Characterizations of Three Major Cysteine Sensors of Keap1 in Stress Response
Saito, Ryota, Suzuki, Takafumi, Hiramoto, Keiichiro, Asami, Soichiro, Naganuma, Eriko, Suda, Hiromi, Iso, Tatsuro, Yamamoto, Hirotaka, Morita, Masanobu, Baird, Liam, Furusawa, Yuki, Negishi, Takaaki, Ichinose, Masakazu, Yamamoto, Masayuki·2016·Molecular and Cellular Biology
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- Superoxide Anion Generation, Its Pathological Cellular and Molecular Roles and Pharmacological Targeting in Inflammatory Pain: Lessons from the Potassium Superoxide ModelBeatriz H. S. Bianchini, Geovana Martelossi-Cebinelli, Jessica Aparecida Carneiro, Fernanda Soares Rasquel-Oliveira, Rúbia Casagrande, Waldiceu Aparecido Verri Jr · 2025 · Future Pharmacology
- Identification of novel Nrf2/Keap1 pathway mutations in pediatric acute lymphoblastic leukemiaDilara Fatma Akın, Sedef Hande Aktaş, Mehmet Altay Ünal, Teoman Kankılıç · 2019 · Pediatric Hematology and Oncology
- Nrf2 Activation Ameliorates Hepatotoxicity Induced by a Heme Synthesis InhibitorKeiko Taguchi, Saho Masui, Tohru Itoh, Atsushi Miyajima, Masayuki P. Yamamoto · 2018 · Toxicological Sciences
- The dynamic equilibrium between the protective and toxic effects of matrine in the development of liver injury: a systematic review and meta-analysisWeiyi Feng, Te-chan Kao, Jiajie Jiang, Xinyu Zeng, Shuang Chen, Jinhao Zeng, Yu Chen, Xiao Ma · 2024 · Frontiers in Pharmacology
- The crosstalk between Nrf2 and pyroptosis in diseasesXiaomei Wang, Marzieh Monemi, Fatemeh Mortazavi Moghadam, Ahmad Fazilat, Salomeh Roshani, Mohammad Valilo · 2025 · Pathology - Research and Practice
- Cistanche flavonoids activate the Keap1-Nrf2-ARE signaling pathway in improving cognitive dysfunction in Alzheimer's disease: A reviewRuiqi Zhao, Wanfu Bai, Zhenyu Tian, Xinye Li, Ruijun Sun, Ziqi Wang, Xusheng Yan, Jianxin Jia · 2025 · Journal of Alzheimer s Disease
- NRF2 activation in cancer and overview of NRF2 small molecule inhibitorsHoang Hai Ngo, Bo-Yeong Yu, Jeong‐Eun Lee, Hyun Woo Kim, Young‐Sam Keum · 2025 · Archives of Pharmacal Research
- Systemic activation of NRF2 contributes to the therapeutic efficacy of clinically-approved KRAS-G12C anti-cancer drugsLiam Baird, Lin Zhang, Takanori Hidaka, Lyu Xi, Ke Wang, Keiko Tateno, Tatsuro Iso, Takafumi Suzuki, Kazuki Kumada, Fumiki Katsuoka et al. · 2025 · British Journal of Cancer
- Redox Signaling Modulates Activity of Immune Checkpoint Inhibitors in Cancer PatientsAlessandro Allegra, Giuseppe Murdaca, Giuseppe Mirabile, Sebastiano Gangemi · 2023 · Biomedicines
- Capsaicin acts as a novel NRF2 agonist to suppress ethanol induced gastric mucosa oxidative damage by directly disrupting the KEAP1-NRF2 interactionXiaoning Gao, Wuyan Guo, Peiyuan Liu, Mingyue Yuwen, Hongyu Ren, Shengtao Hu, Zixiang Liu, Ruyang Tan, Kairui Liu, Zhiru Yang et al. · 2026 · eLife
- Glutathione TransferasesBengt Mannervik, Ralf Morgenstern · 2024 · Elsevier eBooks
- The effects of phenolic acid supplementation on intestinal barrier function: a reviewLi Xia, Xiulian Lin, Yuanjiao Zhou, Yamei Li, Yingyan Liao, Yan Lin, Limei Lin, Ping Wu, Jingchen Xie · 2025 · Food & Function
- The role of Nrf2 in autoimmunity and infectious disease: Therapeutic possibilitiesRobert Arthur Freeborn, Cheryl Elizabeth Rockwell · 2021 · Advances in pharmacology
- Patenting perspective on Keap1 inhibitors (2019–2024)Yongfu Luo, Wenlong Yang, Yuan Zhang, Shutong Jiang, Jingyu Zhu, Xiangyang Li, Qidong You, Mengchen Lu · 2025 · Expert Opinion on Therapeutic Patents
- A Comprehensive Review on the Metabolic Cooperation Role of Nuclear Factor E2-Related Factor 2 and Fibroblast Growth Factor 21 against Homeostasis Changes in DiabetesBahar Kiani, Sahar Yarahmadi, Mohsen Nabi‐Afjadi, Hanie Eskandari, Maryam Hasani, Zahra Abbasian, Elham Bahreini · 2022 · Clinical Diabetology
- Sex-based differences in the NRF2 oxidative stress response: Implications for precision therapeuticsGiusy Russomanno, Karolina Kwiatkowska, Ian M. Copple · 2026 · Redox Biology
- The alleviative effect of flavonol‐type Nrf2 activator rhamnazin from Physalis alkekengi L. var. franchetii (Mast.) Makino on pulmonary disordersXueyi Wu, Tian Wang, Hui‐Xin Hu, Kan Zhang, Yu Zhao, Baobing Zhao, Hong‐Xiang Lou, Xiao‐Ning Wang, Tao Shen · 2022 · Phytotherapy Research
- Free Radical Research in CancerAna Čipak Gašparović · 2020 · MDPI eBooks
- Gene network analysis combined with preclinical studies to identify and elucidate the mechanism of action of novel irreversible Keap1 inhibitor for Parkinson’s diseaseMonisha Arumugam, Ranjith Sanjeeve Pachamuthu, Emdormi Rymbai, Aditya Prakash Jha, Kalirajan Rajagopal, Ram Kothandan, Santhoshkumar Muthu, Divakar Selvaraj · 2024 · Molecular Diversity
- The KEAP1-NRF2 system and neurodegenerative diseasesAkira Uruno, Masayuki P. Yamamoto · 2023 · Antioxidants and Redox Signaling
- Cytoprotective Effect of Pteryxin on Insulinoma MIN6 Cells Due to Antioxidant Enzymes Expression via Nrf2/ARE ActivationJunsei Taira, Ryuji Tsuda, Chika Miyagi‐Shiohira, Hirofumi Noguchi, Takayuki Ogi · 2023 · Antioxidants
- Dual targeting of Keap1 and Gsk-3 by hexaraphane in the regulation of transcription factor Nrf2Ángel J. García‐Yagüe, Eduardo Jose Cueto-Diaz, Maribel Escoll, Isao Okunishi, John D. Hayes, Marı́a Isabel Rodrı́guez-Franco, Ana Isabel Rojo, Antonio Cuadrado · 2025 · Free Radical Biology and Medicine
- Therapeutic potential of isothiocyanates by targeting the NRF2 pathwayÁngel J. García‐Yagüe, Eduardo Cazalla, Antonio Cuadrado · 2026 · Free Radical Biology and Medicine
- Long-term 1,2-dimethylhydrazine triggers pathological remodeling of colon mucosa through repression of sestrin2, nuclear factor (erythroid-derived 2)-like 2, and sirtuin4 stimulating mitochondrial stress and metabolic reprogrammingBader-Edine Allal, Abdelkader Bounaama, Dany Silva, Clara Quintas, Salim Ismail Dahlouk, Jorge Gonçalves, Bahia Djerdjouri · 2023 · Naunyn-Schmiedeberg s Archives of Pharmacology
- Heat stress induces oxidative stress and activates the KEAP1‐NFE2L2‐ARE pathway in reproduction‐related cellsHanako Bai, Manabu Kawahara, Kazuya Kusama, Toshihiro Sakurai, Christiane D. Pfarrer, Masashi Takahashi · 2025 · Animal Science Journal
- Effects of fatty acid nitroalkanes on signal transduction pathways and airway macrophage activationMelissa L. Wilkinson, Andrew J. Gow · 2021 · Innate Immunity
- Urinary Thioredoxin as a Biomarker of Renal Redox Dysregulation and a Companion Diagnostic to Identify Responders to Redox-Modulating TherapeuticsKenji Kasuno, Junji Yodoi, Masayuki Iwano · 2021 · Antioxidants and Redox Signaling
- Innate Immune Recognition MoleculesWalter Gottlieb Land · 2018 · Springer eBooks
- Effects of Inhibition of IKK Kinase Phosphorylation On the Cellular Defence System and HSP90 ActivityMiriam Giacomarra, Martina La Torre, Giovanna Montana · 2023 · Inflammation
- Cell-Autonomous (Cell-Intrinsic) Stress ResponsesWalter Gottlieb Land · 2018 · Springer eBooks
- NRF2 and paraquat-induced fatal redox stressJiaojiao Pang, Ying Zhang, Shuyi Wang, Qi Han, Ruru Sun, Changchang Xu, Yue Zheng, Feng Xu, Yuguo Chen, Jun Tao Ren · 2020 · Elsevier eBooks
- AtherosclerosisWalter Gottlieb Land · 2020 · Springer eBooks
- The Chemopreventive Power of IsothiocyanatesSharadha Dayalan Naidu, Lidia Brodziak‐Jarosz, Clarissa Gerhäuser, Albena T. Dinkova‐Kostova · 2020 · Springer eBooks
- KEAP1/NRF2 as a druggable targetAlbena T. Dinkova‐Kostova · 2023 · Arhiv za farmaciju
- Platelet‐Released Growth Factors (PRGFs) Activate NRF2‐ARE and Modulate Inflammatory Response in an NRF2‐Dependent Manner in Primary Human KeratinocytesMatthias Stein, Nicole Böttcher, Mersedeh Tohidnezhad, Athanassios Fragoulis, Andreas U. Bayer, Hannes Klump, Jens Malte Baron, Thomas Pufe · 2025 · Journal of Cosmetic Dermatology
- KMN003 activates Nrf2 via disruption of the Keap1-Nrf2 interaction and p38-dependent transcriptional regulationKeijiro Komeda, Kai Toyoshima, Daisuke Yasuda, Hanako Ishida, Koujin Kojima, Masanori Osawa, Tomoya Hirano, Tomoyuki Ohe, Kenji Tago, Megumi Funakoshi‐Tago · 2025 · Cellular Signalling
- Targeting NRF2 With Isoeugenol: A Promising Small Molecule for Neurodegenerative, Metabolic, and Chronic Inflammatory DisordersAna Silva, Sónia Silva, Beatriz Rodrigues, Gonçalo Simões, Inês Dinis, Mafalda Freitas, Rosa Resende, Joana Bicker, Ana C. Fortuna, Maria M. Silva et al. · 2025 · Oxidative Medicine and Cellular Longevity
- Altered transposon element-derived genes distort oxygen-free radical scavenger systems in FXDTamaki Suganuma, Huzaifa Hassan, Selene Swanson, Sunil Laxman, Jerry L. Workman · 2026 · NAR Molecular Medicine
- Allosecurinine Derivative with Two Michael Acceptors Activates Keap1-Nrf2 PathwaySeoyoung Kim, Rium Kim, Taejin Chu, Jong-Hyun Park, Ki Duk Park, Sunkyu Han · 2026 · Journal of Agricultural and Food Chemistry
- Targeting NRF2 addiction in cancer: synthetic lethal strategies beyond direct inhibitionMelat T. Gebru, David Stokoe · 2026 · Frontiers in Cell and Developmental Biology
- Monoterpene-rich essential oils as natural NRF2 activators: Chemistry, mechanism and antioxidant effectsMelford Chuka Egbujor, Sankhadip Bose · 2026 · Letters in Drug Design & Discovery
- The Cytoprotective Activity of Nrf2 Is Regulated by Phytochemicals (Sulforaphane, Curcumin, and Silymarin)Nancy Vargas-Mendoza, Eli Mireya Sandoval-Gallegos, Eduardo Madrigal‐Santillán, Mauricio Morales-Martínez, Marvin Antonio Soriano-Ursua, Marcelo Ángeles-Valencia, Ángel Morales‐González, Jacqueline Portillo-Reyes, José A. Morales‐González · 2021 · Reference series in phytochemistry
- Nrf2 as a potential target for improving wound healing in the elderlyTetiana R. Dmytriv, Oleh V. Lushchak, Volodymyr I. Lushchak · 2024 · Advances in biogerontology
- Considerations for antibody-based detection of NRF2 in human cellsAlicja Dziadosz, Sara Mikac, Artur Piróg, Zuzanna Urban‐Wójciuk, Monikaben Padariya, Umesh Kalathiya, Sachin Kote, Alicja Sznarkowska · 2025 · Redox Biology
- Basal activation of astrocytic Nrf2 in neuronal culture media: Challenges and implications for neuron-astrocyte modellingMohamed Moftah Omer Elsharkasi, Beatrice Villani, Geoffrey Wells, Fiona Kerr · 2025 · Brain and Neuroscience Advances
- Quantum chemical studies and pharmacophore modeling for designing novel keap1 antagonists that enhance nrf2 mediated neuroprotectionFNU Srinidhi · 2021 · African Journal of Biological Sciences
- Capsaicin acts as a novel NRF2 agonist to suppress ethanol induced gastric mucosa oxidative damage by directly disrupting the KEAP1-NRF2 interactionXiaoning Gao, Wuyan Guo, Peiyuan Liu, Mingyue Yuwen, Hongyu Ren, Shengtao Hu, Zixiang Liu, Ruyang Tan, Kairui Liu, Zhiru Yang et al. · 2024 · eLife
- Capsaicin acts as a novel NRF2 agonist to suppress ethanol induced gastric mucosa oxidative damage by directly disrupting the KEAP1-NRF2 interactionXiaoning Gao, Wuyan Guo, Peiyuan Liu, Mingyue Yuwen, Zixiang Liu, Ruyang Tan, Kairui Liu, Zhiru Yang, Junli Ba, Xue Tao Bai et al. · 2025 · eLife
- The Ancestral KEAP1-NRF Pathway in Amphioxus Branchiostoma japonicum: Implications for the Evolution of Antioxidant Defense SystemWeichen Li, Xiaoqian Liang, Keyu Xiang, Hongyan Li, Yu Zhang · 2025 · International Journal of Molecular Sciences
- Nrf2 contributes to the protective effect of iron overload on thioacetamide-induced chronic liver injury in ratsNanako Hamada, Yuri Ito, Hinata Niimi, Machi Atarashi, Mitsuru Kuwamura, Keiko Taguchi, Masayuki Yamamoto, Takeshi Izawa · 2025 · Toxicological Sciences
- Artemisinin sensitizes triple negative breast cancer to immune checkpoint therapy through suppressing KEAP1-mediated PD-L1 degradationZehua He, Zhaoshuai Chen, Lei Wang, Ziyi Hu, Zhixin Wang, Jiehang Zhou, Yiran Zhu, Zhaorui Lyu, Wencan Zhang, Fan Lin et al. · 2026 · Biochemical Pharmacology
- Methylglyoxal: Hijack-to-survive paradigm of cancer progressionMansi D. Patel, Sudhir Kumar Rawal, Samson Mani · 2026 · Gene Reports
- Dietary Polyphenols as Modulators of Redox Signalling: From the Antioxidant-Pro-Oxidant Continuum to Clinical Translation (2015–2025)José Manuel Pérez de la Lastra, Celia María Curieses Andrés, Elena Bustamante Munguira, Celia Andrés, Eduardo Pérez Lebeña · 2026 · Current Issues in Molecular Biology
- Discovery and Development of Keap1-Nrf2 Protein-Protein Interaction InhibitorsZhengyu Jiang, Qidong You · 2018 · Springer eBooks
- Interactions of Cadmium with Signaling MoleculesDouglas M. Templeton, Ying Liu · 2018 · Springer eBooks
- The Cytoprotective Activity of Nrf2 Is Regulated by Phytochemicals (Sulforaphane, Curcumin, and Silymarin)Nancy Vargas-Mendoza, Eli Mireya Sandoval-Gallegos, Eduardo Madrigal‐Santillán, Mauricio Morales-Martínez, Marvin Antonio Soriano-Ursua, Marcelo Ángeles-Valencia, Ángel Morales‐González, Jacqueline Portillo-Reyes, José A. Morales‐González · 2022 · Reference series in phytochemistry
- The Growing Clinical Relevance of Cellular Stress Responses and Regulated Cell DeathWalter Gottlieb Land · 2020 · Springer eBooks
- Cadmium: Biomolecular InteractionsDouglas M. Templeton · 2023 · Wiley eBooks
- Capsaicin acts as a novel NRF2 agonist to suppress ethanol induced gastric mucosa oxidative damage by directly disrupting the KEAP1-NRF2 interactionXiaoning Gao, Wuyan Guo, Peiyuan Liu, Mingyue Yuwen, Zixiang Liu, Ruyang Tan, Kairui Liu, Zhiru Yang, Junli Ba, Xue Tao Bai et al. · 2024 · eLife
- Genetic Variations in Nrf2-Keap1 Complex: A Step towards Understanding Cancer Resistance in Blind Mole Rats CytotypesDilara Fatma Akın, Teoman Kankılıç · 2019 · Biology Bulletin
- Nrf2 in the Regulation of Endothelial Cell Homeostasis During InflammationHiromi Yamazaki, Ken Itoh · 2020 · Progress in inflammation research
- FAIR and bias-free network modules for mechanism-based disease redefinitionsAhmed Hassan · 2021 · Research Publications (Maastricht University)
- Quantum Chemical Studies and Pharmacophore Modeling for Designing Novel Keap1 Antagonists that Enhance Nrf2 Mediated NeuroprotectionFNU Srinidhi · 2020 · ChemRxiv
- Faculty Opinions recommendation of Keap1, the cysteine-based mammalian intracellular sensor for electrophiles and oxidants.Stuart A. Lipton · 2017 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Quantum Chemical Studies and Pharmacophore Modeling for Designing Novel Keap1 Antagonists that Enhance Nrf2 Mediated NeuroprotectionFNU Srinidhi · 2020 · ChemRxiv
- Role of oxygen on Nuclear factor erythroid-2-like 1 (NFE2L1 or Nrf1) function and stabilityHaiyun Bo · 2019
- Quantum Chemical Studies and Pharmacophore Modeling for Designing Novel Keap1 Antagonists that Enhance Nrf2 Mediated NeuroprotectionFNU Srinidhi · 2020 · ChemRxiv
- Quantum Chemical Studies and Pharmacophore Modeling for Designing Novel Keap1 Antagonists that Enhance Nrf2 Mediated NeuroprotectionFNU Srinidhi · 2020 · ChemRxiv
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- The implications of oxidative stress in long COVID pathogenesisVesna M. Coric · 2023 · Medicinski podmladak
- Chitosan Oligosaccharide Alleviates Diabetic Nephropathy by Strengthening Intestinal Barriers Via Suppressing Myosin Light Chain Kinase and Renal Fibrosis in Type 2 Diabetic RatsPrempree Sutthasupha, Sasivimon Promsan, Nattavadee Pengrattanachot, Nichakorn Phengpol, Chorchat Lalichatsakul, Laongdao Thongnak, Krit Jaikumkao, Rath Pichyangkura, Chatchai Muanprasat, Anusorn Lungkaphin · 2024 · SSRN Electronic Journal
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- Capsaicin acts as a novel NRF2 agonist to suppress ethanol induced gastric mucosa oxidative damage by directly disrupting the KEAP1-NRF2 interactionXiaoning Gao, Wuyan Guo, Peiyuan Liu, Mingyue Yuwen, Hongyu Ren, Shengtao Hu, Zixiang Liu, Ruyang Tan, Kairui Liu, Zhiru Yang et al. · 2026 · eLife
- Compensation for impaired sensing of selenoprotein deficiency by alternative cysteine residues in KEAP1Miu Sato, Takuya Iijima, Takafumi Suzuki, Masayuki P. Yamamoto · 2026 · Redox Biology
- Beyond KEAP1: The Context-Specific NRF2 Partner Code in Disease and TherapySeung-Jin Kwag, Jin‐Kwon Lee, Seung-Jun Lee, Jae-Min Hwang, Young‐Sool Hah · 2026 · Antioxidants
- Overcoming Radiation Resistance: Ferroptosis Induction to Sensitize Solid Tumors to Radiation TherapyJoseph Carmicheal, Caden Fritson, Alexandra A. Seas, Heidi M. Vieira, Surinder K. Batra · 2026 · Cancer Medicine
- TrxR Inhibition and Nrf2–FOXO3 Modulation by Repurposed Drugs: A Redox Strategy to Reverse Cancer Multidrug ResistanceCharan Singh Pawar, Nagarajan Rajendra Prasad · 2026 · Drug Development Research
- Inter-domain distance analysis reveals conformational changes in the Keap1-Nrf2 stress sensor systemRitsumi Saito, Takeshi Kawabata, Seisuke Yamashita, Keisuke Oki, Takashi Fujii, Hiroki Kawauchi, Yoshiaki Doi, Machiko Irie, Takuya Torizawa, Kengo Kinoshita et al. · 2026 · Redox Biology
- Accelerating Cosmetic Innovation Through Next-Generation Computational Toxicology: From Structural Alerts to Molecular Dynamics and Artificial Intelligence for Skin Sensitization AssessmentThomas Enrique Quintero-Trujillo, Liseth DÍAZ-ROJAS, Helen Andrade, Paola Alfonso-Romero · 2026 · Toxics
- Reactive Oxygen Species in Breast Cancer: From Redox Dysregulation to ROS‐Responsive TherapeuticsMarija Nikolovska, Radoslav Stojchevski, Aleksandar Eftimov, Mitko I. Mladenov, Dimiter Bogdanov Avtanski, Nikola Hadzi‐Petrushev · 2026 · Cell Biochemistry and Function
- Cross-species bioanalytical assessment of the oxidative stress and xenobiotic metabolism modes of action for environmental water samples – A multi-layered approach to testing and modellingSebastian Lungu-Mitea, Geeta Mandava, Jana Horackova, Oksana Golovko, Zuzana Toušová, David Bednář, Lutz Ahrens, Klára Hilscherová, Johan Lundqvist · 2026 · Ecotoxicology and Environmental Safety
- Molecular mechanisms of autologous ozonized blood transfusion: Antioxidant and anti-inflammatory effectsLei Chen, Shichao Yang, Yibo Dong, Chunyan Yao · 2026 · Genes & Diseases
- NRF2 signalling in endometriosis: A hormone-independent axis for fertility-preserving therapeutic innovationShen Chen, Yun Lu, Luxuan Wang, Anli Weng, Yuxi Miao, Li Feng, Zhiqi Wang, Mingtao Xu, Xuefang Liang, Yongxia Wang · 2026 · Pharmacological Research
- Dual promoter architecture of NFE2L2 underlies isoform-specific translational control of NRF2A. Sznarkowska, Zuzanna Urban-Wójciuk, Alicja Dziadosz-Brzezińska, Maciej Cieśla, S. Kusiński, Kevork Wakimian, A. Szabelska-Beręsewicz, Elżbieta Chruściel, Ines Papak, Natalia Marek-Trzonkowska et al. · 2026 · Redox Biology
- α,β-Unsaturated carbonyl-based anticancer agents targeting cysteine residuesChuan-Huizi Chen, Nini Zhan, Hongling Xie, Yuke Zhang, Zhengxin Zhou, Xiaojuan Liu, Yangwei Liang, Xianfei Lu, Zhiqing Liu · 2026 · Biochemical Pharmacology
- De Novo Discovery of Cysteine-Targeted Reversible Covalent Cyclic Peptides with Prolonged Residence Time via Phage DisplayYuQian Zhang, Mengzhu Qi, Xiankai Liu, Yukun Zhou, Yanmei Wang, Xing Xiao, Yapei Wu, Wei Gao, Yang Liu, Yiwu Zheng · 2026 · Journal of the American Chemical Society
- Aberrant NRF2-Dependent Cytoprotection Subverts Stress Homeostasis and Promotes Tumor ProgressionGaoqing Feng, Yuhong Yang, H. Wang, Mao Du, Qin Xia, Lei Dong · 2026 · Current Issues in Molecular Biology
- Cysteine-based molecular switches: a focus on KEAP1 and BACH1 in regulating the antioxidant responseJialin Feng, Albena T. Dinkova‐Kostova · 2026 · Archives of Toxicology
- Selective NRF2 target induction despite falling NFE2L2 transcription across the MASLD spectrum: implications for marginal donor grafts and KEAP1-targeted therapySally Campbell, Róisín O’Reilly, Ola Ahmed, Matt McElheron, William C. Chapman, Cliona O’Farrelly · 2026 · Free Radical Biology and Medicine
- BindingDB Entry 50009857: Design, Synthesis, and Initial Evaluation of Affinity-Based Small-Molecule Probes for Fluorescent Visualization and Specific Detection of Keap1.BindingDB · 2021 · UC San Diego
- BindingDB Entry 50020171: Medicinal Chemistry Insights into the Development of Small-Molecule Kelch-Like ECH-Associated Protein 1-Nuclear Factor Erythroid 2-Related Factor 2 (Keap1-Nrf2) Protein-Protein Interaction Inhibitors.BindingDB · 2024 · UC San Diego
- BindingDB Entry 50047995: Discovery and Development of Kelch-like ECH-Associated Protein 1. Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction Inhibitors: Achievements, Challenges, and Future Directions.BindingDB · 2018 · UC San Diego