Cited by 1,013Probiotics and Fermented FoodsReproductive tract infections researchGut microbiota and health

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Genes and Molecules of Lactobacilli Supporting Probiotic Action

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Lebeer, Sarah, Vanderleyden, Jos, De Keersmaecker, Sigrid C. J.·2008·Microbiology and Molecular Biology Reviews

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Abstract

SUMMARY: Lactobacilli have been crucial for the production of fermented products for centuries. They are also members of the mutualistic microbiota present in the human gastrointestinal and urogenital tract. Recently, increasing attention has been given to their probiotic, health-promoting capacities. Many human intervention studies demonstrating health effects have been published. However, as not all studies resulted in positive outcomes, scientific interest arose regarding the precise mechanisms of action of probiotics. Many reported mechanistic studies have addressed mainly the host responses, with less attention being focused on the specificities of the bacterial partners, notwithstanding the completion of Lactobacillus genome sequencing projects, and increasing possibilities of genomics-based and dedicated mutant analyses. In this emerging and highly interdisciplinary field, microbiologists are facing the challenge of molecular characterization of probiotic traits. This review addresses the advances in the understanding of the probiotic-host interaction with a focus on the molecular microbiology of lactobacilli. Insight into the molecules and genes involved should contribute to a more judicious application of probiotic lactobacilli and to improved screening of novel potential probiotics.

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Items 201–293 of 293

S-layer protein gene of Lactobacillus brevis: cloning by polymerase chain reaction and determination of the nucleotide sequence
Vidgrén, G., Palva, I., Pakkanen, R., Lounatmaa, K., & Palva, A. (1992) · Journal of Bacteriology · doi:10.1128/jb.174.22.7419-7427.1992 · Cited by 148
Genomic and Genetic Characterization of the Bile Stress Response of ProbioticLactobacillus reuteriATCC 55730
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Glucosyltransferase A (GtfA) and inulosucrase (Inu) of Lactobacillus reuteri TMW1.106 contribute to cell aggregation, in vitro biofilm formation, and colonization of the mouse gastrointestinal tract
Walter, J., Schwab, C., Loach, D. M., Gänzle, M. G., & Tannock, G. W. (2008) · Microbiology · doi:10.1099/mic.0.2007/010637-0 · Cited by 148
DNA micro-array-based identification of bile-responsive genes in Lactobacillus plantarum
Bron, P. A., Douwe Molenaar, B., de Vos, W. M., & Kleerebezem, M. (2006) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2006.02891.x · Cited by 147
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Bender, M. H., Cartee, R. T., & Yother, J. (2003) · Journal of Bacteriology · doi:10.1128/jb.185.20.6057-6066.2003 · Cited by 147
Comparative and Functional Analysis of Sortase-Dependent Proteins in the Predicted Secretome of Lactobacillus salivarius UCC118
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G-CSF-mediated inhibition of JNK is a key mechanism for Lactobacillus rhamnosus-induced suppression of TNF production in macrophages
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Kullen, M. J., & Klaenhammer, T. R. (1999) · Molecular Microbiology · doi:10.1046/j.1365-2958.1999.01557.x · Cited by 139
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Morona, J. K., Miller, D. C., Morona, R., & Paton, J. C. (2004) · The Journal of Infectious Diseases · doi:10.1086/383352 · Cited by 139
Bile salts and cholesterol induce changes in the lipid cell membrane of Lactobacillus reuteri
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S-layer protein of Lactobacillus acidophilus ATCC 4356: purification, expression in Escherichia coli, and nucleotide sequence of the corresponding gene
Boot, H. J., Kolen, C. P. A. M., van Noort, J. M., & Pouwels, P. H. (1993) · Journal of Bacteriology · doi:10.1128/jb.175.19.6089-6096.1993 · Cited by 136
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d ‐Alanyl ester depletion of teichoic acids in Lactobacillus reuteri 100‐23 results in impaired colonization of the mouse gastrointestinal tract
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High-Level Folate Production in Fermented Foods by the B 12 Producer Lactobacillus reuteri JCM1112
dos Santos, F. B., Wegkamp, A., de Vos, W. M., Smid, E. J., & Hugenholtz, J. (2008) · Applied and Environmental Microbiology · doi:10.1128/aem.02719-07 · Cited by 134
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Angelis, M. D., Bini, L., PALLINI, V., Cocconcelli, P. S., & Gobbetti, M. (2001) · Microbiology · doi:10.1099/00221287-147-7-1863 · Cited by 131
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Effects of on genes expression pattern in small bowel mucosa
Caro, S. D., TAO, H., Grillo, A., Elia, C., Gasbarrini, A., Sepulveda, A. R., & Gasbarrini, A. (2005) · Digestive and Liver Disease · doi:10.1016/j.dld.2004.12.008 · Cited by 130
The intracellular function of extracellular signaling peptides
Lazazzera, B. A. (2001) · Peptides · doi:10.1016/s0196-9781(01)00488-0 · Cited by 130
Genetic Analysis of Two Bile Salt Hydrolase Activities in Lactobacillus acidophilus NCFM
McAuliffe, O. E., Cano, R. J., & Klaenhammer, T. R. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.8.4925-4929.2005 · Cited by 126
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Walter, J., Heng, N. C. K., Hammes, W. P., Loach, D. M., Tannock, G. W., & Hertel, C. (2003) · Applied and Environmental Microbiology · doi:10.1128/aem.69.4.2044-2051.2003 · Cited by 126
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Azcárate-Peril, M. A., McAuliffe, O. E., Altermann, E., Lick, S., Russell, W. M., & Klaenhammer, T. R. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.10.5794-5804.2005 · Cited by 125
Extracellular proteins of Lactobacillus crispatus enhance activation of human plasminogen
Kainulainen, V., Edelman, S., Antikainen, J., Baumann, M., Lähteenmäki, K., & Korhonen, T. (2007) · Microbiology · doi:10.1099/mic.0.2006/000901-0 · Cited by 125
Streptococcus pneumoniaeCapsule Biosynthesis Protein CpsB Is a Novel Manganese-Dependent Phosphotyrosine-Protein Phosphatase
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Lipoteichoic Acids fromLactobacillus johnsoniiStrain La1 andLactobacillus acidophilusStrain La10 Antagonize the Responsiveness of Human Intestinal Epithelial HT29 Cells to Lipopolysaccharide and Gram-Negative Bacteria
Vidal, K., Donnet‐Hughes, A., & Granato, D. (2002) · Infection and Immunity · doi:10.1128/iai.70.4.2057-2064.2002 · Cited by 125
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Vélez, M. P., Verhoeven, T. L. A., Draing, C., von Aulock, S., Pfitzenmaier, M., Geyer, A., Lambrichts, I., Grangette, C., Pot, B., Vanderleyden, J., et al. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.02083-06 · Cited by 125
Self-citation
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Walter, J., Chagnaud, P., Tannock, G. W., Loach, D. M., Bello, F. D., Jenkinson, H. F., Hammes, W. P., & Hertel, C. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.2.979-986.2005 · Cited by 122
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Péant, B., LaPointe, G., Gilbert, C., Atlan, D., Ward, P., & Roy, D. (2005) · Microbiology · doi:10.1099/mic.0.27852-0 · Cited by 122
Chemical, physical and enzymatic pre-treatments of probiotic lactobacilli alter their adhesion to human intestinal mucus glycoproteins
Tuomola, E., Ouwehand, A. C., & Salminen, S. (2000) · International Journal of Food Microbiology · doi:10.1016/s0168-1605(00)00319-6 · Cited by 119
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Durant, J. A., Corrier, D. E., & Ricke, S. C. (2000) · Journal of Food Protection · doi:10.4315/0362-028x-63.5.573 · Cited by 118
Spatial and Temporal Expression of Lactobacillus plantarum Genes in the Gastrointestinal Tracts of Mice
Marco, M. L., Bongers, R. S., de Vos, W. M., & Kleerebezem, M. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.01475-06 · Cited by 117
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Goh, Y. J., Lee, J.-H., & Hutkins, R. W. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.00805-07 · Cited by 117
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Ventura, M., Janković, I., Walker, D. C., Pridmore, R. D., & Zink, R. (2002) · Applied and Environmental Microbiology · doi:10.1128/aem.68.12.6172-6181.2002 · Cited by 116
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dos Santos, F. B., Vera, J. L., van der Heijden, R. T. J. M., de Valdez, G. F., de Vos, W. M., Sesma, F. J. M., & Hugenholtz, J. (2008) · Microbiology · doi:10.1099/mic.0.2007/011569-0 · Cited by 113
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Tannock, G. W., Ghazally, S., Walter, J., Loach, D. M., Brooks, H. J. L., Cook, G. M., Surette, M. G., Simmers, C., Bremer, P. J., Bello, F. D., et al. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.12.8419-8425.2005 · Cited by 107
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O’Mahony, L., O'Callaghan, L., McCarthy, J., Shilling, D., Scully, P., Sibartie, S., Kavanagh, E., Kirwan, W. O., Redmond, H. P., Collins, J. K., et al. (2005) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00112.2005 · Cited by 105
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Lorca, G. L., Torino, M. I., de Valdez, G. F., & Ljungh, Å. (2002) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2002.tb10982.x · Cited by 102
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Boyle, R. J., & Tang, M. L. K. (2006) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2006.02472.x · Cited by 98
Adhesins and invasins of pathogenic Escherichia coli
Bouguénec, C. L. (2005) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2005.07.001 · Cited by 98
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Voltan, S., Castagliuolo, I., Elli, M., Longo, S., Brun, P., D'Incà, R., Porzionato, A., Macchi, V., Palù, G., Sturniolo, G. C., et al. (2007) · Clinical and Vaccine Immunology · doi:10.1128/cvi.00079-07 · Cited by 96
Constraints on detection of autoinducer-2 (AI-2) signalling molecules using Vibrio harveyi as a reporter
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Self-citation
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Minić, Z., Marie, C., Delorme, C., Faurie, J., Mercier, G., Ehrlich, S. D., & Renault, P. (2007) · Journal of Bacteriology · doi:10.1128/jb.01122-06 · Cited by 95
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Formstone, A., Carballido‐López, R., Noirot, P. H., Errington, J., & Scheffers, D. (2007) · Journal of Bacteriology · doi:10.1128/jb.01394-07 · Cited by 92
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Stephenson, A. E., Wu, H., Novák, J., Tomana, M., Mintz, K. P., & Fives-Taylor, P. M. (2002) · Molecular Microbiology · doi:10.1046/j.1365-2958.2002.02725.x · Cited by 89
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Goh, Y. J., Zhang, C., Benson, A. K., Schlegel, V. L., Lee, J.-H., & Hutkins, R. W. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.00877-06 · Cited by 89
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Iliev, I. D., Kitazawa, H., Shimosato, T., Katoh, S., Morita, H., He, F., Hosoda, M., & Saito, T. (2005) · Cellular Microbiology · doi:10.1111/j.1462-5822.2004.00470.x · Cited by 85
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Sturme, M. H. J., Francke, C., Siezen, R. J., de Vos, W. M., & Kleerebezem, M. (2007) · Microbiology · doi:10.1099/mic.0.2007/012831-0 · Cited by 85
The effect of low pH on protein expression by the probiotic bacterium Lactobacillus reuteri
Lee, K., Lee, H., Pi, K., & Choi, Y. (2008) · PROTEOMICS · doi:10.1002/pmic.200700663 · Cited by 80
The S-layer gene of Lactobacillus helveticus CNRZ 892: cloning, sequence and heterologous expression
Callegari, M. L., Riboli, B., Sanders, J.-W., Cocconcelli, P. S., Kok, J., Venema, G., & Morelli, L. (1998) · Microbiology · doi:10.1099/00221287-144-3-719 · Cited by 80
Prebiotics enhance survival and prolong the retention period of specific probiotic inocula in an in vivo murine model
Su, P., Henriksson, A., & Mitchell, H. M. (2007) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2007.03469.x · Cited by 75
Characterization of the tre Locus and Analysis of Trehalose Cryoprotection in Lactobacillus acidophilus NCFM
Duong, T., Barrangou, R., Russell, W. M., & Klaenhammer, T. R. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.72.2.1218-1225.2006 · Cited by 72
Impact of luxS and Suppressor Mutations on the Gastrointestinal Transit of Lactobacillus rhamnosus GG
Lebeer, S., Claes, I. J. J., Verhoeven, T. L. A., Shen, C., Lambrichts, I., Ceuppens, J. L., Vanderleyden, J., & Keersmaecker, S. C. J. D. (2008) · Applied and Environmental Microbiology · doi:10.1128/aem.00133-08 · Cited by 72
Self-citation
Sucrose utilization and impact of sucrose on glycosyltransferase expression in Lactobacillus reuteri
Schwab, C., Walter, J., Tannock, G. W., Vogel, R. F., & Gänzle, M. G. (2007) · Systematic and Applied Microbiology · doi:10.1016/j.syapm.2007.03.007 · Cited by 70
Proteomic analysis of the effect of bile salts on the intestinal and probiotic bacterium Lactobacillus reuteri
Lee, K.-B., Lee, H., & Choi, Y. (2008) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2008.07.1788 · Cited by 66
Gene Expression of Commensal Lactobacillus johnsonii Strain NCC533 during In Vitro Growth and in the Murine Gut
Denou, E., Berger, B. W., Barretto, C., Panoff, J.-M., Arigoni, F., & Brüssow, H. (2007) · Journal of Bacteriology · doi:10.1128/jb.00991-07 · Cited by 66
d -Alanyl Ester Depletion of Teichoic Acids in Lactobacillus plantarum Results in a Major Modification of Lipoteichoic Acid Composition and Cell Wall Perforations at the Septum Mediated by the Acm2 Autolysin
Palumbo, E., Deghorain, M., Cocconcelli, P. S., Kleerebezem, M., Geyer, A., Härtung, T., Morath, S., & Pascal Hols, A. (2006) · Journal of Bacteriology · doi:10.1128/jb.188.10.3709-3715.2006 · Cited by 64
Transformation of Folate-Consuming Lactobacillus gasseri into a Folate Producer
Wegkamp, A., Starrenburg, M. J. C., de Vos, W. M., Hugenholtz, J., & Sybesma, W. (2004) · Applied and Environmental Microbiology · doi:10.1128/aem.70.5.3146-3148.2004 · Cited by 64
Genetic Analysis of Postpartum Measures of Luteal Activity in Dairy Cows
Petersson, K.-J., Berglund, B., Strandberg, E., Gustafsson, H., Flint, A. P. F., Woolliams, J. A., & Royal, M. D. (2007) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(07)72644-9 · Cited by 63
The cell surface of Lactobacillus reuteri ATCC 55730 highlighted by identification of 126 extracellular proteins from the genome sequence
Båth, K., Roos, S., Wall, T., & Jonsson, H. (2005) · FEMS Microbiology Letters · doi:10.1016/j.femsle.2005.09.042 · Cited by 62
Investigation of the Functional Role of Ctp Proteins in the Cyanobacterium Synechocystis sp. PCC 6803
Ivleva, N. B., Сидорук, К. В., Pakrasi, H. B., & Shestakov, S. V. (2002) · Microbiology · doi:10.1023/a:1019845610873 · Cited by 57
Flow Cytometric Testing of Green Fluorescent Protein-TaggedLactobacillus rhamnosusGG for Response to Defensins
Keersmaecker, S. C. J. D., Braeken, K., Verhoeven, T. L. A., Vélez, M. P., Lebeer, S., Vanderleyden, J., & Pascal Hols, A. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.02605-05 · Cited by 51
Self-citation
Identification and phenotypic characterization of the cell-division protein CdpA
Altermann, E., Buck, B. L., Cano, R. J., & Klaenhammer, T. R. (2004) · Gene · doi:10.1016/j.gene.2004.08.004 · Cited by 51
The uvrA gene is involved in oxidative and acid stress responses in Lactobacillus helveticus CNBL1156
Cappa, F., Cattivelli, D., & Cocconcelli, P. S. (2005) · Research in Microbiology · doi:10.1016/j.resmic.2005.06.003 · Cited by 50
Differential Activities of FourLactobacillus caseiPromoters during Bacterial Transit through the Gastrointestinal Tracts of Human-Microbiota-Associated Mice
Oozeer, R., Furet, J. P., Goupil-Feuillerat, N., Anba‐Mondoloni, J., Mengaud, J., & Corthier, G. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.3.1356-1363.2005 · Cited by 46
Identification of an operon and inducing peptide involved in the production of lactacin B by Lactobacillus acidophilus
Dobson, A., Sanozky-Dawes, R., & Klaenhammer, T. R. (2007) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2007.03417.x · Cited by 44
The d ‐alanine content of lipoteichoic acid is crucial for Lactobacillus plantarum‐mediated protection from visceral pain perception in a rat colorectal distension model
Duncker, S., Wang, L., Pascal Hols, A., & Bienenstock, J. (2008) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2008.01085.x · Cited by 44
Characterization of the protein-synthesis dependent adaptive acid tolerance response in Lactobacillus acidophilus.
Lorca, G. L., de Valdez, G. F., & Ljungh, Å. (2002) · PubMed · Cited by 44
Two-component signal-transducing systems involved in stress responses and vancomycin susceptibility in Lactobacillus sakei
Morel-Deville, F., Fauvel, F., & Morel, P. (1998) · Microbiology · doi:10.1099/00221287-144-10-2873 · Cited by 42
Peptidoglycan structure of Lactobacillus casei, a species highly resistant to glycopeptide antibiotics
Billot-Klein, D., Legrand, R., Schoot, B. M., van HEIJENOORT, J., & Gutmann, L. (1997) · Journal of Bacteriology · doi:10.1128/jb.179.19.6208-6212.1997 · Cited by 41
Dynamics of competitive population abundance of Lactobacillus plantarum ivi gene mutants in faecal samples after passage through the gastrointestinal tract of mice
Bron, P. A., Meijer, M., Bongers, R. S., de Vos, W. M., & Kleerebezem, M. (2007) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2007.03376.x · Cited by 40
Reassembly of a regularly arranged protein in the cell wall of Lactobacillus buchneri and its reattachment to cell walls: chemical modification studies.
Masuda, K., & Kawata, T. (1985) · PubMed · Cited by 38
Long Nocturnal Dialysis
Alloatti, S., Molino, A. R., Manes, M., Bonfant, G., & Pellù, V. (2002) · Blood Purification · doi:10.1159/000066955 · Cited by 37
Proteomic investigation of the aggregation phenomenon in Lactobacillus crispatus
Siciliano, R. A., Cacace, G., Mazzeo, M. F., Morelli, L., Elli, M., Rossi, M., & Malorni, A. (2007) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2007.11.007 · Cited by 36
Gut osmolarity: A key environmental cue initiating the gastrointestinal phase of Listeria monocytogenes infection?
Sleator, R. D., Clifford, T., & Hill, C. (2007) · Medical Hypotheses · doi:10.1016/j.mehy.2007.02.028 · Cited by 36
Immunoadjuvant activities of peptidoglycan subunits from the cell walls of Staphyloccus aureus and Lactobacillus plantarum.
Kotani, S., Watanabe, Y., Shimono, T., Kinoshita, F., & Narita, T. (1975) · PubMed · Cited by 35
Induction of Heavy-Metal-Transporting CPX-Type ATPases during Acid Adaptation in Lactobacillus bulgaricus
Penaud, S., Fernandez, A., Boudebbouze, S., Ehrlich, S. D., Maguin, E., & van de Guchte, M. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.01109-06 · Cited by 35
Towards a proteomic map of Lactococcus lactis NCDO 763
Anglade, P., Demey, E., Labas, V., Caër, J. L., & Chich, J. (2000) · Electrophoresis · doi:10.1002/1522-2683(20000701)21:12 · Cited by 26
The microecology of lactobacilli in the gastrointestinal tract.
Walter, J., & Tannock, G. W. (2005) · Cited by 22
Repression of the Locus of the Enterocyte Effacement-Encoded Regulator of Gene Transcription of Escherichia coli O157:H7 by Lactobacillus reuteri Culture Supernatants Is LuxS and Strain Dependent
Jelčić, I., Hüfner, E., Schmidt, H., & Hertel, C. (2008) · Applied and Environmental Microbiology · doi:10.1128/aem.00072-08 · Cited by 14
Exopolysaccharide production by intestinal lactobacilli.
Gänzle, M. G., & Schwab, C. (2005) · Systematic and Applied Microbiology · Cited by 10
Beyond genome sequences: approaches to genome-wide analysis of gut bacteria.
Fisseha, M., Arigoni, F., & Tannock, G. W. (2005) · Cited by 4
Assessment of Lactobacillus species colonizing the vagina of apparently healthy Nigerian women, using PCR-DGGE and 16S rRNA gene sequencing
Anukam, K. C., Osazuwa, E. O., Ahonkhai, I., & Reid, G. (2006) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-005-4508-6 · Cited by 3
Microbial ecology of the neonatal gastrointestinal tract
Tapia, I. J. A. R. (2002) · Cited by 2
Heteropolysaccharides from lactic acid bacteria
Vuyst, L. D. (1999) · FEMS Microbiology Reviews · doi:10.1016/s0168-6445(98)00042-4

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Yan, F., C. Vanderpool, H. Cao, and D. B. Polk. 2007. Soluble proteins produced by Lactobacillus rhamnosus GG (LGG) activate EGF receptor to regulate the anti-apoptotic response in intestinal epithelial cells. Gastroenterology132:A102-A103.

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Lebeer, S., Vanderleyden, J., & De Keersmaecker, S. C. J. (2010) · Nature Reviews Microbiology · doi:10.1038/nrmicro2297 · Cited by 1,062
Self-citation
The international scientific association for probiotics and prebiotics (ISAPP) consensus statement on fermented foods
Marco, M. L., Sanders, M. E., Gänzle, M., Arrieta, M. C., Cotter, P. D., De Vuyst, L., Hill, C., Holzapfel, W., Lebeer, S., Merenstein, D., et al. (2021) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-020-00390-5 · Cited by 937
Self-citation
Prebiotics in aquaculture: a review
Ringø, E., Olsen, R. E., Gifstad, T. Ø., Dalmo, R. A., Amlund, H., HEMRE, G.-I., & Bakke, A. M. (2010) · Aquaculture Nutrition · doi:10.1111/j.1365-2095.2009.00731.x · Cited by 755
Role of Lactobacillus reuteri in Human Health and Diseases
Mu, Q., Tavella, V. J., & Luo, X. M. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.00757 · Cited by 744
Comparative genomic analysis of Lactobacillus rhamnosus GG reveals pili containing a human- mucus binding protein
Kankainen, M., Paulin, L., Tynkkynen, S., von Ossowski, I., Reunanen, J., Partanen, P., Satokari, R., Vesterlund, S., Hendrickx, A. P. A., Lebeer, S., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0908876106 · Cited by 740
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Authors: Lebeer, S., Vanderleyden, J., & De Keersmaecker, S. C. J.
Affiliations: KU Leuven (BE)
Centre of Microbial and Plant Genetics, K. U. Leuven, Kasteelpark Arenberg 20, 3001 Leuven, Belgium
ORCID: Lebeer, Sarah
Venue: Microbiology and Molecular Biology Reviews
Publisher: American Society for Microbiology
Published: 2008-12
Volume: 72
Issue: 4
Pages: 728-764
ISSN: 1092-2172 (ISSN-L)
1098-5557
DOI: 10.1128/mmbr.00017-08
PMC: PMC2593565
OpenAlex: W2100189539
Cited by: 1,013
References: 290
Citations by year: 2026: 62 · 2025: 55 · 2024: 51 · 2023: 53 · 2022: 73 · 2021: 66 · 2020: 82 · 2019: 65 · 2018: 61 · 2017: 62 · 2016: 40 · 2015: 62 · 2014: 63 · 2013: 53 · 2012: 55
FWCI: 4.71
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: journals.asm.org/non-commercial-tdm-license (tdm)
Locations: Microbiology and Molecular Biology Reviews (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Lirias (submittedVersion, other-oa)
Funders: Fonds Wetenschappelijk Onderzoek
Vlaamse regering
Topics: Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Keywords: lactobacilli, probiotics, probiotic mechanisms of action, mutant analysis, probiotic screening, fermented foods, gut microbiota, urogenital microbiota
MeSH terms: Animals, Food Microbiology, Genes, Bacterial, Humans, Intestines, Lactobacillus, Probiotics

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Genes and Molecules of Lactobacilli Supporting Probiotic Action

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