The DOI matches its Crossref record.
Pathogenesis of Herpetic Neuritis and Ganglionitis in Mice: Evidence for Intra-Axonal Transport of Infection
Open accessAbstract
The pathogenesis of acute herpetic infection in the nervous system has been studied following rear footpad inoculation of mice. Viral assays performed on appropriate tissues at various time intervals indicated that the infection progressed sequentially from peripheral to the central nervous system, with infectious virus reaching the sacrosciatic spinal ganglia in 20 to 24 hr. The infection also progressed to ganglia in mice given high levels of anti-viral antibody. Immunofluorescent techniques demonstrated that both neurons and supporting cells produced virus-specific antigens. By electron microscopy, neurons were found to produce morphologically complete virions, but supporting cells replicated principally nucleocapsids. These results are discussed in the context of possible mechanisms by which herpes simplex virus might travel in nerve trunks. They are considered to offer strong support for centripetal transport in axons.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Experimental investigation of herpes simplex virus latency
Wagner, E. K., & Bloom, D. C. (1997) · Clinical Microbiology Reviews · doi:10.1128/cmr.10.3.419 · Cited by 284
Gene Delivery Using Herpes Simplex Virus Vectors
Burton, E. A., Fink, D. J., & Glorioso, J. C. (2002) · DNA and Cell Biology · doi:10.1089/104454902762053864 · Cited by 92
Saksena, M. M., Wakisaka, H., Tijono, B., Boadle, R. A., Rixon, F., Takahashi, H., & Cunningham, A. L. (2006) · Journal of Virology · doi:10.1128/jvi.80.7.3592-3606.2006 · Cited by 89
Metadata
- Authors
- Cook, M. L., & Stevens, J. G.
- Venue
- Infection and Immunity
- Publisher
- American Society for Microbiology
- Published
- 1973-02
- Volume
- 7
- Issue
- 2
- Pages
- 272-288
- ISSN
- 0019-9567 (ISSN-L)
- 1098-5522
- OpenAlex
- W2117230571
- Cited by
- 453
- References
- 0
- FWCI
- 18.29
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Pathogenesis of Herpetic Neuritis and Ganglionitis in Mice: Evidence for Intra-Axonal Transport of Infection. https://app.cochat.ai/papers/10.1128/iai.7.2.272-288.1973
- The paper
- Cook, M. L., & Stevens, J. G. (1973). Pathogenesis of Herpetic Neuritis and Ganglionitis in Mice: Evidence for Intra-Axonal Transport of Infection. Infection and Immunity. https://doi.org/10.1128/iai.7.2.272-288.1973
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
