Shp-2 Tyrosine Phosphatase Functions as a Negative Regulator of the Interferon-Stimulated Jak/STAT Pathway

You, Min, Yu, De-Hua, Feng, Gen-Sheng·1999·Molecular and Cellular Biology

Cited by (365)

Items 101–200 of 365

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  17. Repression of interferon-γ-induced inducible nitric oxide synthase (iNOS) gene expression in microglia by sodium butyrate is mediated through specific inhibition of ERK signaling pathways
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  19. Conditional Deletion of Shp2 in the Mammary Gland Leads to Impaired Lobulo-alveolar Outgrowth and Attenuated Stat5 Activation
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  20. Inhibition of IFN-γ-Induced STAT1 Tyrosine Phosphorylation by Human CMV Is Mediated by SHP2
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  24. Engagement of the B-cell antigen receptor activates STAT through Lyn in a Jak-independent pathway
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  31. Phosphorylation of Grb2-Associated Binder 2 on Serine 623 by ERK MAPK Regulates Its Association with the Phosphatase SHP-2 and Decreases STAT5 Activation
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  36. Inhibition of IFN-α signaling by a PKC- and protein tyrosine phosphatase SHP-2-dependent pathway
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  37. Signal transduction by type I interferons.
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  44. Role of the cytoplasmic domains of the type I interferon receptor subunits in signaling
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  45. Vanadate Facilitates Interferon α-mediated Apoptosis That Is Dependent on the Jak/Stat Pathway
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  53. Epithelial Tyrosine Phosphatase SHP-2 Protects against Intestinal Inflammation in Mice
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  58. Phosphatase-independent functions of SHP2 and its regulation by small molecule compounds
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