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The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.

Clinical and Laboratory Features of the Nocardia spp. Based on Current Molecular Taxonomy

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Brown-Elliott, Barbara A., Brown, June M., Conville, Patricia S., Wallace, Richard J.·2006·Clinical Microbiology Reviews

Abstract

SUMMARY: The recent explosion of newly described species of Nocardia results from the impact in the last decade of newer molecular technology, including PCR restriction enzyme analysis and 16S rRNA sequencing. These molecular techniques have revolutionized the identification of the nocardiae by providing rapid and accurate identification of recognized nocardiae and, at the same time, revealing new species and a number of yet-to-be-described species. There are currently more than 30 species of nocardiae of human clinical significance, with the majority of isolates being N. nova complex,N. abscessus,N. transvalensis complex,N. farcinica,N. asteroides type VI (N. cyriacigeorgica), and N. brasiliensis. These species cause a wide variety of diseases and have variable drug susceptibilities. Accurate identification often requires referral to a reference laboratory with molecular capabilities, as many newer species are genetically distinct from established species yet have few or no distinguishing phenotypic characteristics. Correct identification is important in deciding the clinical relevance of a species and in the clinical management and treatment of patients with nocardial disease. This review characterizes the currently known pathogenic species of Nocardia, including clinical disease, drug susceptibility, and methods of identification.

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Metadata

Authors
Brown-Elliott, B. A., Brown, J. M., Conville, P. S., & Wallace, R. J.
Venue
Clinical Microbiology Reviews
Published
2006-04
Volume
19
Issue
2
Pages
259-282
ISSN
  • 0893-8512 (ISSN-L)
  • 1098-6618
OpenAlex
W2129706499
Cited by
1,119
References
41
FWCI
35.39
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Clinical and Laboratory Features of the Nocardia spp. Based on Current Molecular Taxonomy. https://app.cochat.ai/papers/10.1128/cmr.19.2.259-282.2006
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Brown-Elliott, B. A., Brown, J. M., Conville, P. S., & Wallace, R. J. (2006). Clinical and Laboratory Features of the Nocardia spp. Based on Current Molecular Taxonomy. Clinical Microbiology Reviews. https://doi.org/10.1128/cmr.19.2.259-282.2006

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