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Cited by 632

The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.

Blood Groups in Infection and Host Susceptibility

Open access
Cooling, Laura·2015·Clinical Microbiology Reviews

Abstract

SUMMARY: Blood group antigens represent polymorphic traits inherited among individuals and populations. At present, there are 34 recognized human blood groups and hundreds of individual blood group antigens and alleles. Differences in blood group antigen expression can increase or decrease host susceptibility to many infections. Blood groups can play a direct role in infection by serving as receptors and/or coreceptors for microorganisms, parasites, and viruses. In addition, many blood group antigens facilitate intracellular uptake, signal transduction, or adhesion through the organization of membrane microdomains. Several blood groups can modify the innate immune response to infection. Several distinct phenotypes associated with increased host resistance to malaria are overrepresented in populations living in areas where malaria is endemic, as a result of evolutionary pressures. Microorganisms can also stimulate antibodies against blood group antigens, including ABO, T, and Kell. Finally, there is a symbiotic relationship between blood group expression and maturation of the gastrointestinal microbiome.

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Metadata

Authors
Cooling, L.
Venue
Clinical Microbiology Reviews
Published
2015-07
Volume
28
Issue
3
Pages
801-870
ISSN
  • 0893-8512 (ISSN-L)
  • 1098-6618
OpenAlex
W1865473340
Cited by
632
References
13
FWCI
13.79
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Blood Groups in Infection and Host Susceptibility. https://app.cochat.ai/papers/10.1128/cmr.00109-14
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Cooling, L. (2015). Blood Groups in Infection and Host Susceptibility. Clinical Microbiology Reviews. https://doi.org/10.1128/cmr.00109-14

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.