The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
Discovery of a New Capsular Serotype (6C) within Serogroup 6 of Streptococcus pneumoniae
Open accessAbstract
Using two monoclonal antibodies, we found subtypes among pneumococcal isolates that are typed as serotype 6A by the quellung reaction. The prevalent subtype bound to both monoclonal antibodies and was labeled here 6Aα, whereas the minor subtype bound to only one monoclonal antibody and was labeled 6Aβ. To determine the biochemical nature of the two serologically defined subtypes, we purified capsular polysaccharides (PSs) from the two subtypes and examined their chemical structures with gas-liquid chromatography and mass spectrometry. The study results for 6Aα PS are consistent with the previously published structure of 6A PS, which is →2) galactose (1→3) glucose (1→3) rhamnose (1→3) ribitol (5→phosphate. In contrast, the 6Aβ PS study results show that its repeating unit is →2) glucose 1 (1→3) glucose 2 (1→3) rhamnose (1→3) ribitol (5→phosphate. We propose to continue referring to 6Aα as serotype 6A but to refer to 6Aβ as serotype 6C. Serotype 6C would thus represent the 91st pneumococcal serotype, with 90 pneumococcal serotypes having previously been recognized. This study also demonstrates that a new serotype may exist within an established and well-characterized serogroup or serotype.
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Sustained Reductions in Invasive Pneumococcal Disease in the Era of Conjugate Vaccine
Pilishvili, T., Lexau, C., Farley, M. M., Hadler, J., Harrison, L. H., Bennett, N. M., Reingold, A., Thomas, A., Schaffner, W., Craig, A. S., et al. (2010) · The Journal of Infectious Diseases · doi:10.1086/648593 · Cited by 1,311
Pneumococcal Capsules and Their Types: Past, Present, and Future
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Self-citationSecondary bacterial infections associated with influenza pandemics
Morris, D. E., Cleary, D. W., & Clarke, S. C. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.01041 · Cited by 576
Effect of Pneumococcal Conjugate Vaccine on Pneumococcal Meningitis
Hsu, H. E., Shutt, K. A., Moore, M. R., Beall, B. W., Bennett, N. M., Craig, A. S., Farley, M. M., Jorgensen, J. H., Lexau, C. A., Petit, S., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0800836 · Cited by 497
Carvalho, M. D. G., Pimenta, F. C., Jackson, D., Roundtree, A., Ahmad, Y., Millar, E. V., O'Brien, K. L., Whitney, C. G., Cohen, A. L., & Beall, B. W. (2010) · Journal of Clinical Microbiology · doi:10.1128/jcm.02243-09 · Cited by 263
Metadata
- Authors
- Park, I. H., Pritchard, D. G., Cartee, R., Brandao, A., Brandileone, M. C. C., & Nahm, M. H.
- Venue
- Journal of Clinical Microbiology
- Publisher
- American Society for Microbiology
- Published
- 2007-04
- Volume
- 45
- Issue
- 4
- Pages
- 1225-1233
- ISSN
- 0095-1137 (ISSN-L)
- 1098-660X
- OpenAlex
- W2000499723
- Cited by
- 428
- References
- 20
- FWCI
- 30.78
- Type
- journal article
- Language
- en
- Open access
- green
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- Park, I. H., Pritchard, D. G., Cartee, R., Brandao, A., Brandileone, M. C. C., & Nahm, M. H. (2007). Discovery of a New Capsular Serotype (6C) within Serogroup 6 of Streptococcus pneumoniae. Journal of Clinical Microbiology. https://doi.org/10.1128/jcm.02199-06
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