Role of Microbiota in the Skin Colonization of Candida auris
Open accessAbstract
Candida auris is an emerging multidrug-resistant fungal pathogen that can cause life-threatening infections in humans. Unlike other Candida species that colonize the gut, C. auris efficiently colonizes the skin and contaminates the patient's environment, resulting in rapid nosocomial transmission and outbreaks of systemic infections.
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Long-term C. auris skin colonization fosters patient-to-patient transmission and spread in healthcare settings.
“Moreover, long-term skin colonization also fosters transmission from patient to patient and overall spread in healthcare settings (19).”
From <i>Candida auris</i> metabolism and growth preferences in physiologically relevant skin-like conditions (2026) · cites this paper as [19]
The Perspective section says C. auris can spread between patients in healthcare settings and that skin colonization likely facilitates transmission. It does not establish that colonization is long-term or that its duration fosters spread; its reference to long-term care facilities describes the setting, not the duration of colonization. No page number is available in our copy. (LLM, conf=0.83)
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References 24 · Cited by 45
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- Authors
- Tharp, B., Zheng, R., Bryak, G., Litvintseva, A. P., Hayden, M. K., Chowdhary, A., & Thangamani, S.
- Affiliations
- Purdue University West Lafayette (US)
- Centers for Disease Control and Prevention (US)
- Rush University Medical Center (US)
- University of Delhi (IN)
- Corresponding author
- Chowdhary, Anuradha
- Thangamani, Shankar
- Venue
- mSphere
- Publisher
- American Society for Microbiology
- Published
- 2023-02-21
- Volume
- 8
- Issue
- 1
- Pages
- e0062322-e0062322
- ISSN
- 2379-5042 (ISSN-L)
- PMC
- PMC9942586
- OpenAlex
- W4317939754
- Cited by
- 45
- References
- 24
- Citations by year
- 2026: 13 · 2025: 9 · 2024: 16 · 2023: 7
- FWCI
- 9.31
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- mSphere (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Greater South Information System
- Funders
- Centers for Disease Control and Prevention (U54CK000607)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Health Sciences › Medicine › Epidemiology › Nail Diseases and Treatments
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Keywords
- Candida auris, skin microbiome, skin colonization, host-microbe interactions, skin immune system, nosocomial transmission, emerging fungal pathogens, microbiota-based therapy, fungal pathogenesis
- MeSH terms
- Candida auris, Candida, Disease Outbreaks, Humans, Skin
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