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Tubulin Acetyltransferase αTAT1 Destabilizes Microtubules Independently of Its Acetylation Activity
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“Likewise, αTAT1 controls microtubule dynamics independent of its tubulin acetylation activity, as a mutant unable to catalyze acetylation still promotes microtubule destabilization [69].”
From Paclitaxel induces NM2 ‐dependent cellular contraction through GEF ‐ H1 dissociation from microtubules and RhoA / ROCK activation in cancer cells (2026) · cites this paper as [69]
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Cites
HDAC6 is a microtubule-associated deacetylase
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HEF1-Dependent Aurora A Activation Induces Disassembly of the Primary Cilium
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In vivo destabilization of dynamic microtubules by HDAC6‐mediated deacetylation
Matsuyama, A., Shimazu, T., Sumida, Y., Saito, A., Yoshimatsu, Y., Seigneurin‐Berny, D., Osada, H., Komatsu, Y., Nishino, N., Khochbin, S., et al. (2002) · The EMBO Journal · doi:10.1093/emboj/cdf682 · Cited by 720
Mice Lacking Histone Deacetylase 6 Have Hyperacetylated Tubulin but Are Viable and Develop Normally
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Cited by
Sorted by citations
Molecular Basis for Age-Dependent Microtubule Acetylation by Tubulin Acetyltransferase
Szyk, A., Deaconescu, A. M., Spector, J., Goodman, B., Valenstein, M. L., Ziolkowska, N. E., Kormendi, V., Grigorieff, N., & Roll-Mecak, A. (2014) · Cell · doi:10.1016/j.cell.2014.03.061 · Cited by 218
Posttranslational Modifications of Tubulin and Cilia
Wloga, D., Joachimiak, E., Louka, P., & Gaertig, J. (2017) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a028159 · Cited by 183
Asensio‐Juárez, G., Pérez‐Díaz, R., Ramos‐Solano, H., Garrido‐Casado, M., Talayero, V. C., & Vicente‐Manzanares, M. (2026) · Molecular Oncology · doi:10.1002/1878-0261.70333
Metadata
- Authors
- Kalebic, N., Martinez, C., Perlas, E., Hublitz, P., Bilbao-Cortes, D., Fiedorczuk, K., Andolfo, A., & Heppenstall, P. A.
- Affiliations
- Mouse Biology Unit, European Molecular Biology Laboratory
- ProMiFa, Protein Microsequencing Facility, San Raffaele Scientific Institute
- Venue
- Molecular and Cellular Biology
- Publisher
- Informa UK Limited
- Published
- 2013-03-01
- Volume
- 33
- Issue
- 6
- Pages
- 1114-1123
- ISSN
- 1098-5549
- Cited by
- 104
- References
- 5
- Language
- en
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- The paper
- Kalebic, N., Martinez, C., Perlas, E., Hublitz, P., Bilbao-Cortes, D., Fiedorczuk, K., Andolfo, A., & Heppenstall, P. A. (2013). Tubulin Acetyltransferase αTAT1 Destabilizes Microtubules Independently of Its Acetylation Activity. Molecular and Cellular Biology. https://doi.org/10.1128/mcb.01044-12