The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
Biological activities of toxins A and B of Clostridium difficile
Open accessAbstract
Examination of the biological activities of the two known toxins of Clostridium difficile revealed that one of the toxins (toxin A) elicited a hemorrhagic fluid response in rabbit intestinal loops and a positive fluid response in infant mice. The other toxin (toxin B) did not produce a significant fluid response in either model, although the toxin was more lethal in infant mice. Both toxins elicited erythematous and hemorrhagic skin reactions and increased vascular permeability in rabbit skin.
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Cites
Antibiotic-associated pseudomembranous colitis due to toxin-producing clostridia
Bartlett, J. G., Chang, T. W., Gurwith, M., Gorbach, S. L., & Onderdonk, A. B. (1978) · New England Journal of Medicine · doi:10.1056/nejm197803092981003 · Cited by 1,374
CLOSTRIDIUM DIFFICILE AND THE ÆTIOLOGY OF PSEUDOMEMBRANOUS COLITIS
Larson, H. E., Price, A. B., Honour, P., & Borriello, S. P. (1978) · The Lancet · doi:10.1016/s0140-6736(78)90912-1 · Cited by 652
Role of Clostridium difficile in antibiotic-associated pseudomembranous colitis
Bartlett, J. G., Moon, N., Chang, T. W., Taylor, N., & Onderdonk, A. B. (1978) · Gastroenterology · doi:10.1016/0016-5085(78)90457-2 · Cited by 517
Clindamycin-Associated Colitis Due to a Toxin-Producing Species of Clostridium in Hamsters
Bartlett, J. G., Onderdonk, A. B., Cisneros, R. L., & Kasper, D. L. (1977) · Journal of Infectious Diseases · doi:10.1093/infdis/136.5.701 · Cited by 472
Identification of Clostridium difficile as a cause of pseudomembranous colitis.
George, R. H., Symonds, J. M., Dimock, F., Brown, J. D., Arabi, Y., Shinagawa, N., Keighley, M. R., Alexander-Williams, J., & Burdon, D. W. (1978) · BMJ · doi:10.1136/bmj.1.6114.695 · Cited by 451
Purification and characterization of toxins A and B of Clostridium difficile
Sullivan, N. M., Pellett, S., & Wilkins, T. D. (1982) · Infection and Immunity · doi:10.1128/iai.35.3.1032-1040.1982 · Cited by 368
Self-citationProduction of Vascular Permeability Factor by Enterotoxigenic Escherichia coli Isolated from Man
Evans, D. J., Evans, D. G., & Gorbach, S. L. (1973) · Infection and Immunity · doi:10.1128/iai.8.5.725-730.1973 · Cited by 188
Clinical and laboratory observations in Clostridium difficile colitis
Bartlett, J. G., Taylor, N. S., Chang, T., & Dzink, J. (1980) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/33.11.2521 · Cited by 162
Clindamycin-Induced Enterocolitis in Hamsters
Lusk, R. H., Fekety, R., Silva, J., Browne, R., Ringler, D. H., & Abrams, G. D. (1978) · The Journal of Infectious Diseases · doi:10.1093/infdis/137.4.464 · Cited by 113
Purification and characterization of Clostridium difficile toxin
Rolfe, R. D., & Finegold, S. M. (1979) · Infection and Immunity · doi:10.1128/iai.25.1.191-201.1979 · Cited by 104
Cited by
Clostridial enteric diseases of domestic animals
Songer, J. G. (1996) · Clinical Microbiology Reviews · doi:10.1128/cmr.9.2.216 · Cited by 909
Enteric bacterial toxins: mechanisms of action and linkage to intestinal secretion
Sears, C. L., & Kaper, J. B. (1996) · Microbiological Reviews · doi:10.1128/mmbr.60.1.167-215.1996 · Cited by 508
Effects of Clostridium difficile toxins given intragastrically to animals
Lyerly, D. M., Saum, K. E., MacDonald, D. K., & Wilkins, T. D. (1985) · Infection and Immunity · doi:10.1128/iai.47.2.349-352.1985 · Cited by 400
Self-citationPurification and characterization of toxins A and B of Clostridium difficile
Sullivan, N. M., Pellett, S., & Wilkins, T. D. (1982) · Infection and Immunity · doi:10.1128/iai.35.3.1032-1040.1982 · Cited by 368
Self-citationThe role of toxins in Clostridium difficile infection
Chandrasekaran, R., & Lacy, D. B. (2017) · FEMS Microbiology Reviews · doi:10.1093/femsre/fux048 · Cited by 353
Metadata
- Authors
- Lyerly, D. M., Lockwood, D. E., Richardson, S. H., & Wilkins, T. D.
- Venue
- Infection and Immunity
- Publisher
- American Society for Microbiology
- Published
- 1982-03
- Volume
- 35
- Issue
- 3
- Pages
- 1147-1150
- ISSN
- 0019-9567 (ISSN-L)
- 1098-5522
- OpenAlex
- W1931706359
- Cited by
- 258
- References
- 16
- FWCI
- 13.62
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Lyerly, D. M., Lockwood, D. E., Richardson, S. H., & Wilkins, T. D. (1982). Biological activities of toxins A and B of Clostridium difficile. Infection and Immunity. https://doi.org/10.1128/iai.35.3.1147-1150.1982
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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