Drug-grapefruit juice interactions
Abstract
Two mechanisms are clear but individual responses vary
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Both intention-to-treat and per-protocol analyses will be reported following SPIRIT and CONSORT guideline recommendations.
“Finally, following SPIRIT and CONSORT guideline recommendations, both intention-to-treat and per-protocol analyses will be reported [34, 36].”
From An internet-based intervention for adjustment disorder (TAO): Study protocol for a randomized controlled trial (2018) · cites this paper as [36]
The trial will be conducted following CONSORT, CONSORT-EHELTH, and SPIRIT guidelines.
“The trial was registered on the ClinicalTrial.gov database as NCT02758418, and it will be conducted following the Consolidated Standards of Reporting Trials (CONSORT) [33], the CONSORT extension for Electronic and mobile Health Applications and onLine TeleHealth interventions (CONSORT-EHELTH) [34], and the SPIRIT guidelines (Standard Protocol Items: Recommendations for Intervention Trials) [35, 36”
From An internet-based intervention for adjustment disorder (TAO): Study protocol for a randomized controlled trial (2018) · cites this paper as [36]
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- Authors
- Pirmohamed, M.
- Affiliations
- University of Liverpool (GB)
- Corresponding author
- Pirmohamed, M.
- ORCID
- Pirmohamed, M.
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 2013-01-07
- Volume
- 346
- Issue
- jan07 1
- Pages
- f1-f1
- ISSN
- 1756-1833 (ISSN-L)
- OpenAlex
- W2148173750
- Cited by
- 140
- References
- 10
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 2 · 2023: 3 · 2022: 12 · 2021: 17 · 2020: 9 · 2019: 9 · 2018: 13 · 2017: 6 · 2016: 17 · 2015: 11 · 2014: 25 · 2013: 12
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- BMJ (publishedVersion)
- PubMed (publishedVersion)
- HighWire Press Open Archive (submittedVersion)
- Topics
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Pharmacogenetics and Drug Metabolism
- Health Sciences › Medicine › Oncology › Drug Transport and Resistance Mechanisms
- Health Sciences › Medicine › Complementary and alternative medicine › Complementary and Alternative Medicine Studies
- Keywords
- grapefruit juice, drug interactions, food-drug interactions, cytochrome P450 inhibition, interindividual variability, pharmacokinetics
- MeSH terms
- Beverages, Biological Availability, Cytochrome P-450 Enzyme System, Humans, Pharmacokinetics, Furocoumarins, Food-Drug Interactions, Organic Anion Transporters, Citrus paradisi, Cytochrome P-450 CYP3A
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