Cited by 304Respiratory viral infections researchVirology and Viral DiseasesInfluenza Virus Research Studies

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Infection of Ciliated Cells by Human Parainfluenza Virus Type 3 in an In Vitro Model of Human Airway Epithelium

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Zhang, Liqun, Bukreyev, Alexander, Thompson, Catherine I., Watson, Brandy, Peeples, Mark E., Collins, Peter L., Pickles, Raymond J.·2005·Journal of Virology

DOI 10.1128/jvi.79.2.1113-1124.2005PMC PMC538579

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Abstract

We constructed a human recombinant parainfluenza virus type 3 (rPIV3) that expresses enhanced green fluorescent protein (GFP) and used this virus, rgPIV3, to characterize PIV3 infection of an established in vitro model of human pseudostratified mucociliary airway epithelium (HAE). The apical surface of HAE was highly susceptible to rgPIV3 infection, whereas only occasional cells were infected when virus was applied to the basolateral surface. Infection involved exclusively ciliated epithelial cells. There was little evidence of virus-mediated cytopathology and no spread of the virus beyond the ciliated cell types. Infection of ciliated cells by rgPIV3 was sensitive to a neuraminidase specific for α2-6-linked sialic acid residues, but not to a neuraminidase that cleaves α2-3- and α2-8-linked sialic acid residues. This provided evidence that rgPIV3 utilizes α2-6-linked sialic acid residues for initiating infection, a specificity also described for human influenza viruses. The PIV3 fusion (F) glycoprotein was trafficked exclusively to the apical surface of ciliated cells, which also was the site of release of progeny virus. F glycoprotein localized predominately to the membranes of the cilial shafts, suggesting that progeny viruses may bud from cilia per se. The polarized trafficking of F glycoprotein to the apical surface also likely restricts its interaction with neighboring cells and could account for the observed lack of cell-cell fusion. HAE derived from cystic fibrosis patients was not more susceptible to rgPIV3 infection but did exhibit limited spread of virus due to impaired movement of lumenal secretions due to compromised function of the cilia.

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Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase.
Fuerst, T. R., Niles, E. G., Studier, F. W., & Moss, B. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.21.8122 · Cited by 2,078
Membrane-Associated Heparan Sulfate Proteoglycan Is a Receptor for Adeno-Associated Virus Type 2 Virions
Summerford, C., & Samulski, R. J. (1998) · Journal of Virology · doi:10.1128/jvi.72.2.1438-1445.1998 · Cited by 1,409
Evidence for Periciliary Liquid Layer Depletion, Not Abnormal Ion Composition, in the Pathogenesis of Cystic Fibrosis Airways Disease
Matsui, H., Grubb, B. R., Tarran, R., Randell, S. H., Gatzy, J. T., Davis, C. W., & Boucher, R. C. (1998) · Cell · doi:10.1016/s0092-8674(00)81724-9 · Cited by 1,168
Evidence for Budding of Human Immunodeficiency Virus Type 1 Selectively from Glycolipid-Enriched Membrane Lipid Rafts
Nguyen, D., & Hildreth, J. E. K. (2000) · Journal of Virology · doi:10.1128/jvi.74.7.3264-3272.2000 · Cited by 788
Human and avian influenza viruses target different cell types in cultures of human airway epithelium
Matrosovich, M. N., Matrosovich, T. Y., Gray, T. E., Roberts, N. A., & Klenk, H. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308001101 · Cited by 777
Respiratory Syncytial Virus Infection of Human Airway Epithelial Cells Is Polarized, Specific to Ciliated Cells, and without Obvious Cytopathology
Zhang, L., Peeples, M. E., Boucher, R. C., Collins, P. L., & Pickles, R. J. (2002) · Journal of Virology · doi:10.1128/jvi.76.11.5654-5666.2002 · Cited by 583
Self-citation
Developmental changes in heparan sulfate expression: in situ detection with mAbs.
David, G., Bai, X. M., der Schueren, B. V., Cassiman, J. J., & BERGHE, H. V. D. (1992) · The Journal of Cell Biology · doi:10.1083/jcb.119.4.961 · Cited by 479
Pathological changes in virus infections of the lower respiratory tract in children
Aherne, W., Bird, T., Court, S., Gardner, P. S., & McQuillin, J. (1970) · Journal of Clinical Pathology · doi:10.1136/jcp.23.1.7 · Cited by 450
Paramyxovirus Fusion: A Hypothesis for Changes
Lamb, R. A. (1993) · Virology · doi:10.1006/viro.1993.1561 · Cited by 420
Coordinated clearance of periciliary liquid and mucus from airway surfaces.
Matsui, H., Randell, S. H., Peretti, S. W., Davis, C. W., & Boucher, R. C. (1998) · Journal of Clinical Investigation · doi:10.1172/jci2687 · Cited by 397

Show all 50 references

Research works printed but not linked: 4

Chanock R. M. B. R. Murphy and P. L. Collins. 2001. Parainfluenza viruses p. 1341-1380. In D. M. Knipe and P. M. Howley (ed.) Fields virology 4th ed. vol. 1. Lippincott Williams & Wilkins Philadelphia Pa.
Collins P. L. R. M. Chanock and B. R. Murphy. 2001. Respiratory syncytial virus p. 1443-1485. In D. M. Knipe and P. M. Howley (ed.) Fields virology 4th ed. vol. 1. Lippincott Williams & Wilkins Philadelphia Pa.
Lamb R. and D. Kolakofsky. 1996. Paramyxoviridae: the viruses and their replication p. 1305-1340. In D. M. Knipe and P. M. Howley (ed.) Fields virology 4th ed. vol. 1. Lippincott Williams & Wilkins Philadelphia Pa.
Lamb R. A. and R. M. Krug. 2001. Orthomyxoviridae : the viruses and their replication p. 1487-1579. In D. M. Knipe and P. M. Howley (ed.) Fields virology 4th ed. vol. 1. Lippincott Williams and Wilkins Philadelphia Pa.

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Kitai, Y., Kojima, S., Aishajiang, A., Kawase, M., Watanabe, O., Yabukami, H., Hashimoto, R., Akahori, Y., Katoh, H., Takayama, K., et al. (2025) · Journal of General Virology · doi:10.1099/jgv.0.002131 · Cited by 1
Human Parainfluenza Virus Infections
Beck, E. T., & Henrickson, K. J. (2014) · CRC Press eBooks · doi:10.1201/b16778-23 · Cited by 1
소아에서 파라인플루엔자 바이러스 4형의 역학 및 임상 양상에 대한 단일기관 연구: 2015–2017
손, 영., 최, 윤., 윤, 기., 최, 은., & 이, 환. (2018) · Pediatric Infection & Vaccine · Cited by 1
MiRNAs and tumor suppressors form a gene regulatory network to protect multiciliogenesis
Wildung, M. (2019) · eDiss (Georg-August-Universität Göttingen) · doi:10.53846/goediss-7225 · Cited by 1
Establishment of primary transgenic human airway epithelial cell cultures to study respiratory virus – host interactionsPreprint
Jónsdóttir, H. R., Marti, S., Geerts, D., Rodriguez, R., Thiel, V., & Dijkman, R. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/694380 · Cited by 1
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Oakland, M., McCray, P. B., Maury, W. J., Davidson, B. L., Klingelhutz, A. J., & Perlman, S. M. (2013) · doi:10.17077/etd.f63i1jvz
Diversidade genética dos Vírus Parainfluenza 1, 2 e 3, identificados em amostras colhidas no Hospital Universitário da Universidade de São Paulo, durante os anos de 1995 a 2005.
Perini, A. P. (2012) · doi:10.11606/t.87.2012.tde-26112012-082543
Identification of host proteins required for vesicular stomatitis virus infection
Panda, D. (2011) · Lincoln (University of Nebraska)
The Use of Reverse Genetics to Clone and Rescue Infectious, Recombinant Human Parainfluenza Type 3 Viruses
Roth, J. (2021) · Digital Commons - USU (Utah State University) · doi:10.26076/852b-9016
CFTR Gene Transfer and Tracking the CFTR Protein in the Airway Epithelium
Gonzalez, G., Boulanger, P. A., & Hong, S. S. (2012) · InTech eBooks · doi:10.5772/30821
Impact of the Non-structural 2 Protein on Respiratory Syncytial Virus Pathogenesis
Liesman, R. M. (2019) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/vnar-qr74
Genetics and Disease Mechanisms
Esther, C. R., & Leigh, M. W. (2008) · Elsevier eBooks · doi:10.1016/b978-032304048-8.50065-7
Myxovirus interaction with the human airway epithelium
Scull, M. A. (2019) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/9k4z-5e11
Infection of differentiated epithelial cells by viruses of the bovine respiratory disease complex
Kirchhoff, J. (2014)
A dual drug regimen synergistically blocks human parainfluenza virus
Dirr, L., El-Deeb, I. M., Altmeyer, R. M., & Guillon, P. (2016)
A single L288I substitution in the fusion protein of bovine parainfluenza virus type 3 enhances virus growth in semi-suitable cell lines
Matsuura, R., Takada, M., Kokuho, T., Tsuboi, T., Kameyama, K., & Takeuchi, K. (2017) · Archives of Virology · doi:10.1007/s00705-017-3378-1
Respiratory Epithelial Cells in Innate Immunity against Respiratory Viruses
Rodriguez-Mier, D., Torres-López, E., Salinas-Carmona, M. C., & Rosas-Taraco, A. G. (2018) · Medicina Universitaria · doi:10.24875/rmu.m18000004
Serological evaluation of precolostral Bovine Parainfluenza 3 Virus infection in an organised dairy herd
Gür, S., Göksu, A. G., & Birdane, F. M. (2020) · Etlik Veteriner Mikrobiyoloji Dergisi · doi:10.35864/evmd.631045
Vírus sincicial respiratório circulantes em pacientes pediátricos: epidemiologia molecular e caracterização genotípica de resistência frente ao Palivizumabe.
Dorlass, E. G. (2020) · doi:10.11606/d.42.2020.tde-04012022-111438
Faculty Opinions recommendation of 4'-Azidocytidine (R1479) inhibits henipaviruses and other paramyxoviruses with high potency.
Horvat, B. (2019) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.730933720.793565840
PI4KIIIβ inhibition reduces rhinovirus associated cell shedding and ciliary dysfunctionPreprint
Velkova, S. A., Petris, A. M., Lee, D. D. H., Cardinale, D., MOULDING, D. A., Williamson, R. A., Beinke, S., Grace, K., Hessel, E. M., Belyaev, N. N., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.12.14.571686
Porcine parainfluenza virus 1: Evaluation of pathogenesis, strain differences, vaccine efficacy, and assay development in nursery pigs
Welch, M. (2021) · doi:10.31274/td-20240329-589
Modeling respiratory viral infections actual in the first quarter of the XXI century: from primary epithelial cultures to organoids
Kuznetsova, T. A., Mikhalko, A. A., Shchelkanov, E. M., Kryzhanovsky, S. P., & Shchelkanov, M. Y. (2025) · Russian Journal of Infection and Immunity · doi:10.15789/2220-7619-mrv-17899
Molecular Mechanisms of Respiratory Syncytial Virus Pathogenesis
Granoski, M. J., Stojic, A., Lee, S. Z., & Marchant, D. (2025) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev-pathmechdis-042424-114052 · Cited by 3
Additional file 2 of Inefficient antiviral response in reconstituted small-airway epithelium from chronic obstructive pulmonary disease patients following human parainfluenza virus type 3 infection
Bondeelle, L., Salmona, M., Houdouin, V., Diaz, E., Dutrieux, J., Mercier‐Delarue, S., Constant, S., Huang, S., Bergeron, A., & LeGoff, J. (2024) · Figshare · doi:10.6084/m9.figshare.25530438
Additional file 3 of Inefficient antiviral response in reconstituted small-airway epithelium from chronic obstructive pulmonary disease patients following human parainfluenza virus type 3 infection
Bondeelle, L., Salmona, M., Houdouin, V., Diaz, E., Dutrieux, J., Mercier‐Delarue, S., Constant, S., Huang, S., Bergeron, A., & LeGoff, J. (2024) · Figshare · doi:10.6084/m9.figshare.26701312
Additional file 1 of Inefficient antiviral response in reconstituted small-airway epithelium from chronic obstructive pulmonary disease patients following human parainfluenza virus type 3 infection
Bondeelle, L., Salmona, M., Houdouin, V., Diaz, E., Dutrieux, J., Mercier‐Delarue, S., Constant, S., Huang, S. X., Bergeron, A., & LeGoff, J. (2024) · Figshare · doi:10.6084/m9.figshare.25530258
Gene Therapy in Nonneoplastic Lung Disease
Allen, T. C., & Cagle, P. T. (2008) · Molecular pathology library · doi:10.1007/978-0-387-72430-0_48
Disruption of goat airway epithelial barrier function by caprine parainfluenza virus type 3 infection in an ALI model
Lei-lei, Y. A. N. G., Min, S. U. N., ZHANG, W.-W., Wang, H.-Y., Cheng, Z.-L., Liu, M., Feng, Z.-X., & Li, W. (2026) · Veterinary Microbiology · doi:10.1016/j.vetmic.2026.110900
RSV Infects the Human Nasal Epithelium via the Basolateral Route with Distinct Subgroup Infectivity and Basal Cell TropismPreprint
Murray, A. M., Nagaraj, D., Schultz, E. M., Aloisio, G. M., Nicholson, E. G., Blutt, S. E., Avadhanula, V., & Piedra, F.-A. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.03.05.709813
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Lotti, V., Lagni, A., Diani, E., Palmisano, A., Cecchetto, R., Tonon, E., Sorio, C., & Gibellini, D. (2026) · Microbiological Research · doi:10.1016/j.micres.2026.128508
Régulation épigénétique du gène CFTR
Bergougnoux, A. (2013) · theses.fr (ABES) · doi:10.70675/96be3b9czbd0az4803za18ez9f92e5e10e5c
Étude de l’infection du système nerveux central par le virus de la rougeole
Welsch, J. (2016) · theses.fr (ABES) · doi:10.70675/12f5ffefzb08dz4362z8980z6420c71e8969
Rôle de l’IL-17 locale dans l’induction de la NETose et l’obstruction pulmonaire au cours la Broncho-Pneumopathie Chronique Obstructive (BPCO).
Fuselier, E. (2021) · theses.fr (ABES) · doi:10.70675/b131a0d2z73c9z4e90za6caz7af5d2a6c329
A rapid yeast-based reverse genetics system reveals SARS-CoV-2 Omicron BA.2.86 variant spreads faster than Omicron JN.1 variant in primary human nasal and bronchial epithelial airway cultures
Xu, J., Chamblee, M., Hsu, C. C., Jiang, F., Chen, P., Zhang, Y., Liang, X., Amer, A. O., Boyaka, P. N., Cormet‐Boyaka, E., et al. (2026) · mBio · doi:10.1128/mbio.00122-26
Self-citation

Authors: Zhang, L., Bukreyev, A., Thompson, C. I., Watson, B., Peeples, M. E., Collins, P. L., & Pickles, R. J.
Affiliations: Cystic Fibrosis/Pulmonary Research and Treatment Center
National Institutes of Health (US)
Abigail Wexner Research Institute (US)
University of North Carolina at Chapel Hill (US)
ORCID: Zhang, Liqun
Bukreyev, Alexander
Peeples, Mark E.
Collins, Peter L.
Pickles, Raymond J.
Venue: Journal of Virology
Publisher: American Society for Microbiology
Published: 2005-01-15
Volume: 79
Issue: 2
Pages: 1113-1124
ISSN: 0022-538X (ISSN-L)
1098-5514
DOI: 10.1128/jvi.79.2.1113-1124.2005
PMC: PMC538579
OpenAlex: W2159953474
Cited by: 302
References: 50
Citations by year: 2026: 12 · 2025: 12 · 2024: 19 · 2023: 13 · 2022: 16 · 2021: 17 · 2020: 19 · 2019: 17 · 2018: 12 · 2017: 9 · 2016: 11 · 2015: 9 · 2014: 16 · 2013: 12 · 2012: 15
FWCI: 6.49
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: journals.asm.org/non-commercial-tdm-license (tdm)
Locations: Journal of Virology (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Carolina Digital Repository (University of North Carolina at Chapel Hill) (submittedVersion)
UNC Libraries
Funders: National Institutes of Health
National Heart, Lung, and Blood Institute (P01HL051818, HL 66943-01, HL 51818-09)
Topics: Health Sciences › Medicine › Epidemiology › Respiratory viral infections research
Health Sciences › Medicine › Epidemiology › Virology and Viral Diseases
Health Sciences › Medicine › Epidemiology › Influenza Virus Research Studies
Keywords: parainfluenza virus type 3, ciliated epithelial cells, airway epithelium, neuraminidase sensitivity, cell-cell fusion, cystic fibrosis
MeSH terms: Bronchi, Cell Differentiation, Cells, Cultured, Cilia, Epithelial Cells, Heparan Sulfate, Heparitin Sulfate, Humans, Neuraminidase, Parainfluenza Virus 3, Human, Trachea, Viral Proteins, Virus Shedding, N-Acetylneuraminic Acid

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Infection of Ciliated Cells by Human Parainfluenza Virus Type 3 in an In Vitro Model of Human Airway Epithelium

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