The DOI matches its Crossref record; 171 of the 171 references it cites were found in a registry or an index.
Lipoproteins of Bacterial Pathogens
Open accessAbstract
Bacterial lipoproteins are a set of membrane proteins with many different functions. Due to this broad-ranging functionality, these proteins have a considerable significance in many phenomena, from cellular physiology through cell division and virulence. Here we give a general overview of lipoprotein biogenesis and highlight examples of the roles of lipoproteins in bacterial disease caused by a selection of medically relevant Gram-negative and Gram-positive pathogens:Mycobacterium tuberculosis,Streptococcus pneumoniae,Borrelia burgdorferi, and Neisseria meningitidis. Lipoproteins have been shown to play key roles in adhesion to host cells, modulation of inflammatory processes, and translocation of virulence factors into host cells. As such, a number of lipoproteins have been shown to be potential vaccines. This review provides a summary of some of the reported roles of lipoproteins and of how this knowledge has been exploited in some cases for the generation of novel countermeasures to bacterial diseases.
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1 retracted
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Cited by
Bacterial Outer Membrane Vesicles: From Discovery to Applications
Sartorio, M. G., Pardue, E. J., Feldman, M. F., & Haurat, M. F. (2021) · Annual Review of Microbiology · doi:10.1146/annurev-micro-052821-031444 · Cited by 398
Bahr, G., González, L. J., & Vila, A. J. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00138 · Cited by 266
Bateman, T. J., Shah, M., Ho, T. P., Shin, H. E., Pan, C., Harris, G., Fegan, J. E., Islam, E. A., Ahn, S. K., Hooda, Y., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-26545-9 · Cited by 44
A lipoprotein partner for the Escherichia coli outer membrane protein TolC
Horne, J., Kaplan, E., Jin, B., Abbott, K., Flores, V., Petsolari, E., Gradon, J., Ntsogo, Y., Harris, A., Yu, D., et al. (2026) · eLife · doi:10.7554/elife.110666.3 · Cited by 3
Legood, S., Oliveira Paiva, A., Taib, N., Ruffiot, T., Gribaldo, S., Gomperts Boneca, I., & Buddelmeijer, N. (2026) · mBio · doi:10.1128/mbio.00600-26 · Cited by 1
Metadata
- Authors
- Kovacs-Simon, A., Titball, R. W., & Michell, S. L.
- Venue
- Infection and Immunity
- Publisher
- American Society for Microbiology
- Published
- 2011-02
- Volume
- 79
- Issue
- 2
- Pages
- 548-561
- ISSN
- 0019-9567 (ISSN-L)
- 1098-5522
- OpenAlex
- W2052308056
- Cited by
- 440
- References
- 171
- FWCI
- 18.01
- Type
- journal article
- Language
- en
- Open access
- green
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