The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
A constitutive promoter directs expression of the nerve growth factor receptor gene.
Open accessAbstract
Expression of nerve growth factor receptor is normally restricted to cells derived from the neural crest in a developmentally regulated manner. We analyzed promoter sequences for the human nerve growth factor receptor gene and found that the receptor promoter resembles others which are associated with constitutively expressed genes that have housekeeping and growth-related functions. Unlike these other genes, the initiation of transcription occurred at one major site rather than at multiple sites. The constitutive nature of the nerve growth factor receptor promoter may account for the ability of this gene to be transcribed in a diverse number of heterologous cells after gene transfer. The intron-exon structure of the receptor gene indicated that structural features are precisely divided into discrete domains.
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Cites
Dynan, W. S., & Tjian, R. (1983) · Cell · doi:10.1016/0092-8674(83)90210-6 · Cited by 1,445
Gene transfer and molecular cloning of the rat nerve growth factor receptor
Radeke, M. J., Misko, T. P., Hsu, C., Herzenberg, L. A., & Shooter, E. M. (1987) · Nature · doi:10.1038/325593a0 · Cited by 938
Gene Transfer and Molecular Cloning of the Human NGF Receptor
Chao, M. V., Bothwell, M. A., Ross, A. H., Koprowski, H., Lanahan, A. A., Buck, C. R., & Sehgal, A. (1986) · Science · doi:10.1126/science.3008331 · Cited by 449
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Cited by
An analysis of vertebrate mRNA sequences: intimations of translational control.
Kozak, M. (1991) · The Journal of cell biology · doi:10.1083/jcb.115.4.887 · Cited by 1,635
The “initiator” as a transcription control element
Smale, S. T., & Baltimore, D. (1989) · Cell · doi:10.1016/0092-8674(89)90176-1 · Cited by 1,535
Neurotrophin Signaling Through the P75 Neurotrophin Receptor
Roux, P. (2002) · Progress in Neurobiology · doi:10.1016/s0301-0082(02)00016-3 · Cited by 717
Li, J., & Schmidt, A. M. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.26.16498 · Cited by 525
NRF-1: a trans-activator of nuclear-encoded respiratory genes in animal cells.
Evans, M. J., & Scarpulla, R. C. (1990) · Genes & Development · doi:10.1101/gad.4.6.1023 · Cited by 417
Metadata
- Authors
- Sehgal, A., Patil, N., & Chao, M.
- Venue
- Molecular and Cellular Biology
- Publisher
- Informa UK Limited
- Published
- 1988-08
- Volume
- 8
- Issue
- 8
- Pages
- 3160-3167
- ISSN
- 0270-7306 (ISSN-L)
- 1098-5549
- OpenAlex
- W1809219653
- Cited by
- 286
- References
- 3
- FWCI
- 9.28
- Type
- journal article
- Language
- en
- Open access
- green
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- Sehgal, A., Patil, N., & Chao, M. (1988). A constitutive promoter directs expression of the nerve growth factor receptor gene. Molecular and Cellular Biology. https://doi.org/10.1128/mcb.8.8.3160
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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