Cited by 160Evolution and Genetic DynamicsBacterial Genetics and BiotechnologyMicrobial Community Ecology and Physiology

The DOI matches its Crossref record; 385 of the 385 references it cites were found in a registry or an index.

Culture History and Population Heterogeneity as Determinants of Bacterial Adaptation: the Adaptomics of a Single Environmental Transition

Open access

Ryall, Ben, Eydallin, Gustavo, Ferenci, Thomas·2012·Microbiology and Molecular Biology Reviews

DOI 10.1128/mmbr.05028-11PMC PMC3429624

Open this paper in CoChat — free account Open PDF

Abstract

SUMMARY: Diversity in adaptive responses is common within species and populations, especially when the heterogeneity of the frequently large populations found in environments is considered. By focusing on events in a single clonal population undergoing a single transition, we discuss how environmental cues and changes in growth rate initiate a multiplicity of adaptive pathways. Adaptation is a comprehensive process, and stochastic, regulatory, epigenetic, and mutational changes can contribute to fitness and overlap in timing and frequency. We identify culture history as a major determinant of both regulatory adaptations and microevolutionary change. Population history before a transition determines heterogeneities due to errors in translation, stochastic differences in regulation, the presence of aged, damaged, cheating, or dormant cells, and variations in intracellular metabolite or regulator concentrations. It matters whether bacteria come from dense, slow-growing, stressed, or structured states. Genotypic adaptations are history dependent due to variations in mutation supply, contingency gene changes, phase variation, lateral gene transfer, and genome amplifications. Phenotypic adaptations underpin genotypic changes in situations such as stress-induced mutagenesis or prophage induction or in biofilms to give a continuum of adaptive possibilities. Evolutionary selection additionally provides diverse adaptive outcomes in a single transition and generally does not result in single fitter types. The totality of heterogeneities in an adapting population increases the chance that at least some individuals meet immediate or future challenges. However, heterogeneity complicates the adaptomics of single transitions, and we propose that subpopulations will need to be integrated into future population biology and systems biology predictions of bacterial behavior.

Integrity signals

Registry

Crossref · 10.1128/mmbr.05028-11

Cites

385 of 385 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

1 retracted

RETRACTED: Bacterial persistence by RNA endonucleases
Maisonneuve, E., Shakespeare, L. J., Jørgensen, M. G., & Gerdes, K. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1100186108 · Cited by 473
Retracted
Escherichia coli and Salmonella :cellular and molecular biology
Neidhardt, F. C. (1996) · ASM Press eBooks · Cited by 8,197
DNA Repair and Mutagenesis
Friedberg, E. C., Walker, G. C., Siede, W., Wood, R. D., Schultz, R. A., & Ellenberger, T. (2005) · doi:10.1128/9781555816704 · Cited by 5,683
QUORUM SENSING: Cell-to-Cell Communication in Bacteria
Waters, C. M., & Bassler, B. L. (2005) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.21.012704.131001 · Cited by 3,989
Mechanisms of biofilm resistance to antimicrobial agents
Mah, T.-F. C., & O'Toole, G. A. (2001) · Trends in Microbiology · doi:10.1016/s0966-842x(00)01913-2 · Cited by 3,921
Bacterial Persistence as a Phenotypic Switch
Balaban, N. Q., Merrin, J., Chait, R., Kowalik, L., & Leibler, S. (2004) · Science · doi:10.1126/science.1099390 · Cited by 2,952
A Molecular View of Microbial Diversity and the Biosphere
Pace, N. R. (1997) · Science · doi:10.1126/science.276.5313.734 · Cited by 2,797
Physiological heterogeneity in biofilms
Stewart, P. S., & Franklin, M. J. (2008) · Nature Reviews Microbiology · doi:10.1038/nrmicro1838 · Cited by 2,483
Quantifying E. coli Proteome and Transcriptome with Single-Molecule Sensitivity in Single Cells
Taniguchi, Y., Choi, P. J., Li, G.-W., Chen, H., Babu, M., Hearn, J., Emili, A., & Xie, X. S. (2010) · Science · doi:10.1126/science.1188308 · Cited by 1,982 · cited 1×
“What is revealed is the high level of noise in gene expression across the whole genome (323).”
Background
Rates of spontaneous mutation
Drake, J. W., Charlesworth, B., Charlesworth, D., & Crow, J. F. (1998) · Genetics · doi:10.1093/genetics/148.4.1667 · Cited by 1,932

Flagged first, then by citations

Show all 385 references

Research works printed but not linked: 4

CampbellAM. 1996. Bacteriophages, p 2325–2338. In NeidhardtFC (ed), Escherichia coli and Salmonella: cellular and molecular biology, 2nd ed. American Society for Microbiology, Washington, DC.
CashelM GentryD HernandezVJ VinellaD. 1996. The stringent response, p 1458–1496. In NeidhardtFC (ed), Escherichia coli and Salmonella: cellular and molecular biology, 2nd ed. American Society for Microbiology, Washington, DC.
MaaloeO KjeldgaardNO. 1966. Control of macromolecular synthesis. WA Benjamin, New York, NY.
NeidhardtFC. (ed). 1996. Escherichia coli and Salmonella: cellular and molecular biology, 2nd ed. ASM Press, Washington, DC.

Sorted by citations

Items 101–160 of 160

Systematic annotation of hyper-variability hotspots in phage genomes and plasmidsPreprint
Egorov, A. A., Hauryliuk, V., & Atkinson, G. C. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.10.15.618418 · Cited by 10
Glacier clear ice bands indicate englacial channel microbial distribution
Varliero, G., Holland, A., Barker, G., Yallop, M. L., Fountain, A. G., & Anesio, A. M. (2021) · Journal of Glaciology · doi:10.1017/jog.2021.30 · Cited by 7
Isolation and characterization of synthetic pyrethroids-degrading bacterial strains from agricultural soil
Uzma, B., Ali, F., Qureshi, N. A., Shakeela, Q., Asima, B., Ahmed, S., Hayat, A., & Rehman, M. (2023) · Brazilian Journal of Biology · doi:10.1590/1519-6984.271790 · Cited by 7
Giving the cells what they need when they need it: Biosensor‐based feeding control
Kinet, R., Richelle, A., Colle, M., Demaegd, D., von Stosch, M., Sanders, M., Sehrt, H., Delvigne, F., & Goffin, P. (2024) · Biotechnology and Bioengineering · doi:10.1002/bit.28657 · Cited by 7
Microbe-plant interactions of Escherichia coli and Salmonella
Holden, N. J., & Barak, J. D. (2025) · EcoSal Plus · doi:10.1128/ecosalplus.esp-0018-2023 · Cited by 6
Differential Pneumococcal Growth Features in Severe Invasive Disease Manifestations
Arends, D. W., Alkema, W. B. L., Putri, I. H., Jongh, C. E. V. D. G., Eleveld, M. J., Langereis, J. D., de Mast, Q., Meis, J. F. G. M., de Jonge, M. I., & Cremers, A. J. H. (2022) · Microbiology Spectrum · doi:10.1128/spectrum.00050-22 · Cited by 8
Supplemental nutrients stimulate the amplification of carbapenemase-producing Klebsiella pneumoniae (CPKP) in a sink drain in vitro biofilm reactor model
Burgos-Garay, M. L., Santiago, A. J., Kartforosh, L., Kotay, S. M., & Donlan, R. M. (2021) · Biofouling · doi:10.1080/08927014.2021.1915998 · Cited by 6
The Natural Whey Starter Used in the Production of Grana Padano and Parmigiano Reggiano PDO Cheeses: A Complex Microbial Community
Neviani, E. (2024) · Microorganisms · doi:10.3390/microorganisms12122443 · Cited by 5
Pleomorphism drives the lifestyle transitions in bacteria for micro-niche adaptation in biofilm
Dey, S., Nayak, A. K., Dhiman, R., Rajaram, H., & Das, S. (2025) · Reviews in Environmental Science and Bio/Technology · doi:10.1007/s11157-025-09742-6 · Cited by 8
Stress-Driven Tolerance and Persistence of Listeria monocytogenes Across the Farm-to-Fork Continuum
Elbehiry, A., Marzouk, E., & Abalkhail, A. (2026) · Biology · doi:10.3390/biology15040310 · Cited by 6
A single point mutation in the Listeria monocytogenes ribosomal gene rpsU enables SigB activation independently of the stressosome and the anti-sigma factor antagonist RsbV
Ma, X., Tempelaars, M. H., Zwietering, M. H., Boeren, S. A., O'Byrne, C. P., den Besten, H. M. W., & Abee, T. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1304325 · Cited by 5
Essential roles of Lon protease in the morpho-physiological traits of the rice pathogen Burkholderia glumae
Goo, E., & Hwang, I. (2021) · PLoS ONE · doi:10.1371/journal.pone.0257257 · Cited by 5
Pseudomonas aeruginosa as a model bacterium in antiphage defense research
Bae, H., Choi, S.-Y., Ki, H. K., & Cho, Y. (2025) · FEMS Microbiology Reviews · doi:10.1093/femsre/fuaf014 · Cited by 6
Heterogeneous fitness landscape cues, pknG high expression, and phthiocerol dimycocerosate low production of Mycobacterium tuberculosis ATCC25618 rpoB S450L in enriched broth
Rodríguez–Beltrán, E., López, G.-D., Anzola, J. M., Rodríguez–Castillo, J. G., Carazzone, C., & Murcia, M. I. (2021) · Tuberculosis · doi:10.1016/j.tube.2021.102156 · Cited by 4
Evolution of rhizobial siderophore utilization via accessory xeno-siderophore receptors and flexible intake machinery for self-produced siderophores
Si, Y.-W., Feng, M.-D., Yang, B.-S., Liu, Y., Liu, K., Yin, W., Jiao, J., & Tian, C. F. (2025) · The ISME Journal · doi:10.1093/ismejo/wraf280 · Cited by 3
Analysis of Genome Sequences of Coagulase-Negative Staphylococci Isolates from South Africa and Nigeria Highlighted Environmentally Driven Heterogeneity
Maguvu, T. E., Oladipo, A. O., & Bezuidenhout, C. C. (2021) · Journal of Genomics · doi:10.7150/jgen.53019 · Cited by 3
Metabolism of the phase variants of the phototrophic bacterium Rhodobacter sphaeroides
Милько, Е. С., Krasilnikova, E. N., Keppen, O. I., Lebedeva, N. V., & Ivanovsky, R. N. (2014) · Microbiology · doi:10.1134/s0026261714040122 · Cited by 3
Relative importance of the bacteria Brucella, Salmonella, Staphylococcus and other indicator bacteria in some mountain farm waters in West-Cameroon (Central Africa) and the potential role of some environmental factors
Bahebeck, P. N., Nougang, M. E., Nana, P. A., Metsopkeng, C. S., Arfao, A. T., Ewoti, O. V. N., Moungang, L. M., Tamekou, S. L., Pougue, H. B., Pérrière, F., et al. (2020) · World Journal of Advanced Research and Reviews · doi:10.30574/wjarr.2020.8.2.0396 · Cited by 3
Population dynamics and diversity of Synechococcus on the New England Shelf
Hunter‐Cevera, K. R. (2014) · doi:10.1575/1912/6910 · Cited by 3
Pioneering on single-sludge nitrification/denitrification at 50 °C
Vandekerckhove, T. G. L., Boon, N., & Vlaeminck, S. E. (2020) · Chemosphere · doi:10.1016/j.chemosphere.2020.126527 · Cited by 3
The COM-Poisson Process for Stochastic Modeling of Osmotic Inactivation Dynamics of Listeria monocytogenes
Polese, P., Torre, M. D., & Stecchini, M. L. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.681468 · Cited by 3
Effect of Citric Acid on Viability, Membrane Damage, Efflux Pump Activity, and Growth Recovery of Vibrio alginolyticus and Vibrio cholerae Strains
Lucero‐Mejía, J. E., Godínez‐Oviedo, A., Gómez‐Baltazar, A., Romero‐Gómez, S. D. J., Vázquez‐Garcidueñas, M. S., Vázquez‐Marrufo, G., & Hernández‐Iturriaga, M. (2025) · Journal of Food Protection · doi:10.1016/j.jfp.2025.100534 · Cited by 2
Heterogeneity in isogenic bacteria populations and modern technologies of cell phenotyping
Andryukov, B. G., Тимченко, Н. Ф., Lyapun, I. N., Павловна, Б. М., & Matosova, E. V. (2021) · Journal of microbiology epidemiology immunobiology · doi:10.36233/0372-9311-33 · Cited by 2
Enhanced Growth of Pilin-Deficient Geobacter sulfurreducens Mutants in Carbon Poor and Electron Donor Limiting Conditions
Semenec, L., Vergara, I. A., Laloo, A. E., Mathews, E. R., Bond, P. L., & Franks, A. E. (2019) · Microbial Ecology · doi:10.1007/s00248-019-01316-8 · Cited by 2
Quantitative and ecological aspects of Listeria monocytogenes population heterogeneity
Metselaar, K. I. (2016) · doi:10.18174/376546 · Cited by 2
From the Single Bacterial Cell to the Microbial Community: A Round Trip to Better Understand the Secrets of Complex Microbiological Ecosystems
Erasmo, N. (2024) · International Journal of Clinical Microbiology and Biochemical Technology · doi:10.29328/journal.ijcmbt.1001029 · Cited by 1
Comparative analysis of phenotype and gene expression in Saccharomyces cerevisiae grown in solid versus liquid culture formats
Liu, J., Wang, Q., Lin, J., Lei, J., Xu, Z., Dai, J., & Wang, K. (2026) · BMC Microbiology · doi:10.1186/s12866-026-04855-6 · Cited by 1
The process of bacterial population splitting into dissociants and long-term batch cultivation of bacteria
Милько, Е. С., & Milko, D. M. (2014) · Applied Biochemistry and Microbiology · doi:10.1134/s0003683814040097 · Cited by 1
Antagonismo e inhibición de la comunicación bacteriana en bacterias cultivables aisladas de esponjas del Caribe Colombiano con Biofouling y sin Biofouling
Toro, B., & Daniela, A. (2019) · Cited by 1
Comprehensive study of Biginelli's compounds show antibacterial activity against Vibrio parahaemolyticus of two strains: In vitro and computational approaches
Paringamalai, N., Tajudeen, S. S., Ibrahim, A. M., Ahmed, J., Ramalingam, K., & Vijayakumar, S. (2024) · Microbial Pathogenesis · doi:10.1016/j.micpath.2024.107213 · Cited by 1
Population-Specific Transcriptomic Shifts Underlie Secondary Metabolic Diversification in Aspergillus flavus and the Domestication of Aspergillus oryzaePreprint
Drott, M. T., Wang, Y., Hatmaker, E. A., Soto, N. M. M., Elmore, J. M., Luciano‐Rosario, D., Yu, J., Rokas, A., Gibbons, J. G., Anna Huttenlocher, A., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.10.02.680074 · Cited by 1
Modélisation de la sporulation de Bacillus subtillis BSB1 et liens physiologiques avec les cinétiques de croissance
Gauvry, E. (2017) · theses.fr (ABES) · doi:10.70675/a3e056a9zdcb1z4fccz967cz68f13803b044 · Cited by 1
Studying the evolution of bacterial micro-organisms by modeling and numerical simulation approaches
Rocabert, C. (2017) · theses.fr (ABES) · doi:10.70675/273b3895z1c44z4ed9z9eccze815e1fa7c7f · Cited by 1
Physiological comparison of cells with high and low alcohol dehydrogenase activities in bacterial populations consuming ethanol
Ivanov, V., Rezaeinejad, S., & Stabnikova, О. (2014) · Annals of Microbiology · doi:10.1007/s13213-014-0945-5
Rampant loss of social traits during domestication of a Bacillus subtilis natural isolatePreprint
Barreto, H. C., Cordeiro, T. N., Henriques, A. O., & Gordo, I. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/751438
A Bayesian Non-parametric Mixed-Effects Model of Microbial PhenotypesPreprint
Tonner, P. D., Darnell, C. L., Bushell, F. M. L., Lund, P. A., Schmid, A., & Schmidler, S. C. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/793174
Metabolomics of epigenetics: A history of the integrome
Bueno, J. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-817613-9.00006-7
Profiling the initial burst of beneficial genetic diversity in clonal cell populations to anticipate evolutionPreprint
Deatherage, D. E., & Barrick, J. E. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.07.10.196832
Molecular evolution of the meningococcal fragments of 7 house-keeping genes
Kharkhal, H. N., Titov, L. P., & Yanovich, O. O. (2020) · Proceedings of the National Academy of Sciences of Belarus Medical series · doi:10.29235/1814-6023-2020-17-3-301-319
Growth response and recovery of Corynebacterium glutamicum colonies on single-cell level upon defined pH stress pulsesPreprint
Täuber, S., Blöbaum, L., Wendisch, V. F., & Grünberger, A. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.02.26.433016
Aislamiento de mutantes rpoB S531L resistentes a rifampicina en Mycobacterium tuberculosis H37Rv ATCC 25618 e identificación de biomarcadores de adaptación
Beltrán, R., & Orlando, É. (2021)
Efeito do glifosato sobre a susceptibilidade a antibióticos em Escherichia coli
Ospino, K. (2022) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.42.2022.tde-07122022-152116
Potential Antibacterial Activity for the 3,4-Dihydropyrimidone Variants Against Mtcc-451 & Vp-S14: Invitro & Insilico Like 2d-Qsar, Molecular Docking, Dft and Adme/T StudiesPreprint
AMEEN, S. T. S., Paringamalai, N., Ibrahim, A. M., Ahmed, J., & Ramalingam, K. (2024) · SSRN Electronic Journal · doi:10.2139/ssrn.4848789
General Characteristics and Properties of Organic Life
Knoflacher, M. (2024) · Springer eBooks · doi:10.1007/978-3-662-69423-7_5
Transfer Learning for Individualized Treatment Rules with Application to Sepsis Patients Data
Wang, A., Wentzlof, K., Rajala, J., Green, M., Zhang, Y., & Yang, S. (2025) · Journal of Data Science · doi:10.6339/25-jds1193
A signal peptide-guided platform for in situ functionalization of bacterial nanocellulose in Komagataeibacter rhaeticusPreprint
Vannas, J., Singh, A., Hannikainen, B., de Assis, M. A., Ledesma‐Amaro, R., Ellis, T., & Mangayil, R. K. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2025.12.15.694344
Single-Cell Sorting to Assess Phage Sensitivity in Heterogeneous Bacterial Populations
Mora-Quilis, L., & Domingo‐Calap, P. (2025) · The microbiomes of humans, animals, plants, and the environment · doi:10.1007/978-3-032-07527-7_8
Mother cells can establish slow-growing lineages in clonal populations since their earliest division cycles
Delgado-Román, I., García-Marcelo, M. J., Ruger-Herreros, C., Delgado-Ramos, L., Singh, A., Chávez, S., & Muñoz-Centeno, M. C. (2026) · Open Biology · doi:10.1098/rsob.250249
An enhanced domestication method for uncultured bacteria
Morrison, A. G., Jackson, R., Freemont, P. S., & Low, H. H. (2026) · ISME Communications · doi:10.1093/ismeco/ycag062
Dynamique des populations et communautés bactériennes au cours de l’hospitalisation et des infections associées aux soins : cas particulier de la chirurgie cardiaque
Romano-Bertrand, S. (2015) · theses.fr (ABES) · doi:10.70675/21d3992az768cz4956z94a2z4484f68f83b1
De l’épidémiologie moléculaire aux analyses fonctionnelles de Brucella chez les ruminants, une approche intégrée pour l’identification et l’étude de la diversité phénotypique d’un genre génétiquement homogène
Holzapfel, M. (2018) · doi:10.70675/30bfaa24zcbb5z471cz9613z6ba51156e147
Modeling the kinetic behaviour, mixing and local transfer pheonmena and biologicial population heterogeneity effects in industrial fermenters
Pigou, M. (2018) · theses.fr (ABES) · doi:10.70675/793dcdc1zd09cz4942z9451zde1bd7c987c3 · Cited by 1
Study on dynamics of microbial collective behaviour using an original machine-ecosystem interaction
Fosseprez, C. (2019) · theses.fr (ABES) · doi:10.70675/7395ef93z0fe1z4bfbz9d5czfce77c6b5e31
Influence of flow on the growth dynamics of microorganisms : microfluidic imaging and modeling
Hubert, A. (2020) · theses.fr (ABES) · doi:10.70675/9c793bf4zd273z43dfza749z750ac4db399c
High growth rates can promote persister cell formation in Pseudomonas aeruginosa
Davies, S., Choudhary, D., Judge, M., Uphoff, S., Griffin, A. S., & Ghoul, M. (2026) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2025.3285
Microorganisms as activators, regulators, and bioindicators of ecosystems
Serwecińska, L., Mankiewicz‐Boczek, J., Bednarek, A., & Font-Nájera, A. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-41596-8.00043-1
Literature
(2026) · Elsevier eBooks · doi:10.1016/b978-0-443-41596-8.32001-5
Inhibition of biofilm formation in Mycobacterium smegmatis by extracts of endophytic fungi from Poikilospermum suaveolens (Blume) Merr)
Pratiwi, R. H., Agusta, A., Nurkanto, A., & Fathoni, A. (2026) · Brazilian Journal of Biology · doi:10.1590/1519-6984.308289
Population-specific transcriptomic shifts underlie secondary metabolic diversification in Aspergillus flavus Link and the domestication of Aspergillus oryzae (Ahlb.)
Drott, M. T., Wang, Y., Hatmaker, E. A., Soto, N. M. M., Elmore, J. M., Luciano‐Rosario, D., Yu, J., Rokas, A., Gibbons, J. G., Anna Huttenlocher, A., et al. (2026) · IMA Fungus · doi:10.3897/imafungus.17.195218
Systems-level orchestration of oxygenic photosynthesis and nitrogen fixation in cyanobacteria
Bandyopadhyay, A., Liberton, M., Bhattacharyya‐Pakrasi, M., Jones, C. M., Muddana, C., Biswas, S., Tang, Y., & Pakrasi, H. B. (2026) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00246-24

Authors: Ryall, B., Eydallin, G., & Ferenci, T.
Affiliations: The University of Sydney (AU)
ORCID: Ferenci, Thomas
Venue: Microbiology and Molecular Biology Reviews
Publisher: American Society for Microbiology
Published: 2012-09
Volume: 76
Issue: 3
Pages: 597-625
ISSN: 1092-2172 (ISSN-L)
1098-5557
DOI: 10.1128/mmbr.05028-11
PMC: PMC3429624
OpenAlex: W2129172649
Cited by: 160
References: 385
Citations by year: 2026: 10 · 2025: 11 · 2024: 15 · 2023: 4 · 2022: 6 · 2021: 15 · 2020: 14 · 2019: 12 · 2018: 11 · 2017: 11 · 2016: 11 · 2015: 14 · 2014: 16 · 2013: 10
FWCI: 1.56
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: journals.asm.org/non-commercial-tdm-license (tdm)
Locations: Microbiology and Molecular Biology Reviews (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Bacterial Genetics and Biotechnology
Physical Sciences › Environmental Science › Ecology › Microbial Community Ecology and Physiology
Keywords: bacterial adaptation, culture history, population heterogeneity, environmental transition, clonal populations, microevolution, epigenetic adaptation, stress-induced mutagenesis, phase variation, horizontal gene transfer, genome amplification, prophage induction, biofilm, bacterial dormancy, population structure (demography), evolutionary contingency
MeSH terms: Adaptation, Physiological, Bacteria, Culture Media, Genotype, Humans, Phenotype, Genetic Variation, Gene Expression Regulation, Bacterial, Bacterial Physiological Phenomena

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Culture History and Population Heterogeneity as Determinants of Bacterial Adaptation: the Adaptomics of a Single Environmental Transition

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks