The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Isolation and Characterization of the nikR Gene Encoding a Nickel-Responsive Regulator in Escherichia coli
Open accessAbstract
Expression of the nickel-specific transport system encoded by the Escherichia coli nikABCDE operon is repressed by a high concentration of nickel. By using random transposon Tn 10 insertion, we isolated mutants in which expression of the nik operon became constitutive with respect to nickel. We have identified the corresponding nikR gene which encodes a nickel-responsive regulator. Expression of nikR was partially controlled by Fnr through transcription from the nikA promoter region. In addition, a specific transcription start site for the constitutive expression of nikR was found 51 bp upstream of the nikR gene.
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Citations
Cites
de Lorenzo, V, Wee, S., Herrero, M., & Neilands, J. B. (1987) · Journal of Bacteriology · doi:10.1128/jb.169.6.2624-2630.1987 · Cited by 536 · cited 1×
“The potential NikR-binding site contains two half sites of 14 bp separated by 10 bp (see above), whereas the perfect dyad of the Fur box is separated by one nucleotide (3).”
Background
Cited by
Coordination Chemistry of Bacterial Metal Transport and Sensing
Ma, Z., Jacobsen, F. E., & Giedroc, D. P. (2009) · Chemical Reviews · doi:10.1021/cr900077w · Cited by 621
Nickel uptake and utilization by microorganisms
Mulrooney, S. B., & Hausinger, R. P. (2003) · FEMS Microbiology Reviews · doi:10.1016/s0168-6445(03)00042-1 · Cited by 516
Dudev, T., & Lim, C. (2014) · Chemical Reviews · doi:10.1021/cr4004665 · Cited by 451
Mechanisms of nickel toxicity in microorganisms
Macomber, L., & Hausinger, R. P. (2011) · Metallomics · doi:10.1039/c1mt00063b · Cited by 358
Rodionov, D. A., Hebbeln, P., Gelfand, M. S., & Eitinger, T. (2006) · Journal of Bacteriology · doi:10.1128/jb.188.1.317-327.2006 · Cited by 295
Metadata
- Authors
- De Pina, K., Desjardin, V., Mandrand-Berthelot, M.-A., Giordano, G., & Wu, L.-F.
- Venue
- Journal of Bacteriology
- Publisher
- American Society for Microbiology
- Published
- 1999-01-15
- Volume
- 181
- Issue
- 2
- Pages
- 670-674
- ISSN
- 0021-9193 (ISSN-L)
- 1098-5530
- OpenAlex
- W1563527550
- Cited by
- 178
- References
- 1
- FWCI
- 2.87
- Type
- journal article
- Language
- en
- Open access
- green
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- The paper
- De Pina, K., Desjardin, V., Mandrand-Berthelot, M.-A., Giordano, G., & Wu, L.-F. (1999). Isolation and Characterization of the nikR Gene Encoding a Nickel-Responsive Regulator in Escherichia coli. Journal of Bacteriology. https://doi.org/10.1128/jb.181.2.670-674.1999
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
