Spontaneous portomesenteric thrombosis in a non-cirrhotic patient with SARS-CoV-2 infection
Open accessAbstract
Intra-abdominal thromboses are a poorly characterised thrombotic complication of COVID-19 and are illustrated in this case. A 42-year-old man with chronic hepatitis B (undetectable viral load, FibroScan 7.4 kPa) developed fever and cough in March 2020. 14 days later, he developed right upper quadrant pain. After being discharged with reassurance, he re-presented with worsening pain on symptom day 25. Subsequent abdominal ultrasound suggested portal vein thrombosis. CT of the abdomen confirmed portal and mid-superior mesenteric vein thromboses. Concurrent CT of the chest suggested COVID-19 infection. While reverse transcription PCR was negative, subsequent antibody serology was positive. Thrombophilia screen excluded inherited and acquired thrombophilia. Having been commenced on apixaban 5 mg two times per day, he is currently asymptomatic. This is the first case of COVID-19-related portomesenteric thrombosis described in the UK. A recent meta-analysis suggests 9.2% of COVID-19 cases develop abdominal pain. Threshold for performing abdominal imaging must be lower to avoid this reversible complication.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In cases of portal vein thrombosis, the initial location may be in the right hypochondrium, mimicking biliary colic.
“In cases of portal vein thrombosis, the initial location may be in the right hypochondrium, mimicking biliary colic [26,34].”
From Acute mesenteric ischemia in COVID-19 patients (2021) · cites this paper as [26]
30 case reports or case series presented 34 cases of acute bowel ischemia in patients positive for SARS-CoV-2 infection in different clinical settings.
“We also identified 30 case reports or case series [22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51] presenting 34 cases of acute bowel ischemia in patients positive for SARS-CoV-2 infection in different clinical settings.”
From Acute mesenteric ischemia in COVID-19 patients (2021) · cites this paper as [26]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Huang, C., Wang, Y., Li, X., Ren, L., Zhao, J., Hu, Y., Zhang, L., Fan, G., Xu, J., Gu, X., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30183-5 · Cited by 48,884 · see citing works
Tang, N., Li, D., Wang, X., & Sun, Z.-Y. (2020) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.14768 · Cited by 5,527 · see citing works
Incidence of thrombotic complications in critically ill ICU patients with COVID-19
Klok, F. A., Kruip, M. J. H. A., van der Meer, N. J. M., Arbous, M. S., Gommers, D. A. M. P. J., Kant, K. M., Kaptein, F. H. J., van Paassen, J., Stals, M. A. M., Huisman, M. V., et al. (2020) · Thrombosis Research · doi:10.1016/j.thromres.2020.04.013 · Cited by 5,028 · see citing works
Bikdeli, B., Madhavan, M. V., Jiménez, D., Chuich, T., Dreyfus, I., Driggin, E., Der-Nigoghossian, C. A., Ageno, W., Madjid, M., Guo, Y., et al. (2020) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2020.04.031 · Cited by 2,902 · see citing works
Liver injury in COVID-19: management and challenges
Zhang, C., Shi, L., & Wang, F. (2020) · The Lancet. Gastroenterology & hepatology · doi:10.1016/s2468-1253(20)30057-1 · Cited by 1,941 · see citing works
Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia
Cui, S., Chen, S., Li, X., Liu, S., & Wang, F. (2020) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.14830 · Cited by 1,805 · see citing works
Cheung, K. S., Hung, I. F. N., Chan, P. P. Y., Lung, K. C., Tso, E., Liu, R., Ng, Y. Y., Chu, M. Y., Chung, T. W. H., Tam, A. R., et al. (2020) · Gastroenterology · doi:10.1053/j.gastro.2020.03.065 · Cited by 1,631 · see citing works
COVID-19: Abnormal liver function tests
Cai, Q., Huang, D., Yu, H., Zhu, Z., Zhang, X., Su, Y., Li, Z., Zhou, G., Gou, J., Qu, J., et al. (2020) · Journal of Hepatology · doi:10.1016/j.jhep.2020.04.006 · Cited by 1,084 · see citing works
Specific ACE2 Expression in Cholangiocytes May Cause Liver Damage After 2019-nCoV Infection
Chai, X., Hu, L., Zhang, Y., Han, W., Lu, Z., Ke, A., Zhou, J., Shi, G., Fang, N., Fan, J., et al. (2020) · doi:10.1101/2020.02.03.931766 · Cited by 952 · see citing works
Systematic review: portal vein thrombosis in cirrhosis
Tsochatzis, E. A., Senzolo, M., Germani, G., Gatt, A., & Burroughs, A. K. (2009) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2009.04182.x · Cited by 284 · see citing works
Systematic review with meta‐analysis: liver manifestations and outcomes in COVID‐19
Kulkarni, A. V., Kumar, P., Tevethia, H. V., Premkumar, M., Arab, J. P., Cândia, R., Talukdar, R., Sharma, M., Qi, X., Rao, P. N., et al. (2020) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.15916 · Cited by 247 · see citing works
Arterial and venous abdominal thrombosis in a 79-year-old woman with COVID-19 pneumonia
de Barry, O., Mekki, A., Diffre, C., Seror, M., El Hajjam, M., & Carlier, R.-Y. (2020) · Radiology Case Reports · doi:10.1016/j.radcr.2020.04.055 · Cited by 102 · see citing works
Acute Portal Vein Thrombosis in SARS-CoV-2 Infection: A Case Report
Mura, V. L., Artoni, A., Martinelli, I., et al. (2020) · The American Journal of Gastroenterology · doi:10.14309/ajg.0000000000000711 · Cited by 39 · see citing works
Portal vein thrombosis in a patient with COVID-19
Franco‐Moreno, A., Piniella-Ruiz, E., Montoya-Adárraga, J., Ballano-Franco, C., Alvarez-Miguel, F., Peinado-Martinez, C., Landete, E., Saez-Vaquero, T., Ulla‐Anés, M., & Torres‐Macho, J. (2020) · Thrombosis Research · doi:10.1016/j.thromres.2020.06.019 · Cited by 38 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Acute mesenteric ischemia in COVID-19 patients
Serban, D., Tribus, L. C., Vancea, G., Stoian, A. P., Dascalu, A. M., Suceveanu, A. I., Tanasescu, C., Costea, A. C., Tudosie, M. S., Tudor, C., et al. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm11010200 · Cited by 46 · see citing works
Portal-splenic-mesenteric venous thrombosis in COVID-19 patients: a systematic review
Gomes, R. Z., Salina, M. V. J., Pironatto, V. H. M., Lepinski, J. K., Gueiber, T. D., Juliatto, B. M. S., Prestes, M. Z., & Martins, C. M. (2025) · Jornal Vascular Brasileiro · doi:10.1590/1677-5449.202301282 · Cited by 2 · see citing works
- Authors
- Abeysekera, K. W., Karteszi, H., Clark, A., & Gordon, F. H.
- Affiliations
- Bristol Royal Infirmary (GB)
- Corresponding author
- Abeysekera, Kushala WM
- Venue
- BMJ Case Reports
- Publisher
- BMJ
- Published
- 2020-12
- Volume
- 13
- Issue
- 12
- Pages
- e238906
- ISSN
- 1757-790X (ISSN-L)
- PMC
- PMC7757448
- OpenAlex
- W3117752205
- Cited by
- 22
- References
- 14
- Citations by year
- 2025: 1 · 2024: 4 · 2023: 1 · 2022: 7 · 2021: 9
- FWCI
- 0.56
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- BMJ Case Reports (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Explore Bristol Research (publishedVersion)
- Bristol Research (University of Bristol) (submittedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Health Sciences › Medicine › Surgery › Abdominal vascular conditions and treatments
- Health Sciences › Medicine › Internal Medicine › Venous Thromboembolism Diagnosis and Management
- Keywords
- COVID-19 pandemic, portal vein thrombosis, superior mesenteric vein thrombosis, chronic hepatitis B, thrombophilia screening, apixaban, abdominal pain, antibody serology
- MeSH terms
- COVID-19, SARS-CoV-2, COVID-19 Serological Testing, Adult, Diagnosis, Differential, Humans, Male, Mesenteric Veins, Portal Vein, Portography, Pyrazoles, Pyridones, Tomography, X-Ray Computed, Ultrasonography, Abdominal Pain, Treatment Outcome, Hepatitis B, Chronic, Factor Xa Inhibitors, Mesenteric Ischemia
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
