Leucocytoclastic vasculitis and pneumonitis induced by metformin.
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hormone this may help to explain the association of cigarette smoking with various menstrual disorders, including an early menopause.2Thus smoking may have hormonal effects due, at least partly, to an increased release of dopamine.I Baron JA.Cigarette smoking and Parkinson's Disease.Neuroloy 4NY) (in press).2 Andersson K, Fuxe K, Eneroth P, Mascagni F, Agnati LF.Effects of acute intermittent exposure to cigarette smoke on catecholamine levels and turnover in various types of hypothalamic DA and NA nerve terminal systems as well as on the secretion of adenohypophvseal hormones and corticosterone. .
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Other adverse reactions of metformin are sporadic, such as leucocytoclastic vasculitis, allergic pneumonitis, cholestatic jaundice, and hemolytic anaemia.
“Other adverse reactions are sporadic, such as leucocytoclastic vasculitis, allergic pneumonitis [170], cholestatic jaundice [171], and hemolytic anaemia [172].”
From Metformin: An Old But Still the Best Treatment for Type 2 Diabetes (2013) · cites this paper as [170]
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Metformin: An Old But Still the Best Treatment for Type 2 Diabetes
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“Other adverse reactions are sporadic, such as leucocytoclastic vasculitis, allergic pneumonitis [170], cholestatic jaundice [171], and hemolytic anaemia [172].”
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“[173,174]”
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“[10] The second case was a 33-year-old female patient using metformin 850 mg/day to lose weight.”
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- Authors
- Klapholz, L., Leitersdorf, E., & Weinrauch, L.
- Affiliations
- Dartmouth College (US)
- ORCID
- Leitersdorf, E
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 1986-08-23
- Volume
- 293
- Issue
- 6545
- Pages
- 483-483
- ISSN
- 0007-1447 (ISSN-L)
- 0959-8138
- 1468-5833
- OpenAlex
- W2083208329
- Cited by
- 34
- References
- 0
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 1 · 2023: 1 · 2022: 1 · 2019: 2 · 2016: 3 · 2015: 1 · 2014: 1 · 2013: 2
- FWCI
- 2.00
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- BMJ (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Pharmacovigilance and Adverse Drug Reactions
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Vasculitis and related conditions
- Health Sciences › Medicine › Pharmacology › Drug-Induced Adverse Reactions
- Keywords
- metformin, drug-induced vasculitis, leukocytoclastic vasculitis, pneumonitis, adverse drug reactions, cigarette smoking, dopamine, menopause
- MeSH terms
- Female, Humans, Metformin, Middle Aged, Pulmonary Fibrosis, Vasculitis, Leukocytoclastic, Cutaneous
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