The DOI matches its Crossref record.
The groES and groEL heat shock gene products of Escherichia coli are essential for bacterial growth at all temperatures
Open accessAbstract
The products of the groES and groEL genes of Escherichia coli, constituting the groE operon, are known to be required for growth at high temperature (42 degrees C) and are members of the heat shock regulon. Using a genetic approach, we examined the requirement for these gene products for bacterial growth at low temperature (17 to 30 degrees C). To do this, we constructed various groES groEL heterodiploid derivative strains. By inactivating one of the groE operons by a polar insertion, it was shown by bacteriophage P1 transduction that at least one of the groE genes was essential for growth at low temperature. Further P1 transduction experiments with strains that were heterodiploid for only one of the groE genes demonstrated that both groE gene products were required for growth at low temperature, which suggested a fundamental role for the groE proteins in E. coli growth and physiology.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Proteome-wide Analysis of Chaperonin-Dependent Protein Folding in Escherichia coli
Kerner, M. J., Naylor, D. J., Ishihama, Y., Maier, T., Chang, H.-C., Stines, A. P., Georgopoulos, C., Frishman, D., Hayer-Hartl, M., Mann, M., et al. (2005) · Cell · doi:10.1016/j.cell.2005.05.028 · Cited by 659
Self-citationPolypeptide Flux through Bacterial Hsp70
Teter, S. A., Houry, W. A., Ang, D., Tradler, T., Rockabrand, D., Fischer, G., Blum, P., Georgopoulos, C., & Hartl, F. U. (1999) · Cell · doi:10.1016/s0092-8674(00)80787-4 · Cited by 424
Self-citationHeat Shock Proteins as Ligands of Toll-Like Receptors
Vabulas, R. M., Wagner, H., & Schild, H. (2002) · Current Topics in Microbiology and Immunology · doi:10.1007/978-3-642-59430-4_11 · Cited by 276
Firefly luciferase mutants as sensors of proteome stress
Gupta, R., Kasturi, P., Bracher, A., Loew, C., Zheng, M., Villella, A., Garza, D., Hartl, F. U., & Raychaudhuri, S. (2011) · Nature Methods · doi:10.1038/nmeth.1697 · Cited by 219
Identity and function of a large gene network underlying mutagenic repair of DNA breaks
Al Mamun, A. A. M., Lombardo, M.-J., Shee, C., Lisewski, A. M., Gonzalez, C., Lin, D., Nehring, R. B., Saint-Ruf, C., Gibson, J. L., Frisch, R. L., et al. (2012) · Science · doi:10.1126/science.1226683 · Cited by 224
Metadata
- Authors
- Fayet, O., Ziegelhoffer, T., & Georgopoulos, C.
- Venue
- Journal of Bacteriology
- Publisher
- American Society for Microbiology
- Published
- 1989-03
- Volume
- 171
- Issue
- 3
- Pages
- 1379-1385
- ISSN
- 0021-9193 (ISSN-L)
- 1098-5530
- OpenAlex
- W2138749342
- Cited by
- 705
- References
- 0
- FWCI
- 12.40
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: The groES and groEL heat shock gene products of Escherichia coli are essential for bacterial growth at all temperatures. https://app.cochat.ai/papers/10.1128/jb.171.3.1379-1385.1989
- The paper
- Fayet, O., Ziegelhoffer, T., & Georgopoulos, C. (1989). The groES and groEL heat shock gene products of Escherichia coli are essential for bacterial growth at all temperatures. Journal of Bacteriology. https://doi.org/10.1128/jb.171.3.1379-1385.1989
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
