The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Triphasic response of pituitary stalk injury following TBI: a relevant yet uncommonly recognised endocrine phenomenon
Open accessAbstract
The triphasic response of pituitary stalk injury has previously been described in a minority of patients following intracranial surgery, however, this phenomenon can also occur after traumatic brain injury. We present the case of a 20-year-old male who experienced the triphasic response of pituitary stalk injury (central diabetes insipidus, syndrome of inappropriate antidiuretic hormone and central diabetes insipidus again) after striking his head on a concrete curb. His history and presentation highlight the importance of recognising the distinctive symptoms of each individual stage of pituitary stalk injury, and using the appropriate diagnostic tools and therapies to guide further management.
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The 'triphasic response' (transient DI followed by transient SIADH, sometimes progressing to persistent central DI) has been occasionally described after TBI.
“The 'triphasic response,' in which transient DI is followed by transient SIADH with some patients then progressing to persistent central DI, has been occasionally described after TBI [15, 16].”
From Neuroendocrine Disruptions Following Head Injury (2023) · cites this paper as [16]
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Citations
Cites
Physiology and pathophysiology of the vasopressin-regulated renal water reabsorption
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Posterior pituitary dysfunction after traumatic brain injury
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The natural history of post-traumatic neurohypophysial dysfunction
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Diabetes Insipidus after Traumatic Brain Injury
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Diabetes insipidus as a complication after pituitary surgery
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Management of Electrolyte and Fluid Disorders after Brain Surgery for Pituitary/Suprasellar Tumours
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[Syndrome of inappropriate ADH secretion (SIADH) in hypophyseal tumors].
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Neuroendocrine Disruptions Following Head Injury
Wexler, T. L. (2023) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-023-01263-5 · Cited by 23
Metadata
- Authors
- Goel, A., Farhat, F., Zik, C., & Jeffery, M.
- Affiliations
- Inova Health System (US)
- Corresponding author
- Goel, Ansha
- ORCID
- Venue
- BMJ Case Reports
- Publisher
- BMJ
- Published
- 2018-10-24
- Volume
- 2018
- Pages
- bcr-2018-226725
- ISSN
- 1757-790X (ISSN-L)
- PMC
- PMC6203072
- OpenAlex
- W2898222878
- Cited by
- 11
- References
- 14
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 3 · 2023: 2 · 2021: 1 · 2020: 1
- FWCI
- 0.40
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- BMJ Case Reports (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- HighWire Press Open Archive (submittedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Pituitary Gland Disorders and Treatments
- Health Sciences › Medicine › Nephrology › Electrolyte and hormonal disorders
- Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury and Neurovascular Disturbances
- Keywords
- traumatic brain injury, central diabetes insipidus, syndrome of inappropriate antidiuretic hormone secretion, hypothalamic-pituitary dysfunction
- MeSH terms
- Brain Injuries, Traumatic, Deamino Arginine Vasopressin, Humans, Inappropriate ADH Syndrome, Male, Pituitary Gland, Polyuria, Thirst, Headache Disorders, Diabetes Insipidus, Neurogenic, Antidiuretic Agents, Young Adult
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