The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Tracheal tube biofilm as a source of bacterial colonization of the lung
Open accessAbstract
Biofilm formation in tracheal tubes, its bacterial content, and its interaction with ventilator gas flow were investigated. At least 50 mg (dry weight) of biofilm was found in 30 of 40 tracheal tubes used in intensive care patients for 2 h to 10 days. Electron microscopy showed bacteria in this layer, and quantitative studies showed that bacterial counts could reach up to 10(6)/cm of tube length. Bacteria were cultured from the patient side of 18 of 78 heat and moisture exchanger-microbiological filter units removed from ventilator circuits. Particles were shown to detach from tracheal tube luminal biofilm and were projected up to 45 cm from the tracheal tube tip. Following contamination of the tracheal tube biofilm with a patient's own gastrointestinal flora, entrainment of bacteria in the inspiratory gas flow provides a mechanism for initial and repeated lung colonization.
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DUMOULIN, G. (1982) · The Lancet · doi:10.1016/s0140-6736(82)90974-6 · Cited by 468
Cited by
ESCMID∗ guideline for the diagnosis and treatment of biofilm infections 2014
Høiby, N., Bjarnsholt, T., Moser, C., Bassi, G. L., Coenye, T., Donelli, G., Hall-Stoodley, L., Holá, V., Imbert, C., Kirketerp-Møller, K., et al. (2015) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2014.10.024 · Cited by 726
Candida biofilms on implanted biomaterials: a clinically significant problem
Ramage, G., MartÃnez, J. P., & López-Ribot, J. L. (2006) · FEMS Yeast Research · doi:10.1111/j.1567-1364.2006.00117.x · Cited by 575
Ventilator-Associated Pneumonia
(2012) · SpringerReference · doi:10.1007/springerreference_225126 · Cited by 406
Viscoelasticity of biofilms and their recalcitrance to mechanical and chemical challenges
Peterson, B. W., He, Y., Ren, Y., Zerdoum, A., Libera, M. R., Sharma, P. K., van Winkelhoff, A.-J., Neut, D., Stoodley, P., van der Mei, H. C., et al. (2015) · FEMS Microbiology Reviews · doi:10.1093/femsre/fuu008 · Cited by 346
RISK FACTORS FOR NOSOCOMIAL PNEUMONIA
Fleming, C. A., Balaguera, H. U., & Craven, D. E. (2001) · Medical Clinics of North America · doi:10.1016/s0025-7125(05)70395-3 · Cited by 46
Metadata
- Authors
- Inglis, T. J., Millar, M. R., Jones, J. G., & Robinson, D. A.
- Venue
- Journal of Clinical Microbiology
- Publisher
- American Society for Microbiology
- Published
- 1989-09
- Volume
- 27
- Issue
- 9
- Pages
- 2014-2018
- ISSN
- 0095-1137 (ISSN-L)
- 1098-660X
- OpenAlex
- W1896237789
- Cited by
- 218
- References
- 1
- FWCI
- 2.00
- Type
- journal article
- Language
- en
- Open access
- green
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- Inglis, T. J., Millar, M. R., Jones, J. G., & Robinson, D. A. (1989). Tracheal tube biofilm as a source of bacterial colonization of the lung. Journal of Clinical Microbiology. https://doi.org/10.1128/jcm.27.9.2014-2018.1989
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