The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Cretinism presenting as a pseudotumour
Open accessAbstract
A 43-year-old man from a remote part of India (over 1800 km from our institution), presented with a headache of 3 years duration. He was of short stature, had delayed puberty and was mentally retarded. On evaluation he was detected to have primary hypothyroidism with markedly elevated thyroid-stimulating hormone titres. A CT of the brain revealed a large sellar mass with suprasellar extension into the third ventricle causing obstructive hydrocephalus. Surgical intervention was deferred due to absence of visual impairment and the presence of gross hypothyroidism. The clinical diagnosis of congenital hypothyroidism was confirmed by the absence of radioiodine uptake in the thyroid bed. With thyroid hormone replacement therapy, the 'tumour' underwent significant reduction in size with the resolution of hydrocephalus thereby favouring a potential pituitary pseudotumour. This was an unusual situation of a giant pituitary pseudotumour detected in an adult with untreated congenital hypothyroidism.
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In the review, only one patient was deemed potentially affected by a non-functioning pituitary adenoma within the context of concurrent pituitary hyperplasia.
“In our review, only one patient was deemed potentially affected by a non-functioning pituitary adenoma within the context of concurrent pituitary hyperplasia [40].”
From Pituitary Hyperplasia Due to Longstanding Primary Hypothyroidism: A Case Report and Comprehensive Review of the Literature (2024) · cites this paper as [40]
Citations
Cites
Sarlis, N. J., Brücker-Davis, F., Doppman, J. L., & Skarulis, M. C. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.82.3.3796 · Cited by 83
Neonatal screening for congenital hypothyroidism using the filter paper thyroxine technique.
Desai, M. P., Upadhye, P. S., Colaco, M. P., et al. (1994) · PubMed · Cited by 48
Pituitary thyrotropic adenoma associated with congenital hypothyroidism
Fatourechi, V., Gharib, H., Scheithauer, B. W., et al. (1984) · The American Journal of Medicine · doi:10.1016/0002-9343(84)90302-4 · Cited by 18
EFFECTS OF PROTRACTED HYPOTHYROIDISM ON PITUITARY FUNCTION AND STRUCTURE IN ENDEMIC CRETINISM
BOYAGES, S. C., Halpern, J., MABERLY, G. F., Eastman, C. J., CARR, P., DEZHONG, Y., Chuanyi, Y., & CHENEN, J. (1989) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1989.tb03721.x · Cited by 8
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Research works printed but not linked: 1
- 10.1210/jc.82.3.808 · DOI
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Roux, A., Rosso, D., Cuboni, D., Maccario, M., Grottoli, S., Arvat, E., & Gasco, V. (2024) · Biomedicines · doi:10.3390/biomedicines12061368 · Cited by 9
“In another case, the suspicion of a non-functioning macroadenoma arose, though whether surgical intervention was subsequently performed is not known [40].”
Background
Metadata
- Authors
- Mahesh, D. M., Jebasingh, F. K., Baruah, M. P., & Thomas, N.
- Affiliations
- Christian Medical College, Vellore (IN)
- Department of Endocrinology, Excelcare Hospitals, Guwahati, Assam, India
- Corresponding author
- Thomas, Nihal
- Venue
- BMJ Case Reports
- Publisher
- BMJ
- Published
- 2015-01-09
- Volume
- 2015
- Pages
- bcr2014206124
- ISSN
- 1757-790X (ISSN-L)
- PMC
- PMC4289768
- OpenAlex
- W2080658205
- Cited by
- 2
- References
- 4
- Citations by year
- 2024: 1 · 2016: 1
- FWCI
- 0.29
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- BMJ Case Reports (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Pituitary Gland Disorders and Treatments
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
- Health Sciences › Medicine › Nephrology › Electrolyte and hormonal disorders
- Keywords
- cretinism, congenital hypothyroidism, primary hypothyroidism, obstructive hydrocephalus, sellar mass, thyroid-stimulating hormone, thyroid hormone replacement, delayed puberty, intellectual disability, short stature, radioiodine uptake
- MeSH terms
- Adult, Congenital Hypothyroidism, Diagnosis, Differential, Headache, Humans, India, Male, Pituitary Neoplasms, Thyroxine, Tomography, X-Ray Computed, Treatment Outcome, Hormone Replacement Therapy
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