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The Repertoire of Fos and Jun Proteins Expressed during the G1 Phase of the Cell Cycle Is Determined by the Duration of Mitogen-Activated Protein Kinase Activation

Cook, S. J., Aziz, N. A., & McMahon, M. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.1.330 · Cited by 180 · see citing works

CCL2 Regulates Angiogenesis via Activation of Ets-1 Transcription Factor

Stamatovic, S. M., Keep, R. F., Mostarica‐Stojković, M., & Andjelkovic, A. V. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.4.2651 · Cited by 177 · see citing works

Post-translational modifications influence transcription factor activity: A view from the ETS superfamily

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Erk Kinases Link Pre-B Cell Receptor Signaling to Transcriptional Events Required for Early B Cell Expansion

Yasuda, T., Sanjo, H., Pagès, G., Kawano, Y., Karasuyama, H., Pouysségur, J., Ogata, M., & Kurosaki, T. (2008) · Immunity · doi:10.1016/j.immuni.2008.02.015 · Cited by 170 · see citing works

Transcription Factors in Cancer Development and Therapy

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The molecular regulation of arteriovenous specification and maintenance

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Grb2 and Shc Adapter Proteins Play Distinct Roles in Neu (ErbB-2)-Induced Mammary Tumorigenesis: Implications for Human Breast Cancer

Dankort, D. L., Maślikowski, B. M., Warner, N. E., Kanno, N., Kim, H. L., Wang, Z., Moran, M. F., Oshima, R. G., Cardiff, R. D., & Muller, W. J. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.5.1540-1551.2001 · Cited by 163 · see citing works

Rapid Phosphorylation of Ets-2 Accompanies Mitogen-Activated Protein Kinase Activation and the Induction of Heparin-Binding Epidermal Growth Factor Gene Expression by Oncogenic Raf-1

McCarthy, S. A., Chen, D. W., Yang, B.-S., Garcı́a-Ramı́rez, J. J., Cherwinski, H. M., Chen, X., Klagsbrun, M., Hauser, C. A., Ostrowski, M. C., & McMahon, M. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.5.2401 · Cited by 163 · see citing works

Hepatocyte growth factor/scatter factor activates the ETS1 transcription factor by a RAS-RAF-MEK-ERK signaling pathway

Paumelle, R., Tulasne, D., Kherrouche, Z., Plaza, S., Leroy, C., Reveneau, S., Vandenbunder, B., & Fafeur, V. (2002) · Oncogene · doi:10.1038/sj.onc.1205297 · Cited by 158 · see citing works

The adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memory

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Elf5 is essential for early embryogenesis and mammary gland development during pregnancy and lactation

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Oncogenic regulation and function of keratins 8 and 18

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Granulocyte inducer C/EBPα inactivates the myeloid master regulator PU.1: possible role in lineage commitment decisions

Reddy, V. A., Iwama, A., Iotzova, G., Schulz, M., Elsasser, A., Vangala, R. K., Tenen, D. G., Hiddemann, W., & Behre, G. (2002) · Blood · doi:10.1182/blood.v100.2.483 · Cited by 152 · see citing works

Phosphorylation represses Ets-1 DNA binding by reinforcing autoinhibition

Cowley, D. O., & Graves, B. J. (2000) · Genes &amp; Development · doi:10.1101/gad.14.3.366 · Cited by 152 · see citing works

The Ets family contains transcriptional activators and repressors involved in angiogenesis

Lelièvre, E. (2001) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/s1357-2725(01)00025-5 · Cited by 150 · see citing works

Control of Lytic Function by Mitogen-activated Protein Kinase/Extracellular Regulatory Kinase 2 (ERK2) in a Human Natural Killer Cell Line: Identification of Perforin and Granzyme B Mobilization by Functional ERK2

Wei, S., Gamero, A. M., Liu, J. H., Daulton, A. A., Valkov, N. I., Trapani, J. A., Larner, A. C., Weber, M. J., & Djeu, J. Y. (1998) · The Journal of Experimental Medicine · doi:10.1084/jem.187.11.1753 · Cited by 149 · see citing works

Ets2 Maintains hTERT Gene Expression and Breast Cancer Cell Proliferation by Interacting with c-Myc

Xu, D., Dwyer, J., He, L., Duan, W., & Liu, J. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m800790200 · Cited by 141 · see citing works

Molecular mechanisms of ETS transcription factor-mediated tumorigenesis

Kar, A., & Gutierrez‐Hartmann, A. (2013) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.3109/10409238.2013.838202 · Cited by 144 · see citing works

p300/cAMP-responsive Element-binding Protein Interactions with Ets-1 and Ets-2 in the Transcriptional Activation of the Human Stromelysin Promoter

Jayaraman, G., Srinivas, R., Duggan, C. R., Ferreira, E., Swaminathan, S., Somasundaram, K., Williams, J. T., Hauser, C. A., Kurkinen, M. T., Dhar, R., et al. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.24.17342 · Cited by 137 · see citing works

Structure of the Ets-1 pointed domain and mitogen-activated protein kinase phosphorylation site

Slupsky, C. M., Gentile, L. N., Donaldson, L. W., Mackereth, C. D., Seidel, J. J., Graves, B. J., & McIntosh, L. P. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.21.12129 · Cited by 139 · see citing works

Ets transcription factors and human disease

Dittmer, J., & Nordheim, A. (1998) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/s0304-419x(97)00039-5 · Cited by 136 · see citing works

Foxs and Ets in the transcriptional regulation of endothelial cell differentiation and angiogenesis

Dejana, E., Taddei, A., & RANDI, A. M. (2007) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2007.05.003 · Cited by 131 · see citing works

Induction of β3-Integrin Gene Expression by Sustained Activation of the Ras-Regulated Raf–MEK–Extracellular Signal-Regulated Kinase Signaling Pathway

Woods, D. B., Cherwinski, H. M., Venetsanakos, E., Bhat, A., Gysin, S., Humbert, M., Bray, P. F., Saylor, V., & McMahon, M. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.9.3192-3205.2001 · Cited by 131 · see citing works

Phenotypic impacts of CSF1R deficiencies in humans and model organisms

Hume, D. A., Caruso, M., Ferrari-Cestari, M., SUMMERS, K. M., Pridans, C., & Irvine, K. M. (2019) · Journal of Leukocyte Biology · doi:10.1002/jlb.mr0519-143r · Cited by 121 · see citing works

IFITM1 plays an essential role in the antiproliferative action of interferon-γ

Yang, G., Xu, Y., Chen, X., & Hu, G. (2006) · Oncogene · doi:10.1038/sj.onc.1209807 · Cited by 129 · see citing works

Upregulation of the Catalytic Telomerase Subunit by the Transcription Factor ER81 and Oncogenic HER2/Neu, Ras, or Raf

Goueli, B. S., & Janknecht, R. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.24.1.25-35.2004 · Cited by 129 · see citing works

Oncogenic Neu/ErbB-2 Increases Ets, AP-1, and NF-kB-dependent Gene Expression, and Inhibiting Ets Activation Blocks Neu-mediated Cellular Transformation

Galang, C. K., Garcı́a-Ramı́rez, J. J., Solski, P. A., Westwick, J. K., Der, C. J., Neznanov, N. S., Oshima, R. G., & Hauser, C. A. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.14.7992 · Cited by 127 · see citing works

Associations and Interactions between Ets-1 and Ets-2 and Coregulatory Proteins, SRC-1, AIB1, and NCoR in Breast Cancer

Myers, E., Hill, A. D. K., Kelly, G., McDermott, E. W. M., O’Higgins, N. J., Buggy, Y., & Young, L. S. (2005) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-04-1192 · Cited by 123 · see citing works

Genetic and Physical Interactions betweenMicrophthalmia Transcription Factor and PU.1 Are Necessary for Osteoclast Gene Expression and Differentiation

Luchin, A. I., Suchting, S., Merson, T. D., Rosol, T. J., Hume, D. A., Cassady, A. I., & Ostrowski, M. C. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m106418200 · Cited by 123 · see citing works

ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells

Plotnik, J. P., Budka, J. A., Ferris, M. W., & Hollenhorst, P. C. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku929 · Cited by 120 · see citing works

Ets-1 deficiency leads to altered B cell differentiation, hyperresponsiveness to TLR9 and autoimmune disease

Wang, D., John, S. A., Clements, J. L., Percy, D. H., Barton, K., & Garrett‐Sinha, L. A. (2005) · International Immunology · doi:10.1093/intimm/dxh295 · Cited by 119 · see citing works

Cdk10, a Cdc2-related kinase, associates with the Ets2 transcription factor and modulates its transactivation activity

Kasten, M. M., & Giordano, A. (2001) · Oncogene · doi:10.1038/sj.onc.1204295 · Cited by 117 · see citing works

The Sos1 and Sos2 Ras‐specific exchange factors: differences in placental expression and signaling properties

Qian, X., Esteban, L., Vass, W. C., Upadhyaya, C. D., Papageorge, A. G., Yienger, K., Ward, J. M., Lowy, D. R., & Santos, E. (2000) · The EMBO Journal · doi:10.1093/emboj/19.4.642 · Cited by 116 · see citing works

Ets1 Is an Effector of the Transforming Growth Factor β (TGF-β) Signaling Pathway and an Antagonist of the Profibrotic Effects of TGF-β

Czuwara-Ladykowska, J., Sementchenko, V. I., Watson, D. K., & Trojanowska, M. E. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m200206200 · Cited by 116 · see citing works

Ets-1 is an early response gene activated by ET-1 and PDGF-BB in vascular smooth muscle cells

Naito, S., Shimizu, S., Maeda, S., Wang, J., Paul, R. J., & Fagin, J. A. (1998) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1998.274.2.c472 · Cited by 115 · see citing works

The function of APC/CCdh1 in cell cycle and beyond

Li, M., & Zhang, P. (2009) · Cell Division · doi:10.1186/1747-1028-4-2 · Cited by 112 · see citing works

ERK phosphorylation is linked to VEGFR2 expression and Ets-2 phosphorylation in breast cancer and is associated with tamoxifen treatment resistance and small tumours with good prognosis

Svensson, S., Jirström, K., Rydén, L., Roos, G., Emdin, S. O., Ostrowski, M. C., & Landberg, G. (2005) · Oncogene · doi:10.1038/sj.onc.1208626 · Cited by 113 · see citing works

The Role of Ets Transcription Factors in the Development and Function of the Mammalian Immune System

Bassuk, A. G., & Leiden, J. M. (1997) · Advances in immunology · doi:10.1016/s0065-2776(08)60887-1 · Cited by 110 · see citing works

LIV-1 Promotes Prostate Cancer Epithelial-to-Mesenchymal Transition and Metastasis through HB-EGF Shedding and EGFR-Mediated ERK Signaling

Lue, H.-W., Yang, X., Wang, R., Qian, W., Xu, R. Z. H., Lyles, R. H., Osunkoya, A. O., Zhou, B. P., Vessella, R. L., Zayzafoon, M., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0027720 · Cited by 111 · see citing works

HER2/Neu-mediated activation of the ETS transcription factor ER81 and its target gene MMP-1

Bosc, D. G., Goueli, B. S., & Janknecht, R. (2001) · Oncogene · doi:10.1038/sj.onc.1204820 · Cited by 108 · see citing works

Interaction of Ets-1 and the POU-Homeodomain Protein GHF-1/Pit-1 Reconstitutes Pituitary-Specific Gene Expression

Bradford, A. P., Wasylyk, C., Wasylyk, B., & Gutierrez‐Hartmann, A. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.3.1065 · Cited by 107 · see citing works

MRG1 Binds to the LIM Domain of Lhx2 and May Function as a Coactivator to Stimulate Glycoprotein Hormone α-Subunit Gene Expression

Glenn, D. J., & Maurer, R. A. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.51.36159 · Cited by 106 · see citing works

Regulation of the Human Interleukin-5 Promoter by Ets Transcription Factors

Blumenthal, S. G., Aichele, G., Wirth, T. C., Czernilofsky, A. P., Nordheim, A., & Dittmer, J. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.18.12910 · Cited by 107 · see citing works

TEL, a Putative Tumor Suppressor, Modulates Cell Growth and Cell Morphology of Ras-Transformed Cells While Repressing the Transcription of stromelysin-1

Fenrick, R., Wang, L., Nip, J., Amann, J. M., Rooney, R. J., Walker‐Daniels, J., Crawford, H. C., Hulboy, D. L., Kinch, M. S., Matrisian, L. M., et al. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.16.5828-5839.2000 · Cited by 106 · see citing works

Role of MAP Kinases in the 1,25-Dihydroxyvitamin D3-induced Transactivation of the Rat Cytochrome P450C24 (CYP24) Promoter

Dwivedi, P. P., Hii, C. S. T., Ferrante, A., Tan, J., Der, C. J., Omdahl, J. L., Morris, H. A., & May, B. K. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m204561200 · Cited by 106 · see citing works

Transcriptional Repressor ERF Is a Ras/Mitogen-Activated Protein Kinase Target That Regulates Cellular Proliferation

Gallic, L. L., Sgouras, D. N., Beal, G., & Mavrothalassitis, G. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.6.4121 · Cited by 106 · see citing works

EGFR inhibition evokes innate drug resistance in lung cancer cells by preventing Akt activity and thus inactivating Ets-1 function

Phuchareon, J., McCormick, F. P., Eisele, D. W., & Tetsu, O. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1510733112 · Cited by 105 · see citing works

Persistent Activation of Mitogen-Activated Protein Kinases p42 and p44 and ets-2 Phosphorylation in Response to Colony-Stimulating Factor 1/c-fms Signaling

Fowles, L., Martin, M. L., Nelsen, L., Stacey, K. J., Redd, D., Clark, Y. M., Nagamine, Y., McMahon, M., Hume, D. A., & Ostrowski, M. C. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.9.5148 · Cited by 104 · see citing works

Fli1 and Ets1 Have Distinct Roles in Connective Tissue Growth Factor/CCN2 Gene Regulation and Induction of the Profibrotic Gene Program

Nakerakanti, S. S., Kapanadze, B., Yamasaki, M., Markiewicz, M., & Trojanowska, M. E. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m600466200 · Cited by 103 · see citing works

Transcription factor Ets-1 in cytokine and chemokine gene regulation

Russell, L., & Garrett‐Sinha, L. A. (2010) · Cytokine · doi:10.1016/j.cyto.2010.03.006 · Cited by 102 · see citing works

Phosphorylation of the Transactivation Domain of Pax6 by Extracellular Signal-regulated Kinase and p38 Mitogen-activated Protein Kinase

Mikkola, I., Bruun, J., Bjørkøy, G., Holm, T., & Johansen, T. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.21.15115 · Cited by 102 · see citing works

Maintenance of Vascular Integrity in the Embryo Requires Signaling through the Fibroblast Growth Factor Receptor

Lee, S. H., Schloss, D. J., & Swain, J. L. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m004994200 · Cited by 101 · see citing works

Triplex DNA-mediated downregulation of Ets2 expression results in growth inhibition and apoptosis in human prostate cancer cells

Carbone, G. M. (2004) · Nucleic Acids Research · doi:10.1093/nar/gkh744 · Cited by 100 · see citing works

Epidermal Growth Factor Receptor Signaling Activates Met in Human Anaplastic Thyroid Carcinoma Cells

Bergström, J. D., Westermark, B., & Heldin, N. (2000) · Experimental Cell Research · doi:10.1006/excr.2000.4967 · Cited by 98 · see citing works

Repression of Ets-2-Induced Transactivation of the Tau Interferon Promoter by Oct-4

Ezashi, T., Ghosh, D., & Roberts, R. M. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.23.7883-7891.2001 · Cited by 98 · see citing works

Transforming Growth Factor β Regulates Parathyroid Hormone-related Protein Expression in MDA-MB-231 Breast Cancer Cells through a Novel Smad/Ets Synergism

Lindemann, R. K., Ballschmieter, P., Nordheim, A., & Dittmer, J. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m105816200 · Cited by 95 · see citing works

ERK1/2 Regulates Intracellular ATP Levels through α-Enolase Expression in Cardiomyocytes Exposed to Ischemic Hypoxia and Reoxygenation

Mizukami, Y., Iwamatsu, A., Aki, T., Kimura, M., Nakamura, K., Nao, T., Okusa, T., Matsuzaki, M., Yoshida, K., & Kobayashi, S. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m402299200 · Cited by 96 · see citing works

Regulation of endothelial cell development by ETS transcription factors

Meadows, S. M., Myers, C. T., & Krieg, P. A. (2011) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2011.09.009 · Cited by 93 · see citing works

The Ets-1 transcription factor is required for complete pre-T cell receptor function and allelic exclusion at the T cell receptor β locus

Eyquem, S., Chemin, K., Fasseu, M., & Bories, J.-C. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0405546101 · Cited by 94 · see citing works

Expression of the Ets-1 transcription factor in human astrocytomas is associated with Fms-like tyrosine kinase-1 (Flt-1)/vascular endothelial growth factor receptor-1 synthesis and neoangiogenesis.

Valter, M. M., Hügel, A., Huang, H. J., Cavenee, W. K., Wiestler, O. D., Pietsch, T., & Wernert, N. (1999) · PubMed · Cited by 94 · see citing works

The Raf signal transduction cascade as a target for chemotherapeutic intervention in growth factor-responsive tumors

Oppenheimer, C. W., Blalock, W. L., Steelman, L. S., Chang, F., & McCubrey, J. A. (2000) · Pharmacology & Therapeutics · doi:10.1016/s0163-7258(00)00085-1 · Cited by 93 · see citing works

Ets-1 is a transcriptional mediator of oncogenic nitric oxide signaling in estrogen receptor-negative breast cancer

Switzer, C. H., Cheng, R. Y.-S., Ridnour, L. A., Glynn, S. A., Ambs, S., & Wink, D. A. (2012) · Breast Cancer Research · doi:10.1186/bcr3319 · Cited by 91 · see citing works

Regulation of Rat Cytochrome P450C24 (CYP24) Gene Expression

Dwivedi, P. P., Omdahl, J. L., Kola, I., Hume, D. A., & May, B. K. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.1.47 · Cited by 90 · see citing works

These include:

Biol, M. C., Stacey, J., Hume, D. A., Maki, R. A., Ostrowski, M. C., Yang, B. S., Ca, H., Henkel, G., Colman, M. S., Beveren, C. V., et al. (1995)

Conserved mechanisms of Ras regulation of evolutionary related transcription factors, Ets1 and Pointed P2

Wasylyk, C., Bradford, A. P., Gutierrez-Hartmann, A., & Wasylyk, B. (1997) · Oncogene · doi:10.1038/sj.onc.1200914 · Cited by 101 · see citing works

Oncogenic Ras can induce transcriptional activation through a variety of promoter elements, including tandem c-Ets-2 binding sites.

Galang, C. K., Der, C. J., & Hauser, C. A. (1994) · PubMed · Cited by 120 · see citing works

Phosphorylation Regulates the Transcriptional Response of the Ets-2 "Pointed" Domain

Schaffner, A. E. (2000) · OhioLink ETD Center (Ohio Library and Information Network)

Elevated Expression of Ets2 or Distinct Portions of Ets2 Can Reverse Ras-mediated Cellular Transformation

Foos, G. E., Garcı́a-Ramı́rez, J. J., Galang, C. K., & Hauser, C. A. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.30.18871 · Cited by 51 · see citing works