The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
Characterization of adenovirus-associated virus-induced polypeptides in KB cells
Open accessAbstract
Electrophoretic analysis of KB cells coinfected with adenovirus-associated virus (AAV) type 2, a defective parvovirus, and adenovirus type 5 (as helper) have revealed the synthesis in vivo of at least five AAV-specific polypeptides. The three largest polypeptides, with molecular weights of 90,700, 71,600, and 60,000 comigrated in polyacrylamide gels with the three AAV structural polypeptides. The remaining two polypeptides had molecular weights of 24,900 and 15,800. The concentrations of the AAV-induced polypeptides relative to one another remained approximately constant during the infectious cycle, and the structural components were present in proportions similar to those found in purified virions. As determined by pulse-chase experiments, all polypeptides were generated at the level of protein synthesis and not by posttranslational proteolytic processing. Although inhibitors of proteolytic enzymes failed to influence the pattern of AAV-induced polypeptides, and amino acid analog, L-canavanine, blocked the appearances of both the major structural polypeptide (60,000 daltons) and the larger nonstructural polypeptide (24,900 daltons). Taken in conjunction with pulse-chase data, this result supports a model whereby the major virion polypeptide is produced by proteolytic cleavage of the nascent polypeptide chain.
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“The AAV capsid is composed of 60 subunits of the overlapping VP1:VP2:VP3, in an approximate ratio of 1:1:10, assembled with T = 1 icosahedral symmetry and a diameter of approximately 260 Å [13,14].”
From Understanding Capsid Assembly and Genome Packaging for Adeno-Associated Viruses (2017) · cites this paper as [14]
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Cites
Weber, K., & Osborn, M. (1969) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)94333-4 · Cited by 16,688
Analysis of bacteriophage T7 early RNAs and proteins on slab gels
Studier, F. W. (1973) · Journal of Molecular Biology · doi:10.1016/0022-2836(73)90003-x · Cited by 2,215
Processing of Adenovirus 2-Induced Proteins
Anderson, C. W., Baum, P. R., & Gesteland, R. F. (1973) · Journal of Virology · doi:10.1128/jvi.12.2.241-252.1973 · Cited by 755
Polypeptide cleavages in the formation of poliovirus proteins.
Jacobson, M. F., & Baltimore, D. (1968) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.61.1.77 · Cited by 350
Messenger RNA for the coat protein of tobacco mosaic virus
Hunter, T. R., Hunt, T., Knowland, J., & Zimmern, D. (1976) · Nature · doi:10.1038/260759a0 · Cited by 262
Selection and Preliminary Characterization of Temperature-Sensitive Mutants of Type 5 Adenovirus
Ensinger, M. J., & Ginsberg, H. S. (1972) · Journal of Virology · doi:10.1128/jvi.10.3.328-339.1972 · Cited by 244
Marsden, H. S., Crombie, I. K., & Subak-Sharpe, J. H. (1976) · Journal of General Virology · doi:10.1099/0022-1317-31-3-347 · Cited by 207
Structural Proteins of Adenovirus-Associated Viruses
Rose, J. A., Maizel, J. V., Inman, J. K., & Shatkin, A. J. (1971) · Journal of Virology · doi:10.1128/jvi.8.5.766-770.1971 · Cited by 193
Self-citationRose, J. A., Berns, K. I., Hoggan, M. D., & Koczot, F. J. (1969) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.64.3.863 · Cited by 179
Self-citationTranslation of Sindbis virus 26 S RNA and 49 S RNA in lysates of rabbit reticulocytes
Simmons, D. T., & Strauss, J. H. (1974) · Journal of Molecular Biology · doi:10.1016/0022-2836(74)90027-8 · Cited by 144
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Characterization of Heavy Particles of Adeno-associated Virus Type 1
Lipps, B. V., & Mayor, H. D. (1982) · Journal of General Virology · doi:10.1099/0022-1317-58-1-63 · Cited by 8
Animal Parvoviruses: Comparative Aspects and Diagnosis
Kurstak, E., & Tijssen, P. (1981) · Elsevier eBooks · doi:10.1016/b978-0-12-429703-6.50007-8 · Cited by 6
Lederman, M., Shull, B. C., Stout, E. R., & Bates, R. C. (1987) · Journal of General Virology · doi:10.1099/0022-1317-68-1-147 · Cited by 6
Research Status and Applications of Adeno‐Associated Virus
Xia, K., Liu, S., Wu, Z., & Jiang, J. (2024) · ChemBioChem · doi:10.1002/cbic.202400856 · Cited by 4
Adeno-associated Virus as a Mammalian DNA Vector
Salganik, M., Hirsch, M. L., & Samulski, R. J. (2015) · ASM Press eBooks · doi:10.1128/9781555819217.ch37 · Cited by 5
Recombinant Adeno-associated Virus Vectors
Muramatsu, S. (1998) · Japanese Journal of Thrombosis and Hemostasis · doi:10.2491/jjsth.9.13 · Cited by 4
Cellular response to adenovirus and adeno- associated virus coinfection.
Bevington, J. M. (2009) · OhioLink ETD Center (Ohio Library and Information Network)
UNDERSTANDING THE SOLUTION-PHASE BIOPHYSICS AND CONFORMATIONAL DYNAMICS OF VIRUS CAPSIDS
Rayaprolu, V. (2013) · Montana State University ScholarWorks (Montana State University)
Nicolson, S. C. (2014) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/gbv4-z740
Tissue Tropisms of AAV Vectors Deficient in Receptor Binding
Crumrine, J. K. (2005) · The Knowledge Bank (The Ohio State University)
Metadata
- Authors
- Buller, R. M., & Rose, J. A.
- Venue
- Journal of Virology
- Publisher
- American Society for Microbiology
- Published
- 1978-01
- Volume
- 25
- Issue
- 1
- Pages
- 331-338
- ISSN
- 0022-538X (ISSN-L)
- 1098-5514
- PMC
- PMC353931
- OpenAlex
- W1517847098
- Cited by
- 111
- References
- 24
- Citations by year
- 2025: 2 · 2024: 6 · 2023: 11 · 2022: 2 · 2021: 8 · 2020: 5 · 2019: 2 · 2018: 1 · 2017: 4 · 2016: 2 · 2015: 3 · 2014: 4 · 2013: 3 · 2012: 2
- FWCI
- 4.92
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Journal of Virology (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Parvovirus B19 Infection Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Virus-based gene therapy research
- Health Sciences › Medicine › Epidemiology › Virology and Viral Diseases
- Keywords
- KB cells, proteolytic processing, L-canavanine, pulse-chase labeling, viral protein synthesis, infectious cycle
- MeSH terms
- Adenoviruses, Human, Canavanine, Cell Line, Humans, Molecular Weight, Parvoviridae, Peptide Biosynthesis, Phenylmethylsulfonyl Fluoride, Satellite Viruses, Tosyllysine Chloromethyl Ketone, Tosylphenylalanyl Chloromethyl Ketone, Viral Proteins, Virus Replication
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