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Antibodies to two major chicken heat shock proteins cross-react with similar proteins in widely divergent species.

Open access
Kelley, P M, Schlesinger, M J·1982·Molecular and Cellular Biology

Abstract

Three of the proteins induced by heat shock of chicken embryo fibroblasts have been purified, and rabbit antibodies have been raised against them. These antibodies have been used in radioimmune precipitation reactions and in a solid-phase immune assay to detect antigenic material in non-heat-shocked chicken tissues and in extracts of widely different species ranging from yeast to mammalian tissue culture cells and human erythrocyte ghosts. Antibodies to two of the major chicken heat shock proteins, chsp89 and chsp70, cross-reacted with proteins of similar molecular weights in normal embryonic and adult chicken tissues and in extracts from widely different organisms. These data provide further evidence for the university of the heat shock response and conservation of proteins induced by this type of stress.

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Metadata

Authors
Kelley, P. M., & Schlesinger, M. J.
Venue
Molecular and Cellular Biology
Published
1982-03
Volume
2
Issue
3
Pages
267-274
ISSN
  • 0270-7306 (ISSN-L)
  • 1098-5549
OpenAlex
W1913296786
Cited by
317
References
0
FWCI
17.35
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Antibodies to two major chicken heat shock proteins cross-react with similar proteins in widely divergent species. https://app.cochat.ai/papers/10.1128/mcb.2.3.267
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Kelley, P. M., & Schlesinger, M. J. (1982). Antibodies to two major chicken heat shock proteins cross-react with similar proteins in widely divergent species. Molecular and Cellular Biology. https://doi.org/10.1128/mcb.2.3.267

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.