Cited by 145Tuberculosis Research and EpidemiologyDiagnosis and treatment of tuberculosisInfectious Diseases and Tuberculosis

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Comparison of Two Molecular Methods for Rapid Diagnosis of Extrapulmonary Tuberculosis

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Causse, Manuel, Ruiz, Pilar, Gutiérrez-Aroca, Juan Bautista, Casal, Manuel·2011·Journal of Clinical Microbiology

DOI 10.1128/jcm.00491-11PMC PMC3147762

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Abstract

Application of real-time PCR for the detection of Mycobacterium tuberculosis enables results to be obtained in about 2 h. A total of 340 nonrespiratory samples were processed using two real-time PCR assay kits: Xpert MTB/RIF and Cobas TaqMan MTB. The sensitivity and specificity of the Xpert assay were 95% and 100%, respectively, compared to 78% and 98% for the Cobas assay.

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Authors: Causse, M., Ruiz, P., Gutiérrez-Aroca, J. B., & Casal, M.
Affiliations: Hospital Universitario Reina Sofía (ES)
University of Córdoba (ES)
ORCID: Causse, Manuel
Ruiz, Pilar
Venue: Journal of Clinical Microbiology
Publisher: American Society for Microbiology
Published: 2011-08
Volume: 49
Issue: 8
Pages: 3065-3067
ISSN: 0095-1137 (ISSN-L)
1098-660X
DOI: 10.1128/jcm.00491-11
PMC: PMC3147762
OpenAlex: W2135290191
Semantic Scholar: c1f0f61431f4e037c237ffcb6ced774fc51958b0
Cited by: 145
References: 14
Citations by year: 2024: 4 · 2023: 5 · 2022: 2 · 2021: 15 · 2020: 8 · 2019: 9 · 2018: 8 · 2017: 7 · 2016: 5 · 2015: 19 · 2014: 20 · 2013: 21 · 2012: 16
FWCI: 13.59
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: journals.asm.org/non-commercial-tdm-license (tdm)
Locations: Journal of Clinical Microbiology (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (submittedVersion, cc-by-nc-nd)
Universidad de Córdoba Insitutional Repository (Universidad de Córdoba) (submittedVersion, cc-by-nc-nd)
Topics: Health Sciences › Medicine › Infectious Diseases › Tuberculosis Research and Epidemiology
Health Sciences › Medicine › Infectious Diseases › Diagnosis and treatment of tuberculosis
Health Sciences › Medicine › Infectious Diseases › Infectious Diseases and Tuberculosis
Keywords: extrapulmonary tuberculosis, Mycobacterium tuberculosis detection, real-time PCR, Xpert MTB/RIF, sensitivity and specificity, rapid molecular diagnostics
MeSH terms: Adolescent, Adult, Aged, Aged, 80 and over, Bacteriological Techniques, Child, Child, Preschool, Female, Humans, Male, Middle Aged, Mycobacterium tuberculosis, Sensitivity and Specificity, Tuberculosis, Molecular Diagnostic Techniques, Young Adult

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Comparison of Two Molecular Methods for Rapid Diagnosis of Extrapulmonary Tuberculosis

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