Cited by 112Antimicrobial Resistance in StaphylococcusStreptococcal Infections and TreatmentsOrthopedic Infections and Treatments

The DOI matches its Crossref record; 70 of the 70 references it cites were found in a registry or an index.

Comparative Genomics of Staphylococcus aureus Musculoskeletal Isolates

Open access

Cassat, James E., Dunman, Paul M., McAleese, Fionnuala, Murphy, Ellen, Projan, Steven J., Smeltzer, Mark S.·2005·Journal of Bacteriology

DOI 10.1128/jb.187.2.576-592.2005PMC PMC543526

Open this paper in CoChat — free account

Abstract

Much of the research aimed at defining the pathogenesis of Staphylococcus aureus has been done with a limited number of strains, most notably the 8325-4 derivative RN6390. Several lines of evidence indicate that this strain is unique by comparison to clinical isolates of S. aureus. Based on this, we have focused our efforts on two clinical isolates (UAMS-1 and UAMS-601), both of which are hypervirulent in our animal models of musculoskeletal infection. In this study, we used comparative genomic hybridization to assess the genome content of these two isolates relative to RN6390 and each of seven sequenced S. aureus isolates. Our comparisons were done by using an amplicon-based microarray from the Pathogen Functional Genomics Resource Center and an Affymetrix GeneChip that collectively represent the genomes of all seven sequenced strains. Our results confirmed that UAMS-1 and UAMS-601 share specific attributes that distinguish them from RN6390. Potentially important differences included the presence of cna and the absence of isaB, sarT, sarU, and sasG in the UAMS isolates. Among the sequenced strains, the UAMS isolates were most closely related to the dominant European clone EMRSA-16. In contrast, RN6390, NCTC 8325, and COL formed a distinct cluster that, by comparison to the other four sequenced strains (Mu50, N315, MW2, and SANGER-476), was the most distantly related to the UAMS isolates and EMRSA-16.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1128/jb.187.2.576-592.2005

Cites

70 of 70 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Multilocus sequence typing: A portable approach to the identification of clones within populations of pathogenic microorganisms
Maiden, M. C. J., Bygraves, J. A., Feil, E. J., Morelli, G., Russell, J. E., Urwin, R., Zhang, Q., Zhou, J., Zurth, K., Caugant, D. A., et al. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.6.3140 · Cited by 3,891
Multilocus Sequence Typing for Characterization of Methicillin-Resistant and Methicillin-Susceptible Clones ofStaphylococcus aureus
Enright, M. C., Day, N., Davies, C. E., Peacock, S. J., & Spratt, B. G. (2000) · Journal of Clinical Microbiology · doi:10.1128/jcm.38.3.1008-1015.2000 · Cited by 3,039
Involvement of Panton-Valentine Leukocidin--Producing Staphylococcus aureus in Primary Skin Infections and Pneumonia
Lina, G., Piemont, Y., Godail-Gamot, F., Bes, M., Peter, M.-O., Gauduchon, V., Vandenesch, F., & Etienne, J. (1999) · Clinical Infectious Diseases · doi:10.1086/313461 · Cited by 2,489
Whole genome sequencing of meticillin-resistant Staphylococcus aureus
Kuroda, M., Ohta, T., Uchiyama, I., Baba, T., Yuzawa, H., Kobayashi, I., Cui, L., Oguchi, A., Aoki, K.-I., Nagai, Y., et al. (2001) · The Lancet · doi:10.1016/s0140-6736(00)04403-2 · Cited by 1,950
The evolutionary history of methicillin-resistant Staphylococcus aureus (MRSA)
Enright, M. C., Robinson, D. A., Randle, G. A., Feil, E. J., Grundmann, H., & Spratt, B. G. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.122108599 · Cited by 1,591
Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients
Gillet, Y., Issartel, B., Vanhems, P., Fournet, J.-C., Lina, G., Bes, M., Vandenesch, F., Piémont, Y., Brousse, N., Floret, D., et al. (2002) · The Lancet · doi:10.1016/s0140-6736(02)07877-7 · Cited by 1,514
Genome and virulence determinants of high virulence community-acquired MRSA
Baba, T., Takeuchi, F., Kuroda, M., Yuzawa, H., Aoki, K.-I., Oguchi, A., Nagai, Y., Iwama, N., Asano, K., Naimi, T. S., et al. (2002) · The Lancet · doi:10.1016/s0140-6736(02)08713-5 · Cited by 1,356
Multiplex PCR Strategy for Rapid Identification of Structural Types and Variants of the mec Element in Methicillin-Resistant Staphylococcus aureus
Oliveira, D. C., & de LENCASTRE, H. (2002) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.46.7.2155-2161.2002 · Cited by 1,344
Autoinduction and signal transduction in the regulation of staphylococcal virulence
Novick, R. P. (2003) · Molecular Microbiology · doi:10.1046/j.1365-2958.2003.03526.x · Cited by 1,271
Relationships between Staphylococcus aureus Genetic Background, Virulence Factors, agr Groups (Alleles), and Human Disease
Jarraud, S., Mougel, C., Thioulouse, J., Lina, G., Meugnier, H., Forey, F., Nesme, X., Étienne, J., & Vandenesch, F. (2002) · Infection and Immunity · doi:10.1128/iai.70.2.631-641.2002 · Cited by 1,147

Show all 70 references

Sorted by citations

Reemergence of antibiotic-resistant Staphylococcus aureus in the genomics era
DeLeo, F. R., & Chambers, H. F. “. (2009) · Journal of Clinical Investigation · doi:10.1172/jci38226 · Cited by 522
Modulation of eDNA Release and Degradation Affects Staphylococcus aureus Biofilm Maturation
Mann, E. E., Rice, K. C., Boles, B. R., Endres, J. L., Ranjit, D. K., Chandramohan, L., Tsang, L. H., Smeltzer, M. S., Horswill, A. R., & Bayles, K. W. (2009) · PLoS ONE · doi:10.1371/journal.pone.0005822 · Cited by 508
Polysaccharide intercellular adhesin or protein factors in biofilm accumulation of Staphylococcus epidermidis and Staphylococcus aureus isolated from prosthetic hip and knee joint infections
Rohde, H., Burandt, E., Siemssen, N., Frommelt, L., Burdelski, C. M., Wurster, S., Scherpe, S., Davies, A. P., Harris, L. G., Horstkotte, M. A., et al. (2006) · Biomaterials · doi:10.1016/j.biomaterials.2006.11.046 · Cited by 489
A comparative genomic view of clostridial sporulation and physiology
Paredes, C. J., Alsaker, K. V., & Papoutsakis, E. T. (2005) · Nature Reviews Microbiology · doi:10.1038/nrmicro1288 · Cited by 343
Role of the Accessory Gene Regulator agr in Community-Associated Methicillin-Resistant Staphylococcus aureus Pathogenesis
Cheung, G. Y. C., Wang, R., Khan, B. A., Sturdevant, D. E., & Otto, M. J. (2011) · Infection and Immunity · doi:10.1128/iai.00046-11 · Cited by 332
Characterization of the Staphylococcus aureus Heat Shock, Cold Shock, Stringent, and SOS Responses and Their Effects on Log-Phase mRNA Turnover
Anderson, K. L., Roberts, C., Disz, T. L., Vonstein, V., Hwang, K., Overbeek, R., Olson, P. D., Projan, S. J., & Dunman, P. M. (2006) · Journal of Bacteriology · doi:10.1128/jb.00609-06 · Cited by 271
Interaction of staphylococci with bone
Wright, J. A., & Nair, S. P. (2009) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2009.10.003 · Cited by 268
Direct Targets of CodY in Staphylococcus aureus
Majerczyk, C. D., Dunman, P. M., Luong, T. T., Lee, C. Y., Sadykov, M. R., Somerville, G. A., Bodi, K. L., & Sonenshein, A. L. (2010) · Journal of Bacteriology · doi:10.1128/jb.00220-10 · Cited by 221
Epistatic Relationships between sarA and agr in Staphylococcus aureus Biofilm Formation
Beenken, K. E., Mrak, L. N., Griffin, L. M., Zielinska, A. K., Shaw, L. N., Rice, K. C., Horswill, A. R., Bayles, K. W., & Smeltzer, M. S. (2010) · PLoS ONE · doi:10.1371/journal.pone.0010790 · Cited by 193
Immunization with Staphylococcus aureus Clumping Factor B, a Major Determinant in Nasal Carriage, Reduces Nasal Colonization in a Murine Model
Schaffer, A. C., Solinga, R. M., Cocchiaro, J. L., Portolés, M., Kiser, K. B., Risley, A., Randall, S. M., Valtulina, V., Speziale, P., Walsh, E. J., et al. (2006) · Infection and Immunity · doi:10.1128/iai.74.4.2145-2153.2006 · Cited by 174
Entropically driven aggregation of bacteria by host polymers promotes antibiotic tolerance in Pseudomonas aeruginosa
Secor, P. R., Michaels, L. A., Ratjen, A., Jennings, L. K., & Singh, P. K. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1806005115 · Cited by 163
Influenza virus primes mice for pneumonia from Staphylococcus aureus.
Iverson, A. R., Boyd, K. L., McAuley, J. L., Plano, L. R., Hart, M. E., & McCullers, J. A. (2011) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiq113 · Cited by 168
Synergistic Photothermal and Antibiotic Killing of Biofilm-Associated Staphylococcus aureus Using Targeted Antibiotic-Loaded Gold Nanoconstructs
Meeker, D. G., Jenkins, S. V., Miller, E. K., Beenken, K. E., Loughran, A. J., Powless, A. J., Muldoon, T. J., Galanzha, E. I., Zharov, V. P., Smeltzer, M. S., et al. (2016) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.5b00117 · Cited by 163
Transcriptional profiling of a Staphylococcus aureus clinical isolate and its isogenic agr and sarA mutants reveals global differences in comparison to the laboratory strain RN6390
Cassat, J. E., Dunman, P. M., Murphy, E., Projan, S. J., Beenken, K. E., Palm, K. J., Yang, S., Rice, K. C., Bayles, K. W., & Smeltzer, M. S. (2006) · Microbiology · doi:10.1099/mic.0.29033-0 · Cited by 154
Murine Immune Response to a Chronic Staphylococcus aureus Biofilm Infection
Prabhakara, R., Harro, J. M., Leid, J. G., Harris, M. L., & Shirtliff, M. E. (2011) · Infection and Immunity · doi:10.1128/iai.01386-10 · Cited by 126
Factors Contributing to the Biofilm-Deficient Phenotype of Staphylococcus aureus sarA Mutants
Tsang, L. H., Cassat, J. E., Shaw, L. N., Beenken, K. E., & Smeltzer, M. S. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003361 · Cited by 126
Characterizing the Effect of theStaphylococcus aureusVirulence Factor Regulator, SarA, on Log-Phase mRNA Half-Lives
Roberts, C., Anderson, K. L., Murphy, E., Projan, S. J., Mounts, W. M., Hurlburt, B. K., Smeltzer, M. S., Overbeek, R., Disz, T. L., & Dunman, P. M. (2006) · Journal of Bacteriology · doi:10.1128/jb.188.7.2593-2603.2006 · Cited by 118
An Essential Role for Coagulase inStaphylococcus aureusBiofilm Development Reveals New Therapeutic Possibilities for Device-Related Infections
Zapotoczna, M., McCarthy, H., Rudkin, J., O’Gara, J. P., & O’Neill, E. (2015) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiv319 · Cited by 117
The agr Radiation: an Early Event in the Evolution of Staphylococci
Wright, J. S., Traber, K. E., Corrigan, R. M., Benson, S. A., Musser, J. M., & Novick, R. P. (2005) · Journal of Bacteriology · doi:10.1128/jb.187.16.5585-5594.2005 · Cited by 114
Changes in the Staphylococcus aureus Transcriptome during Early Adaptation to the Lung
Chaffin, D. O., Taylor, D., Skerrett, S. J., & Rubens, C. E. (2012) · PLoS ONE · doi:10.1371/journal.pone.0041329 · Cited by 97
Comparative Genomics of Canadian Epidemic Lineages of Methicillin-Resistant Staphylococcus aureus
Christianson, S., Golding, G. R., Campbell, J., & Mulvey, M. R. (2007) · Journal of Clinical Microbiology · doi:10.1128/jcm.02500-06 · Cited by 96
Impact of individual extracellular proteases on Staphylococcus aureus biofilm formation in diverse clinical isolates and their isogenic sarA mutants
Loughran, A. J., Atwood, D. N., Anthony, A. C., Harik, N., Spencer, H. J., Beenken, K. E., & Smeltzer, M. S. (2014) · MicrobiologyOpen · doi:10.1002/mbo3.214 · Cited by 95
CodY-Mediated Regulation of the Staphylococcus aureus Agr System Integrates Nutritional and Population Density Signals
Roux, A., Todd, D. A., Velázquez, J. V., Cech, N. B., & Sonenshein, A. L. (2014) · Journal of Bacteriology · doi:10.1128/jb.00128-13 · Cited by 94
saeRS and sarA Act Synergistically to Repress Protease Production and Promote Biofilm Formation in Staphylococcus aureus
Mrak, L. N., Zielinska, A. K., Beenken, K. E., Mrak, I. N., Atwood, D. N., Griffin, L. M., Lee, C. Y., & Smeltzer, M. S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0038453 · Cited by 93
Defining the Strain-Dependent Impact of the Staphylococcal Accessory Regulator ( sarA ) on the Alpha-Toxin Phenotype of Staphylococcus aureus
Zielinska, A. K., Beenken, K. E., Joo, H., Mrak, L. N., Griffin, L. M., Luong, T. T., Lee, C. Y., Otto, M. J., Shaw, L. N., & Smeltzer, M. S. (2011) · Journal of Bacteriology · doi:10.1128/jb.01517-10 · Cited by 88
Role ofmgrAandsarAin Methicillin‐ResistantStaphylococcus aureusAutolysis and Resistance to Cell Wall–Active Antibiotics
Trotonda, M. P., Xiong, Y.-Q., Memmi, G., Bayer, A. S., & Cheung, A. L. (2008) · The Journal of Infectious Diseases · doi:10.1086/595740 · Cited by 79
DNA microarray technology: a new tool for the epidemiological typing of bacterial pathogens?
Garaizar, J., Rementerı́a, A., & Porwollik, S. (2006) · FEMS Immunology & Medical Microbiology · doi:10.1111/j.1574-695x.2006.00081.x · Cited by 80
The staphylococcal accessory regulator, SarA, is an RNA-binding protein that modulates the mRNA turnover properties of late-exponential and stationary phase Staphylococcus aureus cells
Morrison, J. M. (2012) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2012.00026 · Cited by 72
Pathogen comparative genomics in the next-generation sequencing era: genome alignments, pangenomics and metagenomics
Hu, B., Xie, G. G., Lo, C., Starkenburg, S. R., & Chain, P. (2011) · Briefings in Functional Genomics · doi:10.1093/bfgp/elr042 · Cited by 74
Relative Quantitative Comparisons of the Extracellular Protein Profiles ofStaphylococcus aureusUAMS-1 and ItssarA,agr, andsarA agrRegulatory Mutants Using One-Dimensional Polyacrylamide Gel Electrophoresis and Nanocapillary Liquid Chromatography Coupled with Tandem Mass Spectrometry
Jones, R. C., Deck, J., Edmondson, R. D., & Hart, M. E. (2008) · Journal of Bacteriology · doi:10.1128/jb.00383-08 · Cited by 72
Phenotypic and genotypic characterisation of Staphylococcus aureus causing musculoskeletal infections
Post, V., Wahl, P. M., Uçkay, İ., Ochsner, P. E., Zimmerli, W., Corvec, S., Loïez, C., Richards, R. G., & Moriarty, T. F. (2014) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2014.03.003 · Cited by 69
Production of the Bsa Lantibiotic by Community-Acquired Staphylococcus aureus Strains
Daly, K. M., Upton, M., Sandiford, S. K., Draper, L. A., Wescombe, P. A., Jack, R. W., O’Connor, P. M., Rossney, A. S., Götz, F., Hill, C., et al. (2009) · Journal of Bacteriology · doi:10.1128/jb.01375-09 · Cited by 70
Penicillin Binding Protein 1 Is Important in the Compensatory Response of Staphylococcus aureus to Daptomycin-Induced Membrane Damage and Is a Potential Target for β-Lactam–Daptomycin Synergy
Berti, A. D., Theisen, E., Sauer, J., Nonejuie, P., Olson, J., Pogliano, J., Sakoulas, G., Nizet, V., Proctor, R. A., & Rose, W. E. (2015) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02071-15 · Cited by 67
Characterizing the effects of inorganic acid and alkaline shock on theStaphylococcus aureustranscriptome and messenger RNA turnover
Anderson, K. L., Roux, C. M., Olson, M. W., Luong, T. T., Lee, C. Y., Olson, R., & Dunman, P. M. (2010) · FEMS Immunology & Medical Microbiology · doi:10.1111/j.1574-695x.2010.00736.x · Cited by 62
Staphylococcus aureus Fibronectin Binding Protein A Mediates Biofilm Development and Infection
Gries, C. M., Biddle, T. A., Bose, J. L., Kielian, T., & Lo, D. D. (2020) · Infection and Immunity · doi:10.1128/iai.00859-19 · Cited by 62
The Chemical and Antibacterial Evaluation of St. John's Wort Oil Macerates Used in Kosovar Traditional Medicine
Lyles, J. T., Kim, A., Nelson, K., Bullard-Roberts, A. L., Hajdari, A., Mustafa, B., & Quave, C. L. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.01639 · Cited by 60
Comparative phylogenomics of pathogenic bacteria by microarray analysis
Dorrell, N., Hinchliffe, S. J., & Wren, B. W. (2005) · Current Opinion in Microbiology · doi:10.1016/j.mib.2005.08.012 · Cited by 60
Current status and future prospects for a vaccine against American trypanosomiasis
Garg, N. J., & Bhatia, V. (2005) · Expert Review of Vaccines · doi:10.1586/14760584.4.6.867 · Cited by 59
Impact of sarA and Phenol-Soluble Modulins on the Pathogenesis of Osteomyelitis in Diverse Clinical Isolates of Staphylococcus aureus
Loughran, A. J., Gaddy, D., Beenken, K. E., Meeker, D. G., Morello, R., Zhao, H., Byrum, S. D., Tackett, A. J., Cassat, J. E., & Smeltzer, M. S. (2016) · Infection and Immunity · doi:10.1128/iai.00152-16 · Cited by 57
When will the genomics investment pay off for antibacterial discovery?
Mills, S. D. (2006) · Biochemical Pharmacology · doi:10.1016/j.bcp.2005.11.025 · Cited by 58
Large-scale genetic variation of the symbiosis-required megaplasmid pSymA revealed by comparative genomic analysis of Sinorhizobium meliloti natural strains
Giuntini, E., Mengoni, A., Filippo, C. D., Cavalieri, D., Aubin‐Horth, N., Landry, C. R., Becker, A., & Bazzicalupo, M. (2005) · BMC Genomics · doi:10.1186/1471-2164-6-158 · Cited by 57
Identification and characterization of msa (SA1233), a gene involved in expression of SarA and several virulence factors in Staphylococcus aureus
Sambanthamoorthy, K., Smeltzer, M. S., & Elasri, M. O. (2006) · Microbiology · doi:10.1099/mic.0.29071-0 · Cited by 53
Expression of the sarA family of genes in different strains of Staphylococcus aureus
Ballal, A. D., & Manna, A. C. (2009) · Microbiology · doi:10.1099/mic.0.027417-0 · Cited by 48
Clonal Structure and Characterization of Staphylococcus aureus Strains from Invasive Infections in Paediatric Patients from South Poland: Association between Age, spa Types, Clonal Complexes, and Genetic Markers
Ilczyszyn, W. M., Sabat, A. J., Akkerboom, V., Szkarłat, A., Klepacka, J., Sowa-Sierant, I., Wasik, B., Kosecka-Strojek, M., Buda, A., Międzobrodzki, J., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0151937 · Cited by 47
Pathogenesis of staphylococcal device-related infections: from basic science to new diagnostic, therapeutic and prophylactic approaches
Rohde, H., Mack, D., Christner, M., Burdelski, C. M., Franke, G. C., & Knobloch, J. K. ‐. (2006) · Reviews in Medical Microbiology · doi:10.1097/01.revmedmi.0000244134.43170.83 · Cited by 46
Characterization of SSR42, a Novel Virulence Factor Regulatory RNA That Contributes to the Pathogenesis of a Staphylococcus aureus USA300 Representative
Morrison, J. M., Miller, E. W., Benson, M. A., Alonzo, F., Yoong, P., Torres, V. J., Hinrichs, S. H., & Dunman, P. M. (2012) · Journal of Bacteriology · doi:10.1128/jb.06708-11 · Cited by 50
Comparative genomics of vesicomyid clam (Bivalvia: Mollusca) chemosynthetic symbionts
Newton, I. L. G., Girguis, P. R., & Cavanaugh, C. M. (2008) · BMC Genomics · doi:10.1186/1471-2164-9-585 · Cited by 48
Staphylococcus aureus surface protein SasG contributes to intercellular autoaggregation of Staphylococcus aureus
Kuroda, M., Ito, R., Tanaka, Y., Yao, M., Matoba, K., Saito, S., Tanaka, I., & Ohta, T. (2008) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2008.10.134 · Cited by 41
Proteomics of Staphylococcus aureus biofilm matrix in a rat model of orthopedic implant-associated infection
Lei, M. G., Gupta, R. K., & Lee, C. Y. (2017) · PLoS ONE · doi:10.1371/journal.pone.0187981 · Cited by 39
Pathology and Biofilm Formation in a Porcine Model of Staphylococcal Osteomyelitis
Johansen, L. K., Koch, J., Frees, D., Aalbæk, B., Nielsen, O. L., Leifsson, P. S., Iburg, T. M., Svalastoga, E., Buelund, L. E., Bjarnsholt, T., et al. (2012) · Journal of Comparative Pathology · doi:10.1016/j.jcpa.2012.01.018 · Cited by 39
Examination of the S taphylococcus aureus nitric oxide reductase (sa NOR ) reveals its contribution to modulating intracellular NO levels and cellular respiration
Lewis, A. M., Matzdorf, S. S., Endres, J. L., Windham, I. H., Bayles, K. W., & Rice, K. C. (2015) · Molecular Microbiology · doi:10.1111/mmi.12962 · Cited by 37
Phenotypic and genotypic characterization of Staphylococci causing breast peri-implant infections in oncologic patients
Barbieri, R., Pesce, M., Franchelli, S., Baldelli, I., Maria, A. D., & Marchese, A. E. (2015) · BMC Microbiology · doi:10.1186/s12866-015-0368-x · Cited by 35
Staphylococcus aureus immunodominant surface antigen B is a cell-surface associated nucleic acid binding protein
Mackey-Lawrence, N. M., Potter, D. E., Cerca, N., & Jefferson, K. K. (2009) · BMC Microbiology · doi:10.1186/1471-2180-9-61 · Cited by 35
In Vitro and In Vivo Synergy of the Oxadiazole Class of Antibacterials with β-Lactams
Janardhanan, J., Meisel, J. E., Ding, D., Schroeder, V. A., Wolter, W. R., Mobashery, S., & Chang, M. (2016) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00787-16 · Cited by 35
Molecular Basis of Pathogenicity
Smeltzer, M. S., Lee, C. Y., Harik, N., & Hart, M. E. (2009) · Wiley eBooks · doi:10.1002/9781444308464.ch4 · Cited by 37
Mutation of traP in Staphylococcus aureus Has No Impact on Expression of agr or Biofilm Formation
Tsang, L. H., Daily, S. T., Weiss, E. C., & Smeltzer, M. S. (2007) · Infection and Immunity · doi:10.1128/iai.00603-07 · Cited by 34
Genetic diversity of emerging Panton–Valentine leukocidine/arginine catabolic mobile element (ACME)-positive ST8 SCCmec-IVa meticillin-resistant Staphylococcus aureus (MRSA) strains and ACME-positive CC5 (ST5/ST764) MRSA strains in northern Japan
Kawaguchiya, M., Urushibara, N., Ghosh, S., Kuwahara, O., Morimoto, S., Ito, M., Kudo, K., & Kobayashi, N. (2013) · Journal of Medical Microbiology · doi:10.1099/jmm.0.062125-0 · Cited by 33
Clinical and molecular epidemiology of invasive Staphylococcus aureus infection in Utah children; continued dominance of MSSA over MRSA
Crandall, H., Kapusta, A., Killpack, J., Heyrend, C., Nilsson, K., Dickey, M., Daly, J. A., Ampofo, K., Pavia, A. T., Mulvey, M. A., et al. (2020) · PLoS ONE · doi:10.1371/journal.pone.0238991 · Cited by 33
Development of an in vitro colonization model to investigateStaphylococcus aureusinteractions with airway epithelia
Kiedrowski, M. R., Paharik, A. E., Ackermann, L. W., Shelton, A. U., Singh, S. B., Starner, T. D., & Horswill, A. R. (2015) · Cellular Microbiology · doi:10.1111/cmi.12543 · Cited by 31
Staphylococcus aureus Rbf Activates Biofilm Formation In Vitro and Promotes Virulence in a Murine Foreign Body Infection Model
Luong, T. T., Lei, M. G., & Lee, C. Y. (2008) · Infection and Immunity · doi:10.1128/iai.00872-08 · Cited by 31
Proteomic Analysis of Cell Envelope fromStaphylococcusxylosusC2a, a Coagulase-Negative Staphylococcus
Planchon, S., Chambon, C., Desvaux, M., Chafsey, I., Léroy, S., Talòn, R., & Hébraud, M. (2007) · Journal of Proteome Research · doi:10.1021/pr070139+ · Cited by 27
Transcribing virulence inStaphylococcus aureus
Junecko, J. M. (2012) · World Journal of Clinical Infectious Diseases · doi:10.5495/wjcid.v2.i4.63 · Cited by 27
Genome Sequence of the Clinical Isolate Staphylococcus aureus subsp. aureus Strain UAMS-1
Sassi, M., Sharma, D., Brinsmade, S. R., Felden, B., & Augagneur, Y. (2015) · Genome Announcements · doi:10.1128/genomea.01584-14 · Cited by 25
Antibodies to Staphylococcus aureus Bone Sialoprotein-Binding Protein Indicate Infectious Osteomyelitis
Persson, L., Johansson, C., & Rydèn, C. (2009) · Clinical and Vaccine Immunology · doi:10.1128/cvi.00442-08 · Cited by 22
Staphylococcus aureus Biofilm-Associated Infections: Have We Found a Clinically Relevant Target?
Beenken, K. E., & Smeltzer, M. S. (2025) · Microorganisms · doi:10.3390/microorganisms13040852 · Cited by 21
Antibodies toStaphylococcus aureuscapsular polysaccharides 5 and 8 perform similarlyin vitrobut are functionally distinctin vivo
Liu, B., Park, S., Thompson, C. D., Li, X., & Lee, J. C. (2016) · Virulence · doi:10.1080/21505594.2016.1270494 · Cited by 21
The major role of sarA in limiting Staphylococcus aureus extracellular protease production in vitro is correlated with decreased virulence in diverse clinical isolates in osteomyelitis
Campbell, M. J., Beenken, K. E., Ramírez, A. M., & Smeltzer, M. S. (2023) · Virulence · doi:10.1080/21505594.2023.2175496 · Cited by 21
Epidemiology of transmissible diseases: Array hybridization and next generation sequencing as universal nucleic acid-mediated typing tools
Dunne, W. M., Pouseele, H., Monecke, S., Ehricht, R., & van Belkum, A. (2017) · Infection Genetics and Evolution · doi:10.1016/j.meegid.2017.09.019 · Cited by 21
Detection and Genetic Characterization of PVL-Positive ST8-MRSA-IVa and Exfoliative Toxin D-Positive European CA-MRSA-Like ST1931 (CC80) MRSA-IVa Strains in Bangladesh
Paul, S. K., Ghosh, S., Kawaguchiya, M., Urushibara, N., Hossain, M. A., Ahmed, S., Mahmud, C., Jilani, M. S. A., Haq, J. A., Ahmed, A. A., et al. (2014) · Microbial Drug Resistance · doi:10.1089/mdr.2013.0153 · Cited by 20
Hyaluronidase expression and biofilm involvement in Staphylococcus aureus UAMS-1 and its sarA, agr and sarA agr regulatory mutants
Hart, M. E., Tsang, L. H., Deck, J., Daily, S. T., Jones, R. C., Liu, H., Hu, H., Hart, M. J., & Smeltzer, M. S. (2013) · Microbiology · doi:10.1099/mic.0.065367-0 · Cited by 20
Improving the Treatment of Musculoskeletal Infections with Molecular Diagnostics
Tarkin, I. S., Dunman, P. M., & Garvin, K. L. (2005) · Clinical Orthopaedics and Related Research · doi:10.1097/01.blo.0000175126.37343.44 · Cited by 20
Cinnamonitrile Adjuvants Restore Susceptibility to β-Lactams against Methicillin-Resistant Staphylococcus aureus
Speri, E., Kim, C. K., Benedetti, S. D., Qian, Y., Lastochkin, E., Fishovitz, J., Fisher, J. F., & Mobashery, S. (2019) · ACS Medicinal Chemistry Letters · doi:10.1021/acsmedchemlett.9b00169 · Cited by 19
Regulatory Mutations Impacting Antibiotic Susceptibility in an Established Staphylococcus aureus Biofilm
Atwood, D. N., Beenken, K. E., Lantz, T. L., Meeker, D. G., Lynn, W. B., Mills, W. B., Spencer, H. J., & Smeltzer, M. S. (2016) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02750-15 · Cited by 18
Genome-scale transcriptional profiling inStaphylococcus aureus : bringing order out of chaos
Nagarajan, V., Smeltzer, M. S., & Elasri, M. O. (2009) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2009.01595.x · Cited by 18
Limiting protease production plays a key role in the pathogenesis of the divergent clinical isolates of Staphylococcus aureus LAC and UAMS-1
Rom, J. S., Beenken, K. E., Ramírez, A. M., Walker, C. M., Echols, E. J., & Smeltzer, M. S. (2021) · Virulence · doi:10.1080/21505594.2021.1879550 · Cited by 15
Increased production of aureolysin and staphopain A is a primary determinant of the reduced virulence of Staphylococcus aureus sarA mutants in osteomyelitis
Campbell, M. J., Beenken, K. E., Ramírez, A. M., & Smeltzer, M. S. (2024) · mBio · doi:10.1128/mbio.03383-23 · Cited by 14
Use of genome information for the study of the pathogenesis of fungal infections and the development of diagnostic tools
Saville, S. P., Thomas, D. P., & Lopez-Ribot, J. L. (2005) · Revista Iberoamericana de Micología · doi:10.1016/s1130-1406(05)70049-8 · Cited by 14
Staphylococcus aureus Efflux Pumps and Tolerance to Ciprofloxacin and Chlorhexidine following Induction by Mupirocin
Truong, Q. C., Wang, Y., Reedy, J. L., Vyas, J. M., & Hooper, D. C. (2021) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01845-21 · Cited by 13
Tryptoline-based benzothiazoles re-sensitize MRSA to β-lactam antibiotics
Wang, X., Chen, J., Wang, W., Jaunarajs, A., & Wang, X. (2019) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2019.115095 · Cited by 12
Staphylococcus aureus surface protein G (sasG) allelic variants: correlation between biofilm formation and their prevalence in methicillin-resistant S. aureus (MRSA) clones
Carrera-Salinas, A., González-Díaz, A., Vázquez-Sánchez, D. A., Camoez, M., Niubó, J., Cámara, J., Ardanuy, C., Martí, S., Domínguez, M. Á., García, M., et al. (2022) · Research in Microbiology · doi:10.1016/j.resmic.2022.103921 · Cited by 12
Epidemiology and Virulence Insights from MRSA and MSSA Genome Analysis
Lazarević, V., Beaume, M. G., Corvaglia, A., Hernández, D., Schrenzel, J., & François, P. (2011) · Future Microbiology · doi:10.2217/fmb.11.38 · Cited by 11
Phenotypic Variation Is Almost Entirely Independent of the Host-Pathogen Relationship in Clinical Isolates of S. aureus
Land, A. D., Hogan, P. G., Fritz, S. A., & Levin, P. A. (2015) · PLoS ONE · doi:10.1371/journal.pone.0129670 · Cited by 9
Persistence of bacterial DNA in orthopedic infections
Kaplan, H. B., Miranda, J. A., Gogola, G. R., Gómez, K., & Ambrose, C. G. (2018) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2018.01.009 · Cited by 10
Molecular prophage typing ofStaphylococcus aureusisolates from bovine mastitis
Ko, D.-S., Seong, W.-J., Kim, D., Kim, E.-K., Kim, N., Lee, C.-Y., Kim, J., & Kwon, H. (2018) · Journal of Veterinary Science · doi:10.4142/jvs.2018.19.6.771 · Cited by 10
Diffusion, Mixing, and Associated Dye Effects in DNA-Microarray Hybridizations
Borden, J. R., Paredes, C. J., & Papoutsakis, E. T. (2005) · Biophysical Journal · doi:10.1529/biophysj.105.067934 · Cited by 10
Comparison of complete rpoB gene sequence typing and multi-locus sequence typing for phylogenetic analysis of Staphylococcus aureus
Seong, W.-J., Kim, J., & Kwon, H. (2013) · The Journal of General and Applied Microbiology · doi:10.2323/jgam.59.335 · Cited by 9
In Silico Genome-Scale Analysis of Molecular Mechanisms Contributing to the Development of a Persistent Infection with Methicillin-Resistant Staphylococcus aureus (MRSA) ST239
Дмитренко, О. А., Chaplin, A., Александровна, Б. А., Pkhakadze, T. Y., & Alkhovsky, S. V. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232416086 · Cited by 7
Genomic characterization of Staphylococcus aureus from Canastra Minas Artisanal Cheeses
Pineda, A. P. A., Cueva, C. L. R., Chacón, R. D., Ramírez, M., de Almeida, O. G. G., de Oliveira, D. P., Franco, B. D. G. D. M., Lacorte, G. A., Landgraf, M., Silva, N. C. C., et al. (2023) · Brazilian Journal of Microbiology · doi:10.1007/s42770-023-01099-8 · Cited by 8
Biofilms and Aseptic Loosening
Smeltzer, M. S., Nelson, C. L., & Evans, R. P. (2008) · Springer series on biofilms · doi:10.1007/978-3-540-68119-9_3 · Cited by 10
Studying Bacterial Genome Dynamics Using Microarray-Based Comparative Genomic Hybridization
Taboada, E. N., Luebbert, C., & Nash, J. H. E. (2007) · Methods in molecular biology · doi:10.1007/978-1-59745-515-2_15 · Cited by 8
Oligonucleotide and DNA Microarrays: Versatile Tools for Rapid Bacterial Diagnostics
KOSTIC, T. M., François, P., Bodrossy, L., & Schrenzel, J. (2008) · Springer eBooks · doi:10.1007/978-0-387-75113-9_23 · Cited by 8
Genome Content Determination in Methicillin-Resistant Staphylococcus Aureus
François, P., Hernández, D., & Schrenzel, J. (2007) · Future Microbiology · doi:10.2217/17460913.2.2.187 · Cited by 8
Introduction to Microarray‐Based Detection Methods
Schrenzel, J., KOSTIC, T. M., Bodrossy, L., & François, P. (2009) · doi:10.1002/9783527626687.ch1 · Cited by 7
Mechanistic insights into the pathogenesis and therapeutic recalcitrance of Staphylococcus aureus osteomyelitis
Beenken, K. E., Campbell, M. J., Reyes-Pardo, H., O’Brien, C. A., & Smeltzer, M. S. (2026) · Clinical Microbiology Reviews · doi:10.1128/cmr.00259-25 · Cited by 8
Dysregulation of Cell Envelope Homeostasis in Staphylococcus aureus Exposed to Solvated Lignin
Grossman, A. B., Vermerris, W., & Rice, K. C. (2022) · Applied and Environmental Microbiology · doi:10.1128/aem.00548-22 · Cited by 5
Staphylococcus aureus Binding Proteins for Prevention of Orthopaedic Implant-Related Infections
Ratcliffe, E. (2014) · Journal of Microbial & Biochemical Technology · doi:10.4172/1948-5948.1000160 · Cited by 5
Lignin solvated in zwitterionic Good's buffers displays antibacterial synergy against Staphylococcus aureus
Grossman, A. B., Rice, K. C., & Vermerris, W. (2020) · Journal of Applied Polymer Science · doi:10.1002/app.49107 · Cited by 5
IsaB, a new immunoglobulin-binding protein from Staphylococcus aureus
Clark, E. A., Upadhyay, A. K., Bagby, S., & van den Elsen, J. M. H. (2009) · Molecular Immunology · doi:10.1016/j.molimm.2009.05.232 · Cited by 3
Staphylococcus Infection Associated with Arthroplasty
Ye, W., Shang, W., & Yang, Y. (2012) · InTech eBooks · doi:10.5772/25783 · Cited by 2
Genome Comparisons of Diverse Staphylococcus aureus Strains
Mcgavin, M. J. (2006) · Humana Press eBooks · doi:10.1007/978-1-59745-152-9_11 · Cited by 1

Authors: Cassat, J. E., Dunman, P. M., McAleese, F., Murphy, E., Projan, S. J., & Smeltzer, M. S.
Affiliations: University of Arkansas for Medical Sciences (US)
Wyeth (US)
Wyeth Research, Cambridge, Massachusetts
Corresponding author: Smeltzer, Mark S.
ORCID: Cassat, James E.
Dunman, Paul M.
Smeltzer, Mark S.
Venue: Journal of Bacteriology
Publisher: American Society for Microbiology
Published: 2005-01-15
Volume: 187
Issue: 2
Pages: 576-592
ISSN: 0021-9193 (ISSN-L)
1098-5530
DOI: 10.1128/jb.187.2.576-592.2005
PMC: PMC543526
OpenAlex: W2061688904
Cited by: 112
References: 70
Citations by year: 2026: 1 · 2025: 1 · 2024: 2 · 2023: 2 · 2022: 4 · 2021: 2 · 2020: 3 · 2019: 2 · 2018: 3 · 2017: 3 · 2016: 7 · 2015: 8 · 2014: 5 · 2013: 4 · 2012: 8
FWCI: 7.68
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: journals.asm.org/non-commercial-tdm-license (tdm)
Locations: Journal of Bacteriology (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute of Allergy and Infectious Diseases (R01AI043356)
Topics: Health Sciences › Medicine › Infectious Diseases › Antimicrobial Resistance in Staphylococcus
Health Sciences › Medicine › Infectious Diseases › Streptococcal Infections and Treatments
Health Sciences › Medicine › Surgery › Orthopedic Infections and Treatments
Keywords: Staphylococcus aureus, bone and joint infections, comparative genomics, EMRSA-16, SART, strain phylogeny, virulence genes
MeSH terms: Antigens, Bacterial, Bacterial Proteins, DNA-Binding Proteins, DNA, Bacterial, Genes, Bacterial, Nucleic Acid Hybridization, Phylogeny, Repressor Proteins, Staphylococcal Infections, Staphylococcus aureus, Genome, Bacterial, Muscle, Skeletal, Adhesins, Bacterial, Genomics

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Comparative Genomics of Staphylococcus aureus Musculoskeletal Isolates

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks