The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Clindamycin-Associated Colitis Due to a Toxin-Producing Species of Clostridium in Hamsters
Abstract
Clindamycin-associated enterocolitis in hamsters was studied to detect and characterize a transmissible agent. It was found that the disease could be transferred by cecal contents and filtrates of cecal contents (pore size of filter, 0.02 micron) obtained from animals after administration of clindamycin. Subsequent work showed that enterocolitis could be produced with broth cultures of a species of Clostridium recovered from cecal contents of animals with clindamycin-induced disease. The cell-free supernatant of this strain also caused enterocolitis. Cecal contents from animals with clindamycin-induced disease incubated with gas gangrene antitoxin failed to cause intestinal lesions. These experiments indicate that clindamycin-associated colitis in hamsters is due to a clindamycin-resistant, toxin-producing strain of Clostridium.
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Citations
Cites
Toxicity of Penicillin for the Syrian Hamster
Schneierson, S. S., & Perlman, E. (1956) · Experimental Biology and Medicine · doi:10.3181/00379727-91-22221 · Cited by 22
Cited by
Antibiotic-associated pseudomembranous colitis due to toxin-producing clostridia
Bartlett, J. G., Chang, T. W., Gurwith, M., Gorbach, S. L., & Onderdonk, A. B. (1978) · New England Journal of Medicine · doi:10.1056/nejm197803092981003 · Cited by 1,374
Self-citationSelective and differential medium for isolation of Clostridium difficile
George, W. L., Sutter, V. L., Citron, D., & Finegold, S. M. (1979) · Journal of Clinical Microbiology · doi:10.1128/jcm.9.2.214-219.1979 · Cited by 632
Antimicrobial‐Associated Risk Factors for Clostridium difficile Infection
Owens, Jr., Donskey, C. J., Gaynes, R. P., Loo, V. G., & Muto, C. A. (2008) · Clinical Infectious Diseases · doi:10.1086/521859 · Cited by 603
Role of Clostridium difficile in antibiotic-associated pseudomembranous colitis
Bartlett, J. G., Moon, N., Chang, T. W., Taylor, N., & Onderdonk, A. B. (1978) · Gastroenterology · doi:10.1016/0016-5085(78)90457-2 · Cited by 517
Self-citationRole of the Intestinal Microbiota in Resistance to Colonization by Clostridium difficile
Britton, R. A., & Young, V. B. (2014) · Gastroenterology · doi:10.1053/j.gastro.2014.01.059 · Cited by 446
Metadata
- Authors
- Bartlett, J. G., Onderdonk, A. B., Cisneros, R. L., & Kasper, D. L.
- Venue
- Journal of Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 1977-11-01
- Volume
- 136
- Issue
- 5
- Pages
- 701-705
- ISSN
- 0022-1899 (ISSN-L)
- 1537-6613
- OpenAlex
- W2049572154
- Cited by
- 472
- References
- 1
- FWCI
- 42.91
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Clindamycin-Associated Colitis Due to a Toxin-Producing Species of Clostridium in Hamsters. https://app.cochat.ai/papers/10.1093/infdis/136.5.701
- The paper
- Bartlett, J. G., Onderdonk, A. B., Cisneros, R. L., & Kasper, D. L. (1977). Clindamycin-Associated Colitis Due to a Toxin-Producing Species of Clostridium in Hamsters. Journal of Infectious Diseases. https://doi.org/10.1093/infdis/136.5.701
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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