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Cited by 1,451

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Hepatitis B Virus Biology

Open access
Seeger, Christoph, Mason, William S.·2000·Microbiology and Molecular Biology Reviews

Abstract

SUMMARY: Hepadnaviruses (hepatitis B viruses) cause transient and chronic infections of the liver. Transient infections run a course of several months, and chronic infections are often lifelong. Chronic infections can lead to liver failure with cirrhosis and hepatocellular carcinoma. The replication strategy of these viruses has been described in great detail, but virus-host interactions leading to acute and chronic disease are still poorly understood. Studies on how the virus evades the immune response to cause prolonged transient infections with high-titer viremia and lifelong infections with an ongoing inflammation of the liver are still at an early stage, and the role of the virus in liver cancer is still elusive. The state of knowledge in this very active field is therefore reviewed with an emphasis on past accomplishments as well as goals for the future.

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Metadata

Authors
Seeger, C., & Mason, W. S.
Venue
Microbiology and Molecular Biology Reviews
Published
2000-03
Volume
64
Issue
1
Pages
51-68
ISSN
  • 1092-2172 (ISSN-L)
  • 1098-5557
OpenAlex
W2107057287
Cited by
1,451
References
1
FWCI
6.74
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Hepatitis B Virus Biology. https://app.cochat.ai/papers/10.1128/mmbr.64.1.51-68.2000
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Seeger, C., & Mason, W. S. (2000). Hepatitis B Virus Biology. Microbiology and Molecular Biology Reviews. https://doi.org/10.1128/mmbr.64.1.51-68.2000

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.