Cited by 1,171Diabetes Treatment and ManagementDiabetes, Cardiovascular Risks, and LipoproteinsPharmacology and Obesity Treatment

The DOI matches its Crossref record; 40 of the 43 references it cites were found in a registry or an index.

Pharmacological and lifestyle interventions to prevent or delay type 2 diabetes in people with impaired glucose tolerance: systematic review and meta-analysis

Open access

Gillies, Clare L, Abrams, Keith R, Lambert, Paul C, Cooper, Nicola J, Sutton, Alex J, Hsu, Ron T, Khunti, Kamlesh·2007·BMJ

DOI 10.1136/bmj.39063.689375.55PMC PMC1796695

Open this paper in CoChat — free account Open PDF

Abstract

OBJECTIVE: To quantify the effectiveness of pharmacological and lifestyle interventions to prevent or delay type 2 diabetes in people with impaired glucose tolerance. DATA SOURCES: Medline, Embase, and the Cochrane library searched up to July 2006. Expert opinions sought and reference lists of identified studies and any relevant published reviews checked. STUDY SELECTION: Randomised controlled trials that evaluated interventions to delay or prevent type 2 diabetes in individuals with impaired glucose tolerance. RESULTS: 21 trials met the inclusion criteria, of which 17, with 8084 participants with impaired glucose tolerance, reported results in enough detail for inclusion in the meta-analyses. From the meta-analyses the pooled hazard ratios were 0.51 (95% confidence interval 0.44 to 0.60) for lifestyle interventions v standard advice, 0.70 (0.62 to 0.79) for oral diabetes drugs v control, 0.44 (0.28 to 0.69) for orlistat v control, and 0.32 (0.03 to 3.07) for the herbal remedy jiangtang bushen recipe v standard diabetes advice. These correspond to numbers needed to treat for benefit (NNTB) and harm (NNTH) of 6.4 for lifestyle (95% credible interval, NNTB 5.0 to NNTB 8.4), 10.8 for oral diabetes drugs (NNTB 8.1 to NNTB 15.0), 5.4 for orlistat (NNTB 4.1 to NNTB 7.6), and 4.0 for jiangtang bushen (NNTH 16.9 to NNTB 24.8). CONCLUSIONS: Lifestyle and pharmacological interventions reduce the rate of progression to type 2 diabetes in people with impaired glucose tolerance. Lifestyle interventions seem to be at least as effective as drug treatment.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1136/bmj.39063.689375.55

Cites

40 of 40 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Measuring inconsistency in meta-analyses
Higgins, J. P. T., Thompson, S. G., Deeks, J. J., & Altman, D. G. (2003) · BMJ · doi:10.1136/bmj.327.7414.557 · Cited by 63,139
Assessing the quality of reports of randomized clinical trials: Is blinding necessary?
Jadad, A. R., Moore, R. A., Carroll, D., Jenkinson, C., Reynolds, D. J. M., Gavaghan, D. J., & McQuay, H. J. (1996) · Controlled Clinical Trials · doi:10.1016/0197-2456(95)00134-4 · Cited by 17,582
Global Prevalence of Diabetes
Wild, S., Roglic, G., Green, A., Sicree, R., & King, H. (2004) · Diabetes Care · doi:10.2337/diacare.27.5.1047 · Cited by 15,297
Aspirin plus Clopidogrel as Secondary Prevention after Stroke or Transient Ischemic Attack: A Systematic Review and Meta-Analysis
Zhang, Q., Wang, C., Zheng, M., Li, Y., Li, J., Zhang, L., Shang, X., & Yan, C. (2014) · Cerebrovascular Diseases · doi:10.1159/000369778 · Cited by 11,609
Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus
The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus* (2002) · Diabetes Care · doi:10.2337/diacare.25.2007.s5 · Cited by 10,325
Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus
The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus (1997) · Diabetes Care · doi:10.2337/diacare.20.7.1183 · Cited by 6,220
Cochrane Handbook for Systematic Reviews of Interventions
Higgins, J. P. T., Green, S., & Ben Van Den, A. (2020) · International Coaching Psychology Review · doi:10.53841/bpsicpr.2020.15.2.123 · Cited by 5,670
Efficacy and Safety of Tadalafil Monotherapy for Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia: A Meta-Analysis
Dong, Y., Hao, L., Shi, Z., Wang, G., Zhang, Z., & Han, C. (2013) · Urologia Internationalis · doi:10.1159/000351405 · Cited by 4,557
Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints.
Parmar, M. K. B., Torri, V., & Stewart, L. (1998) · Statistics in Medicine · doi:10.1002/(sici)1097-0258(19981230)17:24 · Cited by 4,519
Untitled work
(2000) · Queen Mary Research Online (Queen Mary University of London) · Cited by 1,795
Self-citation

Flagged first, then by citations

Show all 43 references

3 of the 43 references couldn’t be matched to a known paper.

Research works printed but not linked: 3

[4]4. Angelo JB, Huang J, Carden D. Diabetes prevention: a review of current literature. Adv Stud Med 2005;5:250-9.
[19]19. World Health Organization Expert Committee. Diabetes mellitus, second report. World Health Organ Tech Rep Ser 1980;646:1-80.
[20]20. WHO Study Group. Diabetes mellitus. World Health Organ Tech Rep Ser 1985;727:1-113.

Sorted by citations

Items 701–800 of 1,000

Insulin-sensitising drugs for polycystic ovary syndrome
Tang, T. H., Lord, J. M., Norman, R. J., Yasmin, E., & Balen, A. H. (2009) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003053.pub2 · Cited by 9
Metformin’s Overall Effectiveness and Combined Action with Lifestyle Interventions in Preventing Type-2 Diabetes Mellitus in High-Risk Metformin-Naïve Patients: An Updated Systematic Review and Meta-Analysis of Published RCTs
Tsironikos, G. I., Tsolaki, V., Zakynthinos, G. Ε., Rammou, V., Kyprianidou, D., Antonogiannis, T., Zakynthinos, E. G., & Bargiota, Α. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14144947 · Cited by 9
Common Pancreatic Disease
Leung, P. S. (2010) · Advances in experimental medicine and biology · doi:10.1007/978-90-481-9060-7_3 · Cited by 8
Sex differences in factors associated with prediabetes in Korean adults
Ra, J. S. (2022) · Osong Public Health and Research Perspectives · doi:10.24171/j.phrp.2022.0053 · Cited by 8
Knowledge, attitude, and practice regarding lifestyle modification among type 2 diabetes patients with cardiovascular disease at a Tertiary Hospital in Somalia
Mohamud, M. F. Y., & Jeele, M. O. O. (2022) · Annals of Medicine and Surgery · doi:10.1016/j.amsu.2022.103883 · Cited by 8
Bariatric Surgery for Weight Loss and Glycemic Control in Nonmorbidly Obese Adults with Diabetes
Gibbons, M. M., Maglione, M., Livhits, M. J., Ewing, B. A., Ruelaz, A. R., Hu, J., Li, Z., & Shekelle, P. (2013) · Cited by 8
Oral Glucose Tolerance Test should Be Performed after Stroke and Transient Ischemic Attack
Lindsberg, P. J., Tuomilehto, J., & Kaste, M. (2011) · International Journal of Stroke · doi:10.1111/j.1747-4949.2011.00619.x · Cited by 8
Should the first degree relatives of type 2 diabetic patients with isolated impaired fasting glucose be considered for a diabetes primary prevention program?
Iraj, B., Taheri, N., Amini, M., Amini, P., & Aminorroaya, A. (2010) · Europe PMC (PubMed Central) · Cited by 8
Knowledge of hypoglycemia and its associated risk factors among type 2 diabetes Mellitus patients in diabetes Centre, Security Forces Hospital, Riyadh, Saudi Arabia
Resident, F. M., & Albaqami, N. M. (2018) · Journal of Medical Science And clinical Research · doi:10.18535/jmscr/v6i10.01 · Cited by 8
A Double-Blind Randomized Placebo-Controlled Study Assessing the Safety, Tolerability and Efficacy of a Herbal Medicine Containing Pycnogenol Combined with Papain and Aloe vera in the Prevention and Management of Pre-Diabetes
Vitetta, L., Butcher, B., Forno, S. D., Vitetta, G., Nikov, T., Hall, S., & Steels, E. (2020) · Medicines · doi:10.3390/medicines7040022 · Cited by 9
One elevated oral glucose tolerance test value in pregnancy increases the risk for future diabetes mellitus type 2
Yefet, E., Schwartz, N., Sliman, B., & Nachum, Z. (2020) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-020-05827-5 · Cited by 8
Anti-Obesity Effect of α-Cubebenol Isolated from Schisandra chinensis in 3T3-L1 Adipocytes
Lee, S. J., Kim, J. E., Choi, Y. J., Gong, J. E., Jin, Y. J., Lee, D. W., Choi, Y. W., & Hwang, D. Y. (2021) · Biomolecules · doi:10.3390/biom11111650 · Cited by 8
Joint impact of BMI, physical activity and diet on type 2 diabetes: Findings from two population‐based cohorts in China
Shen, Q., Li, H., Li, Z., Jiang, Y., Ji, X., Tan, Y., & Xiang, Y. (2021) · Diabetic Medicine · doi:10.1111/dme.14762 · Cited by 8
We have the evidence, we need to act to improve diabetes care
Prato, S. D., Horton, E. S., Nesto, R. W., & Management, O. B. O. T. G. P. F. E. D. (2007) · International Journal of Clinical Practice · doi:10.1111/j.1742-1241.2007.01609.x · Cited by 8
Wytyczne ESC dotyczące cukrzycy, stanu przedcukrzycowego i chorób układu sercowo- -naczyniowego opracowane we współpracy z EASD
EASD, E. (2013) · Kardiologia Polska · doi:10.5603/kp.2013.0289 · Cited by 9
Implementation of Resources to Support Patient Physical Activity Through Diabetes Centres in Atlantic Canada: The Effectiveness of Toolkit-Based Physical Activity Counselling
Fowles, J. R., Shields, C. A., Barron, B. J., McQuaid, S., & Dunbar, P. (2014) · Canadian Journal of Diabetes · doi:10.1016/j.jcjd.2014.02.020 · Cited by 8
Changes in diet, cardiovascular risk factors and modelled cardiovascular risk following diagnosis of diabetes: 1‐year results from the ADDITION ‐Cambridge trial cohort
Savory, L. A., Griffin, S. J., Williams, K. M., Prevost, A. T., Kinmonth, A. L., Wareham, N. J., & Simmons, R. K. (2013) · Diabetic Medicine · doi:10.1111/dme.12316 · Cited by 8
A qualitative assessment of using lay trainers with type 2 diabetes in an intervention programme for people at risk of type 2 diabetes
Scarpello, T. J., Murray, N. J., Maisey, S., Howe, A. C., Sampson, M., & on behalf of the UEA-IFG Study Group (2012) · Health Education Journal · doi:10.1177/0017896911430562 · Cited by 8
Frequency of Food Consumption and Self-reported Diabetes among Adult Men and Women in India: A Large Scale Nationally Representative Crosssectional Study
Agrawal, S. (2015) · Journal of Diabetes & Metabolism · doi:10.4172/2155-6156.1000474 · Cited by 8
Cardiovascular Disease in Women
Sanghavi, M., & Gulati, M. (2016) · Obstetrics and Gynecology Clinics of North America · doi:10.1016/j.ogc.2016.01.001 · Cited by 9
Scaling Up Diabetes Prevention Programs in North Carolina: Perceptions of Demand From Potential Program Recipients and Providers
Thomas, T., Samuel‐Hodge, C. D., Porterfield, D. S., Alva, M. L., & Leeman, J. (2018) · The Science of Diabetes Self-Management and Care · doi:10.1177/0145721718811564 · Cited by 8
Screening for Diabetes and Prediabetes
Gray, L. J., Willis, A. M., Webb, D. R., Davies, M. J., & Khunti, K. (2018) · Endocrinology · doi:10.1007/978-3-319-45015-5_12 · Cited by 9
Self-citation
Traditional Chinese Patent Medicine for Treating Impaired Glucose Tolerance: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Pang, B., Ni, Q., Lin, Y.-Q., Wang, Y., Zheng, Y., Zhao, X., Feng, S., & Tong, X. (2018) · The Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2017.0302 · Cited by 8
Diabetes experts' reasoning about diabetes prevention studies: a questionnaire survey
Mühlhauser, I. (2008) · BMC Research Notes · doi:10.1186/1756-0500-1-90 · Cited by 9
Facilitators and barriers to implementing the Diabetes Prevention Program in rural church settings: A qualitative study using the Consolidated Framework for Implementation Research
Rawal, S., Snead, C. A., Soiro, F. D., Lawrence, J., Rivers, B. M., & Young, H. N. (2025) · The Journal of Rural Health · doi:10.1111/jrh.12888 · Cited by 7
The predictive significance of lipid accumulation products for future diabetes in a non-diabetic population from a gender perspective: an analysis using time-dependent receiver operating characteristics
Qiu, J., Kuang, M., Zou, Y., Yang, R., Shangguan, Q., Liu, D., Sheng, G., & Wang, W. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1285637 · Cited by 7
Handgrip strength and risks of diabetic vascular complications: Evidence from Guangzhou Diabetic Eye Study and UK cohorts
Zhong, P., Yang, S., Liu, R., Zhu, Z., Zhang, Y., Cheng, W., & Wang, W. (2024) · British Journal of Ophthalmology · doi:10.1136/bjo-2023-324893 · Cited by 7
Independent and Combined Associations of Physical Activity in Different Domains and Inflammatory Diet with Type 2 Diabetes: A Population-Based Cohort Study
Zhou, J., Yin, S., Du, L., Xue, X., He, Q., Zhao, N., Chen, S., & Zhang, X. (2024) · Nutrients · doi:10.3390/nu17010047 · Cited by 7
Revisiting traditional Chinese exercise in prediabetes: effects on glycaemic and lipid metabolism – a systematic review and meta-analysis
Yan, R., Peng, W., Lu, D., He, J., Sun, J., Guan, L., Liu, S., & Li, D. (2025) · Diabetology & Metabolic Syndrome · doi:10.1186/s13098-025-01592-0 · Cited by 7
Improved detection of decreased glucose handling capacities via continuous glucose monitoring-derived indices
Sugimoto, H., Hironaka, K., Nakamura, T., Yamada, T., Miura, H., Otowa‐Suematsu, N., Fujii, M., Hirota, Y., Sakaguchi, K., Ogawa, W., et al. (2025) · Communications Medicine · doi:10.1038/s43856-025-00819-5 · Cited by 10
Adherence to lifestyle recommendations is associated with improved glycemic control and improved blood lipid levels in Korean adults with type 2 diabetes
Lim, J. H., Paik, H. Y., Lee, Y.-S., & Song, Y. (2013) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2013.06.009 · Cited by 7
The association of dietary total flavonoids and their subclasses with the risk of type 2 diabetes: a prospective cohort study
Woo, H. W., Kim, M. K., Kong, J.-S., Lee, J., Shin, M., Koh, S. B., Kim, H. C., & Kim, Y. (2024) · European Journal of Nutrition · doi:10.1007/s00394-024-03341-x · Cited by 8
Living with my diabetes – introducing eHealth into daily practices of patients with type 2 diabetes mellitus
van Leersum, C. M., Konrad, K., Bults, M., & den Ouden, M. E. M. (2024) · Digital Health · doi:10.1177/20552076241257052 · Cited by 7
Exercise-induced changes in body fat, upper leg skeletal muscle area, BMI and body weight in overweight people with risk of developing Type 2 Diabetes
Hansen, E., Landstad, B. J., Brønn, R., Gundersen, K. T., & Svebak, S. (2012) · Acta Kinesiologiae Universitatis Tartuensis · doi:10.12697/akut.2011.17.05 · Cited by 6
Physical Activity and Health in Women A Review of the Epidemiologic Evidence
Bassuk, S. S., & Manson, J. E. (2014) · American Journal of Lifestyle Medicine · Cited by 7
Pilot feasibility study of the Walking Away from Diabetes programme for adults with intellectual disabilities in two further education colleges: Process evaluation findings
Maine, A., Brown, M. J., Dickson, A., & Truesdale, M. (2019) · Journal of Applied Research in Intellectual Disabilities · doi:10.1111/jar.12593 · Cited by 7
Factors associated with undiagnosed type II diabetes mellitus, undiagnosed impaired fasting glucose and these patients’ quality of life in Lebanon
Hallit, S. R., Saade, S., Zeidan, R. K., Iskandar, K., Kheir, N., Youssef, L., Costantine, R., Hallit, R. R., & Salameh, P. (2019) · Journal of Public Health · doi:10.1093/pubmed/fdz051 · Cited by 7
Impact of methodological choices on a meta-analysis of real-world evidence comparing non-vitamin-K antagonist oral anticoagulants with vitamin K antagonists for the treatment of patients with non-valvular atrial fibrillation
Brière, J., Wu, O., Bowrin, K., Millier, A., Toumi, M., Taieb, V., Levy, P., & Coleman, C. I. (2019) · Current Medical Research and Opinion · doi:10.1080/03007995.2019.1647020 · Cited by 7
Prediction of type 2 diabetes risk in people with non-diabetic hyperglycaemia: model derivation and validation using UK primary care data
Coles, B., Khunti, K., Booth, S., Zaccardi, F., Davies, M. J., & Gray, L. J. (2020) · BMJ Open · doi:10.1136/bmjopen-2020-037937 · Cited by 8
Self-citation
Association between health‐related quality of life and impaired glucose metabolism in Iran: the Qazvin Metabolic Diseases Study
Ghorbani, A., Ziaee, A., Esmailzadehha, N., & Javadi, H. R. (2014) · Diabetic Medicine · doi:10.1111/dme.12415 · Cited by 7
Strategies to prevent the type 2 diabetes mellitus epidemic
Robertson, R. P., Kendall, D. M., & Seaquist, E. R. (2010) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2010.2 · Cited by 7
Screening for diabetes
Backholer, K., Chen, L., & Shaw, J. E. (2012) · Pathology · doi:10.1097/pat.0b013e32834e8e12 · Cited by 7
Diabetes prevention: Can insulin secretagogues do the job?
Westerhaus, B., Gosmanov, A. R., & Umpierrez, G. E. (2010) · Primary care diabetes · doi:10.1016/j.pcd.2010.11.002 · Cited by 7
Testing relationships: ethical arguments for screening for type 2 diabetes mellitus with HbA1C
Degeling, C., Rock, M. J., & Rogers, W. (2011) · Journal of Medical Ethics · doi:10.1136/medethics-2011-100086 · Cited by 8
Prevalence of Prediabetes and Its Association with Clustering of Cardiometabolic Risk Factors and Hyperinsulinemia Among U.S. Adolescents: National Health and Nutrition Examination Survey 2005-2006 Short title: Prediabetes Among U.S. Adolescents
Li, C., Ford, E. S., Zhao, G., & Mokdad, A. H. (2008) · Cited by 7
Interventions for prevention of type 2 diabetes in relatives: A systematic review
Dimova, E. D., Mohan, A., Swanson, V., & Evans, J. M. M. (2017) · Primary care diabetes · doi:10.1016/j.pcd.2017.04.003 · Cited by 7
Older People: Improving Health and Social Care
Dijkman, B. L., Roodbol, P. F., Mikkonen, Ì., Hobbelen, H. J. S. M., de Greef, M., Werkman, A., Weening-Verbree, L., van der Werf, F., Beenen, P., Zuidersma, J., et al. (2018) · Springer eBooks · doi:10.1007/978-3-319-97610-5 · Cited by 7
[Metabolic syndrome and live kidney donor: is this syndrome a contraindication to donation?].
Hernández, D., Alvarez, A., de Armas, A. A. P., Rufino, M., Porrini, E., & Torres, A. (2009) · PubMed · doi:10.3265/nefrologia.2009.29.1.20.1.en.full.pdf · Cited by 7
Do improvements in dietary behaviour contribute to cardiovascular risk factor reduction over and above cardio-protective medication in newly diagnosed diabetes patients?
Cooper, A., Schliemann, D., Long, G. H., Griffin, S. J., Simmons, R. K., & on behalf of the ADDITION-Cambridge study team (2014) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2014.79 · Cited by 7
Screening for Type 2 Diabetes in a High-Risk Population: Effects of a Negative Screening Test After 4 Years Follow-up
Willems, J. I., Otto, S. J., Klijs, B., & de Koning, H. J. (2013) · Annals of Behavioral Medicine · doi:10.1007/s12160-013-9525-3 · Cited by 7
Combined chromium and magnesium decreases insulin resistance more effectively than either alone.
Dou, M., Ma, Y., Ma, A. G., Han, L., Song, M. M., Wang, Y. G., Yao, M., Sun, X., Li, Y., Gao, S., et al. (2016) · PubMed · doi:10.6133/apjcn.092015.48 · Cited by 7
Risk of type 2 diabetes: health care provider perceptions of prevention adherence
Thomas, J. J., Moring, J. C., Harvey, T., Hobbs, T., & Lindt, A. (2016) · Applied Nursing Research · doi:10.1016/j.apnr.2016.03.002 · Cited by 8
Importance of Recalibrating Models for Type 2 Diabetes Onset Prediction: Application of the Diabetes Population Risk Tool on the Health and Retirement Study
Vettoretti, M., Longato, E., Camillo, B. D., & Facchinetti, A. (2018) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc.2018.8513554 · Cited by 7
Exercise to improve diabetic peripheral neuropathy: An additional option?
Vas, P. R. J., Pafili, K., & Παπάνας, Ν. (2018) · Neurophysiologie Clinique · doi:10.1016/j.neucli.2018.05.001 · Cited by 7
Fine-tuning of prediction of isolated impaired glucose tolerance: A quantitative clinical prediction model
Rambod, M., Hosseinpanah, F., Ardakani, E. M., Padyab, M., & Azizi, F. (2008) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2008.09.040 · Cited by 7
A call to action - the UN Resolution on diabetes
Prato, S. D. (2007) · International Journal of Clinical Practice · doi:10.1111/j.1742-1241.2007.01607.x · Cited by 7
Association between fruit, vegetable, seafood, and dairy intake and a reduction in the prevalence of type 2 diabetes in Qingdao, China.
Liang, J., Zhang, Y., Xue, A., Sun, J., Song, X., Bai, X., Ji, F., Gao, W., He, L., Pang, Z., et al. (2017) · PubMed · doi:10.6133/apjcn.012016.03 · Cited by 7
Derivation and validation of a simple risk score for undiagnosed diabetes for Tanzania and other African populations
Mayige, M. T. (2014) · Cited by 7
The effectiveness and cost-effectiveness of the NHS Diabetes Prevention Programme (NHS-DPP): the DIPLOMA long-term multimethod assessment
Bower, P., Soiland‐Reyes, C., Bennett, C., Brunton, L., Burch, P., Cameron, E., Chandola, T., Chatzi, G., Cotterill, S., French, D., et al. (2025) · Health and Social Care Delivery Research · doi:10.3310/mwkj5102 · Cited by 6
Incidence and predictors of type 2 diabetes mellitus in a population-based cohort study in Abu Dhabi
AlKetbi, L. B., AlKetbi, R. M., AlShamsi, M. S., Nagelkerke, N. J. D., Afandi, B. O., AlDobaee, M., AlKuwaiti, M., AlNeyadi, M., Humaid, A., AlAlawi, N., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-07631-0 · Cited by 6
Effects of childhood obesity on heart failure and its associated risk factors in the European population: A Mendelian randomization study
Kong, R., & Li, S. (2023) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2023.11.020 · Cited by 6
Prevalence of prediabetes in HIV-1 infected adults receiving antiretroviral therapy in Addis Ababa, Ethiopia.
Gebreyesus, H. A. (2015) · Cited by 6
The process of health behaviour change following participation in a randomised controlled trial targeting prediabetes: A qualitative study
Schmidt, K., Færch, K., Zoffmann, V., Amadid, H., & Varming, A. R. (2021) · Diabetic Medicine · doi:10.1111/dme.14748 · Cited by 8
Assessing the Feasibility and Acceptability of Health Coaching as a New Diabetes Management Approach for the People with Type 2 Diabetes in Saudi Arabia: A Protocol for a Mixed Methods Feasibility Study
Almulhim, A. N., Goyder, E., & Caton, S. J. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph192215089 · Cited by 7
Diabetic Retinopathy and Diabetic Macular Edema: Fighting the Emerging Global Burden
Bhattacharjee, H., Barman, M., & Garg, M. (2022) · Springer eBooks · doi:10.1007/978-981-19-7307-9_20 · Cited by 7
Wellness in Parkinson’s Disease: A Framework for Management Using a Holistic Culturally Sensitive Approach
Subramanian, I., PADRECC, W. L. A., Perepezko, K. M., Stone, B., Chaudhuri, К. R., & Pontone, G. M. (2023) · touchREVIEWS in Neurology · doi:10.17925/usn.2023.19.1.8 · Cited by 7
Risk prediction models for type 2 diabetes using either fasting plasma glucose or HbA1c in Chinese, Malay, and Indians: Results from three multi-ethnic Singapore cohorts
Seah, J. Y. H., Yao, J., Hong, Y., Lim, C. G. Y., Sabanayagam, C., Nusinovici, S., Gardner, D. S.-L., Loh, M. C. S., Müller‐Riemenschneider, F., Tan, C. S., et al. (2023) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2023.110878 · Cited by 7
Comorbidity and lack of education countered participation in a diabetes prevention self-management program
Maindal, H. T., Skriver, M. V., Kirkevold, M., Lauritzen, T., & Sandbæk, A. (2011) · Journal of Nursing and Healthcare of Chronic Illness · doi:10.1111/j.1752-9824.2011.01103.x · Cited by 6
External validation of two diabetes risk scores in a young UK South Asian population
Gray, L. J., Khunti, K., Wilmot, E. G., Yates, T. E., & Davies, M. J. (2014) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2014.03.018 · Cited by 6
Self-citation
Prevención de la diabetes de tipo 2. ¿Qué se puede hacer desde la atención primaria? La experiencia del DE-PLAN-CAT
Costa, B. (2012) · Avances en Diabetología · doi:10.1016/j.avdiab.2012.04.004 · Cited by 6
A Continuing Medical Education Needs Assessment of Primary Care Physicians' Knowledge Awareness of Prediabetes Care
Curran, V. R., Hollett, A., Allen, M., Steeves, J. M., & Dunbar, P. (2008) · Canadian Journal of Diabetes · doi:10.1016/s1499-2671(08)24007-4 · Cited by 6
The Impact of a Worksite-Based Diabetes Prevention Intervention: A Pilot Study
Clark, B. L., Boghani, S., Grullon, C., & Batista, M. (2016) · Population Health Management · doi:10.1089/pop.2016.0055 · Cited by 6
Is the success of the SLIMMER diabetes prevention intervention modified by socioeconomic status? A randomised controlled trial
Bukman, A. J., Duijzer, G., Haveman‐Nies, A., Jansen, S. C., ter Beek, J., Hiddink, G. J., & Feskens, E. J. M. (2017) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2017.05.002 · Cited by 6
Medications Affecting the Biochemical Conversion to Type 2 Diabetes: A Systematic Review and Meta-Analysis
Domecq, J. P., Prutsky, G. J., Elraiyah, T. A., Wang, Z., Mauck, K. F., Brito, J. P., Undavalli, C., Sundaresh, V., Prokop, L. J., Montori, V. M., et al. (2019) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2019-01269 · Cited by 8
Epidemiologie des Diabetes
Rathmann, W. (2010) · Der Diabetologe · doi:10.1007/s11428-010-0554-2 · Cited by 6
Vitamin D and ω-3 Polyunsaturated Fatty Acids towards a Personalized Nutrition of Youth Diabetes: A Narrative Lecture
Cadario, F. (2022) · Nutrients · doi:10.3390/nu14224887 · Cited by 6
Evidence Update On Obesity Prevention Across The Life-course
Hector, D., King, L. J., Hardy, L. L., Hebden, L., Espinel, P. T., & Rissel, C. E. (2012) · The Sydney eScholarship Repository (The University of Sydney) · Cited by 6
The Performance of the Finnish Diabetes Risk Score (FINDRISC) Questionaire for Screening Individuals with Undiagnosed Type 2 Diabetes and Dysglycaemia in Nigeria
Michael, O. A., Oluyombo, R., & Iwuala, S. O. (2017) · Journal of Advances in Medicine and Medical Research · doi:10.9734/bjmmr/2017/31022 · Cited by 6
A Review of the Impacts of Different Approaches for Diabetes Prevention and a Framework for Making Investment Decisions
Alva, M. L. (2018) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph15030522 · Cited by 6
One-hour plasma glucose combined with skin autofluorescence identifies subjects with pre-diabetes: the DIAPASON study
Sala, L. L., Tagliabue, E., de Candia, P., Prattichizzo, F., & Ceriello, A. (2020) · BMJ Open Diabetes Research & Care · doi:10.1136/bmjdrc-2020-001331 · Cited by 6
Assessment of Sudomotor Function to Predict Future Abnormalities of Glucose Tolerance in at Risk Population
Ramachandran, A., Moses, A., Snehalatha, C., Shetty, A. S., & Seeli, A. C. (2011) · Journal of Diabetes & Metabolism · doi:10.4172/2155-6156.1000125 · Cited by 6
Inadequate Description of Educational and Behavior Change Theories in Lifestyle Interventions for Type 2 Diabetes Prevention
Aagaard‐Hansen, J. (2014) · Journal of Diabetes & Metabolism · doi:10.4172/2155-6156.1000375 · Cited by 5
Trastornos metabólicos asociados con la evolución hacia la diabetes mellitus tipo 2 en una población en riesgo
Suárez, R. M. G., Amador, P., & Calzado, C. M. A. (2010) · Revista cubana de endocrinología · Cited by 5
Metabolic Syndrome and Ethnicity
Tillin, T., & Forouhi, N. G. (2011) · Wiley eBooks · doi:10.1002/9781444347319.ch2 · Cited by 6
Obesity/Overweight: Health Consequences
Bassuk, S. S., & Manson, J. E. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-803678-5.00308-8 · Cited by 6
Altered Risk for Cardiovascular Events With Changes in the Metabolic Syndrome Status
Park, S., Han, K., & Kim, D. K. (2020) · Annals of Internal Medicine · doi:10.7326/l20-0076 · Cited by 6
Intervention fidelity assessment: A sub‐study of the Norfolk Diabetes Prevention Study (NDPS)
Withers, T. M., Garner, N. J., Thorley, C. S., Kellett, J., Price, L., Auckland, S., Sheldon, J., Howe, A. C., Pascale, M., Smith, J. R., et al. (2023) · British Journal of Health Psychology · doi:10.1111/bjhp.12651 · Cited by 5
Carotenoid and retinol composition of South Asian foods commonly consumed in the UK
Khokhar, S., Roe, M. A., & Swan, G. (2011) · Journal of Food Composition and Analysis · doi:10.1016/j.jfca.2011.11.005 · Cited by 5
Preventing the Progression to Type 2 Diabetes Mellitus in Adults at High Risk: A Systematic Review And Network Meta-Analysis of Lifestyle, Pharmacological and Surgical Interventions
Stevens, J., Harvey, R. C., Johnson, M., & Khunti, K. (2014) · Value in Health · doi:10.1016/j.jval.2014.08.643 · Cited by 7
Self-citation
Measuring the social value of prevention and management of type 2 diabetes in a community setting.
Clifford, Z., Jones, M., Solomon-Moore, E., Kok, M. S. Y., & Kimberlee, R. H. (2017) · Advances in Social Sciences Research Journal · doi:10.14738/assrj.416.3315 · Cited by 5
A study protocol for a cluster randomized controlled trial to test the applicability of the South African diabetes prevention program in the Eastern Cape Province of South Africa
Hill, J., Yako, Y. Y., George, C., Musarurwa, H. T., Jordaan, E., & Kengne, A. P. (2023) · BMC Public Health · doi:10.1186/s12889-022-14884-1 · Cited by 6
Conducting a diabetes mellitus prevention trial in women with GDM in Pakistan: a feasibility study
Iqbal, R., Naz, S., Sheikh, S. S., Qureshi, R. N., Bhutta, S. Z., Yasmeen, H., Azam, I., & Gill, P. S. (2024) · Pilot and Feasibility Studies · doi:10.1186/s40814-024-01514-3 · Cited by 5
Diabetes advice for women with polycystic ovary syndrome: prevention, prevention, prevention
Mani, H., Khunti, K., Levy, M. J., & Davies, M. J. (2013) · Diabetes Management · doi:10.2217/dmt.13.54 · Cited by 5
Self-citation
Devenir maternel après un diabète gestationnel. Dépistage et prévention du diabète de type 2. Revue de la littérature
Verier‐Mine, O. (2010) · Journal de gynécologie, obstétrique et biologie de la reproduction. Supplément/Journal de gynécologie obstétrique et biologie de la reproduction · doi:10.1016/s0368-2315(10)70056-9 · Cited by 6
Pharmaceutical Interventions for Diabetes Prevention in Patients at Risk
Chatterjee, S., Davies, M. J., & Khunti, K. (2017) · American Journal of Cardiovascular Drugs · doi:10.1007/s40256-017-0239-y · Cited by 5
Self-citation
Diabetes Self-Management Education Programs: Current Scenario and Relevance in India
Kaur, R. (2017) · Epidemiology International · doi:10.24321/2455.7048.201709 · Cited by 5
A randomized general population study of the effects of repeated health checks on incident diabetes
Skaaby, T., Jørgensen, T., & Linneberg, A. R. (2018) · Endocrine · doi:10.1007/s12020-018-1542-3 · Cited by 5
Protocol for a phase III RCT and economic analysis of two exercise delivery methods in men with PC on ADT
Alibhai, S. M. H., Ritvo, P., Mina, D. S., Sabiston, C. M., Krahn, M. D., TOMLINSON, G. A., Matthew, A., Lukka, H. R., Warde, P. R., Durbano, S., et al. (2018) · BMC Cancer · doi:10.1186/s12885-018-4937-x · Cited by 6
Clinical Recognition and Management of Patients with Prediabetes
Njeru, J. W., Castro, M. R., Carta, K. G., Simon, G., & Caraballo, P. J. (2019) · Endocrine Practice · doi:10.4158/ep-2018-0485 · Cited by 6
Adherence to Predefined Dietary Patterns and Risk of Developing Type 2 Diabetes in the Canadian Adult Population
Tait, C. A., L’Abbé, M. R., Smith, P. M., Watson, T., Kornas, K., & Rosella, L. C. (2019) · Canadian Journal of Diabetes · doi:10.1016/j.jcjd.2019.06.002 · Cited by 7

Authors: Gillies, C. L., Abrams, K. R., Lambert, P. C., Cooper, N. J., Sutton, A. J., Hsu, R. T., & Khunti, K.
Affiliations: University of Leicester (GB)
Corresponding author: Gillies, Clare L
ORCID: Gillies, Clare L
Abrams, Keith R
Lambert, Paul C
Cooper, Nicola J
Sutton, Alex J
Khunti, Kamlesh
Venue: BMJ
Publisher: BMJ
Published: 2007-01-19
Volume: 334
Issue: 7588
Pages: 299
ISSN: 0007-1447 (ISSN-L)
0959-8138
1468-5833
DOI: 10.1136/bmj.39063.689375.55
PMC: PMC1796695
OpenAlex: W2096691922
Cited by: 1,171
References: 43
Citations by year: 2026: 12 · 2025: 19 · 2024: 38 · 2023: 38 · 2022: 40 · 2021: 47 · 2020: 56 · 2019: 56 · 2018: 51 · 2017: 78 · 2016: 74 · 2015: 75 · 2014: 98 · 2013: 97 · 2012: 100
FWCI: 9.97
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.bmj.org/licenses/tdm/1.0/terms-and-conditions.html (tdm)
Locations: BMJ (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Leicester Research Archive (University of Leicester) (submittedVersion)
HighWire Press Open Archive (submittedVersion)
Funders: Medical Research Council
Economic and Social Research Council
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Health Sciences › Medicine › Pharmacology (medical) › Pharmacology and Obesity Treatment
Keywords: type 2 diabetes prevention, impaired glucose tolerance, lifestyle intervention, pharmacological interventions, oral antidiabetic drugs, orlistat, diabetes progression, number needed to treat
MeSH terms: Diabetes Mellitus, Type 2, Humans, Hypoglycemic Agents, Life Style, Randomized Controlled Trials as Topic, Treatment Outcome, Publication Bias, Glucose Intolerance

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Pharmacological and lifestyle interventions to prevent or delay type 2 diabetes in people with impaired glucose tolerance: systematic review and meta-analysis

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks