The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
One- and two-step transformations of rat thyroid epithelial cells by retroviral oncogenes.
Open accessAbstract
A system of epithelial cells is described in which it is possible to study the number and the nature of genes capable of conferring the malignant phenotype. Two fully differentiated, hormone-responsive cell lines from rat thyroid glands are presented which are susceptible to one-step or two-step transformation upon infection with several murine acute retroviruses. After infection, both cell lines became independent from their thyrotropic hormone requirement for growth. However, complete transformation was achieved with one of the cell lines (FRTL-5 Cl 2), whereas the other cell line (PC Cl 3) failed to grow in agar and to give rise to tumors in vivo. The latter cell line was susceptible to complete transformation upon cooperation of the v-ras-Ha and the human c-myc oncogenes.
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Cites
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Cited by
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Anoctamin-1/TMEM16A is the major apical iodide channel of the thyrocyte
Twyffels, L., Strickaert, A., Virreira, M., Massart, C., Van Sande, J., Wauquier, C., Beauwens, R., Dumont, J. E., Galietta, L. J., Boom, A., et al. (2014) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00126.2014 · Cited by 77
Expression and function of the homeodomain-containing protein hex in thyroid cells
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Metadata
- Authors
- Fusco, A., Berlingieri, M. T., Di Fiore, P. P., Portella, G., Grieco, M., & Vecchio, G.
- Venue
- Molecular and Cellular Biology
- Publisher
- Informa UK Limited
- Published
- 1987-09
- Volume
- 7
- Issue
- 9
- Pages
- 3365-3370
- ISSN
- 0270-7306 (ISSN-L)
- 1098-5549
- OpenAlex
- W1892956974
- Cited by
- 270
- References
- 20
- FWCI
- 2.25
- Type
- journal article
- Language
- en
- Status
- Retracted
- Open access
- green
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- Fusco, A., Berlingieri, M. T., Di Fiore, P. P., Portella, G., Grieco, M., & Vecchio, G. (1987). One- and two-step transformations of rat thyroid epithelial cells by retroviral oncogenes. Molecular and Cellular Biology. https://doi.org/10.1128/mcb.7.9.3365
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
