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Effectiveness of early physiotherapy to prevent lymphoedema after surgery for breast cancer: randomised, single blinded, clinical trial

Open access
Torres Lacomba, M., Yuste Sanchez, M. J., Zapico Goni, A., Prieto Merino, D., Mayoral del Moral, O., Cerezo Tellez, E., Minayo Mogollon, E.·2010·BMJ

Abstract

OBJECTIVE: To determine the effectiveness of early physiotherapy in reducing the risk of secondary lymphoedema after surgery for breast cancer. DESIGN: Randomised, single blinded, clinical trial. SETTING: University hospital in Alcalá de Henares, Madrid, Spain. PARTICIPANTS: 120 women who had breast surgery involving dissection of axillary lymph nodes between May 2005 and June 2007. INTERVENTION: The early physiotherapy group was treated by a physiotherapist with a physiotherapy programme including manual lymph drainage, massage of scar tissue, and progressive active and action assisted shoulder exercises. This group also received an educational strategy. The control group received the educational strategy only. MAIN OUTCOME MEASURE: Incidence of clinically significant secondary lymphoedema (>2 cm increase in arm circumference measured at two adjacent points compared with the non-affected arm). RESULTS: 116 women completed the one year follow-up. Of these, 18 developed secondary lymphoedema (16%): 14 in the control group (25%) and four in the intervention group (7%). The difference was significant (P=0.01); risk ratio 0.28 (95% confidence interval 0.10 to 0.79). A survival analysis showed a significant difference, with secondary lymphoedema being diagnosed four times earlier in the control group than in the intervention group (intervention/control, hazard ratio 0.26, 95% confidence interval 0.09 to 0.79). CONCLUSION: Early physiotherapy could be an effective intervention in the prevention of secondary lymphoedema in women for at least one year after surgery for breast cancer involving dissection of axillary lymph nodes. TRIAL REGISTRATION: Current controlled trials ISRCTN95870846.

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Metadata

Authors
Torres Lacomba, M., Yuste Sanchez, M. J., Zapico Goni, A., Prieto Merino, D., Mayoral del Moral, O., Cerezo Tellez, E., & Minayo Mogollon, E.
Venue
BMJ
Publisher
BMJ
Published
2010-01-12
Volume
340
Issue
jan12 1
Pages
b5396-b5396
ISSN
  • 0007-1447 (ISSN-L)
  • 0959-8138
  • 1468-5833
OpenAlex
W1488738068
Cited by
385
References
35
FWCI
13.39
Type
journal article
Language
en
Open access
hybrid

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Torres Lacomba, M., Yuste Sanchez, M. J., Zapico Goni, A., Prieto Merino, D., Mayoral del Moral, O., Cerezo Tellez, E., & Minayo Mogollon, E. (2010). Effectiveness of early physiotherapy to prevent lymphoedema after surgery for breast cancer: randomised, single blinded, clinical trial. BMJ. https://doi.org/10.1136/bmj.b5396

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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