotoxin Is Determined by a Short Region in the Polymorphic Midregion
Ji, X., Fernandez, T., Burroni, D., et al. (2000) · Infection and Immunity · doi:10.1128/iai.68.6.3754-3757.2000 · Cited by 84
Coinfection Modulates Inflammatory Responses and Clinical Outcome of Helicobacter felis and Toxoplasma gondii Infections
Stoicov, C., Whary, M. T., Rogers, A. B., et al. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.5.3329 · Cited by 84
Distinct Variants of Helicobacter pylori cagA Are Associated with vacA Subtypes
van Doorn, L., Figueiredo, C., Sanna, R., Blaser, M. J., & Quint, W. G. V. (1999) · Journal of Clinical Microbiology · doi:10.1128/jcm.37.7.2306-2311.1999 · Cited by 84
Association between TNF- promoter polymorphism and Helicobacter pylori cagA subtype infection
Yea, S.-S., Yang, Y.-I., Jang, W. H., Lee, Y. J., Bae, H.-S., & Paik, K. (2001) · Journal of Clinical Pathology · doi:10.1136/jcp.54.9.703 · Cited by 84
Resistance to hydrogen peroxide in Helicobacter pylori: role of catalase (KatA) and Fur, and functional analysis of a novel gene product designated ‘KatA-associated protein’, KapA (HP0874)
Harris, A. G., Hinds, F. E., Beckhouse, A. G., Kolesnikow, T., & Hazell, S. L. (2002) · Microbiology · doi:10.1099/00221287-148-12-3813 · Cited by 84
The urea cycle of Helicobacter pylori
Mendz, G. L., & Hazell, S. L. (1996) · Microbiology · doi:10.1099/13500872-142-10-2959 · Cited by 83
Role of the AlpAB proteins and lipopolysaccharide in adhesion of Helicobacter pylori to human gastric tissue
Odenbreit, S., Faller, G., & Haas, R. (2002) · International Journal of Medical Microbiology · doi:10.1078/1438-4221-00204 · Cited by 83
Helicobacter pylori VacA cytotoxin associated with the bacteria increases epithelial permeability independently of its vacuolating activity
Pelicic, V., Reyrat, J., Sartori, L., et al. (1999) · Microbiology · doi:10.1099/13500872-145-8-2043 · Cited by 83
Vacuolating Toxin Production in Clinical Isolates of Helicobacter pylori with Different vacA Genotypes
Wang, H.-Y., Kuo, C.-H., Yeh, A. A. M., et al. (1998) · The Journal of Infectious Diseases · doi:10.1086/515600 · Cited by 82
The AmiE aliphatic amidase and AmiF formamidase of Helicobacter pylori: natural evolution of two enzyme paralogues
Skouloubris, S., Labigne-Roussel, A., & Reuse, H. D. (2001) · Molecular Microbiology · doi:10.1046/j.1365-2958.2001.02400.x · Cited by 82
Role of the Helicobacter pylori outer-membrane proteins AlpA and AlpB in colonization of the guinea pig stomach
de Jonge, R., Durrani, Z., Rijpkema, S. G. T., Kuipers, E. J., van Vliet, A. H. M., & Kusters, J. G. (2004) · Journal of Medical Microbiology · doi:10.1099/jmm.0.45551-0 · Cited by 82
Self-citation
Helicobacter pyloriReinfection Is Virtually Absent after Successful Eradication
van der Hulst, R. W. M., Rauws, E. A., Köycü, B., et al. (1997) · The Journal of Infectious Diseases · doi:10.1086/514023 · Cited by 82
Gastric colonization by Campylobacter pylori subsp. mustelae in ferrets
Fox, J. G., Cabot, E. B., Taylor, N. S., et al. (1988) · Infection and Immunity · doi:10.1128/iai.56.11.2994-2996.1988 · Cited by 81
Helicobacter pylori eradication: Novel therapy for immune thrombocytopenic purpura? A review of the literature
Jackson, S. C., Beck, P. L., Pineo, G. F., et al. (2005) · American Journal of Hematology · doi:10.1002/ajh.20250 · Cited by 81
Conserved Residues and Motifs in the NixA Protein ofHelicobacter pylori Are Critical for the High Affinity Transport of Nickel Ions
Fulkerson, J. F., Garner, R. M., & Mobley, H. L. T. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.1.235 · Cited by 81
Immunization against Natural Helicobacter pylori Infection in Nonhuman Primates
Dubois, A., Lee, C. K., Fiala, N., et al. (1998) · Infection and Immunity · doi:10.1128/iai.66.9.4340-4346.1998 · Cited by 81
Dependence of Helicobacter pylori Urease Activity on the Nickel-Sequestering Ability of the UreE Accessory Protein
Benoit, S. L., & Maier, R. J. (2003) · Journal of Bacteriology · doi:10.1128/jb.185.16.4787-4795.2003 · Cited by 81
Long‐term clinical outcome of Helicobacter pylori eradication for gastric mucosa‐associated lymphoid tissue lymphoma with a reference to second‐line treatment
Nakamura, S., Nakamura, S., Matsumoto, T., et al. (2005) · Cancer · doi:10.1002/cncr.21152 · Cited by 81
Acid-Responsive Gene Induction of Ammonia-Producing Enzymes in Helicobacter pylori Is Mediated via a Metal-Responsive Repressor Cascade
van Vliet, A. H. M., Kuipers, E. J., Stoof, J., Poppelaars, S. W., & Kusters, J. G. (2004) · Infection and Immunity · doi:10.1128/iai.72.2.766-773.2004 · Cited by 81
Self-citation
Production of a Cytotoxin by Helicobacter pylori
Leunk, R. D. (1991) · Clinical Infectious Diseases · doi:10.1093/clinids/13.supplement_8.s686 · Cited by 81
Gastric marginal zone lymphoma is associated with polymorphisms in genes involved in inflammatory response and antioxidative capacity
Rollinson, S. J., Levene, A., Mensah, F. K., Roddam, P. L., Allan, J. M., Diss, T. C., Roman, E., Jack, A., MacLennan, K., Dixon, M. F., et al. (2003) · Blood · doi:10.1182/blood-2002-12-3803 · Cited by 80
In Vivo Behavior of a Helicobacter pylori SS1 nixA Mutant with Reduced Urease Activity
Nolan, K. J., McGee, D. J., Mitchell, H. M., Kolesnikow, T., Harro, J. M., O'Rourke, J., Wilson, J. E., Danon, S. J., Moss, N. D., Mobley, H. L. T., et al. (2002) · Infection and Immunity · doi:10.1128/iai.70.2.685-691.2002 · Cited by 80
Antral Atrophy,Helicobacter pyloriColonization, and Gastric pH
Ruiz, B. A., Correa, P., Fontham, E. T. H., et al. (1996) · American Journal of Clinical Pathology · doi:10.1093/ajcp/105.1.96 · Cited by 79
Characterization of an Acidic-pH-Inducible Stress Protein (hsp70), a Putative Sulfatide Binding Adhesin, from Helicobacter pylori
Huesca, M., Goodwin, A., Bhagwansingh, A., Hoffman, P. S., & Lingwood, C. A. (1998) · Infection and Immunity · doi:10.1128/iai.66.9.4061-4067.1998 · Cited by 79
Association of Helicobacter pylori Antioxidant Activities with Host Colonization Proficiency
Olczak, A. A., Seyler, R. W., Olson, J. W., & Maier, R. J. (2002) · Infection and Immunity · doi:10.1128/iai.71.1.580-583.2003 · Cited by 79
Helicobacter pylori Induces AGS Cell Motility and Elongation via Independent Signaling Pathways
Moese, S., Selbach, M., Kwok, T., Brinkmann, V., König, W., Meyer, T. F., & Backert, S. (2004) · Infection and Immunity · doi:10.1128/iai.72.6.3646-3649.2004 · Cited by 79
Basis for the Management of Drug-Resistant Helicobacter pylori Infection
graud, F. M. (2004) · Drugs · doi:10.2165/00003495-200464170-00003 · Cited by 78
The i genome sequence: G genome sequence: Genetic factors for long life in the gastric mucosa
Berg, D. E., Hoffman, P. S., Appelmelk, B. J., & Kusters, J. G. (1997) · Trends in Microbiology · doi:10.1016/s0966-842x(97)01164-5 · Cited by 78
Self-citation
Nutritional requirements for growth of Helicobacter pylori
Nedenskov, P. (1994) · Applied and Environmental Microbiology · doi:10.1128/aem.60.9.3450-3453.1994 · Cited by 77
The Story So Far:Helicobacter Pyloriand Gastric Autoimmunity
Bergman, M. P., Vandenbroucke‐Grauls, C. M. J. E., Appelmelk, B. J., D’Elios, M. M., Amedei, A., Azzurri, A., Benagiano, M., & Prete, G. D. (2005) · International Reviews of Immunology · doi:10.1080/08830180590884648 · Cited by 77
Sites of pH regulation of the urea channel of Helicobacter pylori
Weeks, D. L., & Sachs, G. M. (2001) · Molecular Microbiology · doi:10.1046/j.1365-2958.2001.02466.x · Cited by 77
Presence of Active Aliphatic Amidases in Helicobacter Species Able To Colonize the Stomach
Bury‐Moné, S., Skouloubris, S., Dauga, C., Thiberge, J.-M., Dailidiene, D., Berg, D. E., Labigne-Roussel, A., & Reuse, H. D. (2003) · Infection and Immunity · doi:10.1128/iai.71.10.5613-5622.2003 · Cited by 77
IL1B and IL1RN polymorphic genes and Helicobacter pylori cagA strains decrease the risk of reflux esophagitis
Queiroz, D. M. M., Guerra, J. B., Rocha, G. A., et al. (2004) · Gastroenterology · doi:10.1053/j.gastro.2004.03.069 · Cited by 76
Response of Campylobacter pyloridis to antibiotics, bismuth and an acid-reducing agent in vitro--an ultrastructural study
Armstrong, J. A., Wee, S. H., Goodwin, C. S., et al. (1987) · Journal of Medical Microbiology · doi:10.1099/00222615-24-4-343 · Cited by 76
Structural, functional and mutational analysis of the pfr gene encoding a ferritin from Helicobacter pylori
Bereswill, S., Waidner, U., Odenbreit, S., Lichte, F., Fassbinder, F., Bode, G., & Kist, M. (1998) · Microbiology · doi:10.1099/00221287-144-9-2505 · Cited by 76
VIRULENCE GENES AND HOST AND β GENES INTERPLAY IN FAVOURING THE DEVELOPMENT OF PEPTIC ULCER AND INTESTINAL METAPLASIA
Zambon, C., Basso, D., Navaglia, F., Germanò, G., Gallo, N., Milazzo, M., Greco, E., Fogar, P., Mazza, S., Mario, F. D., et al. (2002) · Cytokine · doi:10.1006/cyto.2002.0891 · Cited by 76
Receptor affinity purification of a lipid-binding adhesin from Helicobacter pylori
Lingwood, C. A., Wasfy, G., Han, H., & Huesca, M. (1993) · Infection and Immunity · doi:10.1128/iai.61.6.2474-2478.1993 · Cited by 75
CD14 C(-260)→T polymorphism, plasma levels of the soluble endotoxin receptor CD14, their association with chronic infections and risk of stable coronary artery disease
Köenig, W., Khuseyinova, N., Hoffmann, M. M., März, W., Fröhlich, M., Hoffmeister, A., Brenner, H., & Rothenbacher, D. (2002) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(02)01937-x · Cited by 75
Reduced colonization of gastric mucosa by Helicobacter pylori in mice deficient in interleukin‐101
Chen, W., Shu, D., & CHADWICK, V. S. (2001) · Journal of Gastroenterology and Hepatology · doi:10.1046/j.1440-1746.2001.02459.x · Cited by 75
Systematic review and meta‐analysis: is 1‐week proton pump inhibitor‐based triple therapy sufficient to heal peptic ulcer?
Gisbert, J. P., & Pajares, J. M. (2005) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2005.02418.x · Cited by 73
Low‐dose furazolidone in triple and quadruple regimens for Helicobacter pylori eradication
Fakheri, H. T., Merat, S., Hosseini, V., et al. (2003) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2003.01822.x · Cited by 73
Expression of mRNA for Interferon-Gamma, Interleukin-10, and Interleukin-12 (p40) in Normal Gastric Mucosa and in Mucosa Infected withHelicobacter pylori
Karttunen, R. A., Karttunen, T. J., Yousfi, M. M., et al. (1997) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365529709025058 · Cited by 72
Gastric Ulcer, Atrophic Gastritis, and Intestinal Metaplasia Caused byHelicobacter pyloriInfection in Mongolian Gerbils
Honda, S. (1998) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365529850171990 · Cited by 72
Campylobacter mustelae, a New Species Resulting from the Elevation of Campylobacter pylori subsp. mustelae to Species Status
Fox, J. G., CHILVERS, T., Goodwin, C. S., Taylor, N. S., Edmonds, P., Sly, L. I., & Brenner, D. J. (1989) · International Journal of Systematic Bacteriology · doi:10.1099/00207713-39-3-301 · Cited by 72
Influence of medium composition on the growth and antigen expression of Helicobacter pylori
Walsh, E. J., & Moran, A. P. (1997) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.1997.00164.x · Cited by 71
Comparison of different routes of vaccination for eliciting antibody responses in the human stomach
Johansson, E.-L., Bergquist, C., Edebo, A., et al. (2003) · Vaccine · doi:10.1016/j.vaccine.2003.09.002 · Cited by 71
Genetic organization and heterogeneity of the iceA locus of Helicobacter pylori
Figueiredo, C., Quint, W. G. V., Sanna, R., Sablon, E., Donahue, J. P., Xu, Q. S., Miller, G. G., Peek, R. M., Blaser, M. J., & van Doorn, L. (2000) · Gene · doi:10.1016/s0378-1119(00)00054-8 · Cited by 71
Clarithromycin for the Eradication of Helicobacter Pylori
Graham, D. Y., Opekun, A. R., & Klein, P. (1993) · Journal of Clinical Gastroenterology · doi:10.1097/00004836-199306000-00004 · Cited by 71
Helicobacter pylori toxin VacA is transferred to host cells via a novel contact-dependent mechanism
Ilver, D., Barone, S., Mercati, D., Lupetti, P., & Telford, J. L. (2004) · Cellular Microbiology · doi:10.1046/j.1462-5822.2003.00349.x · Cited by 71
Safety of oral immunisation with recombinant urease in patients with Helicobacter pylori infection
Kreiss, C. M., Buclin, T., Cosma, M., et al. (1996) · The Lancet · doi:10.1016/s0140-6736(96)91119-8 · Cited by 71
Association of Helicobacter pylori genotype with gastroesophageal reflux disease and other upper gastrointestinal diseases
Fallone, C. A., Barkun, A. N., Göttke, M. U., et al. (2000) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2000.01970.x · Cited by 71
Genetic evidence for histidine kinase HP165 being an acid sensor of Helicobacter pylori
Pflock, M., Dietz, P., SchÃ¤r, J., & Beier, D. (2004) · FEMS Microbiology Letters · doi:10.1016/j.femsle.2004.03.023 · Cited by 70
The effect of environmental cues on the differentiation of myofibroblasts in peritoneal granulation tissue
(2000) · doi:10.1002/1096-9896(2000)9999:9999 · Cited by 70
Rapid Loss of Motility of Helicobacter pylori in the Gastric Lumen In Vivo
Schreiber, S., Bücker, R., Groll, C., et al. (2005) · Infection and Immunity · doi:10.1128/iai.73.3.1584-1589.2005 · Cited by 70
The Physiology and Metabolism of the Human Gastric Pathogen Helicobacter pylori
Kelly, D. J. (1998) · Advances in microbial physiology/Advances in Microbial Physiology · doi:10.1016/s0065-2911(08)60131-9 · Cited by 69
Roles of conserved nucleotide-binding domains in accessory proteins, HypB and UreG, in the maturation of nickel-enzymes required for efficient Helicobacter pylori colonization
Mehta, N. S., Benoit, S. L., & Maier, R. J. (2003) · Microbial Pathogenesis · doi:10.1016/s0882-4010(03)00151-7 · Cited by 69
The Impact of Helicobacter pylori Eradication on Peptic Ulcer Healing
Treiber, G., & Lambert, J. R. (1998) · The American Journal of Gastroenterology · doi:10.1016/s0002-9270(98)00214-7 · Cited by 69
Helicobacter pylori Adhesins: Review and Perspectives
Evans, D. J., & Evans, D. G. (2000) · Helicobacter · doi:10.1046/j.1523-5378.2000.00029.x · Cited by 68
Helicobacter pyloriinduces apoptosis of rat gastric parietal cells
Neu, B., Randlkofer, P., Neuhofer, M., et al. (2002) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00546.2001 · Cited by 68
An ultrastructural study of Helicobacter mustelae and evidence of a specific association with gastric mucosa
O’Rourke, J., Lee, A., & Fox, J. G. (1992) · Journal of Medical Microbiology · doi:10.1099/00222615-36-6-420 · Cited by 68
Helicobacter pylori Resists Phagocytosis by Macrophages: Quantitative Assessment by Confocal Microscopy and Fluorescence-Activated Cell Sorting
Ramarao, N., & Meyer, T. F. (2001) · Infection and Immunity · doi:10.1128/iai.69.4.2604-2611.2001 · Cited by 68
The significance of cagA and vacA subtypes of Helicobacter pylori in the pathogenesis of inflammation and peptic ulceration.
Gunn, M., Stephens, J. C., Stewart, J. A., et al. (1998) · Journal of Clinical Pathology · doi:10.1136/jcp.51.10.761 · Cited by 67
New Pathogenicity Marker Found in the Plasticity Region of theHelicobacter pyloriGenome
Santos, A., Queiroz, D. M. M., Ménard, A., Marais, A., Rocha, G. A., de Oliveira, C. A., Nogueira, A. M. M. F., de Uzeda, M., & Mégraud, F. (2003) · Journal of Clinical Microbiology · doi:10.1128/jcm.41.4.1651-1655.2003 · Cited by 67
Helicobacter pylori ABC transporter: effect of allelic exchange mutagenesis on urease activity
Hendricks, J. K., & Mobley, H. L. T. (1997) · Journal of Bacteriology · doi:10.1128/jb.179.18.5892-5902.1997 · Cited by 66
Occurrence of gastric ulcers in gnotobiotic piglets colonized by Helicobacter pylori
Krakowka, S. G., Eaton, K. A., & Rings, D. M. (1995) · Infection and Immunity · doi:10.1128/iai.63.6.2352-2355.1995 · Cited by 66
Potential Role of CagA in the Inhibition of T Cell Reactivity in Helicobacter pylori Infections
Paziak-Domańska, B., Chmiela, M., Jarosińska, A., et al. (2000) · Cellular Immunology · doi:10.1006/cimm.2000.1654 · Cited by 66
Colonization of Helicobacter pylori in the Gastric Mucosa of Mongolian Gerbils
Yokota, K., Kurebayashi, Y., Takayama, Y., et al. (1991) · Microbiology and Immunology · doi:10.1111/j.1348-0421.1991.tb01577.x · Cited by 65
The role of epithelial Toll-like receptor expression in host defense and microbial tolerance
Hornef, M. W., & Bogdan, C. (2005) · Journal of Endotoxin Research · doi:10.1177/09680519050110020901 · Cited by 65
Colony Variation of Helicobacter pylori: Pathogenic Potential Is Correlated to Cell Wall Lipid Composition
Bukholm, G., Tannæs, T. M., Nedenskov, P., et al. (1997) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365529709025079 · Cited by 65
The Functional Status of the Helicobacter pylori sabB Adhesin Gene as a Putative Marker for Disease Outcome
de Jonge, R., Pot, R. G. J., Loffeld, R. J. L. F., van Vliet, A. H. M., Kuipers, E. J., & Kusters, J. G. (2004) · Helicobacter · doi:10.1111/j.1083-4389.2004.00213.x · Cited by 65
Self-citation
Evaluation of two monkey species (Macaca mulatta and Macaca fascicularis) as possible models for human Helicobacter pylori disease
Euler, A. R., Zurenko, G. E., Moe, J. B., et al. (1990) · Journal of Clinical Microbiology · doi:10.1128/jcm.28.10.2285-2290.1990 · Cited by 64
Bactericidal effect of bovine normal and immune serum, colostrum and milk against Helicobacter pylori
Korhonen, H. J. T., Syväoja, E., Ahola‐Luttila, H., et al. (1995) · Journal of Applied Bacteriology · doi:10.1111/j.1365-2672.1995.tb03112.x · Cited by 64
Transport and storage ofHelicobacter pylori from gastric mucosal biopsies and clinical isolates
Han, S. W., Flamm, R. K., Hachem, C., et al. (1995) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/bf02116531 · Cited by 63
Association study of a functional Toll-like receptor 4 polymorphism with susceptibility to gastric mucosa-associated lymphoid tissue lymphoma
Hellmig, S., Fischbach, W., Goebeler-Kolve, M.-E., et al. (2005) · Leukemia & lymphoma/Leukemia and lymphoma · doi:10.1080/1042819050086451 · Cited by 63
Isolation and characterization of a conserved porin protein from Helicobacter pylori
Doig, P. C., Exner, M. M., Hancock, R. E. W., & Trevor J. TRUST (1995) · Journal of Bacteriology · doi:10.1128/jb.177.19.5447-5452.1995 · Cited by 63
Evolution of Helicobacter pylori: the role of recombination
Suerbaum, S., & Achtman, M. (1999) · Trends in Microbiology · doi:10.1016/s0966-842x(99)01505-x · Cited by 63
Clinical Significance ofHelicobacterSpecies Other thanHelicobacter pylori
Solnick, J. V. (2003) · Clinical Infectious Diseases · doi:10.1086/346038 · Cited by 63
Helicobacter pylori modulation of gastric acid.
Calam, J. (2000) · PubMed · Cited by 62
Cell Lysis is Responsible for the Appearance of Extracellular Urease in Helicobacter pylori
Marcus, E. A., & Scott, D. R. (2001) · Helicobacter · doi:10.1046/j.1523-5378.2001.00014.x · Cited by 62
Role of a Bacterial Organic Hydroperoxide Detoxification System in Preventing Catalase Inactivation
Wang, G., Conover, R. C., Benoit, S. L., Olczak, A. A., Olson, J. W., Johnson, M. K., & Maier, R. J. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m408450200 · Cited by 62
Helicobacter felis Infection in Dogs: Effect on Gastric Structure and Function
Simpson, K. W., McDonough, P. L., Strauss‐Ayali, D., et al. (1999) · Veterinary Pathology · doi:10.1354/vp.36-3-237 · Cited by 62
Helicobacter pylori Neutrophil‐Activating Protein Stimulates Tissue Factor and Plasminogen Activator Inhibitor–2 Production by Human Blood Mononuclear Cells
Montemurro, P., Barbuti, G., Dundon, W. G., et al. (2001) · The Journal of Infectious Diseases · doi:10.1086/319280 · Cited by 62
Helicobacter pyloriand cholesterol gallstone formation in C57L/J mice: a prospective study
Maurer, K. J., Rogers, A. B., Ge, Z., Wiese, A. J., Carey, M. C., & Fox, J. G. (2005) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00272.2005 · Cited by 61
Phase Variation in the Helicobacter pylori Phospholipase A Gene and Its Role in Acid Adaptation
Tannæs, T. M., Dekker, N., Bukholm, G., Bijlsma, J. J. E., & Appelmelk, B. J. (2001) · Infection and Immunity · doi:10.1128/iai.69.12.7334-7340.2001 · Cited by 61
Cloning, expression and sequencing of Helicobacter felis urease genes
Ferrero, R. L., & Labigne, A. (1993) · Molecular Microbiology · doi:10.1111/j.1365-2958.1993.tb01693.x · Cited by 61
Production of IL-1 receptor antagonist by hepatocytes is regulated as an acute-phase proteinin vivo
Gabay, C., Gigley, J. P., Sipe, J. D., Arend, W. P., & Fantuzzi, G. (2001) · European Journal of Immunology · doi:10.1002/1521-4141(200102)31:2 · Cited by 61
Polymorphism of interleukin-1β affects the eradication rates of Helicobacter pylori by triple therapy
Furuta, T., Shirai, N., Fang, X., et al. (2004) · Clinical Gastroenterology and Hepatology · doi:10.1016/s1542-3565(03)00288-x · Cited by 61
Decreasing prevalence of helicobacter antibodies in Finland, with reference to the decreasing incidence of gastric cancer
Rehnberg-Laiho, L., Rautelin, H. I., Koskela, P. U., et al. (2001) · Epidemiology and Infection · doi:10.1017/s0950268801005027 · Cited by 61
Survival of Helicobacter pylori in ready-to-eat foods at 4°C
Poms, R. E., & Tatini, S. R. (2001) · International Journal of Food Microbiology · doi:10.1016/s0168-1605(00)00441-4 · Cited by 60
Treatment of Antibiotic-ResistantHelicobacter pyloriInfection
Perri, F., Festa, V., & Andriulli, A. (1998) · New England Journal of Medicine · doi:10.1056/nejm199807023390116 · Cited by 60
CagAand the Outcome ofHelicobacter pyloriInfection
Blaser, M. J., & Crabtree, J. E. (1996) · American Journal of Clinical Pathology · doi:10.1093/ajcp/106.5.565 · Cited by 60
GSTT1 and GSTM1 gene polymorphisms and gastric cancer in a high‐risk italian population
Palli, D., Saieva, C., Gemma, S., et al. (2005) · International Journal of Cancer · doi:10.1002/ijc.20864 · Cited by 59
Helicobacter pylori prevalences and risk factors among school beginners in a German urban center and its rural county.
Herbarth, O., Krumbiegel, P., Fritz, G. J., et al. (2001) · Environmental Health Perspectives · doi:10.1289/ehp.01109573 · Cited by 59
Role of Hpn and NixA of Helicobacter pylori in Susceptibility and Resistance to Bismuth and Other Metal Ions
Mobley, H. L. T., Garner, R. M., Chippendale, G. R., et al. (1999) · Helicobacter · doi:10.1046/j.1523-5378.1999.99286.x · Cited by 59
Helicobacter pylori Infection in Different Generations of Hispanics in the San Francisco Bay Area
Tsai, C. J., Perry, S., Sanchez, L. H. G., et al. (2005) · American Journal of Epidemiology · doi:10.1093/aje/kwi207 · Cited by 59
Helicobacter pylori and Complex Gangliosides
Roche, N., Ångström, J., Hurtig, M., et al. (2004) · Infection and Immunity · doi:10.1128/iai.72.3.1519-1529.2004 · Cited by 59
Inflammatory Cytokine mRNA Expression during Early and PersistentHelicobacter pyloriInfection in Nonhuman Primates
Harris, P. R., Smythies, L. E., Smith, P. D., et al. (2000) · The Journal of Infectious Diseases · doi:10.1086/315257 · Cited by 59
Adhesion of Helicobacter pylori to polarized T84 human intestinal cell monolayers is pH dependent
Corthésy-Theulaz, I. E., Porta, N., Pringault, E., Racine, L., Bogdanova, A. A., Kraehenbühl, J. P., Blum, A. L., & Michetti, P. (1996) · Infection and Immunity · doi:10.1128/iai.64.9.3827-3832.1996 · Cited by 59
Propeptide of type I procollagen is predictive of posttreatment bone mass gain in adult celiac disease
Corazza, G. R., Stefano, M. D., Jorizzo, R. A., Cecchetti, L., Minguzzi, L., & Gasbarrini, A. (1997) · Gastroenterology · doi:10.1016/s0016-5085(97)70081-7 · Cited by 58
Role of vacuolating cytotoxin in gastritis due to Helicobacter pylori in gnotobiotic piglets
Eaton, K. A., Cover, T. L., Tummuru, M. K. R., Blaser, M. J., & Krakowka, S. G. (1997) · Infection and Immunity · doi:10.1128/iai.65.8.3462-3464.1997 · Cited by 58
High intake of selenium, beta-carotene, and vitamins A, C, and E reduces growth of Helicobacter pylori in the guinea pig.
Sjunnesson, H., Sturegård, E., Wïllén, R., et al. (2001) · PubMed · Cited by 57
The Incidence of Helicobacter pylori Acquisition in Children of a Canadian First Nations Community and the Potential for Parent‐to‐Child Transmission
Sinha, S. K., Martin, B. D., Gold, B. D., et al. (2004) · Helicobacter · doi:10.1111/j.1083-4389.2004.00199.x · Cited by 57
Cloning and allelic exchange mutagenesis of two flagellin genes of Helicobacter felis
Josenhans, C., Ferrero, R. L., Labigne, A., et al. (1999) · Molecular Microbiology · doi:10.1046/j.1365-2958.1999.01478.x · Cited by 57
Genetic evidence for histidine kinase HP165 being an acid sensor ofHelicobacter pylori
Pflock, M., Dietz, P., Schär, J., & Beier, D. (2004) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2004.tb09512.x · Cited by 57
The Impact of Helicobacter pylori Eradication on Peptic Ulcer Healing
Treiber, G. G., & Lambert, J. (1998) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.1998.00333.x · Cited by 57
Egg yolk emulsion agar, a new medium for the cultivation of Helicobacter pylori
Westblom, T. U., Madan, E., & Midkiff, B. R. (1991) · Journal of Clinical Microbiology · doi:10.1128/jcm.29.4.819-821.1991 · Cited by 56
TheHelicobacter pyloriplasticity region locusjhp0947–jhp0949is associated with duodenal ulcer disease and interleukin-12 production in monocyte cells
de Jonge, R., Kuipers, E. J., Langeveld, S. C. L., Loffeld, R. J. L. F., Stoof, J., van Vliet, A. H. M., & Kusters, J. G. (2004) · FEMS Immunology & Medical Microbiology · doi:10.1016/j.femsim.2004.03.003 · Cited by 56
Self-citation
Composition and Gene Expression of the cag Pathogenicity Island in Helicobacter pylori Strains Isolated from Gastric Carcinoma and Gastritis Patients in Costa Rica
Occhialini, A., Marais, A., Urdaci, M. C., Sierra, R., Muñóz, N., Covacci, A., & Mégraud, F. (2001) · Infection and Immunity · doi:10.1128/iai.69.3.1902-1908.2001 · Cited by 55
Correlation betweenHelicobacter pyloriOipA Protein Expression andoipAGene Switch Status
Kudo, T., Nurgalieva, Z. Z., Conner, M. E., et al. (2004) · Journal of Clinical Microbiology · doi:10.1128/jcm.42.5.2279-2281.2004 · Cited by 55
Treatment of Helicobacter pylori
Bytzer, P. M., & O'Morain, C. A. (2005) · Helicobacter · doi:10.1111/j.1523-5378.2005.00333.x · Cited by 55
Promoter polymorphisms of tumor necrosis factor‐α are associated with risk of gastric mucosa–associated lymphoid tissue lymphoma
Wu, M., Chen, L., Shun, C., et al. (2004) · International Journal of Cancer · doi:10.1002/ijc.20199 · Cited by 54
The Helicobacter pylori vacuoloating cytotoxin: from cellular vacuolation to immunosuppressive activities
Gebert, B., Fisher, W. E., & Haas, R. (2004) · Springer eBooks · doi:10.1007/s10254-004-0027-3 · Cited by 54
Toll‐like Receptor 2‐Mediated Gene Expression in Epithelial Cells During Helicobacter pylori Infection
Ding, S., Torok, A. M., Smith, M. F., & Goldberg, J. B. (2005) · Helicobacter · doi:10.1111/j.1523-5378.2005.00311.x · Cited by 54
Nickel concentrations in serum and urine of patients with nickel eczema
Christensen, J. (1999) · Toxicology Letters · doi:10.1016/s0378-4274(99)00088-0 · Cited by 54
Rhesus monkey (Macaca mulatta) model of Helicobacter pylori: noninvasive detection and derivation of specific-pathogen-free monkeys.
Solnick, J. V., Canfield, D. R., Yang, S., et al. (1999) · PubMed · Cited by 54
Helicobacter pylori eradication is superior to ulcer healing with or without maintenance therapy to prevent further ulcer haemorrhage
Sharma, V. K., Sahai, A. V., Corder, F. A., & Howden, C. W. (2001) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2001.01134.x · Cited by 53
Rhesus monkey gastric mucins: oligomeric structure, glycoforms and Helicobacter pylori binding
Lindén, S. K., Borén, T., Dubois, A., et al. (2004) · Biochemical Journal · doi:10.1042/bj20031557 · Cited by 53
Effect of Dietary Anti‐Urease Immunoglobulin Y onHelicobacter pyloriInfection in Mongolian Gerbils
Nomura, S., Suzuki, H., Masaoka, T., et al. (2005) · Helicobacter · doi:10.1111/j.1523-5378.2005.00290.x · Cited by 53
Helicobacter pylori: recombination, population structure and human migrations
Suerbaum, S., & Achtman, M. (2004) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2004.06.014 · Cited by 53
Experimental Helicobacter pylori Infection Induces Antral Gastritis and Gastric Mucosa-Associated Lymphoid Tissue in Guinea Pigs
Shomer, N. H., Dangler, C. A., Whary, M. T., & Fox, J. G. (1998) · Infection and Immunity · doi:10.1128/iai.66.6.2614-2618.1998 · Cited by 53
Bacteriophages in Helicobacter (Campylobacter) pylori
Schmid, E. N., Recklinghausen, G. V., & Ansorg, R. (1990) · Journal of Medical Microbiology · doi:10.1099/00222615-32-2-101 · Cited by 53
The efficacy of furazolidone-based quadruple therapy for eradication of Helicobacter pylori infection in Iranian patients resistant to metronidazole-based quadruple therapy.
Ebrahimi-Daryani, N., Mirmomen, S., Mansour‐Ghanaei, F., Noormohammadpoor, P., Sotodehmanesh, R., Haghpanah, B., & Bahrami, H. (2003) · PubMed · Cited by 52
Helicobacter pylori and Schistosoma japonicum co-infection in a Chinese population: helminth infection alters humoral responses to H. pylori and serum pepsinogen I/II ratio
Du, Y., AGNEW, A. M., Ye, X.-P., et al. (2005) · Microbes and Infection · doi:10.1016/j.micinf.2005.05.017 · Cited by 52
Increased frequency of activated T-cells in theHelicobacter pylori-infected antrum and duodenum
StrÃ¶mberg, E., Lundgren, A., Edebo, A., et al. (2003) · FEMS Immunology & Medical Microbiology · doi:10.1016/s0928-8244(03)00026-9 · Cited by 52
GastricHelicobacterSpecies Infection in Murine and Gerbil Models: Comparative Analysis of Effects ofH. pyloriandH. felison Gastric Epithelial Cell Proliferation
Court, M., Robinson, P. A., Dixon, M. F., et al. (2002) · The Journal of Infectious Diseases · doi:10.1086/344321 · Cited by 52
Properties of the P-Type ATPases Encoded by the copAP Operons of Helicobacter pylori and Helicobacter felis
Bayle, D., Wängler, S., Weitzenegger, T., Steinhilber, W., Volz, J., Przybylski, M., Schäfer, K. P., Sachs, G. M., & Melchers, K. (1998) · Journal of Bacteriology · doi:10.1128/jb.180.2.317-329.1998 · Cited by 52
Detection of identical Helicobacter DNA in the stomach and in the non-cirrhotic liver of patients with hepatocellular carcinoma
Verhoef, C. J., Pot, R. G. J., de Man, R. A., et al. (2003) · European Journal of Gastroenterology & Hepatology · doi:10.1097/00042737-200311000-00004 · Cited by 50
Involvement of Myeloid Dendritic Cells in the Development of Gastric Secondary Lymphoid Follicles inHelicobacter pylori-Infected Neonatally Thymectomized BALB/c Mice
Nishi, T., Okazaki, K., Kawasaki, K., Fukui, T., Tamaki, H., Matsuura, M., Asada, M., Watanabe, T., Uchida, K., Watanabe, N., et al. (2003) · Infection and Immunity · doi:10.1128/iai.71.4.2153-2162.2003 · Cited by 50
Cloning, Expression, and Catalytic Activity of Helicobacter hepaticus Urease
Beckwith, C. S., McGee, D. J., Mobley, H. L. T., & Riley, L. K. (2001) · Infection and Immunity · doi:10.1128/iai.69.9.5914-5920.2001 · Cited by 49
Cure ofHelicobacter pyloriInfection and Resolution of Gastritis by Adoptive Transfer of Splenocytes in Mice
Eaton, K. A., & Mefford, M. (2001) · Infection and Immunity · doi:10.1128/iai.69.2.1025-1031.2001 · Cited by 49
GSTP1 polymorphisms and gastric cancer in a high-risk Chinese population
Setiawan, V. W., Zhang, Z., Yu, G., et al. (2001) · Cancer Causes & Control · doi:10.1023/a:1011261602940 · Cited by 48
In Vitro Aging of Helicobacter pylori: Changes in Morphology, Intracellular Composition and Surface Properties
Enroth, H., Wreiber, K., Rigo, R., et al. (1999) · Helicobacter · doi:10.1046/j.1523-5378.1999.09034.x · Cited by 48
The role of the neutrophil and phagocytosis in infection caused by Helicobacter pylori
Allen, L. H. (2001) · Current Opinion in Infectious Diseases · doi:10.1097/00001432-200106000-00005 · Cited by 48
Analysis of iceA genotypes in South African Helicobacter pylori strains and relationship to clinically significant disease
Kidd, M. S., Peek, R. M., Lastovica, A. J., Israel, D. A., Kummer, A. F., & Louw, J. A. (2001) · Gut · doi:10.1136/gut.49.5.629 · Cited by 47
Gastric Function in Dogs with Naturally Acquired Gastric Helicobacter spp. Infection
Simpson, K. W., Strauss‐Ayali, D., McDonough, P. L., et al. (1999) · Journal of Veterinary Internal Medicine · doi:10.1111/j.1939-1676.1999.tb02203.x · Cited by 46
TNF-α and interleukin 1 activate gastrin gene expression via MAPK- and PKC-dependent mechanisms
Suzuki, T., Grand, E., Bowman, C., et al. (2001) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.2001.281.6.g1405 · Cited by 46
Use of antibiotics to prevent hepatitis and typhlitis in male scid mice spontaneously infected with Helicobacter hepaticus.
Russell, R. J., Haines, D. C., Anver, M. R., et al. (1995) · PubMed · Cited by 45
Regulation of transcription in Helicobacter pylori: simple systems or complex circuits?
Scarlato, V., Delany, I., Spohn, G., & Beier, D. (2001) · International Journal of Medical Microbiology · doi:10.1078/1438-4221-00107 · Cited by 45
TNF Gene Polymorphisms and Helicobacter Pylori Infection in Gastric Carcinogenesis in Chinese Population
Li, C., Xia, B., Yang, Y., et al. (2005) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2005.40806.x · Cited by 45
Heterogeneity of Helicobacter pylori cag genotypes in experimentally infected mice
Sozzi, M., Crosatti, M., Kim, S.-K., Romero, J., & Blaser, M. J. (2001) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2001.tb10828.x · Cited by 45

Flagged first, then by citations

Research works printed but not linked: 8

10.1016/S0002-9270(01)02335-8 · DOI
Fox, J. G. 1998. Anatomy of the ferret, p. 19-69. In J. G. Fox (ed.), Biology and diseases of the ferret. The Williams & Wilkins Co., Baltimore, Md.
Fox, J. G. 1995. Nonhuman reservoirs of Helicobacter pylori. Aliment. Pharmacol. Ther.9(Suppl. 2):93-103.
Krienitz, W. 1906. Ueber das auftreten von mageninhalt bei carcinoma ventriculi. Dtsch. Med. Wochenschr.22:872.
Luger, A. 1917. Ueber spirochaeten und fusiforme bazillen im darm, mit einer beitrag zur frage der lamblien-enteritis. Wiein. Klin. Wochenschr.52:1643-1647.
Mellgard, B., S. Arvidsson, A. Lee, G. Sundell, and H. Larsson. 1994. Helicobacter felis infected rat as a model for Helicobacter pylori infection, colonisation pattern and inflammatory response. Am. J. Gastroenterol.89:1320.
Sakamoto, S., T. Watanabe, T. Tokumaru, H. Takagi, H. Nakazato, and K. O. Lloyd. 1989. Expression of Lewis a, Lewis b, Lewis x, Lewis y, sialyl-Lewis a, and sialyl-Lewis x blood group antigens in human gastric carcinoma and in normal gastric tissue. Cancer Res.49:745-752.
Stolte, M., G. Kroher, A. Meining, A. Morgner, E. Bayerdörffer, and B. Bethke. 1997. A comparison of Helicobacter pylori and H. heilmannii gastritis. A matched control study involving 404 patients. Scand. J. Gastroenterol.32:28-33.

Sorted by citations

Nanomaterials and nanoparticles: Sources and toxicity
Buzea, C., Pacheco, I. I., & Robbie, K. (2007) · Biointerphases · doi:10.1116/1.2815690 · Cited by 3,789
Influence of diet on the gut microbiome and implications for human health
Singh, R. K., Chang, H.-W., Yan, D., Lee, K. M., Ucmak, D., Wong, K., Abrouk, M., Farahnik, B., Nakamura, M., Zhu, T. H., et al. (2017) · Journal of Translational Medicine · doi:10.1186/s12967-017-1175-y · Cited by 2,599
Organoids as an in vitro model of human development and disease
Fatehullah, A., Tan, S. H., & Barker, N. (2016) · Nature Cell Biology · doi:10.1038/ncb3312 · Cited by 1,508
Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis -induced colon tumorigenesis
Goodwin, A. C., Shields, C. E. D., Wu, S., Huso, D. L., Wu, X., Murray-Stewart, T. R., Hacker-Prietz, A., Rabizadeh, S., Woster, P. M., Sears, C. L., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1010203108 · Cited by 612
Tissue–electronics interfaces: from implantable devices to engineered tissues
Feiner, R., & Dvir, T. (2017) · Nature Reviews Materials · doi:10.1038/natrevmats.2017.76 · Cited by 595

See all 2,526

Authors: Kusters, J. G., van Vliet, A. H. M., & Kuipers, E. J.
Affiliations: Erasmus MC (NL)
Department of Gastroenterology and Hepatology, Erasmus MC—University Medical Center, Rotterdam, The Netherlands
ORCID: Kusters, Johannes G.
Kuipers, Ernst J.
Venue: Clinical Microbiology Reviews
Publisher: American Society for Microbiology
Published: 2006-07
Volume: 19
Issue: 3
Pages: 449-490
ISSN: 0893-8512 (ISSN-L)
1098-6618
DOI: 10.1128/cmr.00054-05
PMC: PMC1539101
OpenAlex: W2153354382
Cited by: 2,526
References: 732
Citations by year: 2026: 93 · 2025: 127 · 2024: 117 · 2023: 119 · 2022: 133 · 2021: 180 · 2020: 174 · 2019: 153 · 2018: 129 · 2017: 144 · 2016: 137 · 2015: 140 · 2014: 172 · 2013: 140 · 2012: 97
FWCI: 15.43
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: journals.asm.org/non-commercial-tdm-license (tdm)
Locations: Clinical Microbiology Reviews (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
EUR Research Repository (Erasmus University Rotterdam) (publishedVersion)
EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
RePub (Erasmus University Rotterdam) (submittedVersion, other-oa)
Surrey Research Insight Open Access (The University of Surrey) (submittedVersion)
Topics: Health Sciences › Medicine › Gastroenterology › Helicobacter pylori-related gastroenterology studies
Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
Life Sciences › Agricultural and Biological Sciences › Food Science › Salmonella and Campylobacter epidemiology
Keywords: Helicobacter pylori, pathogenesis, bacterial colonization, chronic active gastritis, peptic ulcer, gastric adenocarcinoma, gastric MALT lymphoma, host-pathogen interaction, gastric acid secretion, CagA, VacA, virulence factors
MeSH terms: Animals, Gastritis, Guinea Pigs, Humans, Peptic Ulcer, Stomach Neoplasms, Helicobacter pylori, Helicobacter Infections, Virulence Factors, Mice

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