The DOI matches its Crossref record; 177 of the 177 references it cites were found in a registry or an index.
Bacterial Virulence in the Moonlight: Multitasking Bacterial Moonlighting Proteins Are Virulence Determinants in Infectious Disease
Open accessAbstract
Men may not be able to multitask, but it is emerging that proteins can. This capacity of proteins to exhibit more than one function is termed protein moonlighting, and, surprisingly, many highly conserved proteins involved in metabolic regulation or the cell stress response have a range of additional biological actions which are involved in bacterial virulence. This review highlights the multiple roles exhibited by a range of bacterial proteins, such as glycolytic and other metabolic enzymes and molecular chaperones, and the role that such moonlighting activity plays in the virulence characteristics of a number of important human pathogens, including Staphylococcus aureus,Streptococcus pyogenes,Streptococcus pneumoniae,Helicobacter pylori, and Mycobacterium tuberculosis.
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Elongation factor Tu is a multifunctional and processed moonlighting protein
Widjaja, M., Harvey, K. L., Hagemann, L., Berry, I. J., Jarocki, V. M., Raymond, B. B. A., Tacchi, J. L., Gründel, A., Steele, J. R., Padula, M. P., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-10644-z · Cited by 131
Coordinating Bacterial Cell Division with Nutrient Availability: a Role for Glycolysis
Monahan, L. G., Hajduk, I. V., Blaber, S. P., Charles, I. G., & Harry, E. J. (2014) · mBio · doi:10.1128/mbio.00935-14 · Cited by 123
Community Interactions of Oral Streptococci
Jakubovics, N. S., Yassin, S. A., & Rickard, A. H. (2014) · Advances in Applied Microbiology · doi:10.1016/b978-0-12-800261-2.00002-5 · Cited by 107
Couto, N., Schooling, S. R., Dutcher, J. R., & Barber, J. (2015) · Journal of Proteome Research · doi:10.1021/acs.jproteome.5b00312 · Cited by 92
Post-translational processing targets functionally diverse proteins in Mycoplasma hyopneumoniae
Tacchi, J. L., Raymond, B. B. A., Haynes, P. A., Berry, I. J., Widjaja, M., Bogema, D. R., Woolley, L. K., Jenkins, C., Minion, F. C., Padula, M. P., et al. (2016) · Open Biology · doi:10.1098/rsob.150210 · Cited by 62
Metadata
- Authors
- Henderson, B., & Martin, A.
- Venue
- Infection and Immunity
- Publisher
- American Society for Microbiology
- Published
- 2011-09
- Volume
- 79
- Issue
- 9
- Pages
- 3476-3491
- ISSN
- 0019-9567 (ISSN-L)
- 1098-5522
- OpenAlex
- W2117414599
- Cited by
- 458
- References
- 177
- FWCI
- 20.83
- Type
- journal article
- Language
- en
- Open access
- green
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- Henderson, B., & Martin, A. (2011). Bacterial Virulence in the Moonlight: Multitasking Bacterial Moonlighting Proteins Are Virulence Determinants in Infectious Disease. Infection and Immunity. https://doi.org/10.1128/iai.00179-11
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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