The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Reduced dopamine-beta-hydroxylase activity in Alzheimer's disease
Open accessAbstract
The activity of the noradrenergic marker enzyme dopamine-beta-hydroxylase was measured in brains removed postmortem from control patients and patients with Alzheimer's disease. Enzyme activity was decreased in the frontal and temporal cortices and hippocampus in patients with Alzheimer's disease, but was within the normal range in patients with depression, multiinfarct dementia, and terminal coma. The decrease in enzyme activity in Alzheimer's disease may reflect an abnormality of cortical noradrenergic fibres in some patients with the disease.
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Citations
Cites
Observations on the brains of demented old people
Tomlinson, B. E., Blessed, G., & Roth, M. (1970) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(70)90063-8 · Cited by 2,084
Self-citation
Cited by
Bartus, R. T. (2000) · Experimental Neurology · doi:10.1006/exnr.2000.7397 · Cited by 829
Katzman, R. (1986) · New England Journal of Medicine · doi:10.1056/nejm198604103141506 · Cited by 801
Neurochemical characteristics of early and late onset types of Alzheimer's disease.
Rossor, M. N., Iversen, L. L., Reynolds, G. P., Mountjoy, C. Q., & Roth, M. (1984) · BMJ · doi:10.1136/bmj.288.6422.961 · Cited by 417
The neurobiologie consequences of down syndrome
Coyle, J. T., Oster-Granite, M. L., & Gearhart, J. D. (1986) · Brain Research Bulletin · doi:10.1016/0361-9230(86)90074-2 · Cited by 248
Neuron loss in key cholinergic and aminergic nuclei in Alzheimer disease: a meta-analysis
Lyness, S. (2003) · Neurobiology of Aging · doi:10.1016/s0197-4580(02)00057-x · Cited by 240
Metadata
- Authors
- Cross, A. J., Crow, T. J., Perry, E. K., Perry, R. H., Blessed, G., & Tomlinson, B. E.
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 1981-01-10
- Volume
- 282
- Issue
- 6258
- Pages
- 93-94
- ISSN
- 0007-1447 (ISSN-L)
- 0267-0623
- 1468-5833
- OpenAlex
- W1971794055
- Cited by
- 267
- References
- 1
- FWCI
- 21.78
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Cross, A. J., Crow, T. J., Perry, E. K., Perry, R. H., Blessed, G., & Tomlinson, B. E. (1981). Reduced dopamine-beta-hydroxylase activity in Alzheimer's disease. BMJ. https://doi.org/10.1136/bmj.282.6258.93
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
