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The Heat Shock Respons

Craig, Elizabeth A., Schlesinger, Milton J.·1985·Critical Reviews in Biochemistry

Abstract

The response of cells to a heat shock or other stresses is the activation of a small number of genes which were previously inactive or transcribed at low levels. This response has been observed in a wide variety of bacterial, plant, and animal species. Evidence is accumulating that at least some of the proteins found in diverse species are similar, indicating a conservation of the response and the proteins in evolution. In a number of organisms a strong positive correlation has been found between the presence of heat shock proteins and ability of the organism to withstand thermal stress. This review attempts to assess the available data concerning the homology of proteins in different species, the localization of the proteins in cells, and the relationship between heat shock proteins and thermoresistance.

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Metadata

Authors
Craig, E. A., & Schlesinger, M. J.
Venue
Critical Reviews in Biochemistry
Published
1985-01
Volume
18
Issue
3
Pages
239-280
ISSN
  • 0045-6411 (ISSN-L)
  • 1040-8355
OpenAlex
W2067128865
Cited by
801
References
0
FWCI
9.36
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: The Heat Shock Respons. https://app.cochat.ai/papers/10.3109/10409238509085135
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Craig, E. A., & Schlesinger, M. J. (1985). The Heat Shock Respons. Critical Reviews in Biochemistry. https://doi.org/10.3109/10409238509085135

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