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Cited by 81Safe Handling of Antineoplastic DrugsChemical Safety and Risk ManagementInfection Control in Healthcare

The DOI matches its Crossref record; 149 of the 149 references it cites were found in a registry or an index.

Biological safety cabinetry

Open access
Kruse, R H, Puckett, W H, Richardson, J H·1991·Clinical Microbiology Reviews
DOI 10.1128/cmr.4.2.207PMC PMC358192
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Abstract

The biological safety cabinet is the one piece of laboratory and pharmacy equipment that provides protection for personnel, the product, and the environment. Through the history of laboratory-acquired infections from the earliest published case to the emergence of hepatitis B and AIDS, the need for health care worker protection is described. A brief description with design, construction, function, and production capabilities is provided for class I and class III safety cabinets. The development of the high-efficiency particulate air filter provided the impetus for clean room technology, from which evolved the class II laminar flow biological safety cabinet. The clean room concept was advanced when the horizontal airflow clean bench was manufactured; it became popular in pharmacies for preparing intravenous solutions because the product was protected. However, as with infectious microorganisms and laboratory workers, individual sensitization to antibiotics and the advent of hazardous antineoplastic agents changed the thinking of pharmacists and nurses, and they began to use the class II safety cabinet to prevent adverse personnel reactions to the drugs. How the class II safety cabinet became the mainstay in laboratories and pharmacies is described, and insight is provided into the formulation of National Sanitation Foundation standard number 49 and its revisions. The working operations of a class II cabinet are described, as are the variations of the four types with regard to design, function, air velocity profiles, and the use of toxins. The main certification procedures are explained, with examples of improper or incorrect certifications. The required levels of containment for microorganisms are given. Instructions for decontaminating the class II biological safety cabinet of infectious agents are provided; unfortunately, there is no method for decontaminating the cabinet of antineoplastic agents.

Overview

Integrity signals

Registry

Crossref · 10.1128/cmr.4.2.207

Cites

149 of 149 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

The text we found for this paper looks like another document, so its claims and self-check weren’t run. The registry and citation checks still apply.

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The text we found for this paper looks like another document, so the self-check wasn’t run.

Citations

Cites

Research works printed but not linked: 4

  1. Grist N. R., Emslie J. A. Infections in British clinical laboratories, 1984-5. J Clin Pathol. 1987 Aug;40(8):826–829. doi: 10.1136/jcp.40.8.826. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI
  2. REITMAN M., WEDUM A. G. Microbiological safety. Public Health Rep. 1956 Jul;71(7):659–665. [PMC free article] [PubMed] [Google Scholar]
  3. SLEPUSHKIN A. N. Epidemiologicheskoe izuchenie sluchaev laboratornogo zarazheniia virusom venesuel'skogo entsefalomielita loshadei. Vopr Virusol. 1959 May-Jun;4(3):311–314. [PubMed] [Google Scholar]
  4. WEDUM A. G. Bacteriological safety. Am J Public Health Nations Health. 1953 Nov;43(11):1428–1437. doi: 10.2105/ajph.43.11.1428. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI

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Metadata

Authors
Kruse, R. H., Puckett, W. H., & Richardson, J. H.
Affiliations
MEDI, Inc., Lexington, Kentucky 40576-1486.
Venue
Clinical Microbiology Reviews
Publisher
American Society for Microbiology
Published
1991-04
Volume
4
Issue
2
Pages
207-241
ISSN
  • 0893-8512 (ISSN-L)
  • 1098-6618
DOI
10.1128/cmr.4.2.207
PMC
PMC358192
OpenAlex
W1912337695
Cited by
81
References
149
Citations by year
2026: 4 · 2025: 2 · 2024: 5 · 2023: 2 · 2022: 4 · 2021: 5 · 2020: 5 · 2019: 1 · 2017: 4 · 2016: 4 · 2015: 4 · 2014: 6 · 2013: 2 · 2012: 1
FWCI
1.63
Type
journal article
Language
en
Open access
Licence
journals.asm.org/non-commercial-tdm-license (tdm)
Locations
  • Clinical Microbiology Reviews (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Safe Handling of Antineoplastic Drugs
  • Physical Sciences › Chemical Engineering › Chemical Health and Safety › Chemical Safety and Risk Management
  • Health Sciences › Medicine › Infectious Diseases › Infection Control in Healthcare
Keywords
biological safety cabinet, laboratory-acquired infection, hepatitis B, AIDS, HEPA filters, pharmaceutical compounding, anticancer agents, air velocity profiles
MeSH terms
Acquired Immunodeficiency Syndrome, Atmosphere Exposure Chambers, Containment of Biohazards, Hepatitis B, Humans, Laboratory Infection, Tuberculosis

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

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Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.