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Cited by 299

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Expression of the mouse dihydrofolate reductase complementary deoxyribonucleic acid in simian virus 40 vectors.

Open access
Subramani, S, Mulligan, R, Berg, P·1981·Molecular and Cellular Biology

Abstract

A mouse complementary deoxyribonucleic acid segment coding for the enzyme dihydrofolate reductase has been cloned in two general classes of vectors containing simian virus 40 deoxyribonucleic acid: (i) those that can be propagated as virions in permissive cells and (ii) those that can be introduced into and maintained stably in various mammalian cells. Both types of vectors express the mouse dihydrofolate reductase by using signals supplied by simian virus 40 deoxyribonucleic acid sequences. Moreover, plasmid vectors carrying the complementary deoxyribonucleic acid segment can complement Chinese hamster ovary cells lacking dihydrofolate reductase.

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Metadata

Authors
Subramani, S., Mulligan, R., & Berg, P.
Venue
Molecular and Cellular Biology
Published
1981-09
Volume
1
Issue
9
Pages
854-864
ISSN
  • 0270-7306 (ISSN-L)
  • 1098-5549
OpenAlex
W1913773160
Cited by
299
References
0
FWCI
11.04
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Expression of the mouse dihydrofolate reductase complementary deoxyribonucleic acid in simian virus 40 vectors. https://app.cochat.ai/papers/10.1128/mcb.1.9.854
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Subramani, S., Mulligan, R., & Berg, P. (1981). Expression of the mouse dihydrofolate reductase complementary deoxyribonucleic acid in simian virus 40 vectors. Molecular and Cellular Biology. https://doi.org/10.1128/mcb.1.9.854

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.