Ras-Mediated Phosphorylation of a Conserved Threonine Residue Enhances the Transactivation Activities of c-Ets1 and c-Ets2
Yang, Beom-Seok, Hauser, Craig A., Henkel, Gregory, Colman, Michael S., Beveren, Charles Van, Stacey, Katryn J., Hume, David A., Maki, Richard A. +1 more·1996·Molecular and Cellular Biology
Cited by (333)
Items 201–300 of 333
- A Central Role for Ets-2 in the Transcriptional Regulation and Cyclic Adenosine 5′-Monophosphate Responsiveness of the Human Chorionic Gonadotropin-β Subunit GeneDebjani Ghosh, Toshihiko Ezashi, Michael C. Ostrowski, R. Michael Roberts · 2003 · Molecular Endocrinology
- Ets-1 Proto-Oncogene as a Potential Predictor for Poor Prognosis of Lung AdenocarcinomaEiichiro Yamaguchi, Toshiyuki Nakayama, Atsushi Nanashima, Keitaro Matsumoto, Toru Yasutake, Ichiro Sekine, Takeshi Nagayasu · 2007 · The Tohoku Journal of Experimental Medicine
- Ets2 and protein kinase Cepsilon are important regulators of parathyroid hormone-related protein expression in MCF-7 breast cancer cellsRalph K. Lindemann, Melanie Braig, Craig A. Hauser, Alfred Nordheim, Jürgen Dittmer · 2003 · Biochemical Journal
- Endothelial Function of von Hippel-Lindau Tumor Suppressor Gene: Control of Fibroblast Growth Factor Receptor SignalingKristen J. Champion, Maria Guinea, Vincent Dammai, Tien Hsu · 2008 · Cancer Research
- ETS Sites in the Promoters of the Matrix Metalloproteinases Collagenase (MMP-1) Stromelysin (MMP-3) are Auxiliary Elements that Regulate Basal and Phorbol-Induced TranscriptionLori Anne White, Christine Maute, Constance Brinckerhoff · 1997 · Connective Tissue Research
- RuvBl2 cooperates with Ets2 to transcriptionally regulate hTERT in colon cancerPadraic Flavin, Aisling M. Redmond, Jean McBryan, Sinéad Cocchiglia, Paul Tibbitts, Patrick Fahy-Browne, Elaine Williamson Kay, Achim Treumann, Kilian Perrem, Marie McIlroy et al. · 2011 · FEBS Letters
- Regulation of Interferon-τ (IFN-τ) Gene Promoters by Growth Factors that Target the Ets-2 Composite Enhancer: A Possible Model for Maternal Control of IFN-τ Production by the Conceptus during Early PregnancyToshihiko Ezashi, R. Michael Roberts · 2004 · Endocrinology
- Parathyroid hormone induces rat interstitial collagenase mRNA through Ets-1 facilitated by cyclic AMP response element-binding protein and Ca(2+)/calmodulin-dependent protein kinase II in osteoblastic cellsCO Quinn, R A Rajakumar, OA Agapova · 2000 · Journal of Molecular Endocrinology
- Ets-1 transcription is required in tissue factor driven microvessel formation and stabilizationGemma Arderiu, Esther Peña, Rosa Aledo, Sonia Espinosa, Lina Badimón · 2012 · Angiogenesis
- Macrophage differentiation of myeloid progenitor cells in response to M-CSF is regulated by the dual-specificity phosphatase DUSP5Marie-France Grasset, Stéphanie Gobert, Guy Mouchiroud, Roland P. Bourette · 2009 · Journal of Leukocyte Biology
- The Pit-1β Domain Dictates Active Repression and Alteration of Histone Acetylation of the Proximal Prolactin PromoterScott E. Diamond, Arthur Gutierrez‐Hartmann · 2000 · Journal of Biological Chemistry
- Transcriptional activity and constitutive nuclear localization of the ETS protein Elf‐1Isa Bredemeier-Ernst, Alfred Nordheim, Ralf Janknecht · 1997 · FEBS Letters
- A global genomic view of MIF knockdown-mediated cell cycle arrestLingfeng Liu, Chaoneng Ji, Jinzhong Chen, Yao Li, Xuping Fu, Yi Xie, Shaohua Gu, Yumin Mao · 2008 · Cell Cycle
- Induction of p38δ Expression Plays an Essential Role in Oncogenic ras-Induced SenescenceJinny Kwong, Michelle S. Chen, Dan Lv, Na Luo, Weijun Su, Rong Xiang, Peiqing Sun · 2013 · Molecular and Cellular Biology
- Stromelysin-1 expression is activated in vivo by Ets-1 through palindromic head-to-head Ets binding sites present in the promoterDavid Baillat, Gabriel Leprivier, Daniel Régnier, Nadejda Vintonenko, Agnès Begue, D. Stéhelin, Marc Aumercier · 2006 · Oncogene
- TEL GENE REARRANGEMENTS IN MYELOID MALIGNANCYTodd R. Golub · 1997 · Hematology/Oncology Clinics of North America
- Oncoprotein Suppression of Tumor Necrosis Factor-induced NFκB Activation Is Independent of Raf-controlled PathwaysJulie Hanson Ostrander, Vasiliki Anest, Julie Y. Reuther-Madrid, Albert S. Baldwin · 2003 · Journal of Biological Chemistry
- Local destabilization, rigid body, and fuzzy docking facilitate the phosphorylation of the transcription factor Ets-1 by the mitogen-activated protein kinase ERK2Andrea Piserchio, Mangalika Warthaka, Tamer Saad Kaoud, Kari Callaway, Kevin N. Dalby, Ranajeet Ghose · 2017 · Proceedings of the National Academy of Sciences
- ETS2 promotes epithelial-to-mesenchymal transition in renal fibrosis by targeting JUNB transcriptionFang Yao, Xiaojing Wang, Zhong‐Kai Cui, Haibing Lan, Xiaolan Ai, Qiancheng Song, Zhenguo Chen, Jun Yang, Bingyi Wu, Xiaochun Bai · 2019 · Laboratory Investigation
- Ets1 is an effector of protein kinase Cα in cancer cellsMartina Vetter, Sibylle G. Blumenthal, Ralph K. Lindemann, Joachim Manns, Sebastian Wesselborg, Christoph Thomssen, Jürgen Dittmer · 2004 · Oncogene
- Ras/MAPK Signaling Modulates VEGFR-3 Expression through Ets-Mediated p300 Recruitment and Histone Acetylation on the Vegfr3 Gene in Lymphatic Endothelial CellsTaeko Ichise, Nobuaki Yoshida, Hirotake Ichise · 2012 · PLoS ONE
- ESE‐3, an Ets family transcription factor, is up‐regulated in cellular senescenceMakoto Fujikawa, Toyomasa Katagiri, Antonio Tugores, Yusuke Nakamura, Fuyuki Ishikawa · 2007 · Cancer Science
- Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2Joshua P. Plotnik, Peter C. Hollenhorst · 2017 · Nucleic Acids Research
- Ets-2 and C/EBP-beta are important mediators of ovine trophoblast Kunitz domain protein-1 gene expression in trophoblast.Anindita Chakrabarty, R. Michael Roberts · 2007 · BMC Molecular Biology
- An Ets motif in the proximal decidual prolactin promoter is essential for basal gene expressionAnoop K. Brar, CA Kessler, Stuart Handwerger · 2002 · Journal of Molecular Endocrinology
- Purification of a Model Substrate for Transcription Factor Phosphorylation by ERK2William F. Waas, Kevin N. Dalby · 2001 · Protein Expression and Purification
- Combinatorial Roles of Protein Kinase A, Ets2, and 3′,5′-Cyclic-Adenosine Monophosphate Response Element-Binding Protein-Binding Protein/p300 in the Transcriptional Control of Interferon-τ Expression in a Trophoblast Cell LinePadmalaya Das, Toshihiko Ezashi, Rangan Gupta, R. Michael Roberts · 2007 · Molecular Endocrinology
- Transcription Factor ets-2 Plays an Important Role in the Pathogenesis of Pulmonary FibrosisChristopher P. Baran, Sara N. Fischer, Gerard James Nuovo, Mohamed Kabbout, Charles L. Hitchcock, Benjamin D. Bringardner, Sara McMaken, Christie A. Newland, Carmen Z. Cantemir-Stone, Gary S. Phillips et al. · 2011 · American Journal of Respiratory Cell and Molecular Biology
- Okadaic acid stimulates osteopontin expression through de novo induction of AP‐1Hyun‐Jung Kim, Mi‐Hye Lee, Hyun‐Jung Kim, Hong‐In Shin, Je‐Yong Choi, Hyun‐Mo Ryoo · 2002 · Journal of Cellular Biochemistry
- MicroRNA 17-92 Cluster Mediates ETS1 and ETS2-Dependent RAS-Oncogenic TransformationMohamed Kabbout, Duaa A. Dakhlallah, Sudarshana M. Sharma, Agnieszka Bronisz, Ruchika Srinivasan, Melissa G. Piper, Clay B. Marsh, Michael C. Ostrowski · 2014 · PLoS ONE
- Epiregulin expression by Ets-1 and ERK signaling pathway in Ki-ras-transformed cellsMin-Chul Cho, Hee-Sook Choi, Sojung Lee, Bo Yeon Kim, Mira Jung, Sue Nie Park, Do‐Young Yoon · 2008 · Biochemical and Biophysical Research Communications
- Ets transcription factors regulate AIRE gene promoterAstrid Murumägi, Olli Silvennoinen, Pärt Peterson · 2006 · Biochemical and Biophysical Research Communications
- Butyrate and propionate downregulate ERK phosphorylation in HT-29 colon carcinoma cells prior to differentiationDavid J. Davido, Frank Richter, Frank Boxberger, A Stahl, Thomas Menzel, H Lührs, Silke Löffler, Gerda Dusel, U R Rapp, Wolfgang M. Scheppach · 2001 · European Journal of Cancer Prevention
- Transcription Factor Ets1 Regulates Expression of Thioredoxin-Interacting Protein and Inhibits Insulin Secretion in Pancreatic β-CellsYan Luo, Fengli He, Li Hu, Luo Hai, Meifeng Huang, Zhipeng Xu, Jingjing Zhang, Zhiguang Zhou, Feng Liu, Yan‐Shan Dai · 2014 · PLoS ONE
- The transcription factor ETS-1 regulates angiotensin II-stimulated fibronectin production in mesangial cellsPing Hua, Wenguang Feng, Gabriel Rezonzew, Phillip H. Chumley, Edgar A. Jaimes · 2012 · American Journal of Physiology-Renal Physiology
- Id1 Is Down-Regulated by Hepatocyte Growth Factor via ERK-Dependent and ERK-Independent Signaling Pathways, Leading to Increased Expression of p16INK4a in Hepatoma CellsKazutaka Ushio, Tomio Hashimoto, Naomi Kitamura, Toshiaki Tanaka · 2009 · Molecular Cancer Research
- Ets1 Transcription Factor Mediates Gastrin-Releasing Peptide-Induced IL-8 Regulation in Neuroblastoma CellsJingbo Qiao, Jung-Hee Kang, Jeremy Cree, Bernard Mark Evers, Dai H. Chung · 2007 · Neoplasia
- Regulation of urokinase plasminogen activator gene transcription in the RAW264 murine macrophage cell line by macrophage colony-stimulating factor (CSF-1) is dependent upon the level of cell-surface receptorLindsay Fowles, Katryn J. Stacey, Denese C. Marks, John A. HAMILTON, David Arthur Hume · 2000 · Biochemical Journal
- The Small GTPases Ras, Rac, and Cdc42 Transcriptionally Regulate Expression of Human Fibroblast Growth Factor 1Maqsood Ahmed Chotani, Kathy Touhalisky, Ing‐Ming Chiu · 2000 · Journal of Biological Chemistry
- Role of Ets2 in cyclic AMP regulation of the human chorionic gonadotropin β promoterW Johnson · 2000 · Molecular and Cellular Endocrinology
- Inhibitory effects of the transcription factor Ets-1 on the expression of type I collagen in TGF-β1-stimulated renal epithelial cellsKazuhiro Okano, Asako Hibi, Tokiko Miyaoka, Tomoko Inoue, Himiko Sugimoto, Ken Tsuchiya, Takashi Akiba, Kosaku Nitta · 2012 · Molecular and Cellular Biochemistry
- Lessons from Drosophila Pointed, an ETS family transcription factor and key nuclear effector of the RTK signaling pathwayPavithra Vivekanand · 2018 · genesis
- Coordinate Regulation of Basal and Cyclic 5′-Adenosine Monophosphate (cAMP)-Activated Expression of Human Chorionic Gonadotropin-α by Ets-2 and cAMP-Responsive Element Binding ProteinDebjani Ghosh, Shrikesh Sachdev, Mark Hannink, R. Michael Roberts · 2005 · Molecular Endocrinology
- The Relationship Between CSF1R Signaling, Monocyte-Macrophage Differentiation, and Susceptibility to Inflammatory Bowel DiseaseDavid Arthur Hume, KIM M. SUMMERS, Claire Louise O'Brien, Paul Pavli · 2025 · Cellular and Molecular Gastroenterology and Hepatology
- Inhibition of PLC-γ1 activity converts nerve growth factor from an anti-mitogenic to a mitogenic signal in CHO cellsAntje Zapf-Colby, Jens Eichhorn, Nicholas J. G. Webster, Jerrold M. Olefsky · 1999 · Oncogene
- Vitamin D Signaling Modulators in Cancer TherapyWei Luo, Candace S. Johnson, Donald L. Trump · 2016 · Vitamins and hormones
- Transcriptional Regulation of c-fms Gene ExpressionYue Xie, Changmin Chen, David Arthur Hume · 2001 · Cell Biochemistry and Biophysics
- c-Jun and Ets2 Proteins Regulate Expression of Spleen Tyrosine Kinase in T CellsDebjani Ghosh, George C. Tsokos, Vasileios C. Kyttaris · 2012 · Journal of Biological Chemistry
- Role of Ets‐1 phosphorylation in the effector function of Th cellsRoland Grenningloh, Shi‐Chuen Miaw, Jacques Moisan, Barbara J. Graves, I‐Cheng Ho · 2008 · European Journal of Immunology
- Ets-1 Regulates Radial Glia Formation During Vertebrate EmbryogenesisTomomi Kiyota, Akiko Kato, Yoichi Kato · 2007 · Organogenesis
- Essential Role of the Transcription Factor Ets-2 inXenopus Early DevelopmentKaoru Kawachi, Norihisa Masuyama, Eisuke Nishida · 2003 · Journal of Biological Chemistry
- Identification of Ets-1 as an Important Transcriptional Activator of CTP: Phosphocholine Cytidylyltransferase α in COS-7 Cells and Co-activation with Transcriptional Enhancer Factor-4Hiroyuki Sugimoto, Sayaka Sugimoto, Kazuaki Tatei, Hideru Obinata, Marica Bakovic, Takashi Izumi, Dennis E. Vance · 2003 · Journal of Biological Chemistry
- Regulation of CEACAM1 Protein Expression by the Transcription Factor ETS-1 in BRAF-Mutant Human Metastatic Melanoma CellsKarin Kfir-Elirachman, Rona Ortenberg, Bella Vizel, Michal Judith Besser, Iris Barshack, Jacob Schachter, Yael Nemlich, Gal Markel · 2018 · Neoplasia
- Transcriptional coordination of the genes encoding catalytic (CK2α) and regulatory (CK2β) subunits of human protein kinase CK2Walter G. Pyerin, Karin Ackermann · 2001 · Molecular and Cellular Biochemistry
- Inducible expression of the megakaryocyte-specific gene glycoprotein IX is mediated through an Ets binding site and involves upstream activation of extracellular signal-regulated kinase.Michael Eisbacher, Levon Michael Khachigian, Thet Hta Khin, Melissa L. Holmes, Beng H. Chong · 2001 · PubMed
- Polyomavirus Middle T Antigen Induces the Transcription of Osteopontin, a Gene Important for the Migration of Transformed CellsKerry A. Whalen, Georg F. Weber, Thomas L. Benjamin, Brian S. Schaffhausen · 2008 · Journal of Virology
- A genetic variation in microRNA target site of ETS2 is associated with clinical outcomes of paclitaxel-cisplatin chemotherapy in non-small cell lung cancerMi Jeong Hong, Shin Yup Lee, Jin Eun Choi, Cheng Jin, Hyo Jung Kang, Sun Ah Baek, So Yeon Lee, Kyung Min Shin, Ji Yun Jeong, Won Kee Lee et al. · 2016 · Oncotarget
- Cellular stress triggers TEL nuclear export via two genetically separable pathwaysCaroline A. Hanson, Lauren D. Wood, Scott W. Hiebert · 2007 · Journal of Cellular Biochemistry
- The Long Terminal Repeats of Human Immunodeficiency Virus Type-1 and Human T-cell Leukemia Virus Type-I Are Activated by 12-O-Tetradecanoylphorbol- 13-acetate through Different PathwaysNirit Mor‐Vaknin, Amram Torgeman, Dalia Galron, Martin Löchelt, Rolf M. Flügel, Mordechai Aboud · 1997 · Virology
- Transcription Factor ETS-1 and Reactive Oxygen Species: Role in Vascular and Renal InjuryYan-Ting Elizabeth Shiu, Edgar A. Jaimes · 2018 · Antioxidants
- EBV-Encoded LMP1 Upregulates Igκ 3′Enhancer Activity and Igκ Expression in Nasopharyngeal Cancer Cells by Activating the Ets-1 through ERKs SignalingHaidan Liu, Zhi Duan, Hui Zheng, Duosha Hu, Ming Li, Yongguang Tao, Ann M. Bode, Zigang Dong, Ya Cao · 2012 · PLoS ONE
- Suppressive effect of SATB1 on hepatic stellate cell activation and liver fibrosis in ratsJiayi He, Jin Gong, Qiang Ding, Qinghai Tan, Ping Han, Jingmei Liu, Zhenzhen Zhou, Wei Tu, Yujia Xia, Wei Yan et al. · 2015 · FEBS Letters
- Gene targeting approach to selectively kill colon cancer cells, with hyperactive K-Ras pathwayHadas Dvory‐Sobol, Dina Kazanov, Nadir Arber · 2005 · Biomedicine & Pharmacotherapy
- Antigen-induced Erk1/2 activation regulates Ets-1-mediated sensitization of CD8+ T cells for IL-12 responsesQingsheng Li, Cheryl Eppolito, Kunle O. Odunsi, Protul A. Shrikant · 2009 · Journal of Leukocyte Biology
- Cloning and characterization of GETS-1, a goldfish Ets family member that functions as a transcriptional repressor in muscleDaniel J. Goldman, Mohan K. Sapru, Scott STEWART, Joshua B. Plotkin, Towia A. Libermann, Bohdan Wasylyk, Kun‐Liang Guan · 1998 · Biochemical Journal
- Ets1 is a common element in directing transcription of the α and β genes of human protein kinase CK2Andreas Krehan, Rüdiger Schmalzbauer, Oliver Böcher, Karin Ackermann, Ute Wirkner, Stefan Brouwers, Walter G. Pyerin · 2001 · European Journal of Biochemistry
- The interaction between ETS transcription factor family members and microRNAs: A novel approach to cancer therapyLiwei Du, Yuchen Liu, Chenxi Li, Jinkuang Deng, Yi Sang · 2022 · Biomedicine & Pharmacotherapy
- Transcriptional Regulation of Siglec-15 by ETS-1 and ETS-2 in Hepatocellular Carcinoma CellsKaiqin Sheng, Yuecheng Wu, Hanbin Lin, Menghan Fang, Chaorong Xue, Lin Xu, Xinjian Lin · 2023 · International Journal of Molecular Sciences
- Importance of local interactions for the stability of inhibitory helix 1 in apo Ets-1Aleksandra M. Karolak, Arjan van der Vaart · 2012 · Biophysical Chemistry
- Differential Utilization of Transcription Activation Subdomains by Distinct Coactivators Regulates Pit-1 Basal and Ras ResponsivenessDawn L. Duval, Matthew D. Jonsen, Scott E. Diamond, Patience Murapa, Annie Jean, Arthur Gutierrez‐Hartmann · 2006 · Molecular Endocrinology
- Ets Transcription FactorsAndrew P. Bradford, Arthur Gutierrez‐Hartmann · 2000 · Humana Press eBooks
- Transcriptional coordination of the genes encoding catalytic (CK2α) and regulatory (CK2β) subunits of human protein kinase CK2Walter G. Pyerin, Karin Ackermann · 2001 · Springer eBooks
- Avian erythroblastosis virus E26 oncogene homolog-1 (ETS-1) plays a role in renal microvascular pathophysiology in the Dahl salt-sensitive ratWenguang Feng, Zhengrong Guan, Dongqi Xing, Xingsheng Li, Wei‐Zhong Ying, Colton E. Remedies, Edward W. Inscho, Paul W. Sanders · 2019 · Kidney International
- Ets2 is not required for Ras or Neu/ErbB-2 mediated cellular transformation in vitroAnikó Hevér, Robert G. Oshima, Craig A. Hauser · 2003 · Experimental Cell Research
- Modulation of p53 N-terminal transactivation domain 2 conformation ensemble and kinetics by phosphorylationLikun Zhao, Y. Ouyang, Qian Li, Zhu-Qing Zhang · 2020 · Journal of Biomolecular Structure and Dynamics
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- Experimental and integrative analyses identify an ETS1 network downstream of BCR-ABL in chronic myeloid leukemia (CML)Christophe Desterke, Maud Voldoire, Marie‐Laure Bonnet, Nathalie Sorel, Sarah Pagliaro, Hind Rahban, Annelise Bennaceur Griscelli, Émilie Cayssials, Jean‐Claude Chomel, Ali G. Turhan · 2018 · Experimental Hematology
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- Model of neural induction in the ascidian embryoRossana Bettoni, C. Hudson, Géraldine Williaume, Cathy Sirour, H. Yasuo, S. de-Buyl, G. Dupont · 2022 · bioRxiv
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- The Role of Ets Transcription Factors in Mediating Cellular TransformationG. Foos, Craig A. Hauser · 2004 · Handbook of experimental pharmacology
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