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Cited by 261

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Influence of the MexAB-OprM Multidrug Efflux System on Quorum Sensing in Pseudomonas aeruginosa

Open access
Evans, Kelly, Passador, Luciano, Srikumar, Ramakrishnan, Tsang, Eric, Nezezon, Jonathon, Poole, Keith·1998·Journal of Bacteriology

Abstract

Pseudomonas aeruginosa nalB mutants which hyperexpress the MexAB-OprM multidrug efflux system produce reduced levels of several extracellular virulence factors known to be regulated by quorum sensing. Such mutants also produce less acylated homoserine lactone autoinducer PAI-1, consistent with an observed reduction in lasI expression. These data suggest that PAI-1 is a substrate for MexAB-OprM, and its resulting exclusion from cells hyperexpressing MexAB-OprM limits PAI-1-dependent activation of lasI and the virulence genes.

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Crossref · 10.1128/jb.180.20.5443-5447.1998

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Metadata

Authors
Evans, K., Passador, L., Srikumar, R., Tsang, E., Nezezon, J., & Poole, K.
Venue
Journal of Bacteriology
Published
1998-10-15
Volume
180
Issue
20
Pages
5443-5447
ISSN
  • 0021-9193 (ISSN-L)
  • 1098-5530
OpenAlex
W1978541321
Cited by
261
References
1
FWCI
3.26
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Influence of the MexAB-OprM Multidrug Efflux System on Quorum Sensing in Pseudomonas aeruginosa. https://app.cochat.ai/papers/10.1128/jb.180.20.5443-5447.1998
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Evans, K., Passador, L., Srikumar, R., Tsang, E., Nezezon, J., & Poole, K. (1998). Influence of the MexAB-OprM Multidrug Efflux System on Quorum Sensing in Pseudomonas aeruginosa. Journal of Bacteriology. https://doi.org/10.1128/jb.180.20.5443-5447.1998

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