The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.
Predictors for the development of microalbuminuria and macroalbuminuria in patients with type 1 diabetes: inception cohort study
Open accessAbstract
OBJECTIVE: To evaluate baseline predictors for the development of persistent microalbuminuria and macroalbuminuria prospectively in patients with type 1 diabetes. DESIGN: Prospective observational study of an inception cohort. SETTING: Outpatient diabetic clinic in a tertiary referral centre, Gentofte, Denmark. PARTICIPANTS: 286 patients (216 adults) newly diagnosed with type 1 diabetes consecutively admitted to the clinic between 1 September 1979 and 31 August 1984. MAIN OUTCOME MEASURES: Persistent microalbuminuria and persistent macroalbuminuria. RESULTS: During the median follow up of 18.0 years (range 1.0-21.5 years), total of 4706 patient years of follow up, 79 of 277 (29%) patients developed persistent microalbuminuria. 27 of 79 progressed further to persistent macroalbuminuria. The cumulative incidence of persistent microalbuminuria and persistent macroalbuminuria was 33.6% (95% confidence interval 27.2% to 40.0%) and 14.6% (8.9% to 20.3%), respectively. Significant predictors for the development of persistent microalbuminuria were a 10-fold increase in urinary albumin excretion rate (relative risk 3.78, 1.57 to 9.13), being male (2.41, 1.43 to 4.06), a 10 mm Hg increase in mean arterial blood pressure (1.38, 1.20 to 1.57), a 1% increase in haemoglobin A1c (1.18, 1.04 to 1.32), and a 1 cm increase in height (0.96, 0.95 to 0.98). 28 patients with microalbuminuria (35%) regressed to normoalbuminuria either transiently (n = 15) or permanently (n = 13). CONCLUSIONS: Around one third of patients newly diagnosed with type 1 diabetes develop persistent microalbuminuria within the first 20 years of diabetes. Several potentially modifiable risk factors predict the development of persistent microalbuminaria and persistent macroalbuminuria.
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The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes
Parving, H.-H., Lehnert, H., Bröchner-Mortensen, J., Gomis, R., Andersen, S., & Arner, P. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa011489 · Cited by 2,873
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Parving, H., Lehnert, H., Brøchner‐Mortensen, J., Gomis, R., Andersen, S., & Arner, P. (2001) · PubMed · Cited by 2,527
Self-citationMICROALBUMINURIA AS A PREDICTOR OF CLINICAL NEPHROPATHY IN INSULIN-DEPENDENT DIABETES MELLITUS
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Regression of Microalbuminuria in Type 1 Diabetes
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Diabetic nephropathy: diagnosis, prevention, and treatment
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Katsarou, A., Gudbjörnsdottir, S., Rawshani, A., Dabelea, D., Bonifacio, E., Anderson, B. J., Jacobsen, L. M., Schatz, D. A., & Lernmark, Å. (2017) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2017.16 · Cited by 1,475
KDOQI clinical practice guideline for diabetes and CKD: 2012 update
(2012) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2012.07.005 · Cited by 1,320
Risk Factors for Renal Dysfunction in Type 2 Diabetes
Retnakaran, R., Cull, C. A., Thorne, K. I., Adler, A. I., Holman, R. R., & for the UKPDS Study Group (2006) · Diabetes · doi:10.2337/db05-1620 · Cited by 927
The Early Natural History of Nephropathy in Type 1 Diabetes
Steinke, J. M., Sinaiko, A. R., Kramer, M. S., Suissa, S., Chavers, B. M., Mauer, M., & for the International Diabetic Nephropathy Study Group (2005) · Diabetes · doi:10.2337/diabetes.54.7.2164 · Cited by 190
Metadata
- Authors
- Hovind, P., Tarnow, L., Rossing, P., Graae, M., Torp, I., Binder, C., & Parving, H.-H.
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 2004-04-19
- Volume
- 328
- Issue
- 7448
- Pages
- 1105
- ISSN
- 0007-1447 (ISSN-L)
- 0959-8138
- 1468-5833
- OpenAlex
- W2131365513
- Cited by
- 432
- References
- 34
- FWCI
- 11.02
- Type
- journal article
- Language
- en
- Open access
- bronze
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