Protection of mice against the lethal action of an encephalitis virus
Open accessThe claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
After the discovery of IFN-α, it became clear that this cytokine can influence immunological processes in the brain even when peripherally administered and can be produced by cells within the brain.
“Shortly after the discovery of the first cytokine, IFN-α (12), it became clear that this cytokine was able to influence immunological processes in the brain even when peripherally administered (17, 18) and that it can be produced by cells within the brain (18).”
From Cytokine Research in Depression: Principles, Challenges, and Open Questions (2019) · cites this paper as [17]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Isaacs, A., & Burke, D. C. (1958) · Nature · doi:10.1038/1821073a0 · Cited by 117 · see citing works
Self-citationSTUDIES ON PERSISTENT INFECTIONS OF TISSUE CULTURES
Henle, W., Henle, G., Deinhardt, F. W., & Bergs, V. V. (1959) · The Journal of Experimental Medicine · doi:10.1084/jem.110.4.525 · Cited by 109 · see citing works
AN INHIBITOR OF VIRAL ACTIVITY APPEARING IN INFECTED CELL CULTURES
Ho, M., & Enders, J. F. (1959) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.45.3.385 · Cited by 94 · see citing works
INHIBITION BY INTERFERON OF THE GROWTH OF VACCINIA VIRUS IN THE RABBIT SKIN
Isaacs, A., & Westwood, M. (1959) · The Lancet · doi:10.1016/s0140-6736(59)91361-3 · Cited by 67 · see citing works
Self-citationSTUDIES ON RECOMBINATION WITH INFLUENZA VIRUSES IN THE CHICK EMBRYO
Burnet, F. M., & Fraser, K. B. (1952) · Immunology and Cell Biology · doi:10.1038/icb.1952.44 · Cited by 13 · see citing works
Flagged first, then by citations
Research works printed but not linked: 3
- Grossberg, S., Hook, E. W., and Wagner, R. R. (1960). Fed. Proc., 19, 408.
- Ho, M., and Enders, J. F. (1959). Proc. nat. Acad. Sci. (Wash.), 45, 385.
- and Lindenmann, J. (1957). Proc. roy. Soc. B., 147, 258.
Cited by
Sorted by citations
Cytokine Research in Depression: Principles, Challenges, and Open Questions
Himmerich, H., Patsalos, O., Lichtblau, N., Ibrahim, M. A. A., & Dalton, B. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00030 · Cited by 313 · see citing works
Circulating Interferon in Mice after Intravenous Injection of Virus
Baron, S., & Buckler, C. E. (1963) · Science · doi:10.1126/science.141.3585.1061 · Cited by 158 · see citing works
Peters, C. J., Reynolds, J. A., SLONE, T. W., Jones, D., & Stephen, E. L. (1986) · Antiviral Research · doi:10.1016/0166-3542(86)90024-0 · Cited by 144 · see citing works
Bowden, D. H. (1984) · Environmental Health Perspectives · doi:10.1289/ehp.8455327 · Cited by 108 · see citing works
GENETIC FACTORS IN RESISTANCE TO MALARIA
ALLISON, A. C. (1961) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1961.tb31102.x · Cited by 107 · see citing works
Mechanism of Recovery from Viral Infection
Baron, S. (1964) · Advances in virus research · doi:10.1016/s0065-3527(08)60696-x · Cited by 88 · see citing works
Isaacs, A. (1964) · Advances in virus research · doi:10.1016/s0065-3527(08)60695-8 · Cited by 64 · see citing works
Self-citationProduction of Interferon by Alveolar Macrophages
Acton, J. D., & Myrvik, Q. N. (1966) · Journal of Bacteriology · doi:10.1128/jb.91.6.2300-2304.1966 · Cited by 63 · see citing works
Mechanism of Recovery from Viral Infection in the Chick Embryo
Baron, S., & Isaacs, A. (1961) · Nature · doi:10.1038/191097a0 · Cited by 52 · see citing works
Self-citationThe Biological Significance of the Interferon System
Baron, S. (1970) · Archives of Internal Medicine · doi:10.1001/archinte.126.1.84 · Cited by 48 · see citing works
Ho, M. (1962) · New England Journal of Medicine · doi:10.1056/nejm196206142662406 · Cited by 48 · see citing works
Bowden, D. H. (1971) · Springer eBooks · doi:10.1007/978-3-642-65208-0_1 · Cited by 37 · see citing works
The Effect of Interferon and Interferon Inducers on Avian Influenza
Portnoy, J., & Merigan, T. C. (1971) · The Journal of Infectious Diseases · doi:10.1093/infdis/124.6.545 · Cited by 34 · see citing works
Factors in the Pathogenesis of Virus Diseases
Bang, F. B., & Luttrell, C. N. (1962) · Advances in virus research · doi:10.1016/s0065-3527(08)60686-7 · Cited by 33 · see citing works
Interferon in prospect and perspective
Hilleman, M. R. (1963) · Journal of Cellular and Comparative Physiology · doi:10.1002/jcp.1030620314 · Cited by 32 · see citing works
CELLULAR RESISTANCE TO VIRAL INFECTION, WITH PARTICULAR REFERENCE TO ENDOGENOUS INTERFERON
Wagner, R. R. (1963) · Bacteriological Reviews · doi:10.1128/br.27.1.72-86.1963 · Cited by 30 · see citing works
Clercq, E. D., & Somer, P. D. (1968) · Life Sciences · doi:10.1016/0024-3205(68)90098-2 · Cited by 28 · see citing works
Andrews, R. D. (1961) · BMJ · doi:10.1136/bmj.1.5241.1728 · Cited by 28 · see citing works
Studies on mechanisms of arthropod-borne virus interference in tissue culture
Henderson, J. R., & Taylor, R. M. (1961) · Virology · doi:10.1016/0042-6822(61)90278-1 · Cited by 21 · see citing works
Exogenous Interferon in Animals and Its Clinical Implications
Finter, N. B. (1970) · Archives of Internal Medicine · doi:10.1001/archinte.126.1.147 · Cited by 21 · see citing works
POSSIBLE ROLE OF INTERFERON IN DETERMINING THE ONCOGENIC EFFECT OF POLYOMA VIRUS VARIANTS
Friedman, R. M., & Rabson, A. S. (1964) · The Journal of Experimental Medicine · doi:10.1084/jem.119.1.71 · Cited by 19 · see citing works
Sehgal, P. B., Pfeffer, L. M., & Tamm, I. (1982) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-68487-6_6 · Cited by 15 · see citing works
HAAHR, S. (1968) · Acta Pathologica Microbiologica Scandinavica · doi:10.1111/j.1699-0463.1968.tb03498.x · Cited by 15 · see citing works
PROTECTIVE EFFECT OF INTERFERON IN RATS INFECTED WITH SINDBIS VIRUS
Denys, P. (1963) · The Lancet · doi:10.1016/s0140-6736(63)92806-x · Cited by 15 · see citing works
Chemoprophylaxis and Chemotherapy of Viral Diseases
Thompson, R. L. (1964) · Elsevier eBooks · doi:10.1016/b978-1-4831-9929-0.50009-7 · Cited by 15 · see citing works
Evaluation of interferon and interferon inducers as antiviral agents: Animal studies
Kern, E. R., & Glasgow, L. A. (1981) · Pharmacology & Therapeutics · doi:10.1016/0163-7258(81)90065-6 · Cited by 14 · see citing works
The Defensive Role of the Interferon System
Baron, S. (1970) · The Journal of General Physiology · doi:10.1085/jgp.56.1.193 · Cited by 13 · see citing works
Antiviral activities of interferons
Stewart, W. E., & Lin, L. S. (1979) · Pharmacology & Therapeutics · doi:10.1016/0163-7258(79)90063-9 · Cited by 13 · see citing works
Die Interferenz zwischen dem Polyoma-Virus und dem Stomatitis-vesicularis-Virus in der Maus
Falke, D., & Rowe, W. P. (1965) · Archives of Virology · doi:10.1007/bf01257732 · Cited by 6 · see citing works
Influence of Statolon on Resistance of Mice to Influenza
Pindak, F. F., Schmidt, J. P., & Kendrick, J. Z. (1969) · Applied Microbiology · doi:10.1128/aem.18.2.147-151.1969 · Cited by 5 · see citing works
Protective effect of interferon in influenza-infected mice
Denys, P., Somer, P. D., & Prinzie, A. (1961) · Antonie van Leeuwenhoek · doi:10.1007/bf02538452 · Cited by 4 · see citing works
Garell, D. C. (1963) · American journal of diseases of children · doi:10.1001/archpedi.1963.02080040108019 · Cited by 3 · see citing works
Virus und Virusinfektionen, eine Einführung in die Grundlagen
Poetschke, G., & Klamerth, O. L. (1965) · Handbuch der allgemeinen Pathologie · doi:10.1007/978-3-642-85739-3_5 · Cited by 3 · see citing works
Basic Science Review : Interferon
Paucker, K. (1964) · Clinical Pediatrics · doi:10.1177/000992286400301112 · Cited by 2 · see citing works
Subrahmanyan, T. P., & Mims, C. A. (1967) · PubMed Central · Cited by 2 · see citing works
Watkins, J., & LEPOW, M. L. (1963) · PubMed Central · Cited by 1 · see citing works
Arbor-Viren (durch Arthropoden übertragbare Viren)
Haagen, E. (1964) · Steinkopff eBooks · doi:10.1007/978-3-642-85280-0_5 · Cited by 1 · see citing works
ANDREWS, R. D. (1970) · Elsevier eBooks · doi:10.1016/b978-0-433-00651-0.50009-1
Prospects for a Viral Antibiotic
(1961) · The Lancet · doi:10.1016/s0140-6736(61)92197-3
Piet De Somer (1917–85): a scientific career
Clercq, E. D. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-33885-4.00017-2
- Authors
- Hitchcock, G., & Isaacs, A.
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 1960-10-29
- Volume
- 2
- Issue
- 5208
- Pages
- 1268-1270
- ISSN
- 0007-1447 (ISSN-L)
- 0959-8138
- 1468-5833
- PMC
- PMC2097058
- OpenAlex
- W2049761087
- Cited by
- 40
- References
- 5
- Citations by year
- 2025: 1 · 2019: 1
- FWCI
- 14.12
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- BMJ (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Virology and Viral Diseases
- Health Sciences › Medicine › Infectious Diseases › Infectious Encephalopathies and Encephalitis
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Viral Infections and Immunology Research
- Keywords
- encephalitis virus, viral encephalitis, mouse protection, antiviral immunity, lethal viral infection
- MeSH terms
- Animals, Encephalitis, Encephalitis Viruses, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review