Identification and Characterization of a Glycosyltransferase Involved in Acinetobacter baumannii Lipopolysaccharide Core Biosynthesis

Luke, Nicole R.; Sauberan, Shauna L.; Russo, Thomas A.; Beanan, Janet M.; Olson, Ruth; Loehfelm, Thomas W.; Cox, Andrew D.; St. Michael, Frank; Vinogradov, Evgeny V.; Campagnari, Anthony A.

doi:10.1128/iai.00016-10

Cited by 114Antibiotic Resistance in BacteriaBacterial Genetics and BiotechnologyBacterial Infections and Vaccines

The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.

Identification and Characterization of a Glycosyltransferase Involved in Acinetobacter baumannii Lipopolysaccharide Core Biosynthesis

Open access

Luke, Nicole R., Sauberan, Shauna L., Russo, Thomas A., Beanan, Janet M., Olson, Ruth, Loehfelm, Thomas W., Cox, Andrew D., St. Michael, Frank, Vinogradov, Evgeny V., Campagnari, Anthony A.·2010·Infection and Immunity

DOI 10.1128/iai.00016-10PMC PMC2863528

Open this paper in CoChat — free account

Abstract

Although Acinetobacter baumannii has emerged as a significant cause of nosocomial infections worldwide, there have been few investigations describing the factors important for A. baumannii persistence and pathogenesis. This paper describes the first reported identification of a glycosyltransferase, LpsB, involved in lipopolysaccharide (LPS) biosynthesis in A. baumannii . Mutational, structural, and complementation analyses indicated that LpsB is a core oligosaccharide glycosyl transferase. Using a genetic approach, lpsB was compared with the lpsB homologues of several A. baumannii strains. These analyses indicated that LpsB is highly conserved among A. baumannii isolates. Furthermore, we developed a monoclonal antibody, monoclonal antibody 13C11, which reacts to an LPS core epitope expressed by approximately one-third of the A. baumannii clinical isolates evaluated to date. Previous studies describing the heterogeneity of A. baumannii LPS were limited primarily to structural analyses; therefore, studies evaluating the correlation between these surface glycolipids and pathogenesis were warranted. Our data from an evaluation of LpsB mutant 307::TN17, which expresses a deeply truncated LPS glycoform consisting of only two 3-deoxy- d -manno-octulosonic acid residues and lipid A, suggest that A. baumannii LPS is important for resistance to normal human serum and confers a competitive advantage for survival in vivo . These results have important implications for the role of LPS in A. baumannii infections.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1128/iai.00016-10

Cites

45 of 45 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Bacterial genes for alpha-l-fucosidase, alpha-galactosidase and glycosyltransferases were enriched in non-responders.
“Using a new binning approach to focus on candidate bacterial driver genes, we observed enrichment of bacterial genes encoding key enzymes: polysaccharide deacetylase (associated with reduction of polysaccharide immunogenicity42) in Rs; and alpha-l-fucosidase45 and alpha-galactosidase46 (associated with mucus degradation) and glycosyltransferases (associated with LPS synthesis57) in NRs.”
From Intestinal microbiota signatures of clinical response and immune-related adverse events in melanoma patients treated with anti-PD-1 (2022) · cites this paper as [57]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Lipopolysaccharide endotoxins
Raetz, C. R. H., & Whitfield, C. (2002) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.71.110601.135414 · Cited by 4,404
Acinetobacter baumannii : Emergence of a Successful Pathogen
Peleg, A. Y., Seifert, H., & Paterson, D. L. (2008) · Clinical Microbiology Reviews · doi:10.1128/cmr.00058-07 · Cited by 3,402
Bacterial lipopolysaccharides : extraction with phenol-water and further applications of the procedure
Westphal, O. (1965) · Medical Entomology and Zoology · Cited by 2,533
The Epidemiology and Control of Acinetobacter baumannii in Health Care Facilities
Fournier, P., Richet, H., & Weinstein, R. A. (2006) · Clinical Infectious Diseases · doi:10.1086/500202 · Cited by 995
Antimicrobial Resistance: Acinetobacter baumannii: Epidemiology, Antimicrobial Resistance, and Treatment Options
Maragakis, L. L., & Perl, T. M. (2008) · Clinical Infectious Diseases · doi:10.1086/529198 · Cited by 972
Comparative Genome Sequence Analysis of Multidrug-Resistant Acinetobacter baumannii
Adams, M. D., Goglin, K. C., Molyneaux, N., Hujer, K. M., Lavender, H. F., Jamison, J. J., MacDonald, I. J., Martin, K. M., Russo, T. A., Campagnari, A. A., et al. (2008) · Journal of Bacteriology · doi:10.1128/jb.00834-08 · Cited by 434
Self-citation
An Outbreak of Multidrug-Resistant Acinetobacter baumannii-calcoaceticus Complex Infection in the US Military Health Care System Associated with Military Operations in Iraq
Scott, P. T., Deye, G. A., Srinivasan, A., Murray, C. K., Moran, K., Hulten, E. A., Fishbain, J. T., Craft, D. W., Riddell, S. W., Lindler, L., et al. (2007) · Clinical Infectious Diseases · doi:10.1086/518170 · Cited by 391
Multidrug-ResistantAcinetobacterExtremity Infections in Soldiers
Davis, K. A., Moran, K. A., McAllister, C. K., & Gray, P. J. (2005) · Emerging infectious diseases · doi:10.3201/1108.050103 · Cited by 327
Identification and Characterization of an Acinetobacter baumannii Biofilm-Associated Protein
Loehfelm, T. W., Luke, N. R., & Campagnari, A. A. (2007) · Journal of Bacteriology · doi:10.1128/jb.01416-07 · Cited by 283
Self-citation
Pseudomonas aeruginosa lipopolysaccharide: A major virulence factor, initiator of inflammation and target for effective immunity
Pier, G. B. (2007) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2007.03.012 · Cited by 258
Trauma-related Infections in Battlefield Casualties From Iraq
Petersen, K., Riddle, M. S., Danko, J., Blazes, D. L., Hayden, R. E., Tasker, S. A., & Dunne, J. R. (2007) · Annals of Surgery · doi:10.1097/01.sla.0000251707.32332.c1 · Cited by 221
Fulminant Community-Acquired Acinetobacter baumannii Pneumonia as a Distinct Clinical Syndrome
Leung, W., Chu, C., Tsang, K.-Y., Lo, F. H., Lo, K.-F., & Ho, P. (2006) · CHEST Journal · doi:10.1378/chest.129.1.102 · Cited by 188
Severe Community-Acquired Pneumonia due to Acinetobacter baumannii
Chen, M.-Z., Hsueh, P., Lee, L., Yu, C., Yang, P., & Luh, K. (2001) · CHEST Journal · doi:10.1378/chest.120.4.1072 · Cited by 185
Differential Roles of CD14 and Toll-like Receptors 4and 2 in Murine Acinetobacter Pneumonia
Knapp, S., Wieland, C. W., Florquin, S., Pantophlet, R. A., Dijkshoorn, L., Tshimbalanga, N., Akira, S., & van der Poll, T. (2005) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200505-730oc · Cited by 180
Identification of Acinetobacter Species and Genotyping of Acinetobacter baumannii by Multilocus PCR and Mass Spectrometry
Ecker, J. A., Massire, C., Hall, T. A., Ranken, R., Pennella, T.-T. D., Ivy, C. A., Blyn, L. B., Hofstadler, S. A., Endy, T. P., Scott, P. T., et al. (2006) · Journal of Clinical Microbiology · doi:10.1128/jcm.00619-06 · Cited by 163
Septic Complications of War Wounds
Tong, M. J. (1972) · JAMA · doi:10.1001/jama.1972.03190340050011 · Cited by 123
The long-distance tertiary air transfer and care of tsunami victims: Injury pattern and microbiological and psychological aspects*
Maegele, M., Gregor, S., Steinhausen, E. S., Bouillon, B., Heiss, M. M., Perbix, W., Wappler, F., Rixen, D., Geisen, J., Berger-Schreck, B., et al. (2005) · Critical Care Medicine · doi:10.1097/01.ccm.0000163269.42524.50 · Cited by 121
Acinetobacter baumannii lipopolysaccharides are potent stimulators of human monocyte activation via Toll-like receptor 4 signalling
Erridge, C., Moncayo-Nieto, O. L., Morgan, R., Young, M., & Poxton, I. R. (2007) · Journal of Medical Microbiology · doi:10.1099/jmm.0.46823-0 · Cited by 108
Penicillin‐Binding Protein 7/8 Contributes to the Survival ofAcinetobacter baumanniiIn Vitro and In Vivo
Russo, T. A., MacDonald, U., Beanan, J. M., Olson, R., MacDonald, I. J., Sauberan, S. L., Luke, N. R., Schultz, L. W., & Umland, T. C. (2009) · The Journal of Infectious Diseases · doi:10.1086/596317 · Cited by 105
Self-citation
Atypical Infections in Tsunami Survivors
Garzoni, C., Emonet, S., Legout, L., Benedict, R., Hoffmeyer, P. J., Bernard, L., & Garbino, J. (2005) · Emerging infectious diseases · doi:10.3201/eid1110.050715 · Cited by 93
Expression of Type IV Pili by Moraxella catarrhalis Is Essential for Natural Competence and Is Affected by Iron Limitation
Luke, N. R., Howlett, A. J., Shao, J., & Campagnari, A. A. (2004) · Infection and Immunity · doi:10.1128/iai.72.11.6262-6270.2004 · Cited by 78
Self-citation
Nosocomial Infections Caused by Acinetobacter baumannii A Major Threat Worldwide
Richet, H., & Fournier, P. (2006) · Infection Control and Hospital Epidemiology · doi:10.1086/505900 · Cited by 73
Rat Pneumonia and Soft-Tissue Infection Models for the Study of Acinetobacter baumannii Biology
Russo, T. A., Beanan, J. M., Olson, R., MacDonald, U., Luke, N. R., Gill, S. R., & Campagnari, A. A. (2008) · Infection and Immunity · doi:10.1128/iai.00269-08 · Cited by 63
Self-citation
Pasteurella multocida Expresses Two Lipopolysaccharide Glycoforms Simultaneously, but Only a Single Form Is Required for Virulence: Identification of Two Acceptor-Specific Heptosyl I Transferases
Harper, M., Boyce, J. D., Cox, A. D., Michael, F. S., Wilkie, I. W., Blackall, P. J., & Adler, B. (2007) · Infection and Immunity · doi:10.1128/iai.00212-07 · Cited by 63
Self-citation
Lipopolysaccharide in bacterial chronic infection: Insights from Helicobacter pylori lipopolysaccharide and lipid A
MORAN, A. (2007) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2007.03.008 · Cited by 59
Structural analysis of the lipopolysaccharide of Pasteurella multocida strain VP161: identification of both Kdo-P and Kdo–Kdo species in the lipopolysaccharide
Michael, F. S., Li, J., VINOGRADOV, E. V., Larocque, S., Harper, M., & Cox, A. D. (2004) · Carbohydrate Research · doi:10.1016/j.carres.2004.10.017 · Cited by 59
Self-citation
Outer membrane protein B1, an iron-repressible protein conserved in the outer membrane of Moraxella (Branhamella) catarrhalis, binds human transferrin
Campagnari, A. A., Ducey, T. F., & Rebmann, C. A. (1996) · Infection and Immunity · doi:10.1128/iai.64.9.3920-3924.1996 · Cited by 58
Self-citation
Why are we afraid of Acinetobacter baumannii?
Pérez, F., Endimiani, A., & Bonomo, R. A. (2008) · Expert Review of Anti-infective Therapy · doi:10.1586/14787210.6.3.269 · Cited by 54
Comparative and Genetic Analyses of the Putative Vibrio cholerae Lipopolysaccharide Core Oligosaccharide Biosynthesis ( wav ) Gene Cluster
Nesper, J., Kraiß, A., Schild, S., Blaβ, J., Klose, K. E., Bockemühl, J., & Reidl, J. (2002) · Infection and Immunity · doi:10.1128/iai.70.5.2419-2433.2002 · Cited by 53
Structural and serological characterisation of the O-antigenic polysaccharide of the lipopolysaccharide from Acinetobacter baumannii strain 24
VINOGRADOV, E. V., Brade, L., Brade, H., & Holst, O. (2003) · Carbohydrate Research · doi:10.1016/j.carres.2003.05.001 · Cited by 50
Self-citation
Sequence and organization of pMAC, an Acinetobacter baumannii plasmid harboring genes involved in organic peroxide resistance
Dorsey, C. W., Tomaras, A. P., & Actis, L. A. (2006) · Plasmid · doi:10.1016/j.plasmid.2006.01.004 · Cited by 50
The structure of the carbohydrate backbone of the lipopolysaccharide from Acinetobacter baumannii strain ATCC 19606
VINOGRADOV, E. V., Duus, J. Ø., Brade, H., & Holst, O. (2002) · European Journal of Biochemistry · doi:10.1046/j.0014-2956.2001.02647.x · Cited by 46
Self-citation
Identification of a 3-Deoxy- d - manno -Octulosonic Acid Biosynthetic Operon in Moraxella catarrhalis and Analysis of a KdsA-Deficient Isogenic Mutant
Luke, N. R., Allen, S., Gibson, B. W., & Campagnari, A. A. (2003) · Infection and Immunity · doi:10.1128/iai.71.11.6426-6434.2003 · Cited by 38
Self-citation
Characterization of a Novel Branched Tetrasaccharide of 3-Deoxy-d-manno-oct-2-ulopyranosonic Acid
VINOGRADOV, E. V., Petersen, B. O., THOMAS‐OATES, J. E., Duus, J. Ø., Brade, H., & Holst, O. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.43.28122 · Cited by 37
Self-citation
Relationship of the Lipopolysaccharide Structure of Yersinia bpestis to Resistance to Antimicrobial Factors
Knirel, Y. A., Kocharova, N. A., Титарева, Г. М., Викторовна, Б. И., Senchenkova, S. N., Bystrova, O. V., Dentovskaya, S. V., Anisimov, A. P., Pier, G. B., Lindner, B., et al. (2007) · Advances in experimental medicine and biology · doi:10.1007/978-0-387-72124-8_7 · Cited by 36
Genetic Characterization of a Sinorhizobium meliloti Chromosomal Region Involved in Lipopolysaccharide Biosynthesis
Lagares, A., Hozbor, D. F., Niehaus, K., Otero, A. J. L. P., Lorenzen, J., Arnold, W., & Pühler, A. (2001) · Journal of Bacteriology · doi:10.1128/jb.183.4.1248-1258.2001 · Cited by 35
The structure of the polysaccharide O-chain of the LPS from Acinetobacter baumannii strain ATCC 17961
MacLean, L. L., Perry, M. B., Chen, W., & VINOGRADOV, E. V. (2009) · Carbohydrate Research · doi:10.1016/j.carres.2008.12.026 · Cited by 27
Self-citation
Effect of EDTA on the resistance of clinical isolates of Acinetobacter baumannii to the bactericidal activity of normal human serum
García, A., SOLAR, H., González, C., & Raúl Zemelman, Z. (2000) · Journal of Medical Microbiology · doi:10.1099/0022-1317-49-11-1047 · Cited by 22
Identification of Acinetobacter baumannii Strains with Monoclonal Antibodies against the O Antigens of Their Lipopolysaccharides
Pantophlet, R. A., Brade, L., & Brade, H. (1999) · Clinical and Diagnostic Laboratory Immunology · doi:10.1128/cdli.6.3.323-329.1999 · Cited by 22
O-Antigen Diversity among Acinetobacter baumannii Strains from the Czech Republic and Northwestern Europe, as Determined by Lipopolysaccharide-Specific Monoclonal Antibodies
Pantophlet, R. A., Nemec, A., Brade, L., Brade, H., & Dijkshoorn, L. (2001) · Journal of Clinical Microbiology · doi:10.1128/jcm.39.7.2576-2580.2001 · Cited by 21
A unique glycosyltransferase involved in the initial assembly of Moraxella catarrhalis lipooligosaccharides
Schwingel, J. M., Michael, F. S., Cox, A. D., Masoud, H., Richards, J. C., & Campagnari, A. A. (2008) · Glycobiology · doi:10.1093/glycob/cwn021 · Cited by 15
Self-citation
The symbiotic defect in a Sinorhizobium meliloti lipopolysaccharide mutant can be overcome by expression of other surface polysaccharides
Hozbor, D. F., Otero, A. J. L. P., Lodeiro, A. R., Papa, M. F. D., Pistorio, M., & Lagares, A. (2004) · Research in Microbiology · doi:10.1016/j.resmic.2004.06.012 · Cited by 11
Generation and Serological Characterization of Murine Monoclonal Antibodies against O Antigens from Acinetobacter Reference Strains
Pantophlet, R. A., Brade, L., & Brade, H. (2001) · Clinical and Diagnostic Laboratory Immunology · doi:10.1128/cdli.8.4.825-827.2001 · Cited by 8
Periodate oxidation of R36A pneumococci greatly enhances production of hybridomas secreting anti-protein antibodies
Casal, J., Jado, I., Fenoll, A., Pérez, A., & Toraño, A. (1998) · Microbial Pathogenesis · doi:10.1006/mpat.1997.0175 · Cited by 6
Structural and serological characterisation of the O-antigenic polysaccharide of the lipopolysaccharide from Acinetobacter strain 96 (DNA group 11)
VINOGRADOV, E. V., Pantophlet, R. A., Brade, H., & Holst, O. (2001) · Journal of Endotoxin Research · doi:10.1177/09680519010070020501 · Cited by 6
Self-citation

Flagged first, then by citations

Sorted by citations

Clinical and Pathophysiological Overview of Acinetobacter Infections: a Century of Challenges
Wong, D. W., Nielsen, T. B., Bonomo, R. A., Pantapalangkoor, P., Luna, B. M., & Spellberg, B. J. (2017) · Clinical Microbiology Reviews · doi:10.1128/cmr.00058-16 · Cited by 1,185
Biology of Acinetobacter baumannii: Pathogenesis, Antibiotic Resistance Mechanisms, and Prospective Treatment Options
Lee, C.-R., Lee, J. H., Park, M., Park, K. S., Bae, I. K., Kim, Y. B., Cha, C., Jeong, B. C., & Lee, S. H. (2017) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2017.00055 · Cited by 1,019
Acinetobacter baumannii Antibiotic Resistance Mechanisms
Kyriakidis, I., Vasileiou, E., Pana, Z. D., & Tragiannidis, A. (2021) · Pathogens · doi:10.3390/pathogens10030373 · Cited by 773
Antibiotic Modulation of Capsular Exopolysaccharide and Virulence in Acinetobacter baumannii
Geisinger, E., & Isberg, R. R. (2015) · PLoS Pathogens · doi:10.1371/journal.ppat.1004691 · Cited by 544
Acinetobacter baumannii : human infections, factors contributing to pathogenesis and animal models
McConnell, M. J., Actis, L. A., & Pachón, J. (2012) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2012.00344.x · Cited by 543
Intestinal microbiota signatures of clinical response and immune-related adverse events in melanoma patients treated with anti-PD-1
McCulloch, J. A., Davar, D., Rodrigues, R. R., Badger, J. H., Fang, J. R., Cole, A. M., Balaji, A. K., Vetizou, M., Prescott, S. M., Fernandes, M. R., et al. (2022) · Nature Medicine · doi:10.1038/s41591-022-01698-2 · Cited by 472
Acinetobacter baumannii Biofilm Formation and Its Role in Disease Pathogenesis: A Review
Gedefie, A., Demsiss, W., Belete, M. A., Kassa, Y., Tesfaye, M., Tilahun, M., Bisetegn, H., & Sahle, Z. (2021) · Infection and Drug Resistance · doi:10.2147/idr.s332051 · Cited by 358
The K1 Capsular Polysaccharide of Acinetobacter baumannii Strain 307-0294 Is a Major Virulence Factor
Russo, T. A., Luke, N. R., Beanan, J. M., Olson, R., Sauberan, S. L., MacDonald, U., Schultz, L. W., Umland, T. C., & Campagnari, A. A. (2010) · Infection and Immunity · doi:10.1128/iai.00366-10 · Cited by 327
Self-citation
Acinetobacter baumannii: Evolution of Antimicrobial Resistance—Treatment Options
Murray, G. L., Peleg, A. Y., & Doi, Y. (2015) · Seminars in Respiratory and Critical Care Medicine · doi:10.1055/s-0034-1398388 · Cited by 315
Acinetobacter baumannii Resistance: A Real Challenge for Clinicians
Vázquez-López, R., Solano, S., Whaley, J. J. J., Vaamonde, J. A. A., Alonzo, L. A. P., Reséndiz, A. R., Álvarez, M. M., López, E. N. V., Kelly, G. A. F., Álvarez-Hernández, D.-A., et al. (2020) · Antibiotics · doi:10.3390/antibiotics9040205 · Cited by 297
The Acinetobacter baumannii Biofilm-Associated Protein Plays a Role in Adherence to Human Epithelial Cells
Stoos, K. B., & Campagnari, A. A. (2011) · Infection and Immunity · doi:10.1128/iai.05913-11 · Cited by 268
Self-citation
Genome-wide identification of Acinetobacter baumannii genes necessary for persistence in the lung
Wang, N., Ozer, E. A., Mandel, M. J., & Hauser, A. R. (2014) · mBio · doi:10.1128/mbio.01163-14 · Cited by 234
Reinforcing Lipid A Acylation on the Cell Surface of Acinetobacter baumannii Promotes Cationic Antimicrobial Peptide Resistance and Desiccation Survival
Boll, J. M., Tucker, A. T., Klein, D. R., Beltran, A. M., Brodbelt, J. S., Davies, B. W., & Trent, M. S. (2015) · mBio · doi:10.1128/mbio.00478-15 · Cited by 207
Insights into Acinetobacter baumannii pathogenicity
Cerqueira, G. M., & Peleg, A. Y. (2011) · IUBMB Life · doi:10.1002/iub.533 · Cited by 192
Personalized Therapeutic Cocktail of Wild Environmental Phages Rescues Mice from Acinetobacter baumannii Wound Infections
Regeimbal, J. M., Jacobs, A. C., Corey, B. W., Henry, M. S., Thompson, M. G., Pavlicek, R. L., Quinones, J., Hannah, R. M., Ghebremedhin, M., Crane, N. J., et al. (2016) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02877-15 · Cited by 188
Diversity and Function of Capsular Polysaccharide in Acinetobacter baumannii
Singh, J. K., Adams, F. G., & Brown, M. H. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.03301 · Cited by 186
The Success of Acinetobacter Species; Genetic, Metabolic and Virulence Attributes
Peleg, A. Y., de Breij, A., Adams, M. D., Cerqueira, G. M., Mocali, S., Galardini, M., Nibbering, P. H., Earl, A. M., Ward, D. V., Paterson, D. L., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0046984 · Cited by 182
A common pathway for O ‐linked protein‐glycosylation and synthesis of capsule in A cinetobacter baumannii
Lees‐Miller, R. G., Iwashkiw, J. A., Scott, N. E., Seper, A., VINOGRADOV, E. V., Schild, S., & Feldman, M. F. (2013) · Molecular Microbiology · doi:10.1111/mmi.12300 · Cited by 166
Self-citation
The K1 Capsular Polysaccharide from Acinetobacter baumannii Is a Potential Therapeutic Target via Passive Immunization
Russo, T. A., Beanan, J. M., Olson, R., MacDonald, U., Cox, A. D., Michael, F. S., VINOGRADOV, E. V., Spellberg, B. J., Luke‐Marshall, N. R., & Campagnari, A. A. (2013) · Infection and Immunity · doi:10.1128/iai.01184-12 · Cited by 157
Self-citation
Carbapenem resistance inAcinetobacter baumannii: laboratory challenges, mechanistic insights and therapeutic strategies
Abbott, I. J., Cerqueira, G. M., Bhuiyan, S., & Peleg, A. Y. (2013) · Expert Review of Anti-infective Therapy · doi:10.1586/eri.13.21 · Cited by 147
Mapping Global Prevalence of Acinetobacter baumannii and Recent Vaccine Development to Tackle It
Ma, C., & McClean, S. (2021) · Vaccines · doi:10.3390/vaccines9060570 · Cited by 154
Acinetobacter baumannii: biology and drug resistance — role of carbapenemases
Nowak, P., & Paluchowska, P. (2015) · Folia Histochemica et Cytobiologica · doi:10.5603/fhc.a2016.0009 · Cited by 145
A Mouse Model of Acinetobacter baumannii-Associated Pneumonia Using a Clinically Isolated Hypervirulent Strain
Harris, G., Lee, R. K., Lam, C. K., Kanzaki, G., Patel, G. B., Xu, H. H., & Chen, W. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00944-13 · Cited by 138
Pathogenic Acinetobacter: from the Cell Surface to Infinity and Beyond
Weber, B. S., Harding, C. M., & Feldman, M. F. (2015) · Journal of Bacteriology · doi:10.1128/jb.00906-15 · Cited by 127
Comparative analysis of surface-exposed virulence factors of Acinetobacter baumannii
Eijkelkamp, B. A., Stroeher, U. H., Hassan, K. A., Paulsen, I. T., & Brown, M. H. (2014) · BMC Genomics · doi:10.1186/1471-2164-15-1020 · Cited by 122
Acinetobacter baumannii: Envelope Determinants That Control Drug Resistance, Virulence, and Surface Variability
Geisinger, E., Huo, W., Hernandez-Bird, J., & Isberg, R. R. (2019) · Annual Review of Microbiology · doi:10.1146/annurev-micro-020518-115714 · Cited by 118
A global regulatory system links virulence and antibiotic resistance to envelope homeostasis in Acinetobacter baumannii
Geisinger, E., Mortman, N. J., Vargas-Cuebas, G. G., Tai, A., & Isberg, R. R. (2018) · PLoS Pathogens · doi:10.1371/journal.ppat.1007030 · Cited by 117
H-NS Plays a Role in Expression of Acinetobacter baumannii Virulence Features
Eijkelkamp, B. A., Stroeher, U. H., Hassan, K. A., Elbourne, L. D. H., Paulsen, I. T., & Brown, M. H. (2013) · Infection and Immunity · doi:10.1128/iai.00065-13 · Cited by 112
Innate Immune Responses to Systemic Acinetobacter baumannii Infection in Mice: Neutrophils, but Not Interleukin-17, Mediate Host Resistance
Deckman, J. M., Meissler, J. J., Robinson, R. H., Spence, P. B., Truant, A., Gaughan, J. P., & Eisenstein, T. K. (2011) · Infection and Immunity · doi:10.1128/iai.00069-11 · Cited by 99
Antibiotic susceptibility signatures identify potential antimicrobial targets in the Acinetobacter baumannii cell envelope
Geisinger, E., Mortman, N. J., Dai, Y., Cokol, M., Syal, S., Farinha, A., Fisher, D. G., Tang, A. Y., Lazinski, D. W., Wood, S. J., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-18301-2 · Cited by 97
Carbapenem-resistant Acinetobacter baumannii raises global alarm for new antibiotic regimens
Thacharodi, A., Vithlani, A., Hassan, S., Alqahtani, A., & Pugazhendhi, A. (2024) · iScience · doi:10.1016/j.isci.2024.111367 · Cited by 98
Pan-Genome Plasticity and Virulence Factors: A Natural Treasure Trove for Acinetobacter baumannii
Karampatakis, T., Tsergouli, K., & Behzadi, P. (2024) · Antibiotics · doi:10.3390/antibiotics13030257 · Cited by 98
The Response Regulator BfmR Is a Potential Drug Target for Acinetobacter baumannii
Russo, T. A., Manohar, A., Beanan, J. M., Olson, R., MacDonald, U., Graham, J., & Umland, T. C. (2016) · mSphere · doi:10.1128/msphere.00082-16 · Cited by 92
Self-citation
Chromosomally encoded and plasmid-mediated polymyxins resistance in Acinetobacter baumannii: a huge public health threat
Lima, W. G., Alves, M. C., Nizer, W. S. D. C., & de Paiva, M. C. (2018) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-018-3223-9 · Cited by 89
Host-microbe interactions that shape the pathogenesis ofAcinetobacter baumanniiinfection
Mortensen, B. L., & Skaar, E. P. (2012) · Cellular Microbiology · doi:10.1111/j.1462-5822.2012.01817.x · Cited by 88
Extracellular stress and lipopolysaccharide modulate Acinetobacter baumannii surface-associated motility
McQueary, C. N., Kirkup, B. C., Si, Y., Barlow, M., Actis, L. A., Craft, D. W., & Zurawski, D. V. (2012) · The Journal of Microbiology · doi:10.1007/s12275-012-1555-1 · Cited by 83
Genetic Determinants of Intrinsic Colistin Tolerance in Acinetobacter baumannii
Hood, M. I., Becker, K. W., Roux, C. M., Dunman, P. M., & Skaar, E. P. (2012) · Infection and Immunity · doi:10.1128/iai.00704-12 · Cited by 81
Recent advances in biosensor based diagnosis of urinary tract infection
Kumar, M., Ghosh, S., Nayak, S., & Das, A. P. (2016) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2016.02.023 · Cited by 64
Variation in the OC Locus of Acinetobacter baumannii Genomes Predicts Extensive Structural Diversity in the Lipooligosaccharide
Kenyon, J. J., Nigro, S. J., & Hall, R. M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0107833 · Cited by 62
Code blue: A cinetobacter baumannii, a nosocomial pathogen with a role in the oral cavity
Richards, A. M., Kwaik, Y. A., & Lamont, R. J. (2014) · Molecular Oral Microbiology · doi:10.1111/omi.12072 · Cited by 63
Platelet-activating Factor Receptor Initiates Contact of Acinetobacter baumannii Expressing Phosphorylcholine with Host Cells
Smani, Y., Docobo-Pérez, F., López-Rojas, R., Domínguez-Herrera, J., Ibáñez-Martínez, J., & Pachón, J. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.344556 · Cited by 62
Modulation of virulence in Acinetobacter baumannii cells surviving photodynamic treatment with toluidine blue
Pourhajibagher, M., Boluki, E., Chiniforush, N., Pourakbari, B., Farshadzadeh, Z., Ghorbanzadeh, R., Azimzadeh, M., & Bahador, A. (2016) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2016.07.007 · Cited by 59
Eradication of multidrug-resistant Acinetobacter baumannii from the respiratory tract with inhaled colistin methanesulfonate: a matched case-control study
Kuo, S., Lee, Y.-T., Yang, S.-P., Chen, C.-P., Chen, T.-L., Hsieh, S.-L., Siu, L.-K. K., & Fung, C. (2011) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2011.03682.x · Cited by 58
Global Gene Expression Profile of Acinetobacter baumannii During Bacteremia
Murray, G. L., Tsyganov, K., Kostoulias, X., Bulach, D., Powell, D., Creek, D. J., Boyce, J. D., Paulsen, I. T., & Peleg, A. Y. (2016) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiw529 · Cited by 58
Bloodstream infections caused by ST2 Acinetobacter baumannii: risk factors, antibiotic regimens, and virulence over 6 years period in China
Yu, K., Zeng, W., Xu, Y., Liao, W., Xu, W., Zhou, T., Cao, J., & Chen, L. (2021) · Antimicrobial Resistance and Infection Control · doi:10.1186/s13756-020-00876-6 · Cited by 57
Characterization of theAcinetobacter baumanniigrowth phase-dependent and serum responsive transcriptomes
Jacobs, A. C., Sayood, K., Olmsted, S. B., Blanchard, C. E., Hinrichs, S. H., Russell, D. J., & Dunman, P. M. (2011) · FEMS Immunology & Medical Microbiology · doi:10.1111/j.1574-695x.2011.00926.x · Cited by 56
Intracellular Trafficking and Persistence of Acinetobacter baumannii Requires Transcription Factor EB
Parra-Millán, R., Guerrero‐Gómez, D., Ayerbe-Algaba, R., Pachón-Ibáñez, M. E., Miranda‐Vizuete, A., Pachón, J., & Smani, Y. (2018) · mSphere · doi:10.1128/msphere.00106-18 · Cited by 58
Multisystem combined uranium resistance mechanisms and bioremediation potential of Stenotrophomonas bentonitica BII-R7: Transcriptomics and microscopic study
Pinel-Cabello, M., Jroundi, F., López-Fernández, M., Geffers, R., Jarek, M., Jáuregui, R., Link, A., Vilchez‐Vargas, R., & Merroun, M. L. (2020) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2020.123858 · Cited by 53
Acinetobacter baumannii : Virulence Strategies and Host Defense Mechanisms
Tiku, V. (2021) · DNA and Cell Biology · doi:10.1089/dna.2021.0588 · Cited by 51
An Explorative Review on Advanced Approaches to Overcome Bacterial Resistance by Curbing Bacterial Biofilm Formation
Mohamad, F., Alzahrani, R. R., Alsaadi, A., Alrfaei, B. M., Yassin, A. E. B., Alkhulaifi, M. M., & Halwani, M. (2023) · Infection and Drug Resistance · doi:10.2147/idr.s380883 · Cited by 55
Colistin-Resistant Acinetobacter baumannii Clinical Strains with Deficient Biofilm Formation
Dafopoulou, K., Xavier, B. B., Hotterbeekx, A., Janssens, L., Lammens, C., Dé, E., Goossens, H., Tsakris, A., Malhotra‐Kumar, S., & Pournaras, S. (2015) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02518-15 · Cited by 50
A medically relevant capsular polysaccharide in Acinetobacter baumannii is a potential vaccine candidate
Yang, F., Lou, T.-C., Kuo, S., Wu, W., Chern, J., Lee, Y., Chen, S., Zou, W., Lin, N., & Wu, S. (2017) · Vaccine · doi:10.1016/j.vaccine.2017.01.060 · Cited by 48
Use of a stainless steel washer platform to study Acinetobacter baumannii adhesion and biofilm formation on abiotic surfaces
Orsinger-Jacobsen, S. J., Patel, S. S., Vellozzi, E. M., Gialanella, P., Nimrichter, L., de Miranda, K. R., & Martinez, L. R. (2013) · Microbiology · doi:10.1099/mic.0.068825-0 · Cited by 45
Facts and Hopes for Gut Microbiota Interventions in Cancer Immunotherapy
Davar, D., & Zarour, H. M. (2022) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-21-1129 · Cited by 40
Metagenomic Analysis Reveals a Changing Microbiome Associated With the Depth of Invasion of Oral Squamous Cell Carcinoma
Liu, Y., Li, Z., Qi, Y., Wen, X., & Zhang, L. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.795777 · Cited by 44
The role of TonB-dependent copper receptor in virulence of Acinetobacter baumannii
Abdollahi, S., Rasooli, I., & Gargari, S. L. M. (2018) · Infection Genetics and Evolution · doi:10.1016/j.meegid.2018.03.001 · Cited by 40
Exposure to Nanoplastic Particles Enhances Acinetobacter Survival, Biofilm Formation, and Serum Resistance
Tang, M., Ding, G., Lu, X., Huang, Q., Du, H., Xiao, G., & Wang, D. (2022) · Nanomaterials · doi:10.3390/nano12234222 · Cited by 37
Systematic analyses identify modes of action of ten clinically relevant biocides and antibiotic antagonism in Acinetobacter baumannii
Li, L., Short, F. L., Hassan, K. A., Naidu, V., Pokhrel, A., Nagy, S. S., Prity, F. T., Shah, B. S., Afrin, N., Baker, S. G., et al. (2023) · Nature Microbiology · doi:10.1038/s41564-023-01474-z · Cited by 37
Outer Membrane Vesicles from Acinetobacter baumannii: Biogenesis, Functions, and Vaccine Application
Weng, Z., Yang, N., Shi, S., Xu, Z., Chen, Z., Chen, L., Zhang, X., & Du, X. (2023) · Vaccines · doi:10.3390/vaccines12010049 · Cited by 39
Carbapenem-Resistant Acinetobacter baumannii: Virulence Factors, Molecular Epidemiology, and Latest Updates in Treatment Options
Karampatakis, T., Tsergouli, K., & Behzadi, P. (2025) · Microorganisms · doi:10.3390/microorganisms13091983 · Cited by 40
Antimicrobial Resistance in Romania: Updates on Gram-Negative ESCAPE Pathogens in the Clinical, Veterinary, and Aquatic Sectors
Barbu, I. C., Gheorghe-Barbu, I., Grigore, G. A., Vrâncianu, C. O., & Chifiriuc, M. C. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24097892 · Cited by 32
Lon Protease Has Multifaceted Biological Functions in Acinetobacter baumannii
Ching, C., Yang, B., Onwubueke, C., Lazinski, D. W., Camilli, A., & Godoy, V. G. (2018) · Journal of Bacteriology · doi:10.1128/jb.00536-18 · Cited by 31
Transcriptomic analysis of colistin-susceptible and colistin-resistant isolates identifies genes associated with colistin resistance in Acinetobacter baumannii
Park, Y. K., Lee, J.-Y., & Ko, K. S. (2015) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2015.04.009 · Cited by 30
Association of virulence gene expression with colistin-resistance in Acinetobacter baumannii: analysis of genotype, antimicrobial susceptibility, and biofilm formation
Bahador, A., Farshadzadeh, Z., Raoofian, R., Mokhtaran, M., Pourakbari, B., Pourhajibagher, M., & Hashemi, F. B. (2018) · Annals of Clinical Microbiology and Antimicrobials · doi:10.1186/s12941-018-0277-6 · Cited by 28
Understanding the biofilm development of Acinetobacter baumannii and novel strategies to combat infection
Pathoor, N. N., Viswanathan, A., Wadhwa, G., & Ganesh, P. S. (2024) · Apmis · doi:10.1111/apm.13399 · Cited by 27
Characterization of Highly Ferulate-Tolerant Acinetobacter baylyi ADP1 Isolates by a Rapid Reverse Engineering Method
Luo, J., McIntyre, E. A., Bedore, S. R., Santala, V. P., Neidle, E. L., & Santala, S. (2021) · Applied and Environmental Microbiology · doi:10.1128/aem.01780-21 · Cited by 22
Phenotypic and Genotypic Characterization of Acinetobacter spp. Panel Strains: A Cornerstone to Facilitate Antimicrobial Development
D’Souza, R., Pinto, N. A., Phuong, N. L., Higgins, P. G., Vu, T. N., Byun, J., Cho, Y. L., Choi, J. R., & Yong, D. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.00559 · Cited by 24
Emergence of multidrug-resistant Staphylococcus haemolyticus in neonatal intensive care unit in Southern France, a genomic study
Magnan, C., Morsli, M., Salipante, F., Thiry, B., Attar, J. E., Maio, M. D., Safaria, M., Tran, T.-A., Dunyach-Remy, C., Ory, J., et al. (2024) · Emerging Microbes & Infections · doi:10.1080/22221751.2024.2353291 · Cited by 24
Characterization of Acinetobacter baumannii core oligosaccharide synthesis reveals novel aspects of lipooligosaccharide assembly
VanOtterloo, L. M., Macias, L. A., Powers, M. J., Brodbelt, J. S., & Trent, M. S. (2024) · mBio · doi:10.1128/mbio.03013-23 · Cited by 24
Les misérables: a Parallel Between Antimicrobial Resistance and COVID-19 in Underdeveloped and Developing Countries
Jorge, G. P., Goes, I. C. R. D. S., & Gontijo, M. T. P. (2022) · Current Infectious Disease Reports · doi:10.1007/s11908-022-00788-z · Cited by 22
ESKAPE pathogens and associated quorum sensing systems: New targets for novel antimicrobials development
Aruwa, C. E., Chellan, T., S’thebe, N. W., Dweba, Y., & Sabiu, S. (2024) · Health Sciences Review · doi:10.1016/j.hsr.2024.100155 · Cited by 21
Co-Occurrence of blaOXA-23 in the Chromosome and Plasmid: Increased Fitness in Carbapenem-Resistant Acinetobacter baumannii
Wang, Z., Li, H., Zhang, J., & Wang, H. (2021) · Antibiotics · doi:10.3390/antibiotics10101196 · Cited by 20
Genetic Manipulation of Acinetobacter baumannii
Jacobs, A. C., Thompson, M. G., Gebhardt, M. J., Corey, B. W., Yıldırım, S., Shuman, H. A., & Zurawski, D. V. (2014) · Current Protocols in Microbiology · doi:10.1002/9780471729259.mc06g02s35 · Cited by 20
AbOmpA in Acinetobacter baumannii: exploring virulence mechanisms of outer membrane-integrated and outer membrane vesicle-associated AbOmpA and developing anti-infective agents targeting AbOmpA
Oh, M.-H., Islam, M. M., Kim, N., Choi, C. H., Shin, M., Shin, W. S., & Lee, J. C. (2025) · Journal of Biomedical Science · doi:10.1186/s12929-025-01147-5 · Cited by 19
Comparative analysis of prophage-like elements in Helicobacter sp. genomes
Fan, X., Li, Y., He, R., Li, Q., & He, W. (2016) · PeerJ · doi:10.7717/peerj.2012 · Cited by 19
RecA levels modulate biofilm development in Acinetobacter baumannii
Ching, C., Brychcy, M., Nguyen, B. H., Muller, P. A., Pearson, A. R., Downs, M. J., Regan, S., Isley, B. C., Fowle, W. H., Chai, Y., et al. (2023) · Molecular Microbiology · doi:10.1111/mmi.15188 · Cited by 20
Glucose Availability Enhances Lipopolysaccharide Production and Immunogenicity in the Opportunistic Pathogen Acinetobacter Baumannii
Rossi, E., Longo, F., Barbagallo, M., Peano, C., Consolandi, C., Pietrelli, A., Jaillon, S., Garlanda, C., & Landini, P. (2016) · Future Microbiology · doi:10.2217/fmb.15.153 · Cited by 18
The effect of antimicrobial photodynamic therapy against virulence genes expression in colistin-resistance Acinetobacter baumannii
Boluki, E., Moradi, M., Azar, P. S., Fekrazad, R., Pourhajibagher, M., & Bahador, A. (2019) · LASER THERAPY · doi:10.5978/islsm.28_19-or-03 · Cited by 17
Moraxella catarrhalis is susceptible to antimicrobial photodynamic therapy with Photofrin
Luke‐Marshall, N. R., Mang, T. S., Hansen, L. A., & Campagnari, A. A. (2014) · Lasers in Surgery and Medicine · doi:10.1002/lsm.22287 · Cited by 17
Self-citation
Global regulator DksA modulates virulence of Acinetobacter baumannii
Kim, N., Son, J. H., Kim, K., Kim, H. J., Kim, Y. J., Shin, M., & Lee, J. C. (2021) · Virulence · doi:10.1080/21505594.2021.1995253 · Cited by 16
Lipopolysaccharide structure modulates cationic biocide susceptibility and crystalline biofilm formation in Proteus mirabilis
Clarke, O. E., Pelling, H., Bennett, V., Matsumoto, T., Gregory, G. E., Nzakizwanayo, J., Slate, A. J., Preston, A., Laabei, M., Bock, L. J., et al. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1150625 · Cited by 16
RNA-Mediated cis Regulation in Acinetobacter baumannii Modulates Stress-Induced Phenotypic Variation
Ching, C., Gozzi, K., Heinemann, B., Chai, Y., & Godoy, V. G. (2017) · Journal of Bacteriology · doi:10.1128/jb.00799-16 · Cited by 15
Exploring Roles of the Polysaccharide Capsule in Pathogenesis of Hypervirulent Acinetobacter baumannii Clinical Isolate Lac-4
Bjånes, E., Koh, T., Qayum, T., Zurich, R. H., McCabe, S., Hampel, K., Morishita-Cartwright, L., & Nizet, V. (2023) · Antibiotics · doi:10.3390/antibiotics13010010 · Cited by 15
Acinetobacter baumannii as an oro-dental pathogen: a red alert!!
Girija, A. S. S. (2024) · Journal of Applied Oral Science · doi:10.1590/1678-7757-2023-0382 · Cited by 15
In Silico Identification of Probable Drug and Vaccine Candidates Against Antibiotic-Resistant Acinetobacter baumannii
Hosseingholi, E. Z., Zarrini, G., Pashazadeh, M., Hayat, S. M. G., & Molavi, G. (2020) · Microbial Drug Resistance · doi:10.1089/mdr.2019.0236 · Cited by 13
Intracellular Acinetobacter baumannii acts as a transient reservoir in lung infection via a “persist and resist” strategy
Janet-Maitre, M., Venanzio, G. D., Jackson-Litteken, C. D., Scott, N. E., & Feldman, M. F. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2511369122 · Cited by 13
Genetic polymorphisms of the CYP2E1 gene do not contribute to oral cancer susceptibility in south Indians.
Balaji, L., Singh, K. B., & Bhaskar, L. V. (2011) · PubMed · Cited by 12
Acinetobacter phages use distinct strategies to breach the capsule barrier
McCalla, A. J., Walker, F. C., Bisaro, F., Rodriguez-Anavitate, M., Johannesman, A., Venanzio, G. D., Feldman, M. F., & LeRoux, M. (2025) · PLoS Pathogens · doi:10.1371/journal.ppat.1013536 · Cited by 11
Applications of different solvents and conditions for differential extraction of lipopolysaccharide in Gram-negative bacteria
Nguyen, M. P., Tran, L. V. H., Namgoong, H., & Kim, Y. (2019) · The Journal of Microbiology · doi:10.1007/s12275-019-9116-5 · Cited by 11
Broad-spectrum suppression of bacterial pneumonia by aminoglycoside-propagated Acinetobacter baumannii
Hood-Pishchany, M. I., Pham, L., Wijers, C. D. M., Burns, W. J., Boyd, K. L., Palmer, L. D., Skaar, E. P., & Noto, M. J. (2020) · PLoS Pathogens · doi:10.1371/journal.ppat.1008374 · Cited by 9
Multidrug-Resistant Acinetobacter baumannii : A Wily, Existential Threat to Modern Healthcare
Maitra, R., Saxena, D., Singh, S., Arya, A. K., Majumder, A., Janani, S., Dasgupta, A., & Chopra, S. (2025) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.5c00570 · Cited by 6
Pathogenicity factors of Acinetobacter baumannii
Gudueva, E. N., & Чемисова, О. С. (2023) · Medical Herald of the South of Russia · doi:10.21886/2219-8075-2023-14-1-66-74 · Cited by 5
Identification of EppR , a Second Repressor of Error‐Prone DNA Polymerase Genes in Acinetobacter baumannii
Nguyen, B. H., Ching, C., MacGuire, A. E., Casula, P., Newman, C., Finley, F., & Godoy, V. G. (2025) · Molecular Microbiology · doi:10.1111/mmi.15368 · Cited by 4
Antibiotic-resistant Acinetobacter baumannii can be killed by a combination of bacteriophages and complement
Chen, C., Krzyżewska, E., Patpatia, S., Dulipati, V., Mapelli, S. N., Meral, A., Kotimaa, J. P., Kiljunen, S., & Meri, S. (2025) · Medical Microbiology and Immunology · doi:10.1007/s00430-025-00852-0 · Cited by 3
A Novel Enterococcus Phage Endolysin Lys22 with a Wide Host Range Against Mixed Biofilm of Enterococcus faecalis, Staphylococcus aureus, and Acinetobacter baumannii
Yang, Z., Du, X. Y., Hu, N., Feng, M.-A., Xu, J., Jiang, H., Zhang, N., Huang, H., Li, J., & Shi, H. (2025) · Pathogens · doi:10.3390/pathogens14101060 · Cited by 3
Acinetobacter Baumannii – Virulence Factors and Epidemiology of Infections
Marszalik, A., Sidor, K., Kraśnicka, A., Wróblewska, M., Skirecki, T., Jagielski, T., & Stachowiak, R. (2021) · Postępy Mikrobiologii - Advancements of Microbiology · doi:10.21307/pm-2021.60.4.21 · Cited by 3
Acinetobacter baumannii: Emergence of a Superbug, Past, Present, and Future
Jalali, Y., Jalali, M., & Payer, J. (2022) · IntechOpen eBooks · doi:10.5772/intechopen.104124 · Cited by 3
Acinetobacter baumannii Virulence Factors and Biofilm Components: Synthesis, Structure, Function, and Inhibitors
Ganesh, P. S., Pathoor, N. N., Muthusamy, R., Sankar, S., Gopal, R. K., & Shankar, E. M. (2024) · Springer eBooks · doi:10.1007/978-981-99-8799-3_10 · Cited by 3
Pangenomics of high-risk international clones in Acinetobacter baumannii identifies distinctive virulence and antimicrobial resistance profiles
Orozco-Ochoa, A. K., Quiñones, B., Lee, B. G., González-Gómez, J. P., Lira-Morales, J. D., Campo, N. C., Valdez-Torres, J. B., & Chaidez-Quíroz, C. (2026) · Archives of Microbiology · doi:10.1007/s00203-026-04738-4 · Cited by 2
Recent Advances in the Immunopathogenesis of Acinetobacter baumannii Infection
de, L., & Che, W. (2012) · InTech eBooks · doi:10.5772/28141 · Cited by 2

Characterization of Acinetobacter baumannii core oligosaccharide synthesis reveals novel aspects of lipooligosaccharide assembly
VanOtterloo, L. M., Macias, L. A., Powers, M. J., Brodbelt, J. S., & Trent, M. S. (2024) · mBio · doi:10.1128/mbio.03013-23 · Cited by 24
Colistin-Resistant, Lipopolysaccharide-Deficient Acinetobacter baumannii Responds to Lipopolysaccharide Loss through Increased Expression of Genes Involved in the Synthesis and Transport of Lipoproteins, Phospholipids, and Poly-β-1,6- N -Acetylglucosamine
Henry, R., Vithanage, N. R., Harrison, P. F., Seemann, T., Coutts, S. A. J., Moffatt, J. H., Nation, R. L., Li, J., Harper, M., Adler, B., et al. (2011) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.05191-11 · Cited by 181
Caracterización de cepas de Acinetobacter baumannii que no producen lipopolisacárido, y su uso en el desarrollo preclínico de anticuerpos preclínico de anticuerpos monoclonales terapéuticos
Ledesma, C., & Claudia, M. S. (2019) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)
Colistin-Resistant, Lipopolysaccharide-Deficient Acinetobacter baumannii Responds to Lipopolysaccharide Loss through Increased Expression of Genes Involved in the Synthesis and Transport of
Harper, M., Adler, D. B., & Boycea, J. D. (2016)
Deletion of a previously uncharacterized lipoprotein lirL confers resistance to an inhibitor of type II signal peptidase in Acinetobacter baumannii
Huang, K.-J., Pantua, H., Diao, J., Skippington, E., Volný, M., Sandoval, W. N., Tiku, V., Peng, Y., Sagolla, M. S., Yan, D., et al. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2123117119 · Cited by 15

Authors: Luke, N. R., Sauberan, S. L., Russo, T. A., Beanan, J. M., Olson, R., Loehfelm, T. W., Cox, A. D., St. Michael, F., Vinogradov, E. V., & Campagnari, A. A.
Affiliations: Department of Microbiology
VA Western New York Healthcare System (US)
University at Buffalo, State University of New York (US)
Institute for Biological Sciences (CA)
Institute for Biological Sciences, National Research Council of Canada, Ottawa, Ontario, Canada K1A 0R6
Corresponding author: Campagnari, Anthony A.
ORCID: Russo, Thomas A.
Loehfelm, Thomas W.
Cox, Andrew D.
Vinogradov, Evgeny V.
Campagnari, Anthony A.
Venue: Infection and Immunity
Publisher: American Society for Microbiology
Published: 2010-05
Volume: 78
Issue: 5
Pages: 2017-2023
ISSN: 0019-9567 (ISSN-L)
1098-5522
DOI: 10.1128/iai.00016-10
PMC: PMC2863528
OpenAlex: W2118531873
Cited by: 114
References: 45
Citations by year: 2026: 5 · 2025: 9 · 2024: 9 · 2023: 8 · 2022: 7 · 2021: 9 · 2020: 6 · 2019: 6 · 2018: 7 · 2017: 5 · 2016: 7 · 2015: 8 · 2014: 7 · 2013: 6 · 2012: 8
FWCI: 3.14
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: journals.asm.org/non-commercial-tdm-license (tdm)
Locations: Infection and Immunity (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
NPARC (submittedVersion)
Funders: National Research Council Canada
Topics: Health Sciences › Medicine › Microbiology (medical) › Antibiotic Resistance in Bacteria
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Bacterial Genetics and Biotechnology
Life Sciences › Immunology and Microbiology › Microbiology › Bacterial Infections and Vaccines
Keywords: Acinetobacter baumannii, LPS core oligosaccharide, 3-deoxy-D-manno-octulosonic acid, lipid A, human serum resistance, bacterial pathogenesis, nosocomial infections
MeSH terms: Acinetobacter Infections, Animals, Bacterial Proteins, Blood Bactericidal Activity, Genetic Complementation Test, Humans, Lipopolysaccharides, Mice, Inbred BALB C, Colony Count, Microbial, Mutagenesis, Insertional, Glycosyltransferases, Conserved Sequence, Sequence Homology, Amino Acid, Soft Tissue Infections, Acinetobacter baumannii, Microbial Viability, Mice, Rats, Gene Knockout Techniques

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Identification and Characterization of a Glycosyltransferase Involved in Acinetobacter baumannii Lipopolysaccharide Core Biosynthesis

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks