The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Resistance to Suppression by Dexamethasone of Plasma 11-O.H.C.S. Levels in Severe Depressive Illness
Open accessAbstract
Use of the midnight dexamethasone suppression test showed that the plasma 11-hydroxycorticosteroid (11-O.H.C.S.) level did not undergo its normal reduction in 14 out of 27 patients with severe depression. Resistance to dexamethasone suppression correlated with the clinical rating of the severity of depression, while recovery from depression was associated with return of normal responsiveness to dexamethasone. The explanation of these findings is unknown.
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“The first test to detect HPA axis alterations was the dexamethasone suppression test (DST), which identifies an insufficient suppression of cortisol following dexamethasone intake [48].”
From The HPA Axis as Target for Depression (2024) · cites this paper as [48]
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Citations
Cites
The Biochemistry of Affective Disorders
Coppen, A. (1967) · British Journal of Psychiatry · doi:10.1192/bjp.113.504.1237 · Cited by 1,230
A simple fluorimetric method for the estimation of free 11-hydroxycorticoids in human plasma
Mattingly, D. (1962) · Journal of Clinical Pathology · doi:10.1136/jcp.15.4.374 · Cited by 1,181
Diagnosis of Cushing's Syndrome
Nugent, C. A. (1965) · Archives of Internal Medicine · doi:10.1001/archinte.1965.03870020012006 · Cited by 202
Plasma Cortisol Levels in Depression
Doig, R. J., Mummery, R. V., WILLS, M. R., & Elkes, A. (1966) · The British Journal of Psychiatry · doi:10.1192/bjp.112.493.1263 · Cited by 86
Pituitary Adrenal Function and Depression
FAWCETT, J. A. (1967) · Archives of General Psychiatry · doi:10.1001/archpsyc.1967.01730230001001 · Cited by 78
Circadian Pattern of Plasma 17-Hydroxycorticosteroid: Alteration by Anticholinergic Agents
Krieger, D. T., & Krieger, H. P. (1967) · Science · doi:10.1126/science.155.3768.1421 · Cited by 68
Plasma II-Hydroxycorticosteroids in Affective Disorders
Brooksbank, B. W. L., & Coppen, A. J. (1967) · The British Journal of Psychiatry · doi:10.1192/bjp.113.497.395 · Cited by 60
Diagnosis of Cushing's syndrome.
Hough, F. S. (1996) · PubMed · Cited by 58
Singledose dexamethasone suppression test for Cushing's Syndrome.
McHardy-Young, S., Harris, P. W. R., Lessof, M. H., & Lyne, C. (1967) · BMJ · doi:10.1136/bmj.2.5554.740 · Cited by 49
Stenhouse, A. C. (1968) · BMJ · doi:10.1136/bmj.3.5613.287 · Cited by 34
Cited by
Sorted by citations
Carroll, B. J. (1981) · Archives of General Psychiatry · doi:10.1001/archpsyc.1981.01780260017001 · Cited by 2,243
Self-citationAdult hippocampal neurogenesis in depression
Sahay, A., & Hen, R. (2007) · Nature Neuroscience · doi:10.1038/nn1969 · Cited by 1,206
Mood disorders and allostatic load
McEwen, B. S. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00177-x · Cited by 1,135
The Dexamethasone Suppression Test for Melancholia
Carroll, B. J. (1982) · The British Journal of Psychiatry · doi:10.1192/bjp.140.3.292 · Cited by 770
Self-citationA users guide to HPA axis research
Spencer, R. L., & Deak, T. (2016) · Physiology & Behavior · doi:10.1016/j.physbeh.2016.11.014 · Cited by 454
Metadata
- Authors
- Carroll, B. J., Martin, F. I. R., & Davies, B.
- Affiliations
- The Royal Melbourne Hospital (AU)
- ORCID
- Carroll, B. J.
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 1968-08-03
- Volume
- 3
- Issue
- 5613
- Pages
- 285-287
- ISSN
- 0007-1447 (ISSN-L)
- 1468-5833
- PMC
- PMC1986248
- OpenAlex
- W2055891857
- Cited by
- 279
- References
- 10
- Citations by year
- 2026: 1 · 2024: 4 · 2023: 4 · 2022: 4 · 2021: 4 · 2020: 7 · 2019: 4 · 2018: 4 · 2017: 5 · 2016: 4 · 2015: 7 · 2014: 4 · 2013: 14 · 2012: 5
- FWCI
- 5.84
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.bmj.com/company/legal-information/terms-conditions/legal-information/tdm-licencepolicy (tdm)
- Locations
- BMJ (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- HighWire Press Open Archive (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Keywords
- dexamethasone suppression test, 11-hydroxycorticosteroids, plasma corticosteroid levels, depression, severe depression, hypothalamic-pituitary-adrenal axis, depression severity, recovery from depression, glucocorticoid resistance
- MeSH terms
- Adolescent, Adult, Aged, Anorexia Nervosa, Anxiety, Circadian Rhythm, Depression, Dexamethasone, Fatigue, Mental Fatigue, Female, Fluorometry, Glucocorticoids, Humans, Male, Middle Aged, Pituitary-Adrenal Function Tests, Time Factors
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