Cited by 30Ocular Infections and TreatmentsInfection Control in HealthcareMedical Device Sterilization and Disinfection

Survey of the contamination of eyedrops of hospital inpatients and recommendations for the changing of current practice in eyedrop dispensing

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Stevens, J D, Matheson, M M·1992·British Journal of Ophthalmology

Abstract

Topical ophthalmic medications used on the ward and from the outpatient area have been taken and cultured for potential bacterial contamination in the laboratory. We examined 143 bottles used by patients who had had routine cataract surgery and trabeculectomy. We also examined for bacterial contamination 216 bottles of eyedrops used in the outpatient area of the hospital. No contamination was found in the postoperative eyedrops, but five bottles were contaminated from the outpatient area (2.3%). The bacterial growth from outpatient drops was of the same order of magnitude as in previous studies. The practice in the UK for postoperative eyedrops to be discarded and fresh, separate bottles to take home is discussed. We recommend that this practice be changed so that the postoperative drops used for 72 hours or less are taken home.

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Crossref · 10.1136/bjo.76.1.36

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  • Allowing patients to use topical medications after discharge, rather than discarding unused medication, can address some drug waste issues.

    “Allowing patients to use topical medications after discharge, rather than discarding the unused medication, can address some drug waste issues.79”

    From How Ophthalmologists Can Decarbonize Eye Care (2023) · cites this paper as [79]

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Research works printed but not linked: 5

  1. [7]7. Marion AD, Tapert MJ. Bacterial contamination of timolol in use by a non-selected clinic population. ARVO Abstracts. Invest Ophthalmol Vis Sci supplement. Philadelphia: Lippincott, 1986: 36.
  2. [9]9. Hugo WB, Wilson JV. In-use contamination of eye-drops. PharmJ 1970; 204: 714.
  3. [16]16. Preservation of eye-drops. (Editorial.) Pharm J 1964; 192: 587-8.
  4. [17]17. Stewart HL. Prolonged antibacterial activity of fluorescein- anaesthetic solution. Arch Ophthalmol 1972; 88: 385-7.
  5. [19]19. Davison AL, Hooper WL, Spooner DF, Farwell JA, Baird R. The validity of the criteria of pharmacopoeial preservative efficacy tests -a pilot study. PharmJf 1991; 246: 555-7.

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Authors
Stevens, J. D., & Matheson, M. M.
Affiliations
Moorfields Eye Hospital (GB)
Venue
British Journal of Ophthalmology
Publisher
BMJ
Published
1992-01-01
Volume
76
Issue
1
Pages
36-38
ISSN
0007-1161 (ISSN-L)
OpenAlex
W2164305364
Cited by
30
References
13
Citations by year
2025: 2 · 2024: 1 · 2023: 1 · 2022: 3 · 2021: 1 · 2020: 2 · 2019: 2 · 2018: 1 · 2017: 1 · 2016: 1 · 2015: 3
FWCI
0.58
Type
journal article
Language
en
Open access
Locations
  • British Journal of Ophthalmology (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • HighWire Press Open Archive (submittedVersion)
Topics
  • Health Sciences › Medicine › Ophthalmology › Ocular Infections and Treatments
  • Health Sciences › Medicine › Infectious Diseases › Infection Control in Healthcare
  • Life Sciences › Immunology and Microbiology › Microbiology › Medical Device Sterilization and Disinfection
Keywords
bacterial contamination, hospitalized patients, cataract surgery, trabeculectomy
MeSH terms
Cataract Extraction, Drug Contamination, Hospitalization, Humans, Length of Stay, Ophthalmic Solutions, Outpatient Clinics, Hospital, Postoperative Care, Time Factors, Trabeculectomy

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