Discovery and Genomic Characterization of a Novel Henipavirus, Angavokely Virus, from Fruit Bats in Madagascar
Open accessPublished version of a preprint
Abstract
Henipaviruses include highly pathogenic emerging zoonotic viruses, derived from bat, rodent, and shrew reservoirs. Bat-borne Hendra (HeV) and Nipah (NiV) are the most well-known henipaviruses, for which no effective antivirals or vaccines for humans have been described.
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Cites
Highly accurate protein structure prediction with AlphaFold
Jumper, J., Evans, R., Pritzel, A., Green, T., Figurnov, M., Ronneberger, O., Tunyasuvunakool, K., Bates, R., Žídek, A., Potapenko, A., et al. (2021) · Nature · doi:10.1038/s41586-021-03819-2 · Cited by 43,764 · see citing works
Posterior summarization in Bayesian phylogenetics using tracer 1.7
Rambaut, A., Drummond, A. J., Xie, D., Baele, G., & Suchard, M. A. (2018) · Systematic Biology · doi:10.1093/sysbio/syy032 · Cited by 11,159 · see citing works
BEAST 2: a software platform for Bayesian evolutionary analysis
Bouckaert, R., Heled, J., Kühnert, D., Vaughan, T., Wu, C.-H., Xie, D., Suchard, M. A., Rambaut, A., & Drummond, A. J. (2014) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1003537 · Cited by 6,527 · see citing works
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- Authors
- Madera, S., Kistler, A., Ranaivoson, H. C., Ahyong, V., Andrianiaina, A., Andry, S., Raharinosy, V., Randriambolamanantsoa, T. H., Ravelomanantsoa, N. A. F., Tato, C. M., DeRisi, J. L., Aguilar, H. C., Lacoste, V., Dussart, P., Heraud, J.-M., & Brook, C. E.
- Affiliations
- University of California, San Francisco (US)
- Chan Zuckerberg Biohub San Francisco (US)
- University of Antananarivo (MG)
- Institut Pasteur de Madagascar (MG)
- Cornell University (US)
- Virology Unit, Institut Pasteur de Madagascar, Antananarivo, Madagascar
- University of Chicago (US)
- Corresponding author
- Brook, Cara E.
- ORCID
- Venue
- Journal of Virology
- Publisher
- American Society for Microbiology
- Published
- 2022-09-28
- Volume
- 96
- Issue
- 18
- Pages
- e0092122-e0092122
- ISSN
- 0022-538X (ISSN-L)
- 1098-5514
- PMC
- PMC9517717
- OpenAlex
- W4293567372
- Cited by
- 74
- References
- 3
- Citations by year
- 2026: 15 · 2025: 19 · 2024: 22 · 2023: 15 · 2022: 3
- FWCI
- 10.65
- Type
- journal article
- Language
- en
- Open access
- green
- doi.org
- Licence
- Locations
- Journal of Virology (publishedVersion)
- bioRxiv (Cold Spring Harbor Laboratory) (acceptedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion, cc-by)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- HHS | National Institutes of Health (1R01AI129822-01, 5T32AI007641-19, R01AI109022)
- DOD | DARPA | Defense Sciences Office, DARPA (D18AC00031)
- Bill and Melinda Gates Foundation (OPP1211841)
- Adolph C. and Mary Sprague Miller Institute for Basic Research in Science, University of California Berkeley (fellowship)
- Branco Weiss Fellowship – Society in Science (fellowship)
- Chan Zuckerberg Biohub (GCE OPP1211841)
- American Association for the Advancement of Science (Loréal, USA For Women in Science Fellowship)
- Topics
- Health Sciences › Medicine › Epidemiology › Virology and Viral Diseases
- Health Sciences › Medicine › Infectious Diseases › Viral Infections and Outbreaks Research
- Health Sciences › Medicine › Infectious Diseases › Viral Infections and Vectors
- Keywords
- henipaviruses, novel virus discovery, Pteropodidae, zoonotic viruses, Hendra virus, Nipah virus, bat viruses, viral entry pathways, interspecies transmission, emerging zoonoses, Madagascar
- MeSH terms
- Animals, Chiroptera, Glycoproteins, Humans, Madagascar, Phylogeny, Urine, Zoonoses, Genome, Viral, Henipavirus, Nipah Virus, Henipavirus Infections
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