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Candida parapsilosis: from Genes to the Bedside
Open accessAbstract
Patients with suppressed immunity are at the highest risk for hospital-acquired infections. Among these, invasive candidiasis is the most prevalent systemic fungal nosocomial infection.
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“Patients subjected to bone marrow transplantation usually have a central venous catheter, and those subjected to oral and gastrointestinal mucosal disorders and neutropenia are treated using total parenteral nutrition, which is one of the risk factors for candidemia caused by C. parapsilosis.30”
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Structural characterization and inhibition of carbonic anhydrase from Candida parapsilosis
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Metadata
- Authors
- Tóth, R., Nosek, J., Mora-Montes, H. M., Gabaldon, T., Bliss, J. M., Nosanchuk, J. D., Turner, S. A., Butler, G., Vágvölgyi, C., & Gácser, A.
- Affiliations
- University of Szeged (HU)
- Comenius University Bratislava (SK)
- Departamento de Biología, Universidad de Guanajuato, Guanajuato, Mexico
- Centre for Genomic Regulation, Barcelona Institute of Science and Technology, Barcelona, Spain
- Brown University (US)
- Albert Einstein College of Medicine (US)
- University College Dublin (IE)
- ORCID
- Venue
- Clinical Microbiology Reviews
- Publisher
- American Society for Microbiology
- Published
- 2019-03-20
- Volume
- 32
- Issue
- 2
- ISSN
- 0893-8512 (ISSN-L)
- 1098-6618
- PMC
- PMC6431126
- OpenAlex
- W2917995335
- Cited by
- 327
- References
- 383
- Citations by year
- 2026: 30 · 2025: 44 · 2024: 42 · 2023: 57 · 2022: 57 · 2021: 43 · 2020: 44 · 2019: 10
- FWCI
- 5.39
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Clinical Microbiology Reviews (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- SZTE Publicatio Repozitórium (University of Szeged) (acceptedVersion)
- Repository of the Academy's Library (Library of the Hungarian Academy of Sciences) (acceptedVersion)
- Funders
- Red Tematica Glicociencia en Salud (CONACYT-Mexico)
- Institutional Development Award (IDeA) NHI (P30GM114750)
- Slovak Research and Development Agency (APVV-14-0253)
- Slovak Grant Agency (VEGA 1/0333/15)
- Hungarian Academy of Sciences (LP2018-15/2018)
- NKFIH (K 123952)
- GINOP (GINOP2-3-2-15-2016-00015, GINOP 2.3.3-15-2016-00006)
- Ministry of Human Capacities (20391-3/2018/FEKUSTRAT)
- Consejo de Nacional de Ciencia y Tecnologia Mexico (PDCPN2014-247109, FC 2015-02-834)
- Science Foundation Ireland (12/IA/1343)
- HHS | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (R21HD089278)
- Universidad de Guanajuato (CIIC 95/2018)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Life Sciences › Immunology and Microbiology › Microbiology › Yeasts and Rust Fungi Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Fungal and yeast genetics research
- Keywords
- Candida parapsilosis, pathogenesis, virulence factors, transcriptomics, host immune response, antifungal susceptibility, clinical incidence
- MeSH terms
- Candida parapsilosis, Antifungal Agents, Candidiasis, Cross Infection, Humans, Microbial Sensitivity Tests, Incidence, Sequence Analysis, DNA, Sequence Analysis, RNA, Gene Expression Profiling
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