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Cited by 11Protein Tyrosine PhosphatasesVirus-based gene therapy researchT-cell and B-cell Immunology

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Enforced Dimerization of CD45 by the Adenovirus E3/49K Protein Inhibits T Cell Receptor Signaling

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Windheim, Mark, Reubold, Thomas F., Aichane, Khadija, Gaestel, Matthias, Burgert, Hans-Gerhard·2023·Journal of Virology
DOI 10.1128/jvi.01898-22PMC PMC10231199

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Abstract

The battle between viruses and their hosts is an ongoing arms race. Whereas the host tries to detect and eliminate the virus, the latter counteracts such antiviral measures to replicate and spread.

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Metadata

Authors
Windheim, M., Reubold, T. F., Aichane, K., Gaestel, M., & Burgert, H.-G.
Affiliations
  • Medizinische Hochschule Hannover (DE)
  • University of Freiburg (DE)
Corresponding author
Windheim, Mark
ORCID
Venue
Journal of Virology
Publisher
American Society for Microbiology
Published
2023-05-31
Volume
97
Issue
5
Pages
e0189822-e0189822
ISSN
  • 0022-538X (ISSN-L)
  • 1098-5514
DOI
10.1128/jvi.01898-22
PMC
PMC10231199
OpenAlex
W4367600703
Cited by
11
References
2
Citations by year
2026: 6 · 2024: 3 · 2023: 2
FWCI
0.98
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of Virology (publishedVersion)
  • bioRxiv (Cold Spring Harbor Laboratory) (acceptedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • University of Pittsburgh
  • Medizinischen Hochschule Hannover
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Tyrosine Phosphatases
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Virus-based gene therapy research
  • Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
Keywords
CD45, protein dimerization, protein tyrosine phosphatase inhibition, T cell receptor signaling, viral immune evasion, intrinsically disordered regions, autoimmune disease therapy, graft rejection prevention
MeSH terms
Adenoviridae, Adenoviruses, Human, Humans, Receptors, Antigen, T-Cell, Leukocyte Common Antigens, Adenovirus E3 Proteins, Dimerization

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