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Murine Sarcoma and Leukemia Viruses: Assay Using Clonal Lines of Contact-Inhibited Mouse Cells
Open accessAbstract
A continuous cell line of highly contact-inhibited cells (NIH/3T3) has been developed from NIH Swiss mouse embryo cultures. Its growth properties are similar to those of 3T3 and BALB/3T3. Although 3T3 is relatively insensitive to focus formation by murine sarcoma viruses, cloned lines of both NIH/3T3 and BALB/3T3 have been isolated that are highly sensitive to sarcoma virus focus formation and leukemia virus growth. The sensitivity and specificity are comparable to those found with primary embryo cells. MSV-transformed lines of NIH/3T3 have been obtained.
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Cited by
Klein, R., Nanduri, V., Jing, S., Lamballe, F., Tapley, P., Bryant, S., Cordon-Cardo, C., Jones, K. R., Reichardt, L. F., & Barbacid, M. (1991) · Cell · doi:10.1016/0092-8674(91)90628-c · Cited by 958
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Cox, A. D., & Der, C. J. (2010) · Small GTPases · doi:10.4161/sgtp.1.1.12178 · Cited by 706
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Pardo, L. A., del Camino, D., Sánchez, A., Alves, F., Brüggemann, A., Beckh, S., & Stühmer, W. (1999) · The EMBO Journal · doi:10.1093/emboj/18.20.5540 · Cited by 446
Embryonic lethal mutation in mice induced by retrovirus insertion into the α1(I) collagen gene
Schnieke, A., Harbers, K., & Jaenisch, R. (1983) · Nature · doi:10.1038/304315a0 · Cited by 417
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Metadata
- Authors
- Jainchill, J. L., Aaronson, S. A., & Todaro, G. J.
- Venue
- Journal of Virology
- Publisher
- American Society for Microbiology
- Published
- 1969-11
- Volume
- 4
- Issue
- 5
- Pages
- 549-553
- ISSN
- 0022-538X (ISSN-L)
- 1098-5514
- OpenAlex
- W1754450379
- Cited by
- 816
- References
- 0
- FWCI
- 6.80
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Murine Sarcoma and Leukemia Viruses: Assay Using Clonal Lines of Contact-Inhibited Mouse Cells. https://app.cochat.ai/papers/10.1128/jvi.4.5.549-553.1969
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- Jainchill, J. L., Aaronson, S. A., & Todaro, G. J. (1969). Murine Sarcoma and Leukemia Viruses: Assay Using Clonal Lines of Contact-Inhibited Mouse Cells. Journal of Virology. https://doi.org/10.1128/jvi.4.5.549-553.1969
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
